BR0010034A - Utilização de um vetor, processo de preparação de um medicamento útil para a prevenção, a melhoria e/ou o tratamento da hipertensão arterial pulmonar, e, composição farmacêutica - Google Patents
Utilização de um vetor, processo de preparação de um medicamento útil para a prevenção, a melhoria e/ou o tratamento da hipertensão arterial pulmonar, e, composição farmacêuticaInfo
- Publication number
- BR0010034A BR0010034A BR0010034-0A BR0010034A BR0010034A BR 0010034 A BR0010034 A BR 0010034A BR 0010034 A BR0010034 A BR 0010034A BR 0010034 A BR0010034 A BR 0010034A
- Authority
- BR
- Brazil
- Prior art keywords
- vector
- prevention
- treatment
- arterial hypertension
- pulmonary arterial
- Prior art date
Links
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000002870 angiogenesis inducing agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"UTILIZAçãO DE UM VETOR, PROCESSO DE PREPARAçãO DE UM MEDICAMENTO úTIL PARA A PREVENçãO, A MELHORIA E/OU O TRATAMENTO DA HIPERTENSãO ARTERIAL PULMONAR, E, COMPOSIçãO FARMACêUTICA". A presente invenção refere-se à utilização de um vetor compreendendo um ácido nucleico codificando para um fator angiogênico para a prevenção, a melhoria e/ou o tratamento da hipertensão arterial pulmonar.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9905272A FR2792531B1 (fr) | 1999-04-26 | 1999-04-26 | Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire |
| US13973499P | 1999-06-18 | 1999-06-18 | |
| PCT/FR2000/001060 WO2000065043A1 (fr) | 1999-04-26 | 2000-04-21 | Utilisation d'adenovirus recombinant defectif comprenant un acide nucleique codant pour un facteur angiogenique pour le traitement de l'hypertension arterielle pulmonaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0010034A true BR0010034A (pt) | 2002-01-15 |
Family
ID=26234932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0010034-0A BR0010034A (pt) | 1999-04-26 | 2000-04-21 | Utilização de um vetor, processo de preparação de um medicamento útil para a prevenção, a melhoria e/ou o tratamento da hipertensão arterial pulmonar, e, composição farmacêutica |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20020086004A1 (pt) |
| EP (1) | EP1173564A1 (pt) |
| JP (1) | JP2002543097A (pt) |
| KR (1) | KR20020001846A (pt) |
| CN (1) | CN1376197A (pt) |
| AU (1) | AU782833B2 (pt) |
| BR (1) | BR0010034A (pt) |
| CA (1) | CA2370404A1 (pt) |
| CZ (1) | CZ20013813A3 (pt) |
| HU (1) | HUP0200961A3 (pt) |
| IL (1) | IL145834A0 (pt) |
| MX (1) | MXPA01010849A (pt) |
| NO (1) | NO20015223D0 (pt) |
| NZ (1) | NZ515233A (pt) |
| PL (1) | PL351114A1 (pt) |
| SI (1) | SI20750A (pt) |
| WO (1) | WO2000065043A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020072489A1 (en) * | 1998-10-13 | 2002-06-13 | Whitehouse Martha J. | Angiogenically effective unit dose of FGF-2 and method of use |
| US7223724B1 (en) * | 1999-02-08 | 2007-05-29 | Human Genome Sciences, Inc. | Use of vascular endothelial growth factor to treat photoreceptor cells |
| MXPA02003434A (es) * | 2000-08-04 | 2002-09-02 | Human Genome Sciences Inc | Factor de crecimiento endotelial vascular 2. |
| US20050232921A1 (en) * | 2001-04-13 | 2005-10-20 | Rosen Craig A | Vascular endothelial growth factor 2 |
| CA2444632A1 (en) * | 2001-04-13 | 2002-10-24 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| AU2002252631A1 (en) * | 2001-04-13 | 2002-10-28 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| KR100697321B1 (ko) * | 2005-07-27 | 2007-03-20 | 박기랑 | VEGF-A, VEGF-B 및 VEGF-C의 안티센스cDNA를 함유하는 재조합 아데노-연관바이러스(rAAV) 및 이를 함유하는 대장암, 방광암및/또는 폐암 특이적 유전자 치료제 |
