BR0016652A - Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo - Google Patents
Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduoInfo
- Publication number
- BR0016652A BR0016652A BR0016652-9A BR0016652A BR0016652A BR 0016652 A BR0016652 A BR 0016652A BR 0016652 A BR0016652 A BR 0016652A BR 0016652 A BR0016652 A BR 0016652A
- Authority
- BR
- Brazil
- Prior art keywords
- amyloid angiopathy
- cerebral amyloid
- individual
- methods
- treat
- Prior art date
Links
- 208000005145 Cerebral amyloid angiopathy Diseases 0.000 title abstract 8
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17187799P | 1999-12-23 | 1999-12-23 | |
| PCT/IB2000/002078 WO2001085093A2 (en) | 1999-12-23 | 2000-12-22 | Compounds and methods for modulating cerebral amyloid angiopathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0016652A true BR0016652A (pt) | 2002-11-19 |
Family
ID=22625484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0016652-9A BR0016652A (pt) | 1999-12-23 | 2000-12-22 | Métodos para inibir angiopatia amilóide cerebral, para tratar um estado de doença caracterizado por angiopatia amilóide cerebral em um indivìduo, e para diagnosticar angiopatia amilóide cerebral em um indivìduo |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6670399B2 (pt) |
| EP (1) | EP1251837A2 (pt) |
| JP (1) | JP2003532656A (pt) |
| KR (3) | KR20090016517A (pt) |
| CN (1) | CN1434706A (pt) |
| AU (1) | AU8431301A (pt) |
| BR (1) | BR0016652A (pt) |
| CA (1) | CA2395314A1 (pt) |
| IL (1) | IL150374A0 (pt) |
| MX (1) | MXPA02006196A (pt) |
| WO (1) | WO2001085093A2 (pt) |
Families Citing this family (70)
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| US20040208875A1 (en) * | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
| US20020022657A1 (en) * | 1998-02-11 | 2002-02-21 | Francine Gervais | Methods for modulating neuronal cell death |
| US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
| US7060670B1 (en) * | 1999-05-05 | 2006-06-13 | Neurochem (International) Limited | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
| EP1237547A2 (en) * | 1999-07-09 | 2002-09-11 | Isis Innovation Limited | Compounds for inhibiting diseases and preparing cells for transplantation |
| US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
| US20070135337A2 (en) * | 1999-11-29 | 2007-06-14 | Neurochem (International) Limited | Vaccine for the Prevention and Treatment of Alzheimer's and Amyloid Related Diseases |
| EP1251837A2 (en) * | 1999-12-23 | 2002-10-30 | Neurochem, Inc. | Compounds and methods for modulating cerebral amyloid angiopathy |
| US7311893B2 (en) * | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
| WO2003074008A2 (en) * | 2002-03-01 | 2003-09-12 | Merck & Co., Inc. | Aminoalkylphosphonates and related compounds as edg receptor agonists |
| CN1753662A (zh) * | 2002-12-24 | 2006-03-29 | 神经化学(国际)有限公司 | 用于治疗β-淀粉状蛋白相关疾病的治疗制剂 |
| AU2003292936A1 (en) * | 2002-12-24 | 2004-07-22 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| EP1477493A1 (en) * | 2003-05-15 | 2004-11-17 | Bayer HealthCare AG | Isotope coded affinity tags |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| BRPI0411800A (pt) * | 2003-06-23 | 2006-08-08 | Neurochem Int Ltd | candidatos a fármacos e métodos para sua preparação |
| AU2011250847B2 (en) * | 2003-06-23 | 2013-06-20 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
| US20050142191A1 (en) * | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| US20060079578A1 (en) * | 2003-06-23 | 2006-04-13 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
