BG108459A - Antitumoral formulations of thioxanthenone - Google Patents

Antitumoral formulations of thioxanthenone

Info

Publication number: BG108459A
Authority: BG; Bulgaria
Prior art keywords: thioxanthenone; antitumoral; formulations; oxothioxanthen; diethylamino
Prior art date: 2001-06-28

Application number

BG108459A

Other languages

Bulgarian (bg)

English (en)

Inventor

Ross Blundell

Edward Baker

Original Assignee

Sanofi-Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-28

Filing date

2003-12-16

Publication date

2005-02-28

2003-12-16 Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis

2005-02-28 Publication of BG108459A publication Critical patent/BG108459A/xx

Links

238000009472 formulation Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
230000000259 anti-tumor effect Effects 0.000 title 1
YRHRIQCWCFGUEQ-UHFFFAOYSA-N thioxanthen-9-one Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3SC2=C1 YRHRIQCWCFGUEQ-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 2
238000000034 method Methods 0.000 abstract 1
GWLFIMOOGVXSMZ-UHFFFAOYSA-N n-[[1-[2-(diethylamino)ethylamino]-7-methoxy-9-oxothioxanthen-4-yl]methyl]formamide Chemical compound S1C2=CC=C(OC)C=C2C(=O)C2=C1C(CNC=O)=CC=C2NCCN(CC)CC GWLFIMOOGVXSMZ-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BG108459A 2001-06-28 2003-12-16 Antitumoral formulations of thioxanthenone BG108459A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0115893.0A GB0115893D0 (en)	2001-06-28	2001-06-28	Formulations

Publications (1)

Publication Number	Publication Date
BG108459A true BG108459A (en)	2005-02-28

Family

ID=9917582

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG108459A BG108459A (en)	2001-06-28	2003-12-16	Antitumoral formulations of thioxanthenone

Country Status (22)

Country	Link
US (1)	US20050176619A1 (pl)
EP (1)	EP1406699A1 (pl)
JP (1)	JP2004536099A (pl)
KR (1)	KR20040030709A (pl)
CN (1)	CN1520325A (pl)
AR (1)	AR034621A1 (pl)
BG (1)	BG108459A (pl)
BR (1)	BR0210671A (pl)
CA (1)	CA2451195A1 (pl)
CZ (1)	CZ20033434A3 (pl)
EE (1)	EE200400041A (pl)
GB (1)	GB0115893D0 (pl)
HR (1)	HRP20031048A2 (pl)
HU (1)	HUP0402039A2 (pl)
IL (1)	IL159206A0 (pl)
IS (1)	IS7070A (pl)
MX (1)	MXPA03012064A (pl)
NO (1)	NO20035668D0 (pl)
PL (1)	PL367636A1 (pl)
RU (1)	RU2003136086A (pl)
SK (1)	SK15492003A3 (pl)
WO (1)	WO2003002202A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2503719T3 (es) *	2005-02-11	2014-10-07	Immunogen, Inc.	Procedimiento para preparar conjugados de anticuerpos y de maitansinoides
WO2014081715A1 (en) *	2012-11-20	2014-05-30	Vita Naturale, Llc	Compositions and methods for their dermatological use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5346917A (en) *	1991-06-10	1994-09-13	Sterling Winthrop Inc.	Thioxanthenone antitumor agents
US5665760A (en) *	1995-09-18	1997-09-09	Sanofi Winthrop, Inc.	Lyophilized thioxanthenone antitumor agents
US20030022920A1 (en) *	2001-06-19	2003-01-30	Christoph Ullmer	1-Methyl-4- (3-ethoxy-9H-thioxanthene-9-ylidene) -piperidine and its use as 5-HT2B/H1 receptor antagonist

2001
- 2001-06-28 GB GBGB0115893.0A patent/GB0115893D0/en not_active Ceased
2002
- 2002-06-24 AR ARP020102369A patent/AR034621A1/es not_active Application Discontinuation
- 2002-06-28 IL IL15920602A patent/IL159206A0/xx unknown
- 2002-06-28 EP EP02748985A patent/EP1406699A1/en not_active Withdrawn
- 2002-06-28 BR BR0210671-0A patent/BR0210671A/pt not_active IP Right Cessation
- 2002-06-28 JP JP2003508438A patent/JP2004536099A/ja active Pending
- 2002-06-28 CZ CZ20033434A patent/CZ20033434A3/cs unknown
- 2002-06-28 EE EEP200400041A patent/EE200400041A/xx unknown
- 2002-06-28 RU RU2003136086/15A patent/RU2003136086A/ru not_active Application Discontinuation
- 2002-06-28 WO PCT/GB2002/003012 patent/WO2003002202A1/en not_active Ceased
- 2002-06-28 KR KR10-2003-7016976A patent/KR20040030709A/ko not_active Withdrawn
- 2002-06-28 CA CA002451195A patent/CA2451195A1/en not_active Abandoned
- 2002-06-28 US US10/480,692 patent/US20050176619A1/en not_active Abandoned
- 2002-06-28 MX MXPA03012064A patent/MXPA03012064A/es not_active Application Discontinuation
- 2002-06-28 HR HR20031048A patent/HRP20031048A2/xx not_active Application Discontinuation
- 2002-06-28 PL PL02367636A patent/PL367636A1/pl not_active Application Discontinuation
- 2002-06-28 HU HU0402039A patent/HUP0402039A2/hu unknown
- 2002-06-28 SK SK1549-2003A patent/SK15492003A3/sk unknown
- 2002-06-28 CN CNA028127552A patent/CN1520325A/zh active Pending
2003
- 2003-12-11 IS IS7070A patent/IS7070A/is unknown
- 2003-12-16 BG BG108459A patent/BG108459A/xx unknown
- 2003-12-18 NO NO20035668A patent/NO20035668D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0402039A2 (hu)	2005-01-28
WO2003002202A1 (en)	2003-01-09
SK15492003A3 (sk)	2004-06-08
JP2004536099A (ja)	2004-12-02
MXPA03012064A (es)	2004-03-26
IS7070A (is)	2003-12-11
AR034621A1 (es)	2004-03-03
CN1520325A (zh)	2004-08-11
RU2003136086A (ru)	2005-05-27
BR0210671A (pt)	2004-10-13
CZ20033434A3 (cs)	2004-08-18
EP1406699A1 (en)	2004-04-14
NO20035668D0 (no)	2003-12-18
IL159206A0 (en)	2004-06-01
CA2451195A1 (en)	2003-01-09
PL367636A1 (pl)	2005-03-07
US20050176619A1 (en)	2005-08-11
KR20040030709A (ko)	2004-04-09
EE200400041A (et)	2004-04-15
GB0115893D0 (en)	2001-08-22
HRP20031048A2 (en)	2004-04-30

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