BG64039B1 - Дозофиксиращ инхалатор за флутиказонпропионат - Google Patents

Дозофиксиращ инхалатор за флутиказонпропионат Download PDF

Info

Publication number: BG64039B1
Authority: BG; Bulgaria
Prior art keywords: inhaler according; fluorocarbon; dosage form; combination; fluticasone propionate
Prior art date: 1995-04-14

Application number

BG101972A

Other languages

Bulgarian (bg)

English (en)

Other versions

BG101972A (bg

Inventor

Ian ASHURST

Craig HERMAN

Li Li-Bovet

Michael RIEBE

Original Assignee

Glaxo Wellcome Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-14

Filing date

1997-10-15

Publication date

2003-11-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27025486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG64039(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-10-15 Application filed by Glaxo Wellcome Inc. filed Critical Glaxo Wellcome Inc.

1998-04-30 Publication of BG101972A publication Critical patent/BG101972A/xx

2003-11-28 Publication of BG64039B1 publication Critical patent/BG64039B1/bg

Links

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239000013543 active substance Substances 0.000 claims abstract description 10
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229960000289 fluticasone propionate Drugs 0.000 claims description 38
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QHSJIZLJUFMIFP-UHFFFAOYSA-N ethene;1,1,2,2-tetrafluoroethene Chemical compound C=C.FC(F)=C(F)F QHSJIZLJUFMIFP-UHFFFAOYSA-N 0.000 description 1
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 1
229960001022 fenoterol Drugs 0.000 description 1
239000003337 fertilizer Substances 0.000 description 1
239000007888 film coating Substances 0.000 description 1
238000009501 film coating Methods 0.000 description 1
239000010419 fine particle Substances 0.000 description 1
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229960000676 flunisolide Drugs 0.000 description 1
229910052731 fluorine Inorganic materials 0.000 description 1
239000011737 fluorine Substances 0.000 description 1
125000001153 fluoro group Chemical group F* 0.000 description 1
239000004811 fluoropolymer Substances 0.000 description 1
229960002714 fluticasone Drugs 0.000 description 1
MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 description 1
229960002848 formoterol Drugs 0.000 description 1
BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 1
239000007789 gas Substances 0.000 description 1
239000011521 glass Substances 0.000 description 1
MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 1
229960004666 glucagon Drugs 0.000 description 1
229910052736 halogen Inorganic materials 0.000 description 1
150000002367 halogens Chemical group 0.000 description 1
125000003104 hexanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
229920001519 homopolymer Polymers 0.000 description 1
229940088597 hormone Drugs 0.000 description 1
239000005556 hormone Substances 0.000 description 1
150000004677 hydrates Chemical class 0.000 description 1
150000002430 hydrocarbons Chemical group 0.000 description 1
OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
229960000890 hydrocortisone Drugs 0.000 description 1
150000005828 hydrofluoroalkanes Chemical class 0.000 description 1
125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
239000012678 infectious agent Substances 0.000 description 1
238000002664 inhalation therapy Methods 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
229940125396 insulin Drugs 0.000 description 1
OEXHQOGQTVQTAT-JRNQLAHRSA-N ipratropium Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 OEXHQOGQTVQTAT-JRNQLAHRSA-N 0.000 description 1
229960001888 ipratropium Drugs 0.000 description 1
239000002085 irritant Substances 0.000 description 1
231100000021 irritant Toxicity 0.000 description 1
229960001317 isoprenaline Drugs 0.000 description 1
229960004958 ketotifen Drugs 0.000 description 1
231100001231 less toxic Toxicity 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
LMOINURANNBYCM-UHFFFAOYSA-N metaproterenol Chemical compound CC(C)NCC(O)C1=CC(O)=CC(O)=C1 LMOINURANNBYCM-UHFFFAOYSA-N 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
230000003278 mimic effect Effects 0.000 description 1
230000004048 modification Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
229960005181 morphine Drugs 0.000 description 1
210000003928 nasal cavity Anatomy 0.000 description 1
229960004398 nedocromil Drugs 0.000 description 1
RQTOOFIXOKYGAN-UHFFFAOYSA-N nedocromil Chemical compound CCN1C(C(O)=O)=CC(=O)C2=C1C(CCC)=C1OC(C(O)=O)=CC(=O)C1=C2 RQTOOFIXOKYGAN-UHFFFAOYSA-N 0.000 description 1
229920006120 non-fluorinated polymer Polymers 0.000 description 1
239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
230000009965 odorless effect Effects 0.000 description 1
229960002657 orciprenaline Drugs 0.000 description 1
RLANKEDHRWMNRO-UHFFFAOYSA-M oxtriphylline Chemical compound C[N+](C)(C)CCO.O=C1N(C)C(=O)N(C)C2=C1[N-]C=N2 RLANKEDHRWMNRO-UHFFFAOYSA-M 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
150000002960 penicillins Chemical class 0.000 description 1
XDRYMKDFEDOLFX-UHFFFAOYSA-N pentamidine Chemical compound C1=CC(C(=N)N)=CC=C1OCCCCCOC1=CC=C(C(N)=N)C=C1 XDRYMKDFEDOLFX-UHFFFAOYSA-N 0.000 description 1
229960004448 pentamidine Drugs 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 description 1
229960000395 phenylpropanolamine Drugs 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
239000002798 polar solvent Substances 0.000 description 1
229920000515 polycarbonate Polymers 0.000 description 1
239000004417 polycarbonate Substances 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
229920001721 polyimide Polymers 0.000 description 1
229920005862 polyol Polymers 0.000 description 1
150000003077 polyols Chemical class 0.000 description 1
229920006324 polyoxymethylene Polymers 0.000 description 1
229920006389 polyphenyl polymer Polymers 0.000 description 1
229920002635 polyurethane Polymers 0.000 description 1
239000004814 polyurethane Substances 0.000 description 1
229940098458 powder spray Drugs 0.000 description 1
229960005205 prednisolone Drugs 0.000 description 1
OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 1
229960002720 reproterol Drugs 0.000 description 1
WVLAAKXASPCBGT-UHFFFAOYSA-N reproterol Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC(O)C1=CC(O)=CC(O)=C1 WVLAAKXASPCBGT-UHFFFAOYSA-N 0.000 description 1
IYMMESGOJVNCKV-SKDRFNHKSA-N rimiterol Chemical compound C([C@@H]1[C@@H](O)C=2C=C(O)C(O)=CC=2)CCCN1 IYMMESGOJVNCKV-SKDRFNHKSA-N 0.000 description 1
229960001457 rimiterol Drugs 0.000 description 1
238000007761 roller coating Methods 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000002002 slurry Substances 0.000 description 1
239000012453 solvate Substances 0.000 description 1
238000003860 storage Methods 0.000 description 1
150000004763 sulfides Chemical class 0.000 description 1
229940124530 sulfonamide Drugs 0.000 description 1
150000003456 sulfonamides Chemical class 0.000 description 1
229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 description 1
230000009967 tasteless effect Effects 0.000 description 1
235000019364 tetracycline Nutrition 0.000 description 1
150000003522 tetracyclines Chemical class 0.000 description 1
229940040944 tetracyclines Drugs 0.000 description 1
229910052716 thallium Inorganic materials 0.000 description 1
BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 description 1
229960000278 theophylline Drugs 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
239000005028 tinplate Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
- B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
- B65D83/52—Metering valves; Metering devices
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0222—Materials for reducing friction