| EP1644325A2 (en) * | 2003-06-23 | 2006-04-12 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7414076B2 (en) * | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7262223B2 (en) | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
| EP1841460A2 (en) * | 2004-06-18 | 2007-10-10 | Neurochem (International) Limited | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| CN101035523A (zh) | 2004-07-09 | 2007-09-12 | 西格马-奥利奇有限公司 | 旋光增加的手性离子液体 |
| US8168830B2 (en) | 2004-07-23 | 2012-05-01 | Sigma-Aldrich Co. Llc | High stability diionic liquid salts |
| JP5806440B2 (ja) | 2004-07-23 | 2015-11-10 | シグマ−アルドリッチ・カンパニー、エルエルシー | 高安定性の二イオン液体塩 |
| US20090215717A1 (en) * | 2004-08-05 | 2009-08-27 | Ivax Drug Research Institute Ltd. | Sulfated oligosaccharides |
| CN101103018A (zh) * | 2004-11-16 | 2008-01-09 | 神经化学(国际)有限公司 | 治疗cns和淀粉样蛋白-相关疾病的化合物 |
| US20080025962A1 (en) * | 2004-11-30 | 2008-01-31 | Angesmg,Inc. | Remedy for Alzheimer's Disease |
| BRPI0519243A2 (pt) * | 2004-12-22 | 2009-01-06 | Neurochem Int Ltd | mÉtodos e composiÇÕes para tratar doenÇas relacionadas a amilàide |
| CA2611586A1 (en) * | 2005-04-12 | 2007-06-21 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| TW200716088A (en) * | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| WO2007023389A2 (en) * | 2005-07-21 | 2007-03-01 | Neurochem (International) Limited | Polymorphic forms of 3-amino-1-propanesulfonic acid |
| HRP20140240T4 (hr) | 2005-11-30 | 2017-02-24 | Abbvie Inc. | Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba |
| US8691224B2 (en) | 2005-11-30 | 2014-04-08 | Abbvie Inc. | Anti-Aβ globulomer 5F7 antibodies |
| MX2008008213A (es) * | 2005-12-22 | 2008-09-03 | Neurochem Int Ltd | Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias. |
| DK2089417T3 (en) | 2006-10-12 | 2015-03-23 | Bhi Ltd Partnership | Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid |
| US8188046B2 (en) * | 2006-10-16 | 2012-05-29 | University Of South Florida | Amyloid beta peptides and methods of use |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| JP2010513219A (ja) * | 2006-12-22 | 2010-04-30 | ベラス ヘルス (インターナショナル) リミテッド | 腎臓の疾患、糖尿病性腎症及び脂質代謝異常の治療 |
| US8097721B2 (en) | 2007-01-31 | 2012-01-17 | Sigma-Aldrich Co. Llc | High stability polyionic liquid salts |
| US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| US7618944B2 (en) * | 2007-03-01 | 2009-11-17 | Intezyne Technologies, Inc. | Encapsulated amyloid-beta peptides |
| GB0708507D0 (en) * | 2007-05-02 | 2007-06-13 | Queen Mary & Westfield College | Substituted phosphonates and their use |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| JP2010535193A (ja) * | 2007-08-01 | 2010-11-18 | サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク セエンエールエス | チオホスフィン(チオホスホン)酸誘導体およびそれらの治療適用 |
| US20090076167A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched tramiprosate |
| AU2008311367B2 (en) | 2007-10-05 | 2014-11-13 | Ac Immune S.A. | Use of anti-amyloid beta antibody in ocular diseases |
| US8231895B2 (en) | 2008-05-22 | 2012-07-31 | Universidade De Coimbra | Targeted delivery to human diseases and disorders |
| EP2180003A1 (en) * | 2008-10-21 | 2010-04-28 | Zentiva, k.s. | Preparation of ibandronate trisodium |
| US9023767B2 (en) * | 2009-05-07 | 2015-05-05 | Memorial Sloan-Kettering Cancer Center | γ-Secretase substrates and methods of use |
| MX2012001671A (es) * | 2009-08-10 | 2012-04-30 | Bellus Health Inc | Metodos, compuestos y composiciones para la administracion de acido 1,3-propanedisulfonico. |
| EP2289900A1 (en) * | 2009-08-26 | 2011-03-02 | Humboldt Universität zu Berlin | Bisphosphonates as inhibitors of acid sphingomyelinase |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| EP2598882B1 (en) | 2010-07-30 | 2017-07-26 | AC Immune S.A. | Safe and functional humanized antibodies for use in treating an amyloidosis |
| EP3533803B1 (en) | 2010-08-14 | 2021-10-27 | AbbVie Inc. | Anti-amyloid-beta antibodies |
| CN103502466A (zh) | 2010-09-07 | 2014-01-08 | 斯隆-凯特林纪念癌症中心 | 用于γ-分泌酶测定的方法和组合物 |
| US12085575B2 (en) | 2011-12-01 | 2024-09-10 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for detecting proteinopathies |
| US9599626B2 (en) * | 2011-12-01 | 2017-03-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Therapeutic and diagnostic method for ataxia-telangiectasia |
| US10962553B2 (en) | 2011-12-01 | 2021-03-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for detecting proteinopathies |
| WO2013158846A1 (en) * | 2012-04-20 | 2013-10-24 | Baylor College Of Medicine | Novel dxr inhibitors for antimicrobial therapy |
| CN102793694B (zh) * | 2012-08-14 | 2014-06-04 | 武汉华纳联合药业有限公司 | 3-氨基-1-丙烷磺酸及其衍生物在制备治疗脑卒中的药物中的应用 |
| JP5804463B2 (ja) | 2012-12-27 | 2015-11-04 | 国立研究開発法人科学技術振興機構 | 環状ペプチド及びこれを含有する医薬 |
| CN114805211B (zh) | 2017-03-21 | 2024-08-23 | 润佳(苏州)医药科技有限公司 | 同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途 |
| ES3003810T3 (en) * | 2017-04-17 | 2025-03-11 | Univ Kyoto | Optically-active 2-amino-phosphonoalkane acid, optically-active 2-amino-phosphonoalkane acid salt, and hydrates of these |
| RU2696684C1 (ru) * | 2018-09-18 | 2019-08-05 | Федеральное государственное бюджетное научное учреждение "Научный центр неврологии" (ФГБНУ НЦН) | Способ определения типов когнитивных расстройств у больных церебральной микроангиопатией |
| CN116059192B (zh) | 2019-11-13 | 2024-10-29 | 润佳(苏州)医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸及其衍生物的用途 |
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-
2000
- 2000-12-22 EP EP00993855A patent/EP1251837A2/en not_active Withdrawn
- 2000-12-22 KR KR1020097001295A patent/KR20090016517A/ko not_active Ceased
- 2000-12-22 IL IL15037400A patent/IL150374A0/xx unknown
- 2000-12-22 JP JP2001581748A patent/JP2003532656A/ja active Pending
- 2000-12-22 CA CA002395314A patent/CA2395314A1/en not_active Abandoned
- 2000-12-22 CN CN00819104A patent/CN1434706A/zh active Pending
- 2000-12-22 AU AU84313/01A patent/AU8431301A/en not_active Abandoned
- 2000-12-22 MX MXPA02006196A patent/MXPA02006196A/es not_active Application Discontinuation
- 2000-12-22 KR KR1020027008226A patent/KR20020063266A/ko not_active Ceased
- 2000-12-22 US US09/747,408 patent/US6670399B2/en not_active Expired - Fee Related
- 2000-12-22 KR KR1020077030145A patent/KR20080003945A/ko not_active Ceased
- 2000-12-22 WO PCT/IB2000/002078 patent/WO2001085093A2/en not_active Ceased
- 2000-12-22 BR BR0016652-9A patent/BR0016652A/pt not_active Application Discontinuation
-
2003
- 2003-11-10 US US10/705,028 patent/US20080317834A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030003141A1 (en) | 2003-01-02 |
| EP1251837A2 (en) | 2002-10-30 |
| JP2003532656A (ja) | 2003-11-05 |
| AU8431301A (en) | 2001-11-20 |
| WO2001085093A3 (en) | 2002-08-29 |
| WO2001085093A2 (en) | 2001-11-15 |
| IL150374A0 (en) | 2002-12-01 |
| CA2395314A1 (en) | 2001-11-15 |
| KR20020063266A (ko) | 2002-08-01 |
| CN1434706A (zh) | 2003-08-06 |
| US20080317834A1 (en) | 2008-12-25 |
| KR20090016517A (ko) | 2009-02-13 |
| US6670399B2 (en) | 2003-12-30 |
| KR20080003945A (ko) | 2008-01-08 |
| MXPA02006196A (es) | 2002-12-09 |
| WO2001085093A9 (en) | 2002-09-26 |
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