BG36936A3 - Метод за получаване на цефалоспоринови антибиотици - Google Patents

Метод за получаване на цефалоспоринови антибиотици

Info

Publication number
BG36936A3
BG36936A3 BG055737A BG5573782A BG36936A3 BG 36936 A3 BG36936 A3 BG 36936A3 BG 055737 A BG055737 A BG 055737A BG 5573782 A BG5573782 A BG 5573782A BG 36936 A3 BG36936 A3 BG 36936A3
Authority
BG
Bulgaria
Prior art keywords
cephalosporin antibiotics
obtaining
obtaining cephalosporin
antibiotics
proven
Prior art date
Application number
BG055737A
Other languages
Bulgarian (bg)
English (en)
Inventor
William Lunn
John Shakle
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG36936A3 publication Critical patent/BG36936A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG055737A 1981-03-11 1982-03-10 Метод за получаване на цефалоспоринови антибиотици BG36936A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/242,792 US4336253A (en) 1981-03-11 1981-03-11 Cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
BG36936A3 true BG36936A3 (bg) 1985-02-15

Family

ID=22916202

Family Applications (1)

Application Number Title Priority Date Filing Date
BG055737A BG36936A3 (bg) 1981-03-11 1982-03-10 Метод за получаване на цефалоспоринови антибиотици

Country Status (21)

Country Link
US (1) US4336253A (de)
EP (1) EP0060144A3 (de)
JP (1) JPS57165393A (de)
KR (1) KR830009119A (de)
AU (1) AU8091182A (de)
BG (1) BG36936A3 (de)
CA (1) CA1177066A (de)
CS (1) CS238620B2 (de)
DD (1) DD201599A5 (de)
DK (1) DK100982A (de)
ES (1) ES8303426A1 (de)
FI (1) FI820806A7 (de)
GB (1) GB2094309B (de)
GR (1) GR74714B (de)
IL (1) IL65185A0 (de)
NZ (1) NZ199959A (de)
PH (1) PH17022A (de)
PL (1) PL130568B1 (de)
PT (1) PT74558B (de)
RO (1) RO82962B (de)
ZA (1) ZA821525B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4450270A (en) * 1981-10-02 1984-05-22 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4616081A (en) * 1982-07-07 1986-10-07 Asahi Kasei Kogyo Kabushiki Kaisha Cephalosporin compounds
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
ATE177104T1 (de) * 1984-11-23 1999-03-15 Biochemie Gmbh Cephalosporinderivative
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US7847093B2 (en) * 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime
DE602004028111D1 (de) 2003-04-16 2010-08-26 Sandoz Ag Verfahren zur herstellung von cefepim
EP1773845A1 (de) * 2004-07-16 2007-04-18 Hetero Drugs Limited Verfahren zur herstellung reiner cephalosporinzwischenprodukte
WO2013036783A2 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
KR102329764B1 (ko) 2013-03-15 2021-11-23 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US20140275000A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792047A (en) * 1971-12-07 1974-02-12 Glaxo Lab Ltd N-(7,2'-thienylacetamidoceph-3-em-3-ylmethyl)-3"or 4"-n-hydroxyloweralkylcarbamoyl-pyridinium-4-carboxylates
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE2760484C2 (de) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
JPS52125188A (en) 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
KR830000606B1 (ko) 1978-05-26 1983-03-17 헤롤드 월터 마틴 세팔로스포린 항생제의 제조방법
GB2027692B (en) 1978-05-26 1983-02-09 Glaxo Group Ltd Cephalosporin antibiotics
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
ES8103103A1 (es) 1979-02-23 1981-02-16 Glaxo Group Ltd Un procedimiento para la preparacion de un antibiotico de cefalosporina.
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Also Published As

Publication number Publication date
EP0060144A3 (de) 1983-09-14
KR830009119A (ko) 1983-12-17
DD201599A5 (de) 1983-07-27
FI820806L (fi) 1982-09-12
AU8091182A (en) 1982-09-16
ZA821525B (en) 1983-03-30
CA1177066A (en) 1984-10-30
PT74558B (en) 1984-11-27
JPS57165393A (en) 1982-10-12
IL65185A0 (en) 1982-05-31
NZ199959A (en) 1985-08-16
PT74558A (en) 1982-04-01
ES510307A0 (es) 1983-02-01
GR74714B (de) 1984-07-06
PH17022A (en) 1984-05-11
ES8303426A1 (es) 1983-02-01
GB2094309B (en) 1985-03-27
PL130568B1 (en) 1984-08-31
RO82962A (ro) 1984-01-14
DK100982A (da) 1982-09-12
EP0060144A2 (de) 1982-09-15
CS238620B2 (en) 1985-12-16
RO82962B (ro) 1984-01-30
GB2094309A (en) 1982-09-15
US4336253A (en) 1982-06-22
PL235396A1 (de) 1982-09-27
FI820806A7 (fi) 1982-09-12

Similar Documents

Publication Publication Date Title
BG37995A3 (en) Method for preparing derivatives of 2- cyanbenzimidazol
BG37226A3 (en) Method for preparing derivatives of alkane acids
BG39293A3 (bg) Метод за получаване на карбоксиалкилни дипептиди
BG38334A3 (en) Method for preparing pyrolidinic derivatives
DK100982A (da) Fremgangsmaade til fremstilling af cephalosporinantibiotika
BG35328A3 (en) Method for preparing imidodisulphamidic derivatives
BG34453A3 (en) Method for obtaining penicilines and cephalosporines
BG38163A3 (bg) Метод за получаване на пиримидони
BG31376A3 (bg) Метод за получаване на фенетоноламини
BG36348A3 (en) Method for preparing thienopyridinon derivatives
BG37838A3 (bg) Метод за получаване на цефалоспорини
BG31648A3 (en) Method for obtaining of cephalosporine
BG37525A3 (en) Method for preparing n- substituted flavon- 8- carbonamides
BG37992A3 (bg) Метод за получаване на производни на бензамида
BG38638A3 (bg) Метод за получаване на арилциклобутил-аминопроизводни
BG39639A3 (bg) Метод за получаване на 1н, 3н- пироло/1,2-с/ тиазолови производни
BG40803A3 (bg) Метод за получаване на арилциклобутилалкиламинови производни
BG36935A3 (en) Method for preparing benzodiazepine compounds
BG34910A3 (en) Method for preparing cephalosporines
BG35897A3 (bg) Метод за получаване на 5-(дихидрокси-фенокси)-1н-тетразоли
BG37839A3 (bg) Метод за получаване на производни на ортокондензиран пирол
BG38338A3 (en) Method for preparing 6 alpha- methylhydrocortisonic derivatives
BG35899A3 (bg) Метод за получаване на пеницилинови и цефалоспоринови иминохалогениди
BG37380A3 (en) Method for preparing 1, 1- dioxo- 6- halo (or 6, 6- dihalo)- penicillanoyloxymethylic ester of 6- (2- amino- 2- phenylacetamido) penicillanic acid
BG35044A3 (bg) Метод за получаване на 1-окса-бета-лактамови антибиотици