| EP2446899B1 (en) * | 2009-06-25 | 2020-09-30 | Bioleaders Corporation | Adjuvant composition comprising (poly-gamma-glutamate)-chitosan nanoparticles |
| CN105833248A (zh) * | 2016-04-27 | 2016-08-10 | 温州医科大学附属第医院 | 成纤维细胞生长因子21的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2717495B1 (fr) * | 1994-03-18 | 1996-04-12 | Rhone Poulenc Rorer Sa | Virus recombinants, préparation et utilisation en thérapie génique. |
| EP0880587A1 (en) * | 1996-02-15 | 1998-12-02 | Chiron Corporation | Gene therapy method using fgf-5 |
| EP0941116B1 (en) * | 1996-11-01 | 2005-01-19 | Ark Therapeutics Limited | Use of vegf for the manufacture of a medicament for the treatment or prevention of intimal hyperplasia and delivery device |
| WO1998037185A2 (en) * | 1997-02-20 | 1998-08-27 | The Board Of Regents Of The University Of Texas System | Vectors for controlled gene expression |
| US6423751B1 (en) * | 1998-07-14 | 2002-07-23 | The Brigham And Women's Hospital, Inc. | Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization |
-
2000
- 2000-04-21 IL IL14583400A patent/IL145834A0/xx unknown
- 2000-04-21 NZ NZ515233A patent/NZ515233A/en unknown
- 2000-04-21 WO PCT/FR2000/001060 patent/WO2000065043A1/fr not_active Ceased
- 2000-04-21 HU HU0200961A patent/HUP0200961A3/hu unknown
- 2000-04-21 EP EP00922713A patent/EP1173564A1/fr not_active Withdrawn
- 2000-04-21 BR BR0010034-0A patent/BR0010034A/pt not_active IP Right Cessation
- 2000-04-21 CZ CZ20013813A patent/CZ20013813A3/cs unknown
- 2000-04-21 CA CA002370404A patent/CA2370404A1/fr not_active Abandoned
- 2000-04-21 PL PL00351114A patent/PL351114A1/xx not_active IP Right Cessation
- 2000-04-21 MX MXPA01010849A patent/MXPA01010849A/es not_active Application Discontinuation
- 2000-04-21 SI SI200020023A patent/SI20750A/sl not_active IP Right Cessation
- 2000-04-21 AU AU43017/00A patent/AU782833B2/en not_active Ceased
- 2000-04-21 CN CN00806521A patent/CN1376197A/zh active Pending
- 2000-04-21 JP JP2000614380A patent/JP2002543097A/ja not_active Withdrawn
- 2000-04-21 KR KR1020017013633A patent/KR20020001846A/ko not_active Withdrawn
-
2001
- 2001-10-25 NO NO20015223A patent/NO20015223D0/no not_active Application Discontinuation
- 2001-10-26 US US09/983,885 patent/US20020086004A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL145834A0 (en) | 2002-07-25 |
| AU782833B2 (en) | 2005-09-01 |
| PL351114A1 (en) | 2003-03-24 |
| HUP0200961A3 (en) | 2004-11-29 |
| SI20750A (sl) | 2002-06-30 |
| CZ20013813A3 (cs) | 2002-02-13 |
| NZ515233A (en) | 2004-08-27 |
| CA2370404A1 (fr) | 2000-11-02 |
| US20020086004A1 (en) | 2002-07-04 |
| NO20015223L (no) | 2001-10-25 |
| EP1173564A1 (fr) | 2002-01-23 |
| HUP0200961A2 (hu) | 2002-07-29 |
| CN1376197A (zh) | 2002-10-23 |
| AU4301700A (en) | 2000-11-10 |
| KR20020001846A (ko) | 2002-01-09 |
| JP2002543097A (ja) | 2002-12-17 |
| MXPA01010849A (es) | 2002-11-07 |
| WO2000065043A1 (fr) | 2000-11-02 |
| NO20015223D0 (no) | 2001-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |
|
| B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1991 DE 03/03/2009 POR TER SIDO INDEVIDO. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A E 9A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2016 DE 25/08/2009. |