BR0213249A - Dispositivo e eletrodo para a aplicação ocular de um princìpio ativo - Google Patents

Dispositivo e eletrodo para a aplicação ocular de um princìpio ativo

Info

Publication number
BR0213249A
BR0213249A BR0213249-4A BR0213249A BR0213249A BR 0213249 A BR0213249 A BR 0213249A BR 0213249 A BR0213249 A BR 0213249A BR 0213249 A BR0213249 A BR 0213249A
Authority
BR
Brazil
Prior art keywords
electrode
active principle
ocular application
eye
application
Prior art date
Application number
BR0213249-4A
Other languages
English (en)
Inventor
Francine Behar
Pierre Roy
Original Assignee
Optis France S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optis France S A filed Critical Optis France S A
Publication of BR0213249A publication Critical patent/BR0213249A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"DISPOSITIVO E ELETRODO PARA A APLICAçãO OCULAR DE UM PRINCìPIO ATIVO". Dispositivo de aplicação ocular de um princípio ativo (1) que compreende um eletrodo principal (2) que possui uma camada isolante, uma camada de adesivo própria para ligar a camada isolante a uma camada condutora, caracterizado pelo fato de que o eletrodo principal apresenta uma zona (21, 22) própria para entrar em contato com uma pálpebra de um olho.
BR0213249-4A 2001-10-12 2002-10-11 Dispositivo e eletrodo para a aplicação ocular de um princìpio ativo BR0213249A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0113176A FR2830766B1 (fr) 2001-10-12 2001-10-12 Dispositif de delivrance de medicaments par iontophorese transpalpebrale
PCT/FR2002/003472 WO2003030989A2 (fr) 2001-10-12 2002-10-11 Dispositif de delivrance de medicaments par iontophorese transpalpebrale

Publications (1)

Publication Number Publication Date
BR0213249A true BR0213249A (pt) 2004-09-28

Family

ID=8868226

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0213249-4A BR0213249A (pt) 2001-10-12 2002-10-11 Dispositivo e eletrodo para a aplicação ocular de um princìpio ativo

Country Status (16)

Country Link
US (3) US7848800B2 (pt)
EP (1) EP1434622B1 (pt)
JP (1) JP4184275B2 (pt)
KR (1) KR20050035158A (pt)
AT (1) ATE358510T1 (pt)
BR (1) BR0213249A (pt)
CA (1) CA2463362C (pt)
CY (1) CY1106671T1 (pt)
DE (1) DE60219336T2 (pt)
DK (1) DK1434622T3 (pt)
ES (1) ES2283628T3 (pt)
FR (1) FR2830766B1 (pt)
IL (1) IL161298A0 (pt)
MX (1) MXPA04003438A (pt)
PT (1) PT1434622E (pt)
WO (1) WO2003030989A2 (pt)

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US20090088721A1 (en) * 2001-04-17 2009-04-02 Eyegate Pharma S.A.S. Enhanced retinal delivery of a nucleic acid through iontophoresis
US20050148530A1 (en) 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US7517864B2 (en) 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US9181551B2 (en) 2002-02-20 2015-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
FR2869531B1 (fr) * 2004-04-30 2006-07-14 Optis France Sa Sa Dispositif de iontophorese oculaire diminuant les irritations
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US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US20060089590A1 (en) * 2004-10-27 2006-04-27 John Higuchi Methods and devices for sustained in-vivo release of an active agent
US8755880B2 (en) 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
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US8634907B2 (en) 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
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JP2012520683A (ja) 2009-03-19 2012-09-10 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いた結合組織増殖因子(CTGF)遺伝子発現のRNA干渉媒介性阻害
WO2010107957A2 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010107958A1 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2411520A2 (en) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
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MX2011010072A (es) 2009-03-27 2011-10-06 Merck Sharp & Dohme Inhibicion mediada por interferencia de acido ribonucleico de la expresion del gen de la molecula de adhesion intercelular 1 usando acido nucleico corto de interferencia.
US20120010272A1 (en) 2009-03-27 2012-01-12 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Apoptosis Signal-Regulating Kinase 1 (ASK1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
WO2010111471A2 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
JP5937004B2 (ja) 2009-05-18 2016-06-22 ドーズ メディカル コーポレーションDose Medical Corporation 薬剤溶出眼内インプラント
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
JP2011018873A (ja) * 2009-05-22 2011-01-27 Sony Ericsson Mobilecommunications Japan Inc 電磁シールド方法および電磁シールド用フィルム
WO2012004416A2 (en) 2010-07-09 2012-01-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Treatment of a disease associated with retinal degenerative disorder
AU2011285909B2 (en) 2010-08-02 2016-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
EP2606134B1 (en) 2010-08-17 2019-04-10 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US9233997B2 (en) 2010-08-26 2016-01-12 Sirna Therapeutics, Inc. RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)
EP3766975A1 (en) 2010-10-29 2021-01-20 Sirna Therapeutics, Inc. Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
US9668915B2 (en) 2010-11-24 2017-06-06 Dose Medical Corporation Drug eluting ocular implant
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
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JP2016507484A (ja) 2012-12-06 2016-03-10 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. ジスルフィドマスキングプロドラッグ組成物および方法
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Also Published As

Publication number Publication date
ATE358510T1 (de) 2007-04-15
US8771256B2 (en) 2014-07-08
JP2005504612A (ja) 2005-02-17
US20140323947A1 (en) 2014-10-30
US9192512B2 (en) 2015-11-24
PT1434622E (pt) 2007-07-11
CY1106671T1 (el) 2012-05-23
DK1434622T3 (da) 2007-08-13
CA2463362A1 (fr) 2003-04-17
WO2003030989A2 (fr) 2003-04-17
MXPA04003438A (es) 2005-02-17
KR20050035158A (ko) 2005-04-15
EP1434622B1 (fr) 2007-04-04
US20040267188A1 (en) 2004-12-30
WO2003030989A3 (fr) 2003-10-30
CA2463362C (fr) 2011-04-19
IL161298A0 (en) 2004-09-27
ES2283628T3 (es) 2007-11-01
FR2830766A1 (fr) 2003-04-18
US20110098632A1 (en) 2011-04-28
JP4184275B2 (ja) 2008-11-19
US7848800B2 (en) 2010-12-07
DE60219336T2 (de) 2007-12-20
EP1434622A2 (fr) 2004-07-07
DE60219336D1 (de) 2007-05-16
FR2830766B1 (fr) 2004-03-12

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: EYEGATE PHARMA S.A. (FR)

Free format text: ALTERADO DE: OPTIS FRANCE S.A.

B25G Requested change of headquarter approved

Owner name: EYEGATE PHARMA S.A. (FR)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020060112495/RJ DE 25/07/2006.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements