BR0215717A - Monóxido de carbono como um biomarcador e agente terapêutico - Google Patents
Monóxido de carbono como um biomarcador e agente terapêuticoInfo
- Publication number
- BR0215717A BR0215717A BR0215717-9A BR0215717A BR0215717A BR 0215717 A BR0215717 A BR 0215717A BR 0215717 A BR0215717 A BR 0215717A BR 0215717 A BR0215717 A BR 0215717A
- Authority
- BR
- Brazil
- Prior art keywords
- diseases
- pulmonary
- biomarker
- therapeutic agent
- carbon monoxide
- Prior art date
Links
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title abstract 6
- 229910002091 carbon monoxide Inorganic materials 0.000 title abstract 6
- 239000000090 biomarker Substances 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 4
- 229940124597 therapeutic agent Drugs 0.000 title abstract 4
- 208000019693 Lung disease Diseases 0.000 abstract 3
- 210000004072 lung Anatomy 0.000 abstract 3
- 206010040047 Sepsis Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000036542 oxidative stress Effects 0.000 abstract 2
- 230000002685 pulmonary effect Effects 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000014644 Brain disease Diseases 0.000 abstract 1
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 208000004248 Familial Primary Pulmonary Hypertension Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000018262 Peripheral vascular disease Diseases 0.000 abstract 1
- 206010035664 Pneumonia Diseases 0.000 abstract 1
- 208000010378 Pulmonary Embolism Diseases 0.000 abstract 1
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 206010040070 Septic Shock Diseases 0.000 abstract 1
- 208000019229 Spleen disease Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000011341 adult acute respiratory distress syndrome Diseases 0.000 abstract 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 210000002216 heart Anatomy 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 210000000867 larynx Anatomy 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 208000019423 liver disease Diseases 0.000 abstract 1
- 210000003800 pharynx Anatomy 0.000 abstract 1
- 201000008312 primary pulmonary hypertension Diseases 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 208000037812 secondary pulmonary hypertension Diseases 0.000 abstract 1
- 230000036303 septic shock Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
- 208000027140 splenic disease Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2002/014836 WO2003094932A1 (en) | 2002-05-09 | 2002-05-09 | Carbon monoxide as a biomarker and therapeutic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0215717A true BR0215717A (pt) | 2005-02-22 |
Family
ID=29418043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0215717-9A BR0215717A (pt) | 2002-05-09 | 2002-05-09 | Monóxido de carbono como um biomarcador e agente terapêutico |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1501523A4 (sr) |
| JP (1) | JP2005532314A (sr) |
| KR (1) | KR20040106515A (sr) |
| CN (1) | CN1638781A (sr) |
| AU (1) | AU2002308676B2 (sr) |
| BR (1) | BR0215717A (sr) |
| CA (1) | CA2484770A1 (sr) |
| EA (1) | EA200401478A1 (sr) |
| MX (1) | MXPA04011113A (sr) |
| NO (1) | NO20044865L (sr) |
| RS (1) | RS96904A (sr) |
| UA (1) | UA84402C2 (sr) |
| WO (1) | WO2003094932A1 (sr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7678390B2 (en) | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| US7011854B2 (en) | 2002-02-04 | 2006-03-14 | Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof |
| WO2003088981A1 (en) | 2002-04-15 | 2003-10-30 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Methods of treating necrotizing enterocolitis |
