BR0016168A - Combinações terapêuticas de (s)-2-(benzilaminometil)-2,3,8,9tetrahidro-7h-1,4-dioxi no[2,3 -e]indol-8-ona e neurolépticos para o tratamento ou prevenção de distúrbios psicóticos - Google Patents

Combinações terapêuticas de (s)-2-(benzilaminometil)-2,3,8,9tetrahidro-7h-1,4-dioxi no[2,3 -e]indol-8-ona e neurolépticos para o tratamento ou prevenção de distúrbios psicóticos

Info

Publication number: BR0016168A
Authority: BR; Brazil
Prior art keywords: prevention; treatment; neuroleptics; therapeutic combinations; benzylaminomethyl
Prior art date: 1999-12-10

Application number

BR0016168-3A

Other languages

English (en)

Portuguese (pt)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-10

Filing date

2000-12-07

Publication date

2002-08-20

2000-12-07 Application filed filed Critical

2002-08-20 Publication of BR0016168A publication Critical patent/BR0016168A/pt

Links

230000002265 prevention Effects 0.000 title abstract 4
238000011282 treatment Methods 0.000 title abstract 4
208000028017 Psychotic disease Diseases 0.000 title abstract 3
230000001225 therapeutic effect Effects 0.000 title abstract 3
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
-1 benzylaminomethyl Chemical group 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

BR0016168-3A 1999-12-10 2000-12-07 Combinações terapêuticas de (s)-2-(benzilaminometil)-2,3,8,9tetrahidro-7h-1,4-dioxi no[2,3 -e]indol-8-ona e neurolépticos para o tratamento ou prevenção de distúrbios psicóticos BR0016168A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45860799A	1999-12-10	1999-12-10
PCT/US2000/033060 WO2001041750A2 (en)	1999-12-10	2000-12-07	Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (1)

Publication Number	Publication Date
BR0016168A true BR0016168A (pt)	2002-08-20

Family

ID=23821437

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR0016168-3A BR0016168A (pt)	1999-12-10	2000-12-07	Combinações terapêuticas de (s)-2-(benzilaminometil)-2,3,8,9tetrahidro-7h-1,4-dioxi no[2,3 -e]indol-8-ona e neurolépticos para o tratamento ou prevenção de distúrbios psicóticos

Country Status (20)

Country	Link
EP (1)	EP1235570A2 (cs)
JP (1)	JP5557409B2 (cs)
KR (1)	KR100772854B1 (cs)
CN (1)	CN1230164C (cs)
AR (1)	AR026756A1 (cs)
AU (1)	AU784211B2 (cs)
BR (1)	BR0016168A (cs)
CA (1)	CA2396351C (cs)
CZ (1)	CZ20021880A3 (cs)
EA (1)	EA005002B1 (cs)
HK (1)	HK1045942A1 (cs)
HU (1)	HUP0203309A3 (cs)
IL (2)	IL149669A0 (cs)
MX (1)	MXPA02005649A (cs)
NO (1)	NO20022739D0 (cs)
NZ (1)	NZ519381A (cs)
PL (1)	PL355292A1 (cs)
TW (1)	TWI222864B (cs)
WO (1)	WO2001041750A2 (cs)
ZA (1)	ZA200205484B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5547865B2 (ja)	2003-10-29	2014-07-16	ワイス・エルエルシー	アプリンドルおよびその誘導体を含む持続放出型医薬組成物
JP2008530229A (ja)	2005-02-17	2008-08-07	ワイス	シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
EP2254598B1 (en) *	2008-02-13	2013-07-10	Targacept, Inc.	Combination of alpha 7 nicotinic agonists and antipsychotics
EP3906927B1 (en) *	2020-05-04	2022-05-25	BIOPROJET Pharma	Use of dopamine d3 partial agonists for treating central nervous system disorders
GB202014184D0 (en)	2020-09-09	2020-10-21	Johnson Matthey Plc	Modifed catalyst supports and catalysts supported thereon

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2987484B2 (ja) *	1995-03-16	1999-12-06	大塚製薬株式会社	カルボスチリル誘導体の製造方法
US5756532A (en) *	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) *	1996-12-27	1997-02-12	Knoll Ag	Therapeutic agents

2000
- 2000-12-07 BR BR0016168-3A patent/BR0016168A/pt not_active Application Discontinuation
- 2000-12-07 KR KR1020027007286A patent/KR100772854B1/ko not_active Expired - Fee Related
- 2000-12-07 CZ CZ20021880A patent/CZ20021880A3/cs unknown
- 2000-12-07 MX MXPA02005649A patent/MXPA02005649A/es active IP Right Grant
- 2000-12-07 IL IL14966900A patent/IL149669A0/xx active IP Right Grant
- 2000-12-07 EP EP00982461A patent/EP1235570A2/en not_active Withdrawn
- 2000-12-07 PL PL00355292A patent/PL355292A1/xx not_active Application Discontinuation
- 2000-12-07 JP JP2001543095A patent/JP5557409B2/ja not_active Expired - Lifetime
- 2000-12-07 EA EA200200656A patent/EA005002B1/ru not_active IP Right Cessation
- 2000-12-07 NZ NZ519381A patent/NZ519381A/en unknown
- 2000-12-07 HK HK02107378.5A patent/HK1045942A1/zh unknown
- 2000-12-07 AU AU19490/01A patent/AU784211B2/en not_active Ceased
- 2000-12-07 CA CA002396351A patent/CA2396351C/en not_active Expired - Lifetime
- 2000-12-07 HU HU0203309A patent/HUP0203309A3/hu unknown
- 2000-12-07 AR ARP000106504A patent/AR026756A1/es unknown
- 2000-12-07 CN CNB008169527A patent/CN1230164C/zh not_active Expired - Lifetime
- 2000-12-07 WO PCT/US2000/033060 patent/WO2001041750A2/en not_active Ceased
- 2000-12-08 TW TW089126071A patent/TWI222864B/zh not_active IP Right Cessation
2002
- 2002-05-15 IL IL149669A patent/IL149669A/en not_active IP Right Cessation
- 2002-06-07 NO NO20022739A patent/NO20022739D0/no not_active Application Discontinuation
- 2002-07-09 ZA ZA200205484A patent/ZA200205484B/xx unknown

