BG108245A - Compositions containing imidazotriazinone for nasal application - Google Patents

Compositions containing imidazotriazinone for nasal application

Info

Publication number: BG108245A
Authority: BG; Bulgaria
Prior art keywords: imidazotriazinone; compositions containing; nasal application; nasal; application
Prior art date: 2001-04-12

Application number

BG108245A

Other languages

Bulgarian (bg)

English (en)

Inventor

Peter Serno

Andreas Ohm

Wolfgang Barth

Richard-Josef Bauer

Hans-Martin Siefert

Dieter Zimmer

Original Assignee

Bayer Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-12

Filing date

2003-10-09

Publication date

2005-01-31

2003-10-09 Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft

2005-01-31 Publication of BG108245A publication Critical patent/BG108245A/xx

Links

IJYHVZICHKCLMQ-UHFFFAOYSA-N imidazo[4,5-d]triazin-4-one Chemical compound O=C1N=NN=C2N=CN=C12 IJYHVZICHKCLMQ-UHFFFAOYSA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
229940099471 Phosphodiesterase inhibitor Drugs 0.000 abstract 1
230000003444 anaesthetic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Otolaryngology (AREA)
Anesthesiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BG108245A 2001-04-12 2003-10-09 Compositions containing imidazotriazinone for nasal application BG108245A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10118306A DE10118306A1 (de)	2001-04-12	2001-04-12	Imidazotriazinonhaltige Zusammensetzungen zur nasalen Applikation

Publications (1)

Publication Number	Publication Date
BG108245A true BG108245A (en)	2005-01-31

Family

ID=7681379

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG108245A BG108245A (en)	2001-04-12	2003-10-09	Compositions containing imidazotriazinone for nasal application

Country Status (25)

Country	Link
US (2)	US6740306B2 (fr)
EP (1)	EP1381368A2 (fr)
JP (1)	JP2004525968A (fr)
KR (1)	KR20030087072A (fr)
CN (1)	CN1537004A (fr)
AR (1)	AR035821A1 (fr)
BG (1)	BG108245A (fr)
BR (1)	BR0208813A (fr)
CA (1)	CA2443639A1 (fr)
CZ (1)	CZ20032752A3 (fr)
DE (1)	DE10118306A1 (fr)
DO (1)	DOP2002000373A (fr)
EC (1)	ECSP034795A (fr)
EE (1)	EE200300501A (fr)
GT (1)	GT200200070A (fr)
HU (1)	HUP0303877A3 (fr)
IL (1)	IL158255A0 (fr)
MX (1)	MXPA03009314A (fr)
NO (1)	NO20034556L (fr)
PE (1)	PE20021035A1 (fr)
PL (1)	PL363033A1 (fr)
RU (1)	RU2003133143A (fr)
SK (1)	SK12682003A3 (fr)
UY (1)	UY27256A1 (fr)
WO (1)	WO2002083674A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002089808A1 (fr) *	2001-05-09	2002-11-14	Bayer Healthcare Ag	Nouvelle utilisation d'imidazotriazinones substituees 2-phenyl
DE102004023069A1 (de) *	2004-05-11	2005-12-08	Bayer Healthcare Ag	Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
ZA200704869B (en) *	2004-12-23	2009-02-25	Roxro Pharma Inc	Therapeutic compositions for intranasal administration of ketorolac
DE102005001989A1 (de) *	2005-01-15	2006-07-20	Bayer Healthcare Ag	Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009241A1 (de) *	2005-03-01	2006-09-07	Bayer Healthcare Ag	Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) *	2005-03-01	2006-09-07	Bayer Healthcare Ag	Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
CA2612917A1 (fr) *	2005-06-23	2007-01-04	Schering Corporation	Formulations orales a absorption rapide d'inhibiteurs de la pde5
JP2009509984A (ja) *	2005-09-29	2009-03-12	バイエル・ヘルスケア・アクチェンゲゼルシャフト	泌尿器系障害の処置用のｐｄｅ阻害剤およびそれらの組合せ
WO2008151734A1 (fr) *	2007-06-13	2008-12-18	Bayer Schering Pharma Aktiengesellschaft	Inhibiteurs de la phosphodiestérase (pde) destinés au traitement des troubles de l'audition
WO2009152369A1 (fr) *	2008-06-13	2009-12-17	Roxro Pharma, Inc.	Formulation pharmaceutique du kétorolac pour une administration intranasale
US8277781B2 (en) *	2009-03-13	2012-10-02	Luitpold Pharmaceuticals, Inc.	Device for intranasal administration
US8551454B2 (en) *	2009-03-13	2013-10-08	Luitpold Pharmaceuticals, Inc.	Device for intranasal administration
WO2017168174A1 (fr)	2016-04-02	2017-10-05	N4 Pharma Uk Limited	Nouvelles formes pharmaceutiques du sildénafil
WO2020006606A1 (fr) *	2018-07-05	2020-01-09	Helium 3 Resources Pty Ltd	Composition pharmaceutique et utilisation correspondante
SE542968C2 (en) *	2018-10-26	2020-09-22	Lindahl Anders	Treatment of osteoarthritis
BR112022024098A2 (pt) *	2020-05-26	2023-02-07	Strategic Drug Solutions Inc	Formulações e métodos para tratar a disfunção erétil

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4602099A (en) *	1973-04-02	1986-07-22	Merrell Dow Pharmaceuticals Inc.	Antirhinovirus agents
GB9013750D0 (en)	1990-06-20	1990-08-08	Pfizer Ltd	Therapeutic agents
GB9311920D0 (en)	1993-06-09	1993-07-28	Pfizer Ltd	Therapeutic agents
GB9514465D0 (en)	1995-07-14	1995-09-13	Glaxo Lab Sa	Chemical compounds
GB9514473D0 (en)	1995-07-14	1995-09-13	Glaxo Lab Sa	Chemical compounds
EP0985671B1 (fr)	1996-05-31	2003-04-02	Mochida Pharmaceutical Co., Ltd.	DERIVES DE PYRIDOCARBAZOLE AYANT UN EFFET INHIBITEUR DE cGMP-PDE
GB2315673A (en) *	1996-08-01	1998-02-11	Merck & Co Inc	Treatment of migraine
WO1998053819A1 (fr) *	1997-05-29	1998-12-03	Mochida Pharmaceutical Co., Ltd.	Agent therapeutique destine a traiter l'anerection
AU9214498A (en)	1997-09-23	1999-04-12	Eli Lilly And Company	Treatment of attention-deficit/hyperactivity disorder
CA2395558C (fr)	1997-11-12	2007-07-17	Bayer Aktiengesellschaft	Imidazotriazinones a substitution 2-phenyle utilisees comme inhibiteurs des phosphodiesterases
TWI223598B (en) *	1998-06-22	2004-11-11	Pfizer Ireland Pharmaceuticals	An intranasal pharmaceutical composition for the treatment of male erectile dysfunction or female sexual disorders, an intranasal delivery system or device and sildenafil mesylate
WO2000000199A1 (fr) *	1998-06-26	2000-01-06	Nastech Pharmaceutical Company, Inc.	Administration intranasale de citrate de sildenafil
BR9916162A (pt) *	1998-12-14	2001-09-04	Cellegy Pharma Inc	Composição e método para o tratamento de um distúrbio anorretal e para controlar a dor associada com o mesmo

2001
- 2001-04-12 DE DE10118306A patent/DE10118306A1/de not_active Withdrawn
2002
- 2002-04-03 MX MXPA03009314A patent/MXPA03009314A/es unknown
- 2002-04-03 EP EP02732548A patent/EP1381368A2/fr not_active Withdrawn
- 2002-04-03 HU HU0303877A patent/HUP0303877A3/hu unknown
- 2002-04-03 CN CNA028114574A patent/CN1537004A/zh active Pending
- 2002-04-03 WO PCT/EP2002/003663 patent/WO2002083674A2/fr not_active Ceased
- 2002-04-03 PL PL02363033A patent/PL363033A1/xx not_active Application Discontinuation
- 2002-04-03 CA CA002443639A patent/CA2443639A1/fr not_active Abandoned
- 2002-04-03 KR KR10-2003-7013280A patent/KR20030087072A/ko not_active Withdrawn
- 2002-04-03 SK SK1268-2003A patent/SK12682003A3/sk unknown
- 2002-04-03 EE EEP200300501A patent/EE200300501A/xx unknown
- 2002-04-03 CZ CZ20032752A patent/CZ20032752A3/cs unknown
- 2002-04-03 IL IL15825502A patent/IL158255A0/xx unknown
- 2002-04-03 RU RU2003133143/15A patent/RU2003133143A/ru not_active Application Discontinuation
- 2002-04-03 JP JP2002581429A patent/JP2004525968A/ja active Pending
- 2002-04-03 BR BR0208813-4A patent/BR0208813A/pt not_active Application Discontinuation
- 2002-04-04 DO DO2002000373A patent/DOP2002000373A/es unknown
- 2002-04-10 AR ARP020101322A patent/AR035821A1/es not_active Application Discontinuation
- 2002-04-11 UY UY27256A patent/UY27256A1/es not_active Application Discontinuation
- 2002-04-11 PE PE2002000303A patent/PE20021035A1/es not_active Application Discontinuation
- 2002-04-11 US US10/122,694 patent/US6740306B2/en not_active Expired - Fee Related
- 2002-04-11 GT GT200200070A patent/GT200200070A/es unknown
2003
- 2003-10-08 EC EC2003004795A patent/ECSP034795A/es unknown
- 2003-10-09 BG BG108245A patent/BG108245A/xx unknown
- 2003-10-10 NO NO20034556A patent/NO20034556L/no not_active Application Discontinuation
2004
- 2004-03-30 US US10/813,801 patent/US20040248891A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1381368A2 (fr)	2004-01-21
BR0208813A (pt)	2004-03-09
EE200300501A (et)	2003-12-15
ECSP034795A (es)	2003-12-01
US20040248891A1 (en)	2004-12-09
DE10118306A1 (de)	2002-10-17
WO2002083674A3 (fr)	2003-01-09
CZ20032752A3 (cs)	2004-01-14
NO20034556D0 (no)	2003-10-10
US6740306B2 (en)	2004-05-25
AR035821A1 (es)	2004-07-14
CA2443639A1 (fr)	2002-10-24
PL363033A1 (en)	2004-11-15
IL158255A0 (en)	2004-05-12
HUP0303877A3 (en)	2005-05-30
JP2004525968A (ja)	2004-08-26
SK12682003A3 (sk)	2004-03-02
DOP2002000373A (es)	2002-11-30
WO2002083674A2 (fr)	2002-10-24
HUP0303877A2 (hu)	2004-03-29
KR20030087072A (ko)	2003-11-12
UY27256A1 (es)	2002-11-29
GT200200070A (es)	2003-01-31
MXPA03009314A (es)	2004-03-10
RU2003133143A (ru)	2005-04-10
US20030022894A1 (en)	2003-01-30
CN1537004A (zh)	2004-10-13
PE20021035A1 (es)	2002-11-29
NO20034556L (no)	2003-12-10

Publication	Publication Date	Title
BG108245A (en)	2005-01-31	Compositions containing imidazotriazinone for nasal application
AP2001002204A0 (en)	2001-09-30	Pyrazole derivatives.
TW200518771A (en)	2005-06-16	Formulations for coated microprojections containing non-volatile counterions
PL361404A1 (en)	2004-10-04	Synergistic combinations comprising a renin inhibitor for cardiovascular diseases
MXPA02012033A (es)	2003-04-25	Derivados de 2-aminocarbonil-9h-purina.
TNSN04141A1 (en)	2007-03-12	NEW COMPOUNDS - DDP - IV difluor
MXPA03010207A (es)	2004-03-10	Nuevas 4-anilinoquinolin-3-carboxamidas.
GB0127903D0 (en)	2002-01-16	Improvements relating to organic compounds
AU2003228770A8 (en)	2003-11-11	Substituted pyrazolopyrimidines
TNSN07235A1 (en)	2008-11-21	Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride
MY126917A (en)	2006-10-31	Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors
TW200621737A (en)	2006-07-01	2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
IL163777A0 (en)	2005-12-18	Kinase inhibitors
ZA200404752B (en)	2005-04-26	6-aminomorphinane derivatives method for the production and use thereof
UA96759C2 (en)	2011-12-12	2-ARYLINDOLE DERIVATIVES AS mPGES-I INHIBITORS
MXPA04006266A (es)	2004-09-27	Pirimidotriazinas como inhibidores de fosfatasa.
BR0307595A (pt)	2005-02-01	Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico
IL160819A0 (en)	2004-08-31	Novel compounds and compositions as cathepsin inhibitors
IL159125A0 (en)	2004-05-12	Novel compounds and compositions as cathepsin inhibitors
MXPA04003755A (es)	2004-07-23	Endoprotesis vasculares.
AU2002343661A1 (en)	2003-06-23	Modified prostaglandin compounds and analogs thereof, compositions containing the same useful for the teatment of cancer
CO5580729A2 (es)	2005-11-30	Composiciones nutricionales que comprenden cistationina
DE60201074D1 (en)	2004-09-30	Pyrazolopyridinderivate
WO2002083108A3 (fr)	2003-04-10	Compositions pour administration nasale
PT1326838E (pt)	2008-07-08	Novas formas cristalinas de um inibidor do factor xa