| EA200401365A1 (ru) | 2002-04-15 | 2005-04-28 | Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн | Способы лечения илеуса |
| EA200401525A1 (ru) * | 2002-05-17 | 2006-06-30 | Йейл Юниверсити | Способы лечения гепатита (варианты ) |
| JP2005345242A (ja) * | 2004-06-02 | 2005-12-15 | Tohoku Univ | 肺癌の化学療法治療効果の評価方法 |
| JPWO2007073005A1 (ja) * | 2005-12-22 | 2009-06-04 | 学校法人慶應義塾 | メチル基転移反応調節物質 |
| EP2099439A2 (en) * | 2006-12-06 | 2009-09-16 | Alfama - Investigação E Desenvolvimento De Produto | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| JP2010094122A (ja) | 2008-06-12 | 2010-04-30 | Keio Gijuku | バイオマーカーとしてのマイクロrnaを用いた頭頸部腫瘍の診断・治療選択 |
| JP2012046470A (ja) * | 2010-08-30 | 2012-03-08 | Japan Science & Technology Agency | Gapdhの酵素活性阻害剤 |
| CN109925318A (zh) * | 2011-01-14 | 2019-06-25 | 洛杉矶儿童医院 | 用于治疗包括镰状细胞疾病的疾病的一氧化碳溶液 |
| US8927750B2 (en) | 2011-02-04 | 2015-01-06 | Universitaet Zu Koeln | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules |
| US9359197B2 (en) | 2011-03-24 | 2016-06-07 | Technion Research & Development Foundation Ltd. | Method of diagnosing, prognosing and monitoring parkinson's disease |
| US9163044B2 (en) | 2011-04-19 | 2015-10-20 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| ES2628634T3 (es) | 2011-07-21 | 2017-08-03 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas |
| WO2014165732A1 (en) | 2013-04-04 | 2014-10-09 | The Regents Of The University Of California | System and method for utilizing exhaled breath for monitoring inflammatory states |
| EP2868348A1 (en) * | 2013-11-04 | 2015-05-06 | Universität Zürich | CO-releasing compounds & formulations thereof useful for inducing mitochondrial biogenesis and tissue repair |
| TW201618795A (zh) * | 2014-04-15 | 2016-06-01 | 波泰里斯股份有限公司 | 用以改良器官功能及延長器官移植物壽命之系統及方法 |
| JP7161737B2 (ja) * | 2017-01-30 | 2022-10-27 | 哲也 石川 | 悪性腫瘍の検査方法 |
| WO2019235165A1 (ja) | 2018-06-08 | 2019-12-12 | 住友精化株式会社 | 炎症性消化器官疾患用組成物 |
| EP3804731A4 (en) * | 2018-06-08 | 2022-04-06 | Sumitomo Seika Chemicals Co., Ltd. | COMPOSITION FOR SKIN WOUNDS |
| US12370210B2 (en) * | 2019-06-06 | 2025-07-29 | The General Hospital Corporation | Carbon monoxide as a treatment for neurodegenerative disease |
| US20230346831A1 (en) * | 2020-07-16 | 2023-11-02 | Cornell University | Methods for treating metastatic cancer using low dose carbon monoxide |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5293875A (en) * | 1992-06-16 | 1994-03-15 | Natus Medical Incorporated | In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods |
| DE4421433C1 (de) * | 1994-06-18 | 1995-06-08 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung |
| DK0921807T3 (da) * | 1996-08-27 | 2004-03-15 | Messer Griesheim Gmbh | Hydrogenholdigt lægemiddel |
| CA2442457A1 (en) * | 2001-03-30 | 2002-10-10 | Roland Buelow | Carbon monoxide generating compounds for treatment of vascular, inflammatory and immune disorders |
-
2002
- 2002-05-09 BR BR0215717-9A patent/BR0215717A/pt not_active Application Discontinuation
- 2002-05-09 WO PCT/US2002/014836 patent/WO2003094932A1/en not_active Ceased
- 2002-05-09 EP EP02807413A patent/EP1501523A4/en not_active Withdrawn
- 2002-05-09 CN CNA028292995A patent/CN1638781A/zh active Pending
- 2002-05-09 MX MXPA04011113A patent/MXPA04011113A/es active IP Right Grant
- 2002-05-09 RS YUP-969/04A patent/RS96904A/sr unknown
- 2002-05-09 AU AU2002308676A patent/AU2002308676B2/en not_active Ceased
- 2002-05-09 EA EA200401478A patent/EA200401478A1/ru unknown
- 2002-05-09 UA UA20041210106A patent/UA84402C2/ru unknown
- 2002-05-09 JP JP2004503016A patent/JP2005532314A/ja active Pending
