BG49761A1 - 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation - Google Patents

4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Info

Publication number
BG49761A1
BG49761A1 BG8822089A BG8822089A BG49761A1 BG 49761 A1 BG49761 A1 BG 49761A1 BG 8822089 A BG8822089 A BG 8822089A BG 8822089 A BG8822089 A BG 8822089A BG 49761 A1 BG49761 A1 BG 49761A1
Authority
BG
Bulgaria
Prior art keywords
tetrahydroisohinolines
chalophenyl
methyl
preparation
Prior art date
Application number
BG8822089A
Other languages
English (en)
Inventor
Nedjalka S Ivanova
Donka M Mondeshka
Chavdar B Ivanov
Ivanka G Angelova
Stefan E Bojadzhiev
Chonka N Tancheva
Spaska A Terzijska
Mariana R Tosheva
Vladimir A Parashikov
Vladimir D Paskov
Veselin A Velkov
Original Assignee
Vissh Khim T I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vissh Khim T I filed Critical Vissh Khim T I
Priority to BG8822089A priority Critical patent/BG49761A1/xx
Priority to EP90107538A priority patent/EP0400319A1/fr
Priority to CA 2015114 priority patent/CA2015114A1/fr
Priority to AU53810/90A priority patent/AU5381090A/en
Priority to PL28491190A priority patent/PL284911A1/xx
Publication of BG49761A1 publication Critical patent/BG49761A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG8822089A 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation BG49761A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation
EP90107538A EP0400319A1 (fr) 1989-04-24 1990-04-20 4-(4'-halophényl)-2-méthyl-1,2,3,4-tétrahydroisoquinoléines et procédé pour leur préparation
CA 2015114 CA2015114A1 (fr) 1989-04-24 1990-04-23 4-(4'-halophenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolines et methode de preparation
AU53810/90A AU5381090A (en) 1989-04-24 1990-04-24 4-(-4'-halophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolines and a method for their preparation
PL28491190A PL284911A1 (en) 1989-04-24 1990-04-24 Method of obtaining novel 4-/4'-halogenophenyl/-2-methyl-1,2,3,4-tetrahydroisoquinolines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Publications (1)

Publication Number Publication Date
BG49761A1 true BG49761A1 (en) 1992-02-14

Family

ID=3921819

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Country Status (5)

Country Link
EP (1) EP0400319A1 (fr)
AU (1) AU5381090A (fr)
BG (1) BG49761A1 (fr)
CA (1) CA2015114A1 (fr)
PL (1) PL284911A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
DK1246806T3 (da) * 1999-11-03 2008-06-16 Amr Technology Inc Aryl- og heteroarylsubstituerede tetrahydroisoquinoliner og anvendelse deraf til blokering af genoptagelse af norepinefrin, dopsmin og serotonin
MXPA03000275A (es) * 2000-07-11 2004-12-13 Albany Molecular Res Inc Nuevas tetrahidroisoquinolinas substituidas con 4-fenilo y su uso terapeutico.
UA91341C2 (ru) 2004-07-15 2010-07-26 Амр Текнолоджи, Інк. Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина
CN101128432A (zh) * 2004-12-17 2008-02-20 詹森药业有限公司 用于治疗中枢神经系统疾病的四氢异喹啉化合物
US7956050B2 (en) 2005-07-15 2011-06-07 Albany Molecular Research, Inc. Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
JP5739415B2 (ja) 2009-05-12 2015-06-24 ブリストル−マイヤーズ スクウィブ カンパニー （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用
CN102595902B (zh) 2009-05-12 2015-04-29 阿尔巴尼分子研究公司 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso

Also Published As

Publication number Publication date
EP0400319A1 (fr) 1990-12-05
PL284911A1 (en) 1991-11-04
AU5381090A (en) 1990-10-25
CA2015114A1 (fr) 1990-10-24

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