BR0012121A - Derivado de aminotetralina para terapia de doenças cardiovasculares - Google Patents

Derivado de aminotetralina para terapia de doenças cardiovasculares

Info

Publication number
BR0012121A
BR0012121A BR0012121-5A BR0012121A BR0012121A BR 0012121 A BR0012121 A BR 0012121A BR 0012121 A BR0012121 A BR 0012121A BR 0012121 A BR0012121 A BR 0012121A
Authority
BR
Brazil
Prior art keywords
cardiovascular disease
disease therapy
aminotetralin
left ventricular
derivative
Prior art date
Application number
BR0012121-5A
Other languages
English (en)
Inventor
Stefano Bongrani
Paolo Chiesi
Roberta Razzetti
Maurizio Civelli
Alberto Umile
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/328,434 external-priority patent/US6103760A/en
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Priority claimed from PCT/EP2000/005231 external-priority patent/WO2000076544A1/en
Publication of BR0012121A publication Critical patent/BR0012121A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"DERIVADO DE AMINOTETRALINA PARA TERAPIA DE DOENçAS CARDIOVASCULARES". A disfunção ventricular esquerda é tratada através de um processo que abrange: A administração de uma quantidade terapeuticamente eficaz de 5,6-diidroxi-2-metilaminotetralina, ou 5,6-diisobutiroil-oxi-2-metil-aminotetralina, ou um sal farmaceuticamente aceitável em combinação com um inibidor de enzima conversora de angiotensina ao indivíduo que sofre de remodelagem ventricular esquerda.
BR0012121-5A 1999-06-09 2000-06-07 Derivado de aminotetralina para terapia de doenças cardiovasculares BR0012121A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/328,434 US6103760A (en) 1995-03-17 1999-06-09 Aminotetralin derivative for the therapy of cardiovascular diseases
PCT/EP2000/005231 WO2000076544A1 (en) 1996-03-13 2000-06-07 Aminotetralin derivative for the therapy of cardiovascular diseases

Publications (1)

Publication Number Publication Date
BR0012121A true BR0012121A (pt) 2002-05-14

Family

ID=23280968

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012121-5A BR0012121A (pt) 1999-06-09 2000-06-07 Derivado de aminotetralina para terapia de doenças cardiovasculares

Country Status (27)

Country Link
US (2) US6576671B1 (pt)
EP (1) EP1183046B1 (pt)
JP (1) JP2003501483A (pt)
KR (1) KR20020005772A (pt)
CN (1) CN1354676A (pt)
AT (1) ATE248607T1 (pt)
AU (1) AU766230B2 (pt)
BR (1) BR0012121A (pt)
CA (1) CA2376715A1 (pt)
CZ (1) CZ20014406A3 (pt)
DE (1) DE60004996T2 (pt)
DK (1) DK1183046T3 (pt)
EA (1) EA003830B1 (pt)
EE (1) EE200100663A (pt)
ES (1) ES2206240T3 (pt)
HK (1) HK1044279B (pt)
HU (1) HUP0201650A2 (pt)
IL (1) IL146962A0 (pt)
MA (1) MA26796A1 (pt)
MX (1) MXPA01012638A (pt)
NO (1) NO20016000L (pt)
NZ (1) NZ515727A (pt)
PL (1) PL352119A1 (pt)
PT (1) PT1183046E (pt)
SK (1) SK18012001A3 (pt)
TR (1) TR200103526T2 (pt)
ZA (1) ZA200110091B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10053397A1 (de) * 2000-10-20 2002-05-02 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
DE10043321B4 (de) * 2000-08-24 2005-07-28 Neurobiotec Gmbh Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung
DE10064453A1 (de) * 2000-12-16 2002-07-04 Schering Ag Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
US20050101668A1 (en) * 2003-07-24 2005-05-12 Chiesi Farmaceutici S.P.A. Aminotetralin derivatives as a medicament for the treatment and prevention of myocardial ischemic conditions
EP1500392A1 (en) * 2003-07-24 2005-01-26 CHIESI FARMACEUTICI S.p.A. Aminotetralin derivatives as a medicament for the treatment and prevention of myocardial ischemic conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134997A (en) * 1977-03-01 1979-01-16 University Of Iowa Research Foundation Effect of an aminotetralin derivative on coronary blood flow in infarcted hearts
IT1275935B1 (it) * 1995-03-17 1997-10-24 Chiesi Farma Spa Derivato di aminotetralina per la terapia di malattie cardiovascolari

