BR0109891A - Composição farmaceutica contendo derivado de camptotecina e substância de ajuste de ph - Google Patents
Composição farmaceutica contendo derivado de camptotecina e substância de ajuste de phInfo
- Publication number
- BR0109891A BR0109891A BR0109891-8A BR0109891A BR0109891A BR 0109891 A BR0109891 A BR 0109891A BR 0109891 A BR0109891 A BR 0109891A BR 0109891 A BR0109891 A BR 0109891A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- composition containing
- camptothecin derivative
- adjusting substance
- containing camptothecin
- Prior art date
Links
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- KLWPJMFMVPTNCC-UHFFFAOYSA-N Camptothecin Natural products CCC1(O)C(=O)OCC2=C1C=C3C4Nc5ccccc5C=C4CN3C2=O KLWPJMFMVPTNCC-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940127093 camptothecin Drugs 0.000 abstract 1
- VSJKWCGYPAHWDS-UHFFFAOYSA-N dl-camptothecin Natural products C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)C5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-UHFFFAOYSA-N 0.000 abstract 1
- 238000010979 pH adjustment Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
"COMPOSIçãO FARMACêUTICA CONTENDO DERIVADO DE CAMPTOTECINA E SUBSTâNCIA DE AJUSTE DE PH". Trata-se de uma preparação farmacêutica que assegura estabilidade e solubilidade de um derivado camptotecina hexacíclico preparado pela adição de um anel tendo um grupo solúvel em água a camptotecina, onde uma substância de ajuste de pH e, como ocasião demanda, um açúcar ou um álcool de açúcar são adicionados ao derivado de camptotecina hexacíclico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000111919 | 2000-04-07 | ||
| JP2000169082 | 2000-06-01 | ||
| PCT/JP2001/002982 WO2001076603A1 (en) | 2000-04-07 | 2001-04-06 | Medicinal compositions containing camptothecin derivative and ph regulating agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109891A true BR0109891A (pt) | 2002-12-31 |
Family
ID=26590030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0109891-8A BR0109891A (pt) | 2000-04-07 | 2001-04-06 | Composição farmaceutica contendo derivado de camptotecina e substância de ajuste de ph |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20030109460A1 (pt) |
| EP (1) | EP1310254A4 (pt) |
| KR (1) | KR20030009426A (pt) |
| CN (1) | CN1433310A (pt) |
| AR (1) | AR030207A1 (pt) |
| AU (1) | AU4874301A (pt) |
| BR (1) | BR0109891A (pt) |
| CA (1) | CA2405453A1 (pt) |
| MX (1) | MXPA02009901A (pt) |
| NO (1) | NO20024823L (pt) |
| RU (1) | RU2002126558A (pt) |
| WO (1) | WO2001076603A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200306314A (en) * | 2002-04-16 | 2003-11-16 | Tanabe Seiyaku Co | Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation |
| JP2006151808A (ja) * | 2002-12-24 | 2006-06-15 | Dai Ichi Seiyaku Co Ltd | 抗菌性水性製剤 |
| TW200727900A (en) * | 2005-07-27 | 2007-08-01 | Yakult Honsha Kk | Aqueous solution preparation containing camptothecins |
| CN104524588A (zh) * | 2014-12-05 | 2015-04-22 | 天津键凯科技有限公司 | 一种聚乙二醇修饰的喜树碱类衍生物的药物组合物及其制备方法 |
| HUE060364T2 (hu) | 2019-03-29 | 2023-02-28 | Medimmune Ltd | Vegyületek és konjugátumaik |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| TW202320858A (zh) | 2021-07-19 | 2023-06-01 | 美商薩諾管理公司 | 免疫接合物及方法 |
| CN118496288B (zh) * | 2023-02-06 | 2025-01-10 | 中国科学院微生物研究所 | 一种糖基化喜树碱类化合物Gly-CPTR及其制药用途、药物或前药及制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5693760A (en) * | 1988-04-14 | 1997-12-02 | Incyte Pharmaceuticals, Inc. | Method of causing selective immunosuppression using HL-60 related lectins |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| JPH0770195A (ja) * | 1993-08-23 | 1995-03-14 | Yutaka Mizushima | 糖修飾インターフェロン |
| US6504029B1 (en) * | 1995-04-10 | 2003-01-07 | Daiichi Pharmaceutical Co., Ltd. | Condensed-hexacyclic compounds and a process therefor |
| JP2000044567A (ja) * | 1998-07-29 | 2000-02-15 | Dai Ichi Seiyaku Co Ltd | 六環性化合物 |
-
2001
- 2001-04-05 AR ARP010101614A patent/AR030207A1/es unknown
- 2001-04-06 RU RU2002126558/15A patent/RU2002126558A/ru not_active Application Discontinuation
- 2001-04-06 CA CA002405453A patent/CA2405453A1/en not_active Abandoned
- 2001-04-06 KR KR1020027013406A patent/KR20030009426A/ko not_active Withdrawn
- 2001-04-06 CN CN01810586A patent/CN1433310A/zh active Pending
- 2001-04-06 WO PCT/JP2001/002982 patent/WO2001076603A1/ja not_active Ceased
- 2001-04-06 EP EP01921793A patent/EP1310254A4/en not_active Withdrawn
- 2001-04-06 AU AU48743/01A patent/AU4874301A/en not_active Abandoned
- 2001-04-06 BR BR0109891-8A patent/BR0109891A/pt not_active IP Right Cessation
- 2001-04-06 US US10/240,784 patent/US20030109460A1/en not_active Abandoned
- 2001-04-06 MX MXPA02009901A patent/MXPA02009901A/es unknown
-
2002
- 2002-10-04 NO NO20024823A patent/NO20024823L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20024823D0 (no) | 2002-10-04 |
| AU4874301A (en) | 2001-10-23 |
| WO2001076603A1 (en) | 2001-10-18 |
| EP1310254A4 (en) | 2006-05-10 |
| KR20030009426A (ko) | 2003-01-29 |
| EP1310254A1 (en) | 2003-05-14 |
| CN1433310A (zh) | 2003-07-30 |
| CA2405453A1 (en) | 2002-10-03 |
| NO20024823L (no) | 2002-12-06 |
| AR030207A1 (es) | 2003-08-13 |
| MXPA02009901A (es) | 2003-05-27 |
| US20030109460A1 (en) | 2003-06-12 |
| RU2002126558A (ru) | 2004-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO DA RPI 2016 DE 25/08/2009. |