BR0017261A - Métodos para isolamento de uma bioentidade alvo de uma amostra biológica e de células de tumor com densidade de antìgeno baixa e, kits para inibir a agregação endógena de partìculas magnéticas coloidais no processamento de material biológico e, para isolamento de células de tumor de densidade de antìgeno baixa de uma amostra biológica com agregação ontrolada de partìculas magnéticas coloidais - Google Patents

Métodos para isolamento de uma bioentidade alvo de uma amostra biológica e de células de tumor com densidade de antìgeno baixa e, kits para inibir a agregação endógena de partìculas magnéticas coloidais no processamento de material biológico e, para isolamento de células de tumor de densidade de antìgeno baixa de uma amostra biológica com agregação ontrolada de partìculas magnéticas coloidais

Info

Publication number
BR0017261A
BR0017261A BR0017261-8A BR0017261A BR0017261A BR 0017261 A BR0017261 A BR 0017261A BR 0017261 A BR0017261 A BR 0017261A BR 0017261 A BR0017261 A BR 0017261A
Authority
BR
Brazil
Prior art keywords
magnetic particles
biological sample
tumor cells
antigen density
aggregation
Prior art date
Application number
BR0017261-8A
Other languages
English (en)
Inventor
Paul A Liberti
Galla Chandra Rao
Leon W M M Terstappen
Original Assignee
Immunivest Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21741591&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0017261(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunivest Corp filed Critical Immunivest Corp
Publication of BR0017261A publication Critical patent/BR0017261A/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

"MéTODOS PARA ISOLAMENTO DE UMA BIOENTIDADE ALVO DE UMA AMOSTRA BIOLóGICA E DE CéLULAS DE TUMOR COM DENSIDADE DE ANTìGENO BAIXA, E, KITS PARA INIBIR A AGREGAçãO ENDóGENA DE PARTìCULAS MAGNéTICAS COLOIDAIS NO PROCESSAMENTO DE MATERIAL BIOLóGICO E, PARA ISOLAMENTO DE CéLULAS DE TUMOR DE DENSIDADE DE ANTìGENO BAIXA DE UMA AMOSTRA BIOLóGICA COM AGREGAçãO CONTROLADA DE PARTìCULAS MAGNéTICAS COLOIDAIS". Composições e métodos são divulgados que realçam a observação microscópica e análise de entidades biológicas tais como células, bactérias e vírus através de eliminação de agrupamentos magnéticos interferentes criados através de agregados naturalmente ocorrentes de partículas magnéticas coloidais. Adicionalmente os meios para realçar significantemente o isolamento magnético de células alvo de baixa densidade de antígeno de amostras biológicas são divulgados.
BR0017261-8A 2000-07-14 2000-07-14 Métodos para isolamento de uma bioentidade alvo de uma amostra biológica e de células de tumor com densidade de antìgeno baixa e, kits para inibir a agregação endógena de partìculas magnéticas coloidais no processamento de material biológico e, para isolamento de células de tumor de densidade de antìgeno baixa de uma amostra biológica com agregação ontrolada de partìculas magnéticas coloidais BR0017261A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/019171 WO2002006790A1 (en) 2000-07-14 2000-07-14 Increased separation efficiency via controlled aggregation of magnetic nanoparticles

Publications (1)

Publication Number Publication Date
BR0017261A true BR0017261A (pt) 2003-07-29

Family

ID=21741591

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0017261-8A BR0017261A (pt) 2000-07-14 2000-07-14 Métodos para isolamento de uma bioentidade alvo de uma amostra biológica e de células de tumor com densidade de antìgeno baixa e, kits para inibir a agregação endógena de partìculas magnéticas coloidais no processamento de material biológico e, para isolamento de células de tumor de densidade de antìgeno baixa de uma amostra biológica com agregação ontrolada de partìculas magnéticas coloidais

Country Status (8)

Country Link
EP (1) EP1311820B1 (pt)
JP (1) JP4663957B2 (pt)
CN (1) CN1454313A (pt)
AU (2) AU6345600A (pt)
BR (1) BR0017261A (pt)
CA (1) CA2416277C (pt)
DK (1) DK1311820T3 (pt)
WO (1) WO2002006790A1 (pt)