Also Published As

Publication number Publication date
EA200101159A1 (ru) 2002-06-27
HUP0201650A2 (hu) 2002-12-28
DE60004996D1 (de) 2003-10-09
EA003830B1 (ru) 2003-10-30
PT1183046E (pt) 2003-12-31
JP2003501483A (ja) 2003-01-14
DK1183046T3 (da) 2004-01-05
US6576671B1 (en) 2003-06-10
HK1044279A1 (en) 2002-10-18
AU5076500A (en) 2001-01-02
MXPA01012638A (es) 2002-07-22
ZA200110091B (en) 2002-12-09
EP1183046A1 (en) 2002-03-06
NZ515727A (en) 2003-06-30
EP1183046B1 (en) 2003-09-03
MA26796A1 (fr) 2004-12-20
NO20016000D0 (no) 2001-12-07
DE60004996T2 (de) 2004-07-22
NO20016000L (no) 2002-02-11
ATE248607T1 (de) 2003-09-15
ES2206240T3 (es) 2004-05-16
CZ20014406A3 (cs) 2002-04-17
CA2376715A1 (en) 2000-12-21
EE200100663A (et) 2003-04-15
KR20020005772A (ko) 2002-01-17
AU766230B2 (en) 2003-10-09
SK18012001A3 (sk) 2002-04-04
US20030207944A1 (en) 2003-11-06
TR200103526T2 (tr) 2002-04-22
CN1354676A (zh) 2002-06-19
HK1044279B (en) 2004-01-16
IL146962A0 (en) 2002-08-14
PL352119A1 (en) 2003-07-28

Similar Documents

Publication Publication Date Title
BR0005266A (pt) Compostos para o tratamento de disfução sexual feminina
KR970704429A (ko) 심혈관 질환의 치료를 위한 드롤록시펜의 용도(use of droloxifene for the treatment of cardiovascular diseases)
BR9909277A (pt) Compostos com atividade em receptores muscarìnicos
AU7321598A (en) Use of cholinesterase inhibitors to treat disorders of attention
PT725635E (pt) Fenilacetato e derivados isoladamente ou em combinacao com outros compostos contra estados neoplasticos e outras perturbacoes
GT199900015A (es) Procedimiento para tratar la insuficiencia cardiaca
CA2383785A1 (en) Methods of using rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction
BR0212252A (pt) Métodos para reduzir a hipertensão e a insuficiência cardìaca em um mamìfero
DE69935720D1 (de) Diamino-propanol-verbindungen zur behandlung von ischaemien
EP0699439A3 (en) Treatment of diseases caused by sebum with inhibitors of acyl CoA cholesterol acyltransferase
BR0012121A (pt) Derivado de aminotetralina para terapia de doenças cardiovasculares
NO990450L (no) Behandling av sinnslidelser
PT862454E (pt) Novas utilizacoes de ctla-8 de mamifero e reagentes relacionados
BR9809376A (pt) Pregnan-3-ol-20-onas
AR022475A1 (es) Metodo para la prevencion o reduccion de eventos cardiovasculares asociados con intervencion coronaria.
EP1331004A3 (en) Aminotetralin Derivative for the Therapy of Cardiovascular Diseases
MX9605153A (es) Agentes farmaceuticos para el tratamiento de enfermedades inflamatorias cronicas y agudas.
MX9704887A (es) Composiciones farmaceuticas para el tratamiento de trastornos depresivos.
BR0007921A (pt) Processo para prevenção ou redução de eventos cardiovasculares associados com intervenção coronária
AR033424A1 (es) Composiciones farmaceuticas

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.