BG106457A - Метод за получаване на антибиотичен комбиниран състав - Google Patents

Метод за получаване на антибиотичен комбиниран състав

Info

Publication number
BG106457A
BG106457A BG106457A BG10645702A BG106457A BG 106457 A BG106457 A BG 106457A BG 106457 A BG106457 A BG 106457A BG 10645702 A BG10645702 A BG 10645702A BG 106457 A BG106457 A BG 106457A
Authority
BG
Bulgaria
Prior art keywords
organic
compound composition
antibiotic compound
mixture
antibiotic
Prior art date
Application number
BG106457A
Other languages
English (en)
Other versions
BG65499B1 (bg
Inventor
Sebastian Vogt
Matthias Schnabelrauch
Klaus-Dieter Kuehn
Original Assignee
Heraeus Kulzer GmbH & Co.KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer GmbH & Co.KG filed Critical Heraeus Kulzer GmbH & Co.KG
Publication of BG106457A publication Critical patent/BG106457A/bg
Publication of BG65499B1 publication Critical patent/BG65499B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Glanulating (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

По метода се получава антибиотична смес, включваща сол, която може да бъде подложена на пластична деформация, съдържаща поне един катионен компонент от протонизирана антибиотична база от групите на аминогликозидните, линкозамидните и тетрациклиновите антибиотици и поне един анионен компонент от групата на органичните сулфати и/или органични сулфонати, и/или мастно-кисели естери. Тя се използва като свързващ агент за фиксиране на неорганични компоненти и/или на възможни органични компоненти на сместа и за формуването й по време на добавяне на вода, по-специално чрез пресоване, екструзия, валцоване, календроване и процес на изглаждане.
BG106457A 2001-03-22 2002-02-27 Метод за получаване на антибиотични смеси BG65499B1 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10114364A DE10114364A1 (de) 2001-03-22 2001-03-22 Verfahren zur Herstellung von antibiotischen Kompositen

Publications (2)

Publication Number Publication Date
BG106457A true BG106457A (bg) 2002-10-31
BG65499B1 BG65499B1 (bg) 2008-10-31

Family

ID=7678771

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106457A BG65499B1 (bg) 2001-03-22 2002-02-27 Метод за получаване на антибиотични смеси

Country Status (29)

Country Link
US (1) US6942877B2 (bg)
EP (1) EP1243255B1 (bg)
JP (1) JP3950721B2 (bg)
CN (1) CN1221248C (bg)
AT (1) ATE311860T1 (bg)
AU (1) AU766912B2 (bg)
BG (1) BG65499B1 (bg)
BR (1) BR0201224A (bg)
CA (1) CA2378436C (bg)
CZ (1) CZ2002869A3 (bg)
DE (2) DE10114364A1 (bg)
DK (1) DK1243255T3 (bg)
EE (1) EE200200156A (bg)
ES (1) ES2249502T3 (bg)
GE (1) GEP20053449B (bg)
HR (1) HRP20020239B1 (bg)
HU (1) HUP0201044A2 (bg)
IL (1) IL148637A (bg)
MD (1) MD2517C2 (bg)
MX (1) MXPA02003004A (bg)
NO (1) NO20021391L (bg)
NZ (1) NZ517919A (bg)
PL (1) PL204984B1 (bg)
RU (1) RU2241490C2 (bg)
SA (1) SA02230035B1 (bg)
SK (1) SK286868B6 (bg)
UA (1) UA71992C2 (bg)
YU (1) YU18002A (bg)
ZA (1) ZA200202256B (bg)

