BR0109934A - Preparação e prevenção de diarréia de ácido biliar - Google Patents
Preparação e prevenção de diarréia de ácido biliarInfo
- Publication number
- BR0109934A BR0109934A BR0109934-5A BR0109934A BR0109934A BR 0109934 A BR0109934 A BR 0109934A BR 0109934 A BR0109934 A BR 0109934A BR 0109934 A BR0109934 A BR 0109934A
- Authority
- BR
- Brazil
- Prior art keywords
- bile acid
- prevention
- preparation
- acid diarrhea
- diarrhea
- Prior art date
Links
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 title abstract 6
- 239000003613 bile acid Substances 0.000 title abstract 6
- 206010012735 Diarrhoea Diseases 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 4
- 230000002265 prevention Effects 0.000 title abstract 4
- 239000003463 adsorbent Substances 0.000 abstract 1
- 239000003524 antilipemic agent Substances 0.000 abstract 1
- 210000004534 cecum Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 210000000813 small intestine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"PREPARAçãO E PREVENçãO DE DIARRéIA DE áCIDO BILIAR". Preparações para a prevenção de diarréia de ácido biliar que compreendem conter um adsorvente de ácido biliar com um polímero a fim de permitir a sua liberação ao redor de uma área desde a parte inferior do intestino delgado até o ceco; e composições farmacêuticas compreendendo uma combinação de inibidores de reabsorção de ácido biliar com as preparações acima para a prevenção de diarréia de ácido biliar (por exemplo, agente anti-hiperlipidêmico.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000107431 | 2000-04-10 | ||
| PCT/JP2001/002618 WO2001076635A1 (en) | 2000-04-10 | 2001-03-29 | Preparations for preventing bile acid diarrhea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109934A true BR0109934A (pt) | 2003-05-27 |
Family
ID=18620426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0109934-5A BR0109934A (pt) | 2000-04-10 | 2001-03-29 | Preparação e prevenção de diarréia de ácido biliar |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20030124088A1 (pt) |
| EP (1) | EP1273307A1 (pt) |
| KR (1) | KR20030008367A (pt) |
| CN (1) | CN1198653C (pt) |
| AU (2) | AU4461101A (pt) |
| BR (1) | BR0109934A (pt) |
| CA (1) | CA2404422A1 (pt) |
| MX (1) | MXPA02009897A (pt) |
| TW (1) | TWI241195B (pt) |
| WO (1) | WO2001076635A1 (pt) |
| ZA (1) | ZA200208310B (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2637020T3 (es) * | 2001-04-18 | 2017-10-10 | Genzyme Corporation | Uso de polímero de amina para reducir la glucosa sérica |
| JP2007517047A (ja) * | 2003-12-31 | 2007-06-28 | ジェンザイム・コーポレーション | 腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子 |
| NZ595865A (en) * | 2005-10-07 | 2011-12-22 | Colocaps Pty Ltd | Preparation for the Treatment of Diarrhoea comprising a bulking agent and diphenoxylate (ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate) |
| EP1949093A2 (en) * | 2005-10-11 | 2008-07-30 | Alvine Pharmaceuticals, Inc. | Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides |
| EP3777864A1 (en) | 2010-11-04 | 2021-02-17 | Albireo AB | Ibat inhibitors for the treatment of liver diseases |
| WO2015199147A1 (ja) | 2014-06-25 | 2015-12-30 | 味の素株式会社 | 固形製剤及びその着色防止又は着色低減方法 |
| EP3012252A1 (en) | 2014-10-24 | 2016-04-27 | Ferring BV | Crystal modifications of elobixibat |
| US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
| CN108601744B (zh) * | 2016-02-09 | 2022-01-04 | 阿尔比里奥公司 | 口服考来烯胺制剂及其用途 |
