BG64457B1 - Фармацевтична форма за орално приложение, съдържаща hiv протеазен инхибитор - Google Patents

Фармацевтична форма за орално приложение, съдържаща hiv протеазен инхибитор Download PDF

Info

Publication number: BG64457B1
Authority: BG; Bulgaria
Prior art keywords: water; compound; tpgs; formula; formulation
Prior art date: 1996-03-22

Application number

BG102838A

Other languages

Bulgarian (bg)

English (en)

Other versions

BG102838A (en

Inventor

Arup Roy

Lloyd Tillman

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-22

Filing date

1998-10-12

Publication date

2005-03-31

1996-03-26 Priority claimed from GBGB9606372.2A external-priority patent/GB9606372D0/en

1998-10-12 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

1999-09-30 Publication of BG102838A publication Critical patent/BG102838A/xx

2005-03-31 Publication of BG64457B1 publication Critical patent/BG64457B1/bg

Links

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229960002555 zidovudine Drugs 0.000 description 1
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BG102838A 1996-03-22 1998-10-12 Фармацевтична форма за орално приложение, съдържаща hiv протеазен инхибитор BG64457B1 (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1389396P	1996-03-22	1996-03-22
GBGB9606372.2A GB9606372D0 (en)	1996-03-26	1996-03-26	Pharmaceutical formulations

Publications (2)

Publication Number	Publication Date
BG102838A BG102838A (en)	1999-09-30
BG64457B1 true BG64457B1 (bg)	2005-03-31

Family

ID=26308992

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG102838A BG64457B1 (bg)	1996-03-22	1998-10-12	Фармацевтична форма за орално приложение, съдържаща hiv протеазен инхибитор

Country Status (12)

Country	Link
JP (1)	JP3117726B2 (pl)
AR (1)	AR006345A1 (pl)
BG (1)	BG64457B1 (pl)
CO (1)	CO4790151A1 (pl)
HU (1)	HU228026B1 (pl)
ID (1)	ID16781A (pl)
IL (1)	IL126185A (pl)
MY (1)	MY126358A (pl)
OA (1)	OA10880A (pl)
PL (1)	PL187919B1 (pl)
TW (1)	TW455491B (pl)
WO (1)	WO1997035587A1 (pl)

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JP2001523221A (ja) *	1996-09-01	2001-11-20	ファーモスコーポレイション	親油性物質の促進された生物学的利用能のための固形共沈物
WO1998057648A1 (en) *	1997-06-16	1998-12-23	Vertex Pharmaceuticals Incorporated	Methods of increasing the bioavailability of stable crystal polymorphs of a compound
US5891845A (en) *	1997-11-21	1999-04-06	Fuisz Technologies Ltd.	Drug delivery systems utilizing liquid crystal structures
ES2140329B1 (es) *	1997-12-04	2000-10-16	Univ Granada	Utilizacion de acido maslinico como inhibidor de proteasas para el tratamiento de la enfermedad causada por los virus de la inmunodeficiencia adquirida.
GB9812189D0 (en) *	1998-06-05	1998-08-05	Glaxo Group Ltd	Methods and compositions for increasing penetration of HIV protease inhibitors
CA2432527A1 (en) *	2000-12-22	2002-07-04	Takeda Chemical Industries, Ltd.	Medicinal compositions for oral use
WO2004050068A1 (en)	2002-11-29	2004-06-17	Janssen Pharmaceutica N.V.	Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
US7423004B2 (en)	2003-01-31	2008-09-09	Smithkline Beecham Corporation	Solid dispersion compositions
WO2006036614A2 (en) *	2004-09-24	2006-04-06	Boehringer Ingelheim Pharmaceuticals, Inc.	A new class of surfactant-like materials comprising vitamin e tpgs and a water soluble polymer
EP1793806A2 (en) *	2004-09-30	2007-06-13	Eastman Chemical Company	Pharmaceutical formulations containing vitamin e tpgs molecules that solubilize lipophilic drugs without significant efflux inhibition, and use of such formulations
EP1880715A1 (en)	2006-07-19	2008-01-23	Abbott GmbH & Co. KG	Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage form containing same
SA109300195B1 (ar)	2008-03-28	2013-04-20	Astrazeneca Ab	تركيبة صيدلانية جديدة مضادة للسرطان
ITRM20120331A1 (it)	2012-07-12	2014-01-13	Guidotti & C Spa Labor	Composizioni pediatriche orali liquide contenenti nepadutant.