Also Published As

Publication number	Publication date
IL149669A0 (en)	2002-11-10
KR20030016207A (ko)	2003-02-26
AU1949001A (en)	2001-06-18
KR100772854B1 (ko)	2007-11-02
IL149669A (en)	2006-06-11
NO20022739L (no)	2002-06-07
MXPA02005649A (es)	2004-09-10
AR026756A1 (es)	2003-02-26
CA2396351A1 (en)	2001-06-14
HK1045942A1 (zh)	2002-12-20
NO20022739D0 (no)	2002-06-07
ZA200205484B (en)	2003-12-31
WO2001041750A2 (en)	2001-06-14
TWI222864B (en)	2004-11-01
HUP0203309A2 (hu)	2003-01-28
JP5557409B2 (ja)	2014-07-23
CN1409633A (zh)	2003-04-09
EA200200656A1 (ru)	2002-12-26
JP2003516350A (ja)	2003-05-13
HUP0203309A3 (en)	2004-12-28
PL355292A1 (en)	2004-04-05
EA005002B1 (ru)	2004-10-28
NZ519381A (en)	2004-04-30
CN1230164C (zh)	2005-12-07
EP1235570A2 (en)	2002-09-04
WO2001041750A3 (en)	2002-02-14
CZ20021880A3 (cs)	2002-08-14
AU784211B2 (en)	2006-02-23
CA2396351C (en)	2009-11-10

Legal Events

Date	Code	Title	Description
2009-09-15	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2010-07-06	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10, 13 E 25 DA LPI.
2011-02-01	B12B	Appeal against refusal [chapter 12.2 patent gazette]

Publication	Publication Date	Title
IL152659A (en)	2010-12-30	Liquid pharmaceutical compositions comprising a pegylated human erythropoietin protein and a multiple charged inorganic anion, in a pharmaceutically acceptable buffer
BR0015416A (pt)	2002-07-16	Composições contendo derivados do ácido hidroxieicosa tetraenóico e métodos de uso no tratamento de distúrbios de olhos secos
CO4910133A1 (es)	2000-04-24	Antagonistas de 5-h[1f]
ATE231872T1 (de)	2003-02-15	Thiazolopyrimidinderivate
TNSN04034A1 (en)	2006-06-01	Combined preparations, containing 1,4-benzothiepine-1,1-dioxide derivatives and other active substances, and the use thereof
PL1654253T3 (pl)	2007-05-31	Podstawione pochodne 3-pirolidynoindolu
BR0316296A (pt)	2005-12-13	Compostos lapacone e seus métodos de uso
CA2284551A1 (en)	1998-10-08	New therapeutic combinations of mirtazapine and antipsychotic agents, for the treatment or prophylaxis of psychotic disorders
AU2001266152A1 (en)	2002-01-02	Novel substituted nitrocatechols, their use in the treatment of some central andperipheral nervous system disorders and pharmaceutical compositions containing them
YU13301A (sh)	2005-06-10	Muskarinski agonisti i antagonisti
SE9802208D0 (sv)	1998-06-22	Novel compounds
AU2001290480A1 (en)	2002-04-08	Cyclized benzamide neurokinin antagonists for use in therapy
SE9802209D0 (sv)	1998-06-22	Novel compounds
ES2175356T3 (es)	2002-11-16	Uso de (+)-alfa-(2,3-dimetoxifenil)-1-[2-(4 fluorofenil)et il[-4- piperidinmetanol en el tratamiento de trastornos depresivos y trastornos bipolares.
TW374085B (en)	1999-11-11	Novel piperidine derivatives, their preparation, pharmaceutical formulation and medical use
JO2199B1 (en)	2003-12-23	Replaced pyrrols
PL368040A1 (en)	2005-03-21	Substituted 4-aminocyclohexanol derivatives
NO20022739D0 (no)	2002-06-07	Nye terapeutiske kombinasjoner av (S)-2-(benzylamino-metyl)- 2,3,8,9-tetrahydro-7H-1,4-dioksino[2,3-e]indol-8-on ognevroleptika for behandling eller forhindring av psykotiskelidelser
IT1320192B1 (it)	2003-11-26	Composizione terapeutica per la cura della psoriasi.
HUP0204258A3 (en)	2005-03-29	Use of vitamin d-derivatives for preparation of pharmaceutical compositions useful in the treatment of osteoporosis and related bone disorders, as well as novel vitamin d3-derivatives
MXPA02003731A (es)	2003-12-11	Derivados novedosos de acido fusidico.
BR9812002A (pt)	2000-09-26	Compostos com efeito antiprimeiro-passe
WO1999019324A3 (en)	1999-07-01	Antipsychotic substituted piperidine derivatives
WO2003040119A8 (fr)	2003-11-27	Inhibiteurs de l'angiogenese
AUPQ902000A0 (en)	2000-08-17	Pharmaceutical composition for the treatment of skin conditions