BR0214806A - Composições farmacêuticos de 5,7,14-triazatetraciclo-{10.3.1.02,11.0,4,9]-hexadeca-2(1 1),3,5,7,9-penteno - Google Patents

Composições farmacêuticos de 5,7,14-triazatetraciclo-{10.3.1.02,11.0,4,9]-hexadeca-2(1 1),3,5,7,9-penteno

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Publication number
BR0214806A
BR0214806A BR0214806-4A BR0214806A BR0214806A BR 0214806 A BR0214806 A BR 0214806A BR 0214806 A BR0214806 A BR 0214806A BR 0214806 A BR0214806 A BR 0214806A
Authority
BR
Brazil
Prior art keywords
hexadeca
triazatetracyclo
pentene
pharmaceutical compositions
relates
Prior art date
Application number
BR0214806-4A
Other languages
English (en)
Inventor
Mary Tanya Am Ende
Michael Christopher Cafe
Scott Wendell Smith
Kenneth Craig Waterman
Sara Kristen Moses
Ernest Shing Quan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0214806A publication Critical patent/BR0214806A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Health & Medical Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
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  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract

"COMPOSIçõES FARMACêUTICAS DE 5,7,14-TRIAZATETRACICLO[10.3.1.0^ 2,11^.0^ 4,9^]-HEXADECA-2(11),3,5,7,9-PENTENO". A presente invenção refere-se a formas de distúrbio farmacêutica oral de liberação controlada (CR) de 5,8,14-triazatetraciclo[10.3.1.0^ 2,11^.0^ 4,9^]-hexadeca-2(11),3,5,7,9-penteno, 1, e seus sais farmaceuticamente aceitáveis, e métodos de os utilizar para reduzir o vício de nicotina ou ajudar na cessação ou diminuição do uso do tabaco enquanto reduzem a náusea como efeito adverso. A presente invenção também refere-se a uma composição de baixa distúrbio de liberação imediata (IR) tendo uma formulação estável com distribuição e potência de droga uniformes.
BR0214806-4A 2001-11-30 2002-11-04 Composições farmacêuticos de 5,7,14-triazatetraciclo-{10.3.1.02,11.0,4,9]-hexadeca-2(1 1),3,5,7,9-penteno BR0214806A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33465201P 2001-11-30 2001-11-30
PCT/IB2002/004612 WO2003045437A1 (en) 2001-11-30 2002-11-04 Pharmaceutical compositions of 5,7,14-triazatetracyclo[10.3.1.0(2,11).0(4,9)]-hexadeca-2(11)3,5,7,9-pentaene

Publications (1)

Publication Number Publication Date
BR0214806A true BR0214806A (pt) 2004-09-14

Family

ID=23308160

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214806-4A BR0214806A (pt) 2001-11-30 2002-11-04 Composições farmacêuticos de 5,7,14-triazatetraciclo-{10.3.1.02,11.0,4,9]-hexadeca-2(1 1),3,5,7,9-penteno

Country Status (31)

Country Link
US (1) US7771748B2 (pt)
EP (1) EP1448235B1 (pt)
JP (2) JP2005528330A (pt)
KR (2) KR20040063975A (pt)
CN (2) CN1864663A (pt)
AR (1) AR037592A1 (pt)
AT (1) ATE356625T1 (pt)
AU (1) AU2002351008B2 (pt)
BR (1) BR0214806A (pt)
CA (1) CA2467490C (pt)
DE (1) DE60218885T2 (pt)
DK (1) DK1448235T3 (pt)
ES (1) ES2282492T3 (pt)
GT (1) GT200200247A (pt)
IL (1) IL161857A0 (pt)
MX (1) MXPA04003807A (pt)
MY (1) MY130619A (pt)
NO (1) NO20042739L (pt)
NZ (1) NZ532435A (pt)
PA (1) PA8559501A1 (pt)
PE (1) PE20040121A1 (pt)
PL (1) PL208080B1 (pt)
PT (1) PT1448235E (pt)
PY (1) PY0228832A (pt)
RU (2) RU2272629C2 (pt)
SI (1) SI1448235T1 (pt)
SV (1) SV2004001418A (pt)
TW (1) TWI327471B (pt)
UY (1) UY27553A1 (pt)
WO (1) WO2003045437A1 (pt)
ZA (1) ZA200403068B (pt)

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ES2285233T3 (es) 2002-12-20 2007-11-16 Niconovum Ab Un material en particulas que contiene nicotina y celulosa microcristalina fisicamente y quimicamente estable.
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