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EP0541168A1 (en) *	1991-11-08	1993-05-12	Merck & Co. Inc.	HIV protease inhibitors useful for the treatment of aids
WO1994005639A1 (en) *	1992-09-08	1994-03-17	Vertex Pharmaceuticals Incorporated	Sulfonamide inhibitors of hiv-aspartyl protease
WO1994013629A1 (en) *	1992-12-11	1994-06-23	Vertex Pharmaceuticals Incorporated	Mannitol derivatives and their use as inhibitors of aspartyl protease
WO1994014436A1 (en) *	1992-12-29	1994-07-07	Abbott Laboratories	Retroviral protease inhibiting compounds
WO1994015906A1 (en) *	1993-01-15	1994-07-21	Agouron Pharmaceuticals, Inc.	Hiv protease inhibitors and their preparation
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WO1995012583A1 (en) *	1993-11-05	1995-05-11	Merck & Co., Inc.	New quinazolines as inhibitors of hiv reverse transcriptase
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1997
- 1997-03-20 MY MYPI97001186A patent/MY126358A/en unknown
- 1997-03-21 IL IL12618597A patent/IL126185A/xx not_active IP Right Cessation
- 1997-03-21 WO PCT/EP1997/001438 patent/WO1997035587A1/en not_active Ceased
- 1997-03-21 PL PL32891697A patent/PL187919B1/pl unknown
- 1997-03-21 HU HU9901887A patent/HU228026B1/hu unknown
- 1997-03-21 CO CO97015457A patent/CO4790151A1/es unknown
- 1997-03-21 JP JP09534017A patent/JP3117726B2/ja not_active Expired - Lifetime
- 1997-03-21 TW TW086103607A patent/TW455491B/zh not_active IP Right Cessation
- 1997-03-21 ID IDP970927A patent/ID16781A/id unknown
- 1997-03-21 AR ARP970101146A patent/AR006345A1/es active IP Right Grant
1998
- 1998-09-18 OA OA9800171A patent/OA10880A/en unknown
- 1998-10-12 BG BG102838A patent/BG64457B1/bg unknown

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EP0541168A1 (en) *	1991-11-08	1993-05-12	Merck & Co. Inc.	HIV protease inhibitors useful for the treatment of aids
WO1994005639A1 (en) *	1992-09-08	1994-03-17	Vertex Pharmaceuticals Incorporated	Sulfonamide inhibitors of hiv-aspartyl protease
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WO1995032185A1 (en) *	1994-05-23	1995-11-30	Agouron Pharmaceuticals, Inc.	N-(3-amino-2-hydroxybutyl)sulphonamide derivatives as hiv protease inhibitors

Also Published As

Publication number	Publication date
PL328916A1 (en)	1999-03-01
MY126358A (en)	2006-09-29
OA10880A (en)	2001-10-11
JP3117726B2 (ja)	2000-12-18
WO1997035587A1 (en)	1997-10-02
HU228026B1 (en)	2012-08-28
HUP9901887A2 (hu)	1999-12-28
JP2000500504A (ja)	2000-01-18
AR006345A1 (es)	1999-08-25
IL126185A0 (en)	1999-05-09
ID16781A (id)	1997-11-13
IL126185A (en)	2003-05-29
CO4790151A1 (es)	1999-05-31
HUP9901887A3 (en)	2000-02-28
PL187919B1 (pl)	2004-11-30
BG102838A (en)	1999-09-30
TW455491B (en)	2001-09-21

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