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DE10239999A1 (de) * 2002-08-27 2004-03-04 Röhm GmbH & Co. KG Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen
EP1624306A4 (en) * 2003-04-30 2008-12-24 Chengdu Kuachang Medical Ind L DEVICE CONTAINING THE NANOSTRUCTURES USED FOR SEPARATION OR ANALYSIS AND MANUFACTURE AND APPLICATION THEREOF
CN100334105C (zh) * 2003-12-12 2007-08-29 上海交通大学 纳米磁性颗粒分离纯化链酶亲合素的方法
AU2007353319A1 (en) * 2006-11-15 2008-11-20 Invitrogen Dynal As Methods for reversibly binding a biotin compound to a support
US20100144005A1 (en) * 2007-04-26 2010-06-10 Bin Kingombe Cesar G I Process for isolating microorganisms from samples and system, apparatus and compositions therefor
US8071395B2 (en) 2007-12-12 2011-12-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for magnetic separation of cells
JP5080434B2 (ja) * 2008-12-05 2012-11-21 ベリデックス・リミテッド・ライアビリティ・カンパニー 生物学的試料から標的生体部分を単離する方法およびそのためのキット
US9494557B2 (en) 2011-04-05 2016-11-15 Purdue Research Foundation Micro-fluidic system using micro-apertures for high throughput detection of cells
US10732178B2 (en) * 2013-01-29 2020-08-04 Bio-Rad Haifa Ltd. Detection assays employing magnetic nanoparticles
US9409148B2 (en) 2013-08-08 2016-08-09 Uchicago Argonne, Llc Compositions and methods for direct capture of organic materials from process streams
EP3434372B1 (en) * 2014-11-19 2020-02-26 F. Hoffmann-La Roche AG Particle mixing
US9625385B2 (en) * 2015-02-24 2017-04-18 Tokitae Llc Photothermal spectroscopy systems for offset synchronous testing of flow assays and methods of using same
CN107532149A (zh) * 2015-02-26 2018-01-02 生物磁溶液有限公司 通过各成分基本上同时孵育和通用载体以分离细胞
JP6716683B2 (ja) 2015-05-01 2020-07-01 バイオレジェンド，インコーポレイテッド 安定なナノ磁性粒子分散
WO2017053630A1 (en) * 2015-09-22 2017-03-30 Purdue Research Foundation Centrifuge-free isolation and detection of rare cells
CN105259343A (zh) * 2015-11-10 2016-01-20 江南大学 一种从单链抗体库中筛选抗小分子半抗原单链抗体的方法
CN105466896A (zh) * 2015-11-23 2016-04-06 江南大学 核酸适配体功能化磁纳米颗粒分离富集-激光诱导荧光检测金黄色葡萄球菌
WO2017190117A1 (en) 2016-04-30 2017-11-02 BioLegend, Inc. Compositions and methods for performing magnetibuoyant separations
CN109991410B (zh) * 2017-12-29 2022-07-05 上海白泽医学检验所有限公司 一种含抗cd45单抗的组合物及其使用方法
US12140526B2 (en) 2018-02-28 2024-11-12 Juno Therapeutics, Inc. Methods for detecting particles present in a cell composition
US11262352B2 (en) 2018-07-20 2022-03-01 Cornell University Magnetic separation of biological entities from fluid sample
WO2020080833A1 (ko) 2018-10-17 2020-04-23 주식회사 이지다이아텍 생체물질 검출용 미세 입자 및 이를 이용한 생체물질 검출방법
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CN115667928B (zh) * 2020-05-29 2025-07-18 新加坡国立大学 用于生物分子、生物细胞器、生物颗粒、细胞和微生物检测的方法、系统、制品、试剂盒及其用途
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Also Published As

Publication number Publication date
EP1311820B1 (en) 2015-02-11
AU6345600A (en) 2002-01-30
AU2000263456B2 (en) 2006-07-20
CA2416277C (en) 2010-10-26
DK1311820T3 (en) 2015-04-07
CN1454313A (zh) 2003-11-05
EP1311820A1 (en) 2003-05-21
EP1311820A4 (en) 2004-06-23
CA2416277A1 (en) 2002-01-24
WO2002006790A1 (en) 2002-01-24
JP2004504129A (ja) 2004-02-12
JP4663957B2 (ja) 2011-04-06

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.