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Mechanical Engineering (AREA)
Dispersion Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Steroid Compounds (AREA)

BG101972A 1995-04-14 1997-10-15 Дозофиксиращ инхалатор за флутиказонпропионат BG64039B1 (bg)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US42211195A	1995-04-14	1995-04-14
US58485996A	1996-01-05	1996-01-05
PCT/US1996/005006 WO1996032151A1 (en)	1995-04-14	1996-04-10	Metered dose inhaler for fluticasone propionate

Publications (2)

Publication Number	Publication Date
BG101972A BG101972A (bg)	1998-04-30
BG64039B1 true BG64039B1 (bg)	2003-11-28

Family

ID=27025486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG101972A BG64039B1 (bg)	1995-04-14	1997-10-15	Дозофиксиращ инхалатор за флутиказонпропионат

Country Status (31)

Country	Link
US (4)	US6253762B1 (de)
EP (4)	EP1166811B1 (de)
JP (2)	JPH11503352A (de)
KR (1)	KR100394299B1 (de)
CN (1)	CN1113675C (de)
AP (1)	AP960A (de)
AT (2)	ATE347391T1 (de)
AU (2)	AU718576B2 (de)
BG (1)	BG64039B1 (de)
BR (1)	BR9604978A (de)
CA (1)	CA2217948C (de)
CY (1)	CY2401B1 (de)
CZ (1)	CZ296256B6 (de)
DE (2)	DE69622269T2 (de)
DK (2)	DK0820322T3 (de)
EA (1)	EA000891B1 (de)
EE (1)	EE04004B1 (de)
ES (2)	ES2179190T3 (de)
HU (1)	HU219899B (de)
IS (1)	IS4571A (de)
MX (1)	MX9707862A (de)
NO (1)	NO974735L (de)
NZ (1)	NZ305787A (de)
OA (1)	OA10624A (de)
PL (1)	PL180895B1 (de)
PT (2)	PT1166811E (de)
RO (1)	RO119117B1 (de)
SK (1)	SK284448B6 (de)
TR (1)	TR199701168T1 (de)
UA (1)	UA51649C2 (de)
WO (1)	WO1996032151A1 (de)

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EP1263491A2 (de) *	2000-03-01	2002-12-11	Glaxo Group Limited	Dosierbarer inhalator
WO2001064275A1 (en) *	2000-03-01	2001-09-07	Glaxo Group Limited	Metered dose inhaler
US20030026766A1 (en) *	2000-04-13	2003-02-06	Mark Sanders	Medicaments for treating respiratory disorders comprising formoterol and fluticasone
IT1318514B1 (it) *	2000-05-12	2003-08-27	Chiesi Farma Spa	Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
AU2001264594A1 (en) *	2000-05-15	2001-11-26	Glaxo Group Limited	Aerosol mdi overcap containing desiccant
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US6455028B1 (en)	2001-04-23	2002-09-24	Pharmascience	Ipratropium formulation for pulmonary inhalation
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TR200401980T4 (tr)	2001-07-02	2004-09-21	Chiesi Farmaceutici S.P.A.	Aerosol olarak uygulama için en uygun hale getirilmiş tobramisin formülasyonu
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ES2342463T3 (es) *	2002-03-01	2010-07-07	Chiesi Farmaceutici S.P.A.	Formulacion superfina de formoterol.
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1996
- 1996-04-10 HU HU9802278A patent/HU219899B/hu unknown
- 1996-04-10 PT PT01122359T patent/PT1166811E/pt unknown
- 1996-04-10 PL PL96322770A patent/PL180895B1/pl unknown
- 1996-04-10 EP EP01122359A patent/EP1166811B1/de not_active Revoked
- 1996-04-10 EP EP96910810A patent/EP0820322B1/de not_active Revoked
- 1996-04-10 KR KR1019970707249A patent/KR100394299B1/ko not_active Expired - Lifetime
- 1996-04-10 DE DE69622269T patent/DE69622269T2/de not_active Revoked
- 1996-04-10 AT AT01122359T patent/ATE347391T1/de not_active IP Right Cessation
- 1996-04-10 CN CN96194635A patent/CN1113675C/zh not_active Expired - Lifetime
- 1996-04-10 EA EA199700232A patent/EA000891B1/ru not_active IP Right Cessation
- 1996-04-10 PT PT96910810T patent/PT820322E/pt unknown
- 1996-04-10 DK DK96910810T patent/DK0820322T3/da active
- 1996-04-10 RO RO97-01882A patent/RO119117B1/ro unknown
- 1996-04-10 TR TR97/01168T patent/TR199701168T1/xx unknown
- 1996-04-10 JP JP8531180A patent/JPH11503352A/ja active Pending
- 1996-04-10 SK SK1390-97A patent/SK284448B6/sk not_active IP Right Cessation
- 1996-04-10 EP EP06023318.6A patent/EP1769819A3/de not_active Withdrawn
- 1996-04-10 CA CA002217948A patent/CA2217948C/en not_active Expired - Lifetime
- 1996-04-10 AU AU53901/96A patent/AU718576B2/en not_active Expired
- 1996-04-10 NZ NZ305787A patent/NZ305787A/xx not_active IP Right Cessation
- 1996-04-10 CZ CZ0325897A patent/CZ296256B6/cs not_active IP Right Cessation
- 1996-04-10 MX MX9707862A patent/MX9707862A/es unknown
- 1996-04-10 EP EP00128067A patent/EP1084726A3/de not_active Ceased
- 1996-04-10 BR BR9604978-2A patent/BR9604978A/pt not_active IP Right Cessation
- 1996-04-10 WO PCT/US1996/005006 patent/WO1996032151A1/en not_active Ceased
- 1996-04-10 AP APAP/P/1997/001111A patent/AP960A/en active
- 1996-04-10 AT AT96910810T patent/ATE220338T1/de not_active IP Right Cessation
- 1996-04-10 ES ES96910810T patent/ES2179190T3/es not_active Expired - Lifetime
- 1996-04-10 DK DK01122359T patent/DK1166811T3/da active
- 1996-04-10 ES ES01122359T patent/ES2276736T3/es not_active Expired - Lifetime
- 1996-04-10 DE DE69636757T patent/DE69636757T2/de not_active Revoked
- 1996-04-10 EE EE9700285A patent/EE04004B1/xx unknown
