BR0010459A - Preparação de lipossoma contendo derivado de ácido pipecólico e preparação sólida - Google Patents

Preparação de lipossoma contendo derivado de ácido pipecólico e preparação sólida

Info

Publication number
BR0010459A
BR0010459A BR0010459-0A BR0010459A BR0010459A BR 0010459 A BR0010459 A BR 0010459A BR 0010459 A BR0010459 A BR 0010459A BR 0010459 A BR0010459 A BR 0010459A
Authority
BR
Brazil
Prior art keywords
preparation
acid derivative
liposome
pipecolic acid
liposome containing
Prior art date
Application number
BR0010459-0A
Other languages
English (en)
Inventor
Jiro Fujisaki
Hajime Konno
Akihiro Kasai
Kazumi Ohtomo
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of BR0010459A publication Critical patent/BR0010459A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

"PREPARAçãO DE LIPOSSOMA CONTENDO DERIVADO DE áCIDO PIPECóLICO E PREPARAçãO SóLIDA". A presente invenção provê uma preparação de lipossoma contendo derivado de ácido pipecólico tendo uma ação rápida excelente para lidar com uma situação de emergência, tal como infarto cerebral. Uma preparação de lipossoma definida por compreender, como ingrediente ativo, um derivado de ácido pipecólico do ingrediente descrito na presente especificação ou um sal farmaceuticamente aceitável do mesmo encapsulado em lipossomas, sendo que lecitina é principalmente utilizada como lipídio formador de lipossoma, e dita preparação de lipossoma não contendo colesterol como estabilizante.
BR0010459-0A 1999-03-11 2000-03-10 Preparação de lipossoma contendo derivado de ácido pipecólico e preparação sólida BR0010459A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6546999 1999-03-11
JP15186699 1999-05-31
PCT/JP2000/001446 WO2000053177A1 (en) 1999-03-11 2000-03-10 Liposome preparations

Publications (1)

Publication Number Publication Date
BR0010459A true BR0010459A (pt) 2002-02-05

Family

ID=26406610

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010459-0A BR0010459A (pt) 1999-03-11 2000-03-10 Preparação de lipossoma contendo derivado de ácido pipecólico e preparação sólida

Country Status (14)

Country Link
US (1) US6984397B2 (pt)
EP (1) EP1159962A4 (pt)
KR (1) KR20010102370A (pt)
CN (1) CN1342075A (pt)
AR (1) AR022915A1 (pt)
AU (1) AU775694B2 (pt)
BR (1) BR0010459A (pt)
CA (1) CA2364257A1 (pt)
CZ (1) CZ20013209A3 (pt)
HU (1) HUP0200483A3 (pt)
IL (1) IL144828A0 (pt)
NZ (1) NZ514046A (pt)
TR (1) TR200102778T2 (pt)
WO (1) WO2000053177A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
JP5815915B2 (ja) * 2005-10-11 2015-11-17 ユニバーシティー オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 過活動膀胱障害の治療のためのスフィンゴミエリンリポソーム
CA2673863A1 (en) * 2006-12-28 2008-07-10 Limerick Biopharma, Inc. Methods and compositions for therapeutic treatment
JP2011500512A (ja) * 2007-07-31 2011-01-06 リメリック バイオファーマ，インコーポレイティド リン酸化ピロン類似体および方法
CA2737025C (en) * 2008-09-27 2012-09-04 Jina Pharmaceuticals, Inc. Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof
CN102579437B (zh) * 2011-01-06 2014-10-29 中国医学科学院医药生物技术研究所 含醇的他克莫司组合物及其制备方法
ES2952675T3 (es) 2013-10-22 2023-11-03 Lipella Pharmaceuticals Inc Administración de agentes mediante el uso de liposomas metaestables
JP7186093B2 (ja) * 2016-04-19 2022-12-08 ナンヤン テクノロジカル ユニヴァーシティー 前眼部疾患の治療のためのタクロリムスの持続送達用ナノリポソーム
US20190216735A1 (en) * 2016-09-14 2019-07-18 Nanyang Technological University Liposomal formulations

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880635B1 (en) 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US5089181A (en) 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
DE68916439T2 (de) 1988-10-05 1994-10-20 Vestar Inc Verfahren zur herstellung von liposomen mit verbesserter stabilität während des trocknens.
US5189042A (en) * 1991-08-22 1993-02-23 Merck & Co. Inc. Fluoromacrolides having immunosuppressive activity
EP0658344B1 (en) * 1991-10-31 2000-01-05 Fujisawa Pharmaceutical Co., Ltd. Liposome preparation containing tricyclic compound
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
JPH09131348A (ja) * 1995-11-07 1997-05-20 Chugoku Kayaku Kk 血管の閉塞治療用及びガン治療用装置
TW426516B (en) * 1996-12-06 2001-03-21 Fujisawa Pharmaceutical Co An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds
US6034135A (en) 1997-03-06 2000-03-07 Promega Biosciences, Inc. Dimeric cationic lipids
JPH1146759A (ja) * 1997-08-06 1999-02-23 Terumo Corp 細胞培養液
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6720001B2 (en) 1999-10-18 2004-04-13 Lipocine, Inc. Emulsion compositions for polyfunctional active ingredients

Also Published As

Publication number Publication date
HUP0200483A3 (en) 2004-07-28
US6984397B2 (en) 2006-01-10
HUP0200483A2 (en) 2002-06-29
TR200102778T2 (tr) 2002-05-21
CN1342075A (zh) 2002-03-27
NZ514046A (en) 2003-10-31
EP1159962A1 (en) 2001-12-05
KR20010102370A (ko) 2001-11-15
CA2364257A1 (en) 2000-09-14
AR022915A1 (es) 2002-09-04
CZ20013209A3 (cs) 2001-12-12
IL144828A0 (en) 2002-06-30
AU775694B2 (en) 2004-08-12
WO2000053177A1 (en) 2000-09-14
EP1159962A4 (en) 2003-07-02
AU2940500A (en) 2000-09-28
US20040028728A1 (en) 2004-02-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.