| US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| WO2017138878A1 (en) | 2016-02-09 | 2017-08-17 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| EP3413875B1 (en) | 2016-02-09 | 2020-01-29 | Albireo AB | Cholestyramine pellets and methods for preparation thereof |
| WO2019032027A1 (en) | 2017-08-09 | 2019-02-14 | Albireo Ab | CHOLESTYRAMINE TABLETS, ORAL FORMULATIONS OF CHOLESTYRAMINE AND THEIR USE |
| JP2020530448A (ja) * | 2017-08-09 | 2020-10-22 | アルビレオ・アクチボラグ | コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用 |
| CA3089742A1 (en) * | 2018-01-30 | 2019-08-08 | Pharmascience Inc. | Cholestyramine formulations and methods of use |
| US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| IL279464B2 (en) | 2018-06-20 | 2025-12-01 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11590161B2 (en) | 2018-08-13 | 2023-02-28 | Viscera Labs, Inc. | Therapeutic composition and methods |
| US11524029B2 (en) | 2018-08-13 | 2022-12-13 | Viscera Labs, Inc. | Therapeutic composition and methods |
| KR102447441B1 (ko) | 2019-04-15 | 2022-09-27 | (주)제테마 | 보툴리눔 독소의 정제방법 |
| KR102516204B1 (ko) | 2019-04-15 | 2023-03-30 | (주)제테마 | 보툴리눔 독소의 정제방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914401A (en) * | 1971-10-12 | 1975-10-21 | Lilly Co Eli | Enteric compositions |
| GB1557082A (en) * | 1977-01-25 | 1979-12-05 | Fisons Ltd | Pharmaceutical mixture containing an antiinflammatory |
| ZA876640B (en) * | 1986-09-26 | 1988-03-08 | Warner-Lambert Company | Treated lipid regulator |
| US4814354A (en) * | 1986-09-26 | 1989-03-21 | Warner-Lambert Company | Lipid regulating agents |
| JP2773959B2 (ja) * | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| ATE175954T1 (de) * | 1991-10-17 | 1999-02-15 | Shionogi & Co | Verfahren zum herstellen von lignin-analoga und ausgangsprodukte dafür |
| SG80553A1 (en) * | 1995-07-20 | 2001-05-22 | Tanabe Seiyaku Co | Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract |
| TW438608B (en) * | 1995-08-02 | 2001-06-07 | Hisamitsu Pharmaceutical Co | A tablet containing anion exchange resin |
| JPH09241206A (ja) * | 1996-03-01 | 1997-09-16 | Shionogi & Co Ltd | リグナン系化合物 |
-
2001
- 2001-03-28 TW TW090107353A patent/TWI241195B/zh not_active IP Right Cessation
- 2001-03-29 MX MXPA02009897A patent/MXPA02009897A/es unknown
- 2001-03-29 US US10/257,031 patent/US20030124088A1/en not_active Abandoned
- 2001-03-29 KR KR1020027013471A patent/KR20030008367A/ko not_active Withdrawn
- 2001-03-29 BR BR0109934-5A patent/BR0109934A/pt not_active IP Right Cessation
- 2001-03-29 CN CNB01807572XA patent/CN1198653C/zh not_active Expired - Fee Related
- 2001-03-29 AU AU4461101A patent/AU4461101A/xx active Pending
- 2001-03-29 CA CA002404422A patent/CA2404422A1/en not_active Abandoned
- 2001-03-29 WO PCT/JP2001/002618 patent/WO2001076635A1/ja not_active Ceased
- 2001-03-29 AU AU2001244611A patent/AU2001244611B2/en not_active Expired - Fee Related
- 2001-03-29 EP EP01917586A patent/EP1273307A1/en not_active Withdrawn
-
2002
- 2002-10-15 ZA ZA200208310A patent/ZA200208310B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1422164A (zh) | 2003-06-04 |
| AU2001244611B2 (en) | 2006-02-16 |
| KR20030008367A (ko) | 2003-01-25 |
| CN1198653C (zh) | 2005-04-27 |
| WO2001076635A1 (en) | 2001-10-18 |
| US20030124088A1 (en) | 2003-07-03 |
| AU4461101A (en) | 2001-10-23 |
| TWI241195B (en) | 2005-10-11 |
| EP1273307A1 (en) | 2003-01-08 |
| CA2404422A1 (en) | 2002-09-26 |
| ZA200208310B (en) | 2003-10-15 |
| MXPA02009897A (es) | 2003-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO DA RPI 2016 DE 25/08/2009. |