- 1996-10-04 UA UA97104952A patent/UA51649C2/uk unknown
1997
- 1997-03-31 US US08/829,562 patent/US6253762B1/en not_active Expired - Fee Related
- 1997-09-30 IS IS4571A patent/IS4571A/is unknown
- 1997-10-10 OA OA70102A patent/OA10624A/en unknown
- 1997-10-13 NO NO19974735A patent/NO974735L/no not_active Application Discontinuation
- 1997-10-15 BG BG101972A patent/BG64039B1/bg unknown
2000
- 2000-05-15 US US09/570,725 patent/US6546928B1/en not_active Expired - Fee Related
- 2000-07-11 AU AU45169/00A patent/AU755977B2/en not_active Expired
2001
- 2001-01-18 JP JP2001010020A patent/JP2001231861A/ja active Pending
2003
- 2003-02-03 US US10/356,591 patent/US20030138559A1/en not_active Abandoned
2004
- 2004-01-02 CY CY0400001A patent/CY2401B1/xx unknown
- 2004-04-14 US US10/823,533 patent/US20040187865A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK1166811T3 (da)	2007-03-12
ES2179190T3 (es)	2003-01-16
AU4516900A (en)	2000-09-07
EE04004B1 (et)	2003-04-15
BR9604978A (pt)	1998-06-09
EE9700285A (et)	1998-04-15
CZ325897A3 (cs)	1998-03-18
KR19980703849A (ko)	1998-12-05
EP1084726A3 (de)	2003-06-04
ES2276736T3 (es)	2007-07-01
EP1769819A2 (de)	2007-04-04
NO974735D0 (no)	1997-10-13
AU718576B2 (en)	2000-04-13
US6546928B1 (en)	2003-04-15
EP1166811A2 (de)	2002-01-02
SK139097A3 (en)	1998-05-06
CA2217948A1 (en)	1996-10-17
PT1166811E (pt)	2007-02-28
JPH11503352A (ja)	1999-03-26
BG101972A (bg)	1998-04-30
AP9701111A0 (en)	1997-10-31
MX9707862A (es)	1997-11-29
US6253762B1 (en)	2001-07-03
PT820322E (pt)	2002-10-31
ATE220338T1 (de)	2002-07-15
EA000891B1 (ru)	2000-06-26
CZ296256B6 (cs)	2006-02-15
WO1996032151A1 (en)	1996-10-17
OA10624A (en)	2001-03-15
EA199700232A1 (ru)	1998-02-26
EP1084726A2 (de)	2001-03-21
DK0820322T3 (da)	2002-10-07
DE69636757D1 (de)	2007-01-18
US20040187865A1 (en)	2004-09-30
DE69622269D1 (de)	2002-08-14
HUP9802278A2 (hu)	1999-01-28
TR199701168T1 (xx)	1998-05-21
RO119117B1 (ro)	2004-04-30
AU5390196A (en)	1996-10-30
PL180895B1 (pl)	2001-04-30
NO974735L (no)	1997-12-11
EP1166811A3 (de)	2003-05-28
IS4571A (is)	1997-09-30
CA2217948C (en)	2002-02-19
HU219899B (hu)	2001-09-28
DE69622269T2 (de)	2003-03-06
PL322770A1 (en)	1998-02-16
SK284448B6 (sk)	2005-04-01
AP960A (en)	2001-04-20
ATE347391T1 (de)	2006-12-15
US20030138559A1 (en)	2003-07-24
CN1187138A (zh)	1998-07-08
EP0820322B1 (de)	2002-07-10
DE69636757T2 (de)	2007-10-11
EP1166811B1 (de)	2006-12-06
JP2001231861A (ja)	2001-08-28
CY2401B1 (en)	2004-09-10
HUP9802278A3 (en)	1999-04-28
HK1009406A1 (en)	1999-09-17
EP1769819A3 (de)	2013-05-22
CN1113675C (zh)	2003-07-09
AU755977B2 (en)	2003-01-02
NZ305787A (en)	1999-07-29
UA51649C2 (uk)	2002-12-16
EP0820322A1 (de)	1998-01-28
KR100394299B1 (ko)	2003-10-22

Publication	Publication Date	Title
BG64039B1 (bg)	2003-11-28	Дозофиксиращ инхалатор за флутиказонпропионат
EP0820414B1 (de)	2004-02-04	Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat
KR100403899B1 (ko)	2004-03-20	살메테롤용정량흡입기
BG64075B1 (bg)	2003-12-31	Дозиращ инхалатор за албутерол
US20050002869A1 (en)	2005-01-06	Metered dose inhaler having internal surfaces coated with fluorocarbon polymer
CA2447517C (en)	2006-11-14	Metered dose inhaler for fluticasone propionate
MXPA97007878A (en)	1998-07-03	Inhaler of measured dose for dipropionate of beclometasone
CA2467462A1 (en)	1996-10-17	Metered dose inhaler for salmeterol