BG108605A - Използване на състави при лечението на рак - Google Patents

Използване на състави при лечението на рак Download PDF

Info

Publication number: BG108605A
Authority: BG; Bulgaria
Prior art keywords: compound; alkyl; methyl; thio; thiazolyl
Prior art date: 2001-08-31

Application number

BG108605A

Other languages

Bulgarian (bg)

English (en)

Inventor

Kevin Webster

Spencer Kimball

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-31

Filing date

2004-02-25

Publication date

2005-03-31

2004-02-25 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2005-03-31 Publication of BG108605A publication Critical patent/BG108605A/bg

Links

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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Inorganic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BG108605A 2001-08-31 2004-02-25 Използване на състави при лечението на рак BG108605A (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US31636901P	2001-08-31	2001-08-31

Publications (1)

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BG108605A true BG108605A (bg)	2005-03-31

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BG108605A BG108605A (bg)	2001-08-31	2004-02-25	Използване на състави при лечението на рак

Country Status (10)

Country	Link
US (1)	US20030114504A1 (pl)
EP (1)	EP1429764A1 (pl)
JP (1)	JP2005504065A (pl)
BG (1)	BG108605A (pl)
CZ (1)	CZ2004287A3 (pl)
EE (1)	EE200400074A (pl)
HU (1)	HUP0402341A3 (pl)
PL (1)	PL368035A1 (pl)
SK (1)	SK1102004A3 (pl)
WO (1)	WO2003020272A1 (pl)

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US6204388B1 (en) *	1996-12-03	2001-03-20	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
US6242469B1 (en)	1996-12-03	2001-06-05	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
WO2004018478A2 (en)	2002-08-23	2004-03-04	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US7649006B2 (en)	2002-08-23	2010-01-19	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
WO2004071440A2 (en) *	2003-02-06	2004-08-26	Bristol-Myers Squibb Company	Thiazolyl-based compounds useful as kinase inhibitors
WO2005070020A2 (en) *	2004-01-23	2005-08-04	The Regents Of The University Of Colorado	Gefitinib sensitivity-related gene expression and products and methods related thereto
US20080113874A1 (en) *	2004-01-23	2008-05-15	The Regents Of The University Of Colorado	Gefitinib sensitivity-related gene expression and products and methods related thereto
US7951780B2 (en)	2004-02-25	2011-05-31	Astellas Pharma Inc.	Antitumor agent
EP2527460B1 (en)	2004-05-27	2014-12-24	The Regents of The University of Colorado	Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients
KR20080003334A (ko) *	2005-03-11	2008-01-07	더 리젠트스 오브 더 유니버시티 오브 콜로라도	암 세포를 표피 성장 인자 억제제에 대해 감작화시키는히스톤 데아세틸라제 억제제
WO2008036954A1 (en) *	2006-09-21	2008-03-27	Sunesis Pharmaceuticals, Inc.	Use of n- [5- [ [ [5- (1, 1-dimethylethyl) -2-oxazoyl] methyl] thio] -2-thiazolyl] -4-piperidinecarboxamide
US8518930B2 (en)	2008-07-29	2013-08-27	Nerviano Medical Sciences S.R.L.	Therapeutic combination comprising a CDKS inhibitor and an antineoplastic agent

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CA1088049A (en) *	1975-06-03	1980-10-21	Takashi Masugi	3-substituted-7-substituted alkanamido-3-cephem-4- carboxylic acid compounds and processes for preparation thereof
US4214852A (en) *	1978-04-20	1980-07-29	General Electric Company	Variable turbine vane assembly
US6040321A (en) *	1997-11-12	2000-03-21	Bristol-Myers Squibb Company	Aminothiazole inhibitors of cyclin dependent kinases
US6262096B1 (en) *	1997-11-12	2001-07-17	Bristol-Myers Squibb Company	Aminothiazole inhibitors of cyclin dependent kinases
US6465448B1 (en) *	1999-08-13	2002-10-15	Case Western Reserve University	Methoxyamine potentiation of temozolomide anti-cancer activity
CA2440555A1 (en) *	2001-03-14	2002-09-19	Bristol-Myers Squibb Company	Combination of epothilone analogs and chemotherapeutic agents for the treatment of proliferative diseases

2002
- 2002-08-13 HU HU0402341A patent/HUP0402341A3/hu unknown
- 2002-08-13 JP JP2003524579A patent/JP2005504065A/ja active Pending
- 2002-08-13 WO PCT/US2002/026155 patent/WO2003020272A1/en not_active Ceased
- 2002-08-13 SK SK110-2004A patent/SK1102004A3/sk unknown
- 2002-08-13 EE EEP200400074A patent/EE200400074A/xx unknown
- 2002-08-13 PL PL02368035A patent/PL368035A1/pl not_active Application Discontinuation
- 2002-08-13 EP EP02759384A patent/EP1429764A1/en not_active Withdrawn
- 2002-08-13 CZ CZ2004287A patent/CZ2004287A3/cs unknown
- 2002-08-27 US US10/228,544 patent/US20030114504A1/en not_active Abandoned
2004
- 2004-02-25 BG BG108605A patent/BG108605A/bg unknown

Also Published As

Publication number	Publication date
HUP0402341A2 (hu)	2005-02-28
EE200400074A (et)	2004-06-15
JP2005504065A (ja)	2005-02-10
CZ2004287A3 (cs)	2004-10-13
US20030114504A1 (en)	2003-06-19
SK1102004A3 (sk)	2005-05-05
PL368035A1 (pl)	2005-03-21
WO2003020272A1 (en)	2003-03-13
EP1429764A1 (en)	2004-06-23
HUP0402341A3 (en)	2005-11-28

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