BR0012042A - Compostos, processo para a preparação dos mesmos, composições farmacêuticas, e, utilização dos compostos - Google Patents

Compostos, processo para a preparação dos mesmos, composições farmacêuticas, e, utilização dos compostos

Info

Publication number
BR0012042A
BR0012042A BR0012042-1A BR0012042A BR0012042A BR 0012042 A BR0012042 A BR 0012042A BR 0012042 A BR0012042 A BR 0012042A BR 0012042 A BR0012042 A BR 0012042A
Authority
BR
Brazil
Prior art keywords
compounds
preparation
pharmaceutical compositions
dextrogyrous
levogyrous
Prior art date
Application number
BR0012042-1A
Other languages
English (en)
Inventor
Thierry Imbert
Patrice Mayer
Marc Marien
Peters Pauwels
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of BR0012042A publication Critical patent/BR0012042A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

"COMPOSTOS, PROCESSO PARA A PREPARAçãO DOS MESMOS, COMPOSIçõES FARMACêUTICAS, E, UTILIZAçãO DOS COMPOSTOS". A presente invenção refere-se a novos derivados benzodioxano imidazolinas fluorados, sua preparação e suas aplicações em terapêutica. A invenção visa mais particularmente aos compostos correspondendo à estrutura da fórmula geral (1) em que R representa um grupo alquila, ou alcenila, linear, ramificado ou cíclico, compreendendo 1 a 7 átomos de carbono ou um grupo benzila, e o átomo de fluor pode ocupar a posição 5, 6, 7 ou 8, sob sua forma racêmica e suas formas enantiomericamente puras, dextrogiros e levogiros, assim como seus sais de adição.
BR0012042-1A 1999-06-29 2000-06-29 Compostos, processo para a preparação dos mesmos, composições farmacêuticas, e, utilização dos compostos BR0012042A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9908302A FR2795727B1 (fr) 1999-06-29 1999-06-29 Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique
PCT/FR2000/001825 WO2001000619A1 (fr) 1999-06-29 2000-06-29 Nouveaux derives benzodioxanne imidazolines fluores, leur preparation et leurs applications en therapeutique

Publications (1)

Publication Number Publication Date
BR0012042A true BR0012042A (pt) 2002-07-09

Family

ID=9547432

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012042-1A BR0012042A (pt) 1999-06-29 2000-06-29 Compostos, processo para a preparação dos mesmos, composições farmacêuticas, e, utilização dos compostos

Country Status (16)

Country Link
US (1) US6610725B1 (pt)
EP (1) EP1192152B1 (pt)
JP (1) JP4608160B2 (pt)
CN (1) CN1139588C (pt)
AT (1) ATE228516T1 (pt)
AU (1) AU778796B2 (pt)
BR (1) BR0012042A (pt)
CA (1) CA2377186A1 (pt)
DE (1) DE60000880T2 (pt)
DK (1) DK1192152T3 (pt)
ES (1) ES2186654T3 (pt)
FR (1) FR2795727B1 (pt)
MX (1) MXPA02000256A (pt)
PT (1) PT1192152E (pt)
WO (1) WO2001000619A1 (pt)
ZA (1) ZA200200009B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117645D0 (en) * 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
JP4604583B2 (ja) * 2004-07-20 2011-01-05 ダイソー株式会社 １−アミド−３−（２−ヒドロキシフェノキシ）−２−プロパノール誘導体、ならびに２−アミドメチル−１，４−ベンゾジオキサン誘導体の製造法
US8580776B2 (en) * 2007-07-10 2013-11-12 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating neurodegenerating diseases
US20110165037A1 (en) * 2010-01-07 2011-07-07 Ismagilov Rustem F Interfaces that eliminate non-specific adsorption, and introduce specific interactions
MX2018015872A (es) * 2016-06-29 2019-04-22 Orion Corp Derivados de benzodioxano y su uso farmaceutico.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
NZ203680A (en) * 1982-04-17 1985-08-16 Reckitt & Colmann Prod Ltd Imidazolines and pharmaceutical compositions

Also Published As

Publication number Publication date
JP2003503406A (ja) 2003-01-28
AU6289000A (en) 2001-01-31
DE60000880D1 (de) 2003-01-09
EP1192152B1 (fr) 2002-11-27
EP1192152A1 (fr) 2002-04-03
WO2001000619A1 (fr) 2001-01-04
CN1361776A (zh) 2002-07-31
DK1192152T3 (da) 2003-03-17
MXPA02000256A (es) 2002-06-21
ES2186654T3 (es) 2003-05-16
CN1139588C (zh) 2004-02-25
US6610725B1 (en) 2003-08-26
CA2377186A1 (fr) 2001-01-04
PT1192152E (pt) 2003-04-30
FR2795727A1 (fr) 2001-01-05
JP4608160B2 (ja) 2011-01-05
AU778796B2 (en) 2004-12-23
FR2795727B1 (fr) 2001-09-21
ATE228516T1 (de) 2002-12-15
DE60000880T2 (de) 2003-08-28
ZA200200009B (en) 2002-09-25

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements