BR0010517A - Imaging methods of a thrombus, pulmonary embolus, arterial thrombus and coronary thrombus - Google Patents

Imaging methods of a thrombus, pulmonary embolus, arterial thrombus and coronary thrombus

Info

Publication number
BR0010517A
BR0010517A BR0010517-1A BR0010517A BR0010517A BR 0010517 A BR0010517 A BR 0010517A BR 0010517 A BR0010517 A BR 0010517A BR 0010517 A BR0010517 A BR 0010517A
Authority
BR
Brazil
Prior art keywords
thrombus
coronary
arterial
dimensional
line
Prior art date
Application number
BR0010517-1A
Other languages
Portuguese (pt)
Inventor
Joel Lazewatsky
Original Assignee
Du Pont Pharm Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co
Publication of BR0010517A publication Critical patent/BR0010517A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Image Processing (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"MéTODOS DE FORMAçãO DE IMAGEM DE UM TROMBO, DE UM êMBOLO PULMONAR, DE UM TROMBO ARTERIAL E DE UM TROMBO CORONARIANO". Método em que um composto rádio-marcado é localizado em um trombo. Imagens bidimensionais, que representam uma propriedade física associada ao trombo rádio-marcado, são obtidas e montadas em uma matriz tridimensional de dados. A matriz tridimensional de dados é então examinada ao longo de um conjunto de linhas paralelas, para determinar o valor máximo em cada linha. O valor máximo em cada linha recebe então um pixel em um conjunto bidimensional, em que a posição relativa do pixel no conjunto bidimensional corresponde à posição relativa da linha no conjunto de linhas paralelas."METHODS FOR FORMING A THROMBO, A PULMONARY PISTON, AN ARTERIAL THROMBON AND A CORONARY THROMBON". Method in which a radiolabeled compound is located in a thrombus. Two-dimensional images, which represent a physical property associated with the radiolabelled thrombus, are obtained and assembled in a three-dimensional data matrix. The three-dimensional data matrix is then examined over a set of parallel lines, to determine the maximum value on each line. The maximum value in each line then receives a pixel in a two-dimensional set, where the relative position of the pixel in the two-dimensional set corresponds to the relative position of the line in the set of parallel lines.

BR0010517-1A 1999-03-26 2000-03-24 Imaging methods of a thrombus, pulmonary embolus, arterial thrombus and coronary thrombus BR0010517A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12635999P 1999-03-26 1999-03-26
PCT/US2000/007891 WO2000057787A2 (en) 1999-03-26 2000-03-24 Method for localization of blood clots

Publications (1)

Publication Number Publication Date
BR0010517A true BR0010517A (en) 2002-01-08

Family

ID=22424397

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0010517-1A BR0010517A (en) 1999-03-26 2000-03-24 Imaging methods of a thrombus, pulmonary embolus, arterial thrombus and coronary thrombus

Country Status (5)

Country Link
AU (1) AU4027800A (en)
BR (1) BR0010517A (en)
CA (1) CA2364753A1 (en)
IL (1) IL145130A0 (en)
WO (1) WO2000057787A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals

Also Published As

Publication number Publication date
CA2364753A1 (en) 2000-10-05
WO2000057787A2 (en) 2000-10-05
IL145130A0 (en) 2002-06-30
WO2000057787A3 (en) 2001-02-22
AU4027800A (en) 2000-10-16

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]