BR0016672A - Constructo de vacina de ácido nucleico, composição de vacina, uso de um constructo de vacina de ácido nucleico, e, método de vacinação de um mamìfero contra tumores - Google Patents
Constructo de vacina de ácido nucleico, composição de vacina, uso de um constructo de vacina de ácido nucleico, e, método de vacinação de um mamìfero contra tumoresInfo
- Publication number
- BR0016672A BR0016672A BR0016672-3A BR0016672A BR0016672A BR 0016672 A BR0016672 A BR 0016672A BR 0016672 A BR0016672 A BR 0016672A BR 0016672 A BR0016672 A BR 0016672A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- acid vaccine
- vaccine construct
- construct
- vaccination
- Prior art date
Links
- 108700001237 Nucleic Acid-Based Vaccines Proteins 0.000 title abstract 5
- 229940023146 nucleic acid vaccine Drugs 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002255 vaccination Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 1
- 230000013595 glycosylation Effects 0.000 abstract 3
- 238000006206 glycosylation reaction Methods 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/00117—Mucins, e.g. MUC-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"CONSTRUCTO DE VACINA DE áCIDO NUCLEICO, COMPOSIçãO DE VACINA, USO DE UM CONSTRUCTO DE VACINA DE áCIDO NUCLEICO, E, MéTODO DE VACINAçãO DE UM MAMìFERO CONTRA TUMORES". Um constructo de vacina de ácido nucleico compreendendo um polinucleotídeo isolado que codifica um polipeptídeo compreendendo pelo menos cinco resíduos de aminoácido consecutivos do monómero VNTR de Mucl no qual um ou mais dos citados aminoácidos é um sítio de glicosilação, caracterizado pelo fato de que quando o polinucleotídeo isolado é expressado em uma célula de mamífero, a glicosilação do polipeptídeo resultante é alterada ou prevenida em pelo menos um dos citados sítios de glicosilação.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930359.6A GB9930359D0 (en) | 1999-12-22 | 1999-12-22 | Novel polypeptides |
| PCT/GB2000/004906 WO2001046228A2 (en) | 1999-12-22 | 2000-12-20 | Nucleic acid vaccination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0016672A true BR0016672A (pt) | 2002-10-08 |
Family
ID=10866857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0016672-3A BR0016672A (pt) | 1999-12-22 | 2000-12-20 | Constructo de vacina de ácido nucleico, composição de vacina, uso de um constructo de vacina de ácido nucleico, e, método de vacinação de um mamìfero contra tumores |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20030133909A1 (pt) |
| EP (1) | EP1240317B1 (pt) |
| JP (1) | JP2003517845A (pt) |
| KR (1) | KR20020073149A (pt) |
| CN (1) | CN1434862A (pt) |
| AT (1) | ATE355365T1 (pt) |
| AU (1) | AU2204901A (pt) |
| BR (1) | BR0016672A (pt) |
| CA (1) | CA2395208A1 (pt) |
| CZ (1) | CZ20022192A3 (pt) |
| DE (1) | DE60033690T2 (pt) |
| ES (1) | ES2282156T3 (pt) |
| GB (1) | GB9930359D0 (pt) |
| HU (1) | HUP0203848A3 (pt) |
| IL (1) | IL150285A0 (pt) |
| MX (1) | MXPA02006313A (pt) |
| NO (1) | NO20023010L (pt) |
| NZ (1) | NZ519732A (pt) |
| PL (1) | PL356697A1 (pt) |
| WO (1) | WO2001046228A2 (pt) |
| ZA (1) | ZA200204987B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0212046D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| GB0304634D0 (en) * | 2003-02-28 | 2003-04-02 | Glaxo Group Ltd | Vaccines |
| GB0321615D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
| MX2018008797A (es) | 2016-01-19 | 2018-11-29 | Pfizer | Vacunas contra el cancer. |
| CN106086050B (zh) * | 2016-06-28 | 2020-01-07 | 中国人民解放军第二军医大学 | 携带muc1肿瘤抗原表位pdtrp的嵌合型病毒样颗粒及在胰腺癌中的应用 |