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DE10114245A1 (de) * 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung
DE10262176B4 (de) * 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung von antibiotisch beschichteten porösen Körpern sowie Verwendung
DE10307103A1 (de) * 2003-02-19 2004-09-09 Schering Ag Antitumor wirksame 2-substituierte D-Homostra-1,3,5(10)-trien-3-yl sulfamate
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
DE102004060666B3 (de) 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
DE102005061290B4 (de) * 2005-12-20 2021-03-18 Heraeus Medical Gmbh Verfahren zur Herstellung von Antibiotikum-/Antibiotika-Partikeln und deren Verwendung
US9603941B2 (en) * 2006-01-24 2017-03-28 Minghui Chai Method of preparing dendritic drugs
DE102006007245A1 (de) * 2006-02-15 2007-08-23 Heraeus Kulzer Gmbh Implantatmaterial
BRPI0602372B8 (pt) 2006-05-18 2021-06-22 Einco Biomaterial Ltda processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado
WO2008006083A2 (en) 2006-07-07 2008-01-10 Surmodics, Inc. Beaded wound spacer device
US20080063681A1 (en) * 2006-09-11 2008-03-13 Ebi, L.P. Therapeutic bone replacement material
ATE421956T1 (de) * 2006-09-19 2009-02-15 Leibniz Inst Naturstoff Forsch Antibiotikum maduraphthalazin-salze mit verzögerter wirkstofffreigabe des wirkstoffs und deren verwendung
DE102006060938A1 (de) * 2006-12-20 2008-06-26 Wolter, Dietmar F., Prof. Dr. Materialdepot zur Abgabe eines antibakteriellen Wirkstoffmaterials
DE102007039871A1 (de) 2007-08-21 2009-02-26 Friedrich-Baur-Gmbh Weichgewebe-Implantat mit antibakterieller Wirkung
US9155671B2 (en) 2012-10-16 2015-10-13 Surmodics, Inc. Wound packing device and methods
RU2535067C1 (ru) * 2013-08-19 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" Биоинтегрируемый композитный материал и способ формирования покрытия на изделиях медицинского назначения с использованием биоинтегрируемого композитного материала
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
CN106721083A (zh) * 2016-12-21 2017-05-31 驻马店华中正大有限公司 一种土霉素预混剂及其制备方法
RU2729025C1 (ru) * 2019-07-19 2020-08-03 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр травматологии и ортопедии имени Н.Н. Приорова" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ТО им. Н.Н. Приорова" Минздрава России) Способ хирургического лечения гнойно-воспалительных процессов костных и мягкотканых структур опорно-двигательной системы пациента с использованием мягких спейсеров, импрегнированных антибактериальными средствами

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Also Published As

Publication number Publication date
MXPA02003004A (es) 2003-08-20
JP2002338472A (ja) 2002-11-27
HUP0201044A2 (hu) 2003-02-28
US20020192279A1 (en) 2002-12-19
SA02230035B1 (ar) 2007-04-15
DE50205147D1 (de) 2006-01-12
AU2755702A (en) 2002-09-26
PL352923A1 (en) 2002-09-23
BG65499B1 (bg) 2008-10-31
MD2517C2 (ro) 2005-03-31
EP1243255B1 (de) 2005-12-07
GEP20053449B (en) 2005-02-25
CN1376459A (zh) 2002-10-30
HRP20020239A2 (en) 2002-12-31
JP3950721B2 (ja) 2007-08-01
IL148637A0 (en) 2002-09-12
SK286868B6 (sk) 2009-06-05
EE200200156A (et) 2002-12-16
EP1243255A2 (de) 2002-09-25
ES2249502T3 (es) 2006-04-01
NZ517919A (en) 2003-08-29
EP1243255A3 (de) 2002-12-18
UA71992C2 (en) 2005-01-17
CN1221248C (zh) 2005-10-05
IL148637A (en) 2006-10-31
ZA200202256B (en) 2002-10-11
NO20021391L (no) 2002-09-23
CZ2002869A3 (cs) 2002-11-13
US6942877B2 (en) 2005-09-13
ATE311860T1 (de) 2005-12-15
MD2517B2 (ro) 2004-08-31
AU766912B2 (en) 2003-10-23
HU0201044D0 (bg) 2002-05-29
HRP20020239B1 (en) 2006-12-31
CA2378436A1 (en) 2002-09-22
SK3942002A3 (en) 2002-10-08
PL204984B1 (pl) 2010-02-26
YU18002A (sh) 2004-11-25
DE10114364A1 (de) 2002-10-02
CA2378436C (en) 2007-12-18
RU2241490C2 (ru) 2004-12-10
BR0201224A (pt) 2002-12-10
MD20020074A (en) 2002-11-30
NO20021391D0 (no) 2002-03-20
DK1243255T3 (da) 2006-03-27

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