BG36936A3 - Метод за получаване на цефалоспоринови антибиотици - Google Patents

Метод за получаване на цефалоспоринови антибиотици

Info

Publication number
BG36936A3
BG36936A3 BG055737A BG5573782A BG36936A3 BG 36936 A3 BG36936 A3 BG 36936A3 BG 055737 A BG055737 A BG 055737A BG 5573782 A BG5573782 A BG 5573782A BG 36936 A3 BG36936 A3 BG 36936A3
Authority
BG
Bulgaria
Prior art keywords
cephalosporin antibiotics
obtaining
obtaining cephalosporin
antibiotics
proven
Prior art date
Application number
BG055737A
Other languages
Bulgarian (bg)
English (en)
Inventor
William Lunn
John Shakle
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG36936A3 publication Critical patent/BG36936A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG055737A 1981-03-11 1982-03-10 Метод за получаване на цефалоспоринови антибиотици BG36936A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/242,792 US4336253A (en) 1981-03-11 1981-03-11 Cephalosporin antibiotics

Publications (1)

Publication Number Publication Date
BG36936A3 true BG36936A3 (bg) 1985-02-15

Family

ID=22916202

Family Applications (1)

Application Number Title Priority Date Filing Date
BG055737A BG36936A3 (bg) 1981-03-11 1982-03-10 Метод за получаване на цефалоспоринови антибиотици

Country Status (21)

Country Link
US (1) US4336253A (de)
EP (1) EP0060144A3 (de)
JP (1) JPS57165393A (de)
KR (1) KR830009119A (de)
AU (1) AU8091182A (de)
BG (1) BG36936A3 (de)
CA (1) CA1177066A (de)
CS (1) CS238620B2 (de)
DD (1) DD201599A5 (de)
DK (1) DK100982A (de)
ES (1) ES510307A0 (de)
FI (1) FI820806A7 (de)
GB (1) GB2094309B (de)
GR (1) GR74714B (de)
IL (1) IL65185A0 (de)
NZ (1) NZ199959A (de)
PH (1) PH17022A (de)
PL (1) PL130568B1 (de)
PT (1) PT74558B (de)
RO (1) RO82962B (de)
ZA (1) ZA821525B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4450270A (en) * 1981-10-02 1984-05-22 Eli Lilly And Company Dioximino cephalosporin antibiotics
US4616081A (en) * 1982-07-07 1986-10-07 Asahi Kasei Kogyo Kabushiki Kaisha Cephalosporin compounds
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
ATE177104T1 (de) * 1984-11-23 1999-03-15 Biochemie Gmbh Cephalosporinderivative
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4749522A (en) * 1985-10-31 1988-06-07 Angio-Medical Corporation Supercritical fluid extraction of animal derived materials
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US7847093B2 (en) * 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime
EP1618114B1 (de) 2003-04-16 2010-07-14 Sandoz AG Verfahren zur herstellung von cefepim
WO2006008749A1 (en) * 2004-07-16 2006-01-26 Hetero Drugs Limited Process for preparing pure cephalosporine intermediates
PT3616695T (pt) 2011-09-09 2024-11-18 Merck Sharp & Dohme Ceftolozano/tazobactam para tratar infeções intrapulmonares
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274996A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Tazobactam and ceftolozane antibiotic compositions
PE20160048A1 (es) 2013-03-15 2016-02-12 Merck Sharp & Dohme Composiciones antibioticas de ceftolozano
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3792047A (en) * 1971-12-07 1974-02-12 Glaxo Lab Ltd N-(7,2'-thienylacetamidoceph-3-em-3-ylmethyl)-3"or 4"-n-hydroxyloweralkylcarbamoyl-pyridinium-4-carboxylates
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS52125188A (en) 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
GB2027692B (en) 1978-05-26 1983-02-09 Glaxo Group Ltd Cephalosporin antibiotics
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
ZA792581B (en) 1978-05-26 1981-01-28 Glaxo Group Ltd Cephalosporin antibiotics
NL8001087A (nl) 1979-02-23 1980-08-26 Glaxo Group Ltd Cefalosporine antibiotica.
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Also Published As

Publication number Publication date
NZ199959A (en) 1985-08-16
FI820806L (fi) 1982-09-12
ES8303426A1 (es) 1983-02-01
US4336253A (en) 1982-06-22
RO82962B (ro) 1984-01-30
KR830009119A (ko) 1983-12-17
ES510307A0 (es) 1983-02-01
AU8091182A (en) 1982-09-16
CA1177066A (en) 1984-10-30
IL65185A0 (en) 1982-05-31
CS238620B2 (en) 1985-12-16
PL235396A1 (de) 1982-09-27
PT74558A (en) 1982-04-01
GB2094309B (en) 1985-03-27
FI820806A7 (fi) 1982-09-12
PT74558B (en) 1984-11-27
EP0060144A2 (de) 1982-09-15
EP0060144A3 (de) 1983-09-14
DD201599A5 (de) 1983-07-27
PL130568B1 (en) 1984-08-31
RO82962A (ro) 1984-01-14
GB2094309A (en) 1982-09-15
ZA821525B (en) 1983-03-30
JPS57165393A (en) 1982-10-12
PH17022A (en) 1984-05-11
GR74714B (de) 1984-07-06
DK100982A (da) 1982-09-12

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