BR0014803A - Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico - Google Patents

Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico

Info

Publication number
BR0014803A
BR0014803A BR0014803-2A BR0014803A BR0014803A BR 0014803 A BR0014803 A BR 0014803A BR 0014803 A BR0014803 A BR 0014803A BR 0014803 A BR0014803 A BR 0014803A
Authority
BR
Brazil
Prior art keywords
amino acids
peptides
ser
peptide
composition
Prior art date
Application number
BR0014803-2A
Other languages
English (en)
Inventor
Catherina Joanna Staveren
Cornelis Marius Timmers
Philippus Johannes Marie Galen
Ronald Marcellus Alpho Knegtel
Anna Maria Helena Boots
Andreas Martinus Ma Miltenburg
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of BR0014803A publication Critical patent/BR0014803A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Mycology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"PEPTìDEO, COMPOSIçãO FARMACêUTICA, USO DE UM OU MAIS DOS PEPTìDEOS, E, COMPOSIçãO DE DIAGNóSTICO". A invenção diz respeito a um peptìdeo modificado derivado de H-Arg-Ser-Phe-Thr-Leu-Ala-Ser-Ser-Glu-Thr-Gly-Val-Gly-OH tendo a fórmula geral (II): Q-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-Z. Na fórmula geral (II), A1 até A13 correspondem com os aminoácidos da Fórmula (I), Q corresponde com H e Z corresponde com OH. As modificações de acordo com a presente invenção são selecionadas de um ou mais dos grupos a, b ou c, consistindo de a) substituição de 1 a 6, preferivelmente de 1 a 4 aminoácidos em A1 até A13 com aminoácidos não naturais ou <225> aminoácidos; b) substituição de uma ou mais ligações de amida com ligações de amida reduzidas ou isósteros de etileno; c) substituições em Q e/ou Z e, opcionalmente, d) substituição de aminoácidos naturais até um total de 6 modificações. Os peptídeos podem ser usados para induzir a indução de tolerância em pacientes que sofrem de doenças autoimunes.
BR0014803-2A 1999-10-18 2000-10-12 Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico BR0014803A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203427 1999-10-18
PCT/EP2000/010230 WO2001029081A1 (en) 1999-10-18 2000-10-12 Modified peptides and peptidomimetics for use in immunotherapy

Publications (1)

Publication Number Publication Date
BR0014803A true BR0014803A (pt) 2002-06-11

Family

ID=8240756

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0014803-2A BR0014803A (pt) 1999-10-18 2000-10-12 Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição de diagnóstico

Country Status (23)

Country Link
EP (1) EP1226167A1 (pt)
JP (1) JP2003512388A (pt)
KR (1) KR20020047245A (pt)
CN (1) CN1379786A (pt)
AR (1) AR026068A1 (pt)
AU (1) AU780238B2 (pt)
BR (1) BR0014803A (pt)
CA (1) CA2386398A1 (pt)
CO (1) CO5271650A1 (pt)
CZ (1) CZ20021356A3 (pt)
HK (1) HK1046693A1 (pt)
HU (1) HUP0203504A3 (pt)
IL (1) IL148778A0 (pt)
MX (1) MXPA02003520A (pt)
NO (1) NO20021763L (pt)
NZ (1) NZ518256A (pt)
PE (1) PE20010692A1 (pt)
PL (1) PL354590A1 (pt)
RU (1) RU2002113107A (pt)
SK (1) SK6842002A3 (pt)
TR (1) TR200201036T2 (pt)
WO (1) WO2001029081A1 (pt)
ZA (1) ZA200202577B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002951212A0 (en) * 2002-09-04 2002-09-19 Monash University A method of modulating cellular activity and molecules for use therein
EP2016054A2 (en) * 2006-04-06 2009-01-21 Purdue Research Foundation Derivatization-enhanced analysis of amino acids and peptides
US20100278745A1 (en) * 2006-12-21 2010-11-04 Norbert Lange Compounds for fluorescence imaging
AU2009207922B2 (en) 2008-01-23 2015-05-14 Herlev Hospital YKL-40 as a general marker for non-specific disease
NZ592241A (en) 2008-09-15 2012-11-30 Herlev Hospital Ykl-40 as a marker for gastrointestinal cancers
WO2016073949A1 (en) 2014-11-07 2016-05-12 Kineta Three, Llp Modifications and uses of conotoxin peptides
EP3466963A1 (en) * 2017-10-05 2019-04-10 Suigeneris Farmacosmetics, S.L. Anticancer peptides and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115744A (en) * 1994-10-27 2000-07-16 Akzo Nobel Nv Peptides comprising a subsequence of human cartilage glycoprotein - 39
IL120561A0 (en) * 1996-04-24 1997-07-13 Akzo Nobel Nv Peptides suitable for use in immunosuppressive therapy
WO1997046578A1 (en) * 1996-06-07 1997-12-11 Zeneca Limited Peptide derivatives
IL122233A (en) * 1996-12-06 2001-04-30 Akzo Nobel Nv Method of generating monoclonal antibodies to cell wall and pharmaceutical preparations and diagnostic agents containing them

Also Published As

Publication number Publication date
EP1226167A1 (en) 2002-07-31
CZ20021356A3 (cs) 2002-07-17
RU2002113107A (ru) 2004-01-10
MXPA02003520A (es) 2002-08-20
JP2003512388A (ja) 2003-04-02
NZ518256A (en) 2004-01-30
SK6842002A3 (en) 2002-09-10
NO20021763D0 (no) 2002-04-15
HK1046693A1 (zh) 2003-01-24
NO20021763L (no) 2002-04-15
AU1139601A (en) 2001-04-30
WO2001029081A1 (en) 2001-04-26
CA2386398A1 (en) 2001-04-26
PL354590A1 (en) 2004-01-26
IL148778A0 (en) 2002-09-12
PE20010692A1 (es) 2001-07-06
CN1379786A (zh) 2002-11-13
TR200201036T2 (tr) 2002-08-21
KR20020047245A (ko) 2002-06-21
CO5271650A1 (es) 2003-04-30
HUP0203504A3 (en) 2005-03-29
HUP0203504A2 (hu) 2003-04-28
AU780238B2 (en) 2005-03-10
ZA200202577B (en) 2003-09-23
AR026068A1 (es) 2002-12-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A E 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.