- 2002-05-09 CA CA002484770A patent/CA2484770A1/en not_active Abandoned
- 2002-05-09 KR KR10-2004-7018082A patent/KR20040106515A/ko not_active Ceased
-
2004
- 2004-11-09 NO NO20044865A patent/NO20044865L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1501523A1 (en) | 2005-02-02 |
| EP1501523A4 (en) | 2006-12-13 |
| AU2002308676A1 (en) | 2003-11-11 |
| JP2005532314A (ja) | 2005-10-27 |
| RS96904A (sr) | 2007-02-05 |
| CA2484770A1 (en) | 2003-11-20 |
| CN1638781A (zh) | 2005-07-13 |
| WO2003094932A1 (en) | 2003-11-20 |
| AU2002308676B2 (en) | 2009-06-11 |
| UA84402C2 (ru) | 2008-10-27 |
| NO20044865L (no) | 2004-12-07 |
| KR20040106515A (ko) | 2004-12-17 |
| MXPA04011113A (es) | 2005-02-14 |
| EA200401478A1 (ru) | 2005-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0215717A (pt) | Monóxido de carbono como um biomarcador e agente terapêutico | |
| AU2002316935A1 (en) | Novel pharmaceutical compositions based on anticholinergic agents, corticosteroids and betamimetic agents, for the treatment of inflammatory and/or obstructive respiratory tract diseases | |
| WO2007109118A3 (en) | RECOMBINANT HUMAN CC 10 (rhCC10) FOR TREATMENT OF RESPIRATORY DISORDERS | |
| WO2005041864A3 (en) | Combination of cyclooxygenase-2 inhibitor and phosphodiesterase 4 inhibitor and method | |
| NO20061254L (no) | Farmasoytiske blandinger | |
| MXPA02011311A (es) | Composicion novedosa. | |
| WO2003011274A3 (en) | Use of a pde4 inhibitor in combination with an anticholinergic agent for the treatment of pulmonary disease such as asthma | |
| AUPS057102A0 (en) | Compositions and methods for treatment of skin disorders | |
| DE60105807D1 (de) | Verfahren zur Herstellung einer stabilen pharmazeutischen Zusammensetzung enthaltend mikronisiertes Formoterol | |
| UA86400C2 (ru) | Применение эритропоэтина в низком дозировании для пациентов с дисфункцией эндотелиальных клеток-предшественников, сердечно-сосудистым фактором риска и повреждением конечного органа | |
| AU2006329199A8 (en) | Treatment of respiratory diseases | |
| SE9900834D0 (sv) | Novel combination | |
| IL180681A0 (en) | Pyridine derivatives, their preparation and use | |
| BR0015270A (pt) | Método e composições para tratamento de doenças pulmonares | |
| WO2001015672A3 (en) | Use of charged dextran as a mucoactive agent and methods and pharmaceutical compositions relating thereto | |
| WO2004005341A3 (en) | Full-length interferon gamma polypeptide variants | |
| WO2024173520A3 (en) | Rnai agents for inhibiting expression of thymic stromal lymphopoietin (tslp), compositions thereof, and methods of use | |
| EP1661892A4 (en) | CONDENS CYCLIC COMPOUND AND USE THEREOF | |
| ZA200704921B (en) | Sulfonyl amino cyclic derivatives and use thereof | |
| IL184538A0 (en) | N-hydroxyamide derivatives and use thereof | |
| WO2004045530A3 (en) | Methods for treating, preventing, or reducing cardiac disorders using fadd inhibitors | |
| WO2006085226A3 (en) | Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by insulin-like growth factor binding protein-3 (igfbp-3) | |
| DK1091933T3 (da) | Substituerede beta-diketoner og anvendelse deraf | |
| Veena et al. | FORCED MID-EXPIRATORY FLOW (FEF25-75%) IN SUBJECTS RECOVERED FROM MODERATE AND SEVERE COVID-19 | |
| San-Huang | α-Macroglobulins: a modulator for growth factors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: A61K 33/00, A61K 33/08, A61P 11/00, A61P 17/02, A61P 19/02, A61P 25/16, A61P 25/28, A61P 29/00 Ipc: A61K 33/00 (2011.01), A61K 33/08 (2011.01), A61P 1 |
|
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal: dismissal of application maintained |