| JP7385556B2 (ja) | 2017-09-01 | 2023-11-22 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｂｃｍａ抗原に特異的な免疫原性ペプチドおよびその使用 |
| EP3941938A1 (en) | 2019-03-06 | 2022-01-26 | Dana-Farber Cancer Institute, Inc. | T cell receptors specific to b-cell maturation antigen for treatment of cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| US5744144A (en) * | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| AUPM322393A0 (en) * | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
| DE19516673A1 (de) * | 1995-04-28 | 1996-10-31 | Gabriele Dr Pecher | Vakzine gegen Tumorerkrankungen |
| AUPN568095A0 (en) * | 1995-09-27 | 1995-10-26 | Austin Research Institute, The | Anti-Galalpha(1,3)Gal antibody binding peptides |
| JP2001510440A (ja) * | 1996-03-20 | 2001-07-31 | スローン―ケタリング・インスティテュート・フォー・キャンサー・リサーチ | ムチン接合体ペプチドワクチン |
| US5744177A (en) * | 1996-06-11 | 1998-04-28 | Lin; Rong-Teng | Injection molding assembly |
-
1999
- 1999-12-22 GB GBGB9930359.6A patent/GB9930359D0/en not_active Ceased
-
2000
- 2000-12-20 CZ CZ20022192A patent/CZ20022192A3/cs unknown
- 2000-12-20 PL PL00356697A patent/PL356697A1/xx not_active Application Discontinuation
- 2000-12-20 JP JP2001547137A patent/JP2003517845A/ja active Pending
- 2000-12-20 IL IL15028500A patent/IL150285A0/xx unknown
- 2000-12-20 KR KR1020027008063A patent/KR20020073149A/ko not_active Withdrawn
- 2000-12-20 BR BR0016672-3A patent/BR0016672A/pt not_active IP Right Cessation
- 2000-12-20 WO PCT/GB2000/004906 patent/WO2001046228A2/en not_active Ceased
- 2000-12-20 MX MXPA02006313A patent/MXPA02006313A/es unknown
- 2000-12-20 EP EP00985646A patent/EP1240317B1/en not_active Expired - Lifetime
- 2000-12-20 ES ES00985646T patent/ES2282156T3/es not_active Expired - Lifetime
- 2000-12-20 DE DE60033690T patent/DE60033690T2/de not_active Expired - Lifetime
- 2000-12-20 AU AU22049/01A patent/AU2204901A/en not_active Abandoned
- 2000-12-20 CN CN00819076A patent/CN1434862A/zh active Pending
- 2000-12-20 HU HU0203848A patent/HUP0203848A3/hu unknown
- 2000-12-20 CA CA002395208A patent/CA2395208A1/en not_active Abandoned
- 2000-12-20 NZ NZ519732A patent/NZ519732A/en unknown
- 2000-12-20 US US10/168,873 patent/US20030133909A1/en not_active Abandoned
- 2000-12-20 AT AT00985646T patent/ATE355365T1/de not_active IP Right Cessation
-
2002
- 2002-06-20 ZA ZA200204987A patent/ZA200204987B/en unknown
- 2002-06-21 NO NO20023010A patent/NO20023010L/no not_active Application Discontinuation
-
2006
- 2006-11-02 US US11/555,793 patent/US20070269451A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02006313A (es) | 2002-11-29 |
| US20030133909A1 (en) | 2003-07-17 |
| IL150285A0 (en) | 2002-12-01 |
| CA2395208A1 (en) | 2001-06-28 |
| HUP0203848A2 (hu) | 2003-03-28 |
| JP2003517845A (ja) | 2003-06-03 |
| ATE355365T1 (de) | 2006-03-15 |
| HUP0203848A3 (en) | 2004-07-28 |
| PL356697A1 (en) | 2004-06-28 |
| WO2001046228A3 (en) | 2002-01-17 |
| EP1240317B1 (en) | 2007-02-28 |
| NO20023010D0 (no) | 2002-06-21 |
| NO20023010L (no) | 2002-08-06 |
| CZ20022192A3 (cs) | 2002-11-13 |
| ES2282156T3 (es) | 2007-10-16 |
| DE60033690D1 (de) | 2007-04-12 |
| CN1434862A (zh) | 2003-08-06 |
| GB9930359D0 (en) | 2000-02-09 |
| NZ519732A (en) | 2004-03-26 |
| KR20020073149A (ko) | 2002-09-19 |
| AU2204901A (en) | 2001-07-03 |
| US20070269451A1 (en) | 2007-11-22 |
| EP1240317A2 (en) | 2002-09-18 |
| ZA200204987B (en) | 2003-09-22 |
| DE60033690T2 (de) | 2007-11-08 |
| WO2001046228A2 (en) | 2001-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |