BR0212574A - Método de purificação de polipeptìdeo - Google Patents
Método de purificação de polipeptìdeoInfo
- Publication number
- BR0212574A BR0212574A BR0212574-9A BR0212574A BR0212574A BR 0212574 A BR0212574 A BR 0212574A BR 0212574 A BR0212574 A BR 0212574A BR 0212574 A BR0212574 A BR 0212574A
- Authority
- BR
- Brazil
- Prior art keywords
- tyrosine kinase
- kinase receptor
- polypeptide
- purification method
- expressed
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 7
- 238000000746 purification Methods 0.000 title abstract 3
- 102000004278 Receptor Protein-Tyrosine Kinases Human genes 0.000 abstract 5
- 108090000873 Receptor Protein-Tyrosine Kinases Proteins 0.000 abstract 5
- 238000000926 separation method Methods 0.000 abstract 2
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"MéTODO DE PURIFICAçãO DE POLIPEPTìDEO". A presente invenção refere-se a um método de purificação, particularmente para purificar polipeptídeos relacionados ao receptor de cinase de tirosina e aos produtos feitos pelo método. O método compreende um método de produzir polipeptídeos relacionados ao receptor de cinase de tirosina, o método compreendendo expressar o polipeptídeo relacionado ao receptor de cinase de tirosina em um sistema de expressão recombinante e separar o polipeptídeo relacionado ao receptor de cinase de tirosina, monomérico, expresso, da(s) forma(s) multimérica(s) do polipeptídeo, expresso, em uma etapa de separação, a etapa de separação permitindo a redobragem do polipeptídeo relacionado ao receptor de cinase de tirosina, expresso, em uma forma biologicamente ativa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0122400.5A GB0122400D0 (en) | 2001-09-17 | 2001-09-17 | Polypeptide purification method |
| PCT/GB2002/004214 WO2003025016A2 (en) | 2001-09-17 | 2002-09-17 | Trk polypeptide purification method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0212574A true BR0212574A (pt) | 2004-10-13 |
Family
ID=9922207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0212574-9A BR0212574A (pt) | 2001-09-17 | 2002-09-17 | Método de purificação de polipeptìdeo |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20050070690A1 (pt) |
| EP (1) | EP1427751A2 (pt) |
| JP (1) | JP2005514914A (pt) |
| KR (1) | KR20040047836A (pt) |
| CN (1) | CN1564827A (pt) |
| AU (1) | AU2002324207B2 (pt) |
| BR (1) | BR0212574A (pt) |
| CA (1) | CA2460706A1 (pt) |
| GB (1) | GB0122400D0 (pt) |
| HR (1) | HRPK20040339B3 (pt) |
| HU (1) | HUP0400981A3 (pt) |
| IL (1) | IL160912A0 (pt) |
| IS (1) | IS7183A (pt) |
| MX (1) | MXPA04002373A (pt) |
| NO (1) | NO20041563L (pt) |
| NZ (1) | NZ532331A (pt) |
| PL (1) | PL369451A1 (pt) |
| RU (1) | RU2004110939A (pt) |
| WO (1) | WO2003025016A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030096753A1 (en) * | 1998-04-09 | 2003-05-22 | Robertson Alan George Simpson | Therapeutic agent |
| GB9807781D0 (en) * | 1998-04-09 | 1998-06-10 | Univ Bristol | Therapeutic agent |
| GB0020504D0 (en) * | 2000-08-18 | 2000-10-11 | Univ Bristol | Therapeutic method |
| GB201308738D0 (en) * | 2013-05-15 | 2013-06-26 | Polytherics Ltd | Novel polymer conjugates |
| JP2020026397A (ja) * | 2018-08-09 | 2020-02-20 | 国立大学法人 岡山大学 | ＴｒｋＢアンタゴニストを含む医薬組成物 |
| WO2025062271A1 (en) * | 2023-09-19 | 2025-03-27 | Signorile Pietro Giulio | Antibodies against endometriosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK166763C (da) * | 1983-03-16 | 1993-07-12 | Immuno Ag | Immunoglobulin-g-holdig fraktion |
| US5877016A (en) * | 1994-03-18 | 1999-03-02 | Genentech, Inc. | Human trk receptors and neurotrophic factor inhibitors |
| US5844092A (en) * | 1994-03-18 | 1998-12-01 | Genentech, Inc. | Human TRK receptors and neurotrophic factor inhibitors |
| CA2271950A1 (en) * | 1996-11-22 | 1998-05-28 | Sugen, Inc. | Receptor tyrosine kinase genes |
| US20030096753A1 (en) * | 1998-04-09 | 2003-05-22 | Robertson Alan George Simpson | Therapeutic agent |
| GB9807781D0 (en) * | 1998-04-09 | 1998-06-10 | Univ Bristol | Therapeutic agent |
| GB0020504D0 (en) * | 2000-08-18 | 2000-10-11 | Univ Bristol | Therapeutic method |
-
2001
- 2001-09-17 GB GBGB0122400.5A patent/GB0122400D0/en not_active Ceased
-
2002
- 2002-09-17 CA CA002460706A patent/CA2460706A1/en not_active Abandoned
- 2002-09-17 NZ NZ532331A patent/NZ532331A/en unknown
- 2002-09-17 WO PCT/GB2002/004214 patent/WO2003025016A2/en not_active Ceased
- 2002-09-17 AU AU2002324207A patent/AU2002324207B2/en not_active Ceased
- 2002-09-17 CN CNA028196554A patent/CN1564827A/zh active Pending
- 2002-09-17 HR HR20040339A patent/HRPK20040339B3/xx not_active IP Right Cessation
- 2002-09-17 IL IL16091202A patent/IL160912A0/xx unknown
- 2002-09-17 MX MXPA04002373A patent/MXPA04002373A/es not_active Application Discontinuation
- 2002-09-17 RU RU2004110939/13A patent/RU2004110939A/ru not_active Application Discontinuation
- 2002-09-17 BR BR0212574-9A patent/BR0212574A/pt not_active IP Right Cessation
- 2002-09-17 JP JP2003528861A patent/JP2005514914A/ja active Pending
- 2002-09-17 US US10/489,739 patent/US20050070690A1/en not_active Abandoned
- 2002-09-17 EP EP02758626A patent/EP1427751A2/en not_active Withdrawn
- 2002-09-17 PL PL02369451A patent/PL369451A1/xx not_active Application Discontinuation
- 2002-09-17 KR KR10-2004-7003935A patent/KR20040047836A/ko not_active Ceased
- 2002-09-17 HU HU0400981A patent/HUP0400981A3/hu unknown
-
2004
- 2004-03-16 IS IS7183A patent/IS7183A/is unknown
- 2004-04-16 NO NO20041563A patent/NO20041563L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0400981A3 (en) | 2006-01-30 |
| GB0122400D0 (en) | 2001-11-07 |
| MXPA04002373A (es) | 2004-11-22 |
| IL160912A0 (en) | 2004-08-31 |
| EP1427751A2 (en) | 2004-06-16 |
| IS7183A (is) | 2004-03-16 |
| HUP0400981A2 (hu) | 2005-02-28 |
| NO20041563L (no) | 2004-04-16 |
| WO2003025016A3 (en) | 2003-07-03 |
| AU2002324207B2 (en) | 2007-10-18 |
| CN1564827A (zh) | 2005-01-12 |
| KR20040047836A (ko) | 2004-06-05 |
| CA2460706A1 (en) | 2003-03-27 |
| PL369451A1 (en) | 2005-04-18 |
| HRPK20040339B3 (en) | 2006-02-28 |
| RU2004110939A (ru) | 2005-05-27 |
| HRP20040339A2 (en) | 2004-10-31 |
| US20050070690A1 (en) | 2005-03-31 |
| JP2005514914A (ja) | 2005-05-26 |
| NZ532331A (en) | 2005-10-28 |
| WO2003025016A2 (en) | 2003-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010. |