BR0302074A - Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesma - Google Patents
Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesmaInfo
- Publication number
- BR0302074A BR0302074A BR0302074-6A BR0302074A BR0302074A BR 0302074 A BR0302074 A BR 0302074A BR 0302074 A BR0302074 A BR 0302074A BR 0302074 A BR0302074 A BR 0302074A
- Authority
- BR
- Brazil
- Prior art keywords
- laurate
- myristate
- porous bodies
- antibiotic
- netylmycin
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 5
- 239000011248 coating agent Substances 0.000 title abstract 4
- 238000000576 coating method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 abstract 7
- 229940070765 laurate Drugs 0.000 abstract 7
- 229940105132 myristate Drugs 0.000 abstract 7
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 abstract 7
- MOTZDAYCYVMXPC-UHFFFAOYSA-N dodecyl hydrogen sulfate Chemical compound CCCCCCCCCCCCOS(O)(=O)=O MOTZDAYCYVMXPC-UHFFFAOYSA-N 0.000 abstract 5
- URWAJWIAIPFPJE-UHFFFAOYSA-N Rickamicin Natural products O1CC(O)(C)C(NC)C(O)C1OC1C(O)C(OC2C(CC=C(CN)O2)N)C(N)CC1N URWAJWIAIPFPJE-UHFFFAOYSA-N 0.000 abstract 3
- 229960000318 kanamycin Drugs 0.000 abstract 3
- 229930027917 kanamycin Natural products 0.000 abstract 3
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 abstract 3
- 229930182823 kanamycin A Natural products 0.000 abstract 3
- URWAJWIAIPFPJE-YFMIWBNJSA-N sisomycin Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC=C(CN)O2)N)[C@@H](N)C[C@H]1N URWAJWIAIPFPJE-YFMIWBNJSA-N 0.000 abstract 3
- 229960000707 tobramycin Drugs 0.000 abstract 3
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 abstract 3
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 abstract 2
- 229930182566 Gentamicin Natural products 0.000 abstract 2
- 108010053950 Teicoplanin Proteins 0.000 abstract 2
- 108010059993 Vancomycin Proteins 0.000 abstract 2
- DDTDNCYHLGRFBM-YZEKDTGTSA-N chembl2367892 Chemical compound CC(=O)N[C@H]1[C@@H](O)[C@H](O)[C@H](CO)O[C@H]1O[C@@H]([C@H]1C(N[C@@H](C2=CC(O)=CC(O[C@@H]3[C@H]([C@H](O)[C@H](O)[C@@H](CO)O3)O)=C2C=2C(O)=CC=C(C=2)[C@@H](NC(=O)[C@@H]2NC(=O)[C@@H]3C=4C=C(O)C=C(C=4)OC=4C(O)=CC=C(C=4)[C@@H](N)C(=O)N[C@H](CC=4C=C(Cl)C(O5)=CC=4)C(=O)N3)C(=O)N1)C(O)=O)=O)C(C=C1Cl)=CC=C1OC1=C(O[C@H]3[C@H]([C@@H](O)[C@H](O)[C@H](CO)O3)NC(C)=O)C5=CC2=C1 DDTDNCYHLGRFBM-YZEKDTGTSA-N 0.000 abstract 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 abstract 2
- 229960002227 clindamycin Drugs 0.000 abstract 2
- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 abstract 2
- 229940043264 dodecyl sulfate Drugs 0.000 abstract 2
- 229960002518 gentamicin Drugs 0.000 abstract 2
- 229960001608 teicoplanin Drugs 0.000 abstract 2
- 229960004821 amikacin Drugs 0.000 abstract 1
- LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229960003405 ciprofloxacin Drugs 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960003165 vancomycin Drugs 0.000 abstract 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 1
- MYPYJXKWCTUITO-LYRMYLQWSA-O vancomycin(1+) Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C([O-])=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)[NH2+]C)[C@H]1C[C@](C)([NH3+])[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-O 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
"REVESTIMENTO ANTIBIóTICO DE CORPOS POROSOS E PROCESSOS PARA PRODUçãO, BEM COMO USO DA MESMA". A invenção refere-se à descrição de um revestimento antibiótico de corpos porosos e uso do mesmo. No sistema de poros de corpos porosos não-metálicos e de corpos porosos metálicos, é inserido um revestimento de pelo menos um sal de antibiótico, pouco solúvel em água ou no meio aquoso, do grupo do laurato de netilmicina, do miristato de netilmicina, do dodecilsulfato de netilmicina, do laurato de sisomicina, do miristato de sisomicina, do dodecilsulfato de sisomicina, do laurato de gentamicina, do miristato de gentamicina, do laurato de clindamicina, do laurato da amicacina, do miristato de amicacina, do dodecilsulfato de amicacina, do laurato de canamicina, do miristato de canamicina, do dodecilsulfato de canamicina, do laurato de tobramicina, do miristato de tobramicina, do dodecilsulfato de tobramicina, do miristato de ciprofloxacina, do dodecilsulfato de vancomicina, do laurato de vancomicina, do miristato de vancomicina, da teicoplanina de vancomicina e da teicoplanina de clindamicina. Os corpos porosos revestidos antibioticamente são usados como implantes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10227935A DE10227935B4 (de) | 2002-06-21 | 2002-06-21 | Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0302074A true BR0302074A (pt) | 2004-04-27 |
Family
ID=29716605
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0302074-6A BR0302074A (pt) | 2002-06-21 | 2003-06-17 | Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesma |
| BRPI0302074-6A BRPI0302074B1 (pt) | 2002-06-21 | 2003-06-17 | Corpos porosos compreendendo um revestimento antibiótico, seus processos para produção, bem como seus usos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0302074-6A BRPI0302074B1 (pt) | 2002-06-21 | 2003-06-17 | Corpos porosos compreendendo um revestimento antibiótico, seus processos para produção, bem como seus usos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7030093B2 (pt) |
| EP (1) | EP1374923B1 (pt) |
| JP (1) | JP4838488B2 (pt) |
| CN (1) | CN1310682C (pt) |
| AT (1) | ATE337802T1 (pt) |
| BR (2) | BR0302074A (pt) |
| CA (1) | CA2431984C (pt) |
| DE (3) | DE10227935B4 (pt) |
| DK (1) | DK1374923T3 (pt) |
| ES (1) | ES2268220T3 (pt) |
| PT (1) | PT1374923E (pt) |
| ZA (1) | ZA200304798B (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10318991A1 (de) * | 2003-04-25 | 2004-11-18 | Heraeus Kulzer Gmbh & Co. Kg | Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung |
| DE102004021739B4 (de) * | 2004-04-30 | 2007-11-22 | Heraeus Kulzer Gmbh | Metallimplantat mit Oberflächenbeschichtung |
| DE102004060666B3 (de) | 2004-12-15 | 2006-03-30 | Heraeus Kulzer Gmbh | Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung |
| ES2387195T3 (es) | 2005-05-27 | 2012-09-17 | Royer Biomedical, Inc. | Matrices de polímero y métodos de fabricación y uso de las mismas |
| DE102006007245A1 (de) | 2006-02-15 | 2007-08-23 | Heraeus Kulzer Gmbh | Implantatmaterial |
| US20070197548A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
| US20070196398A1 (en) * | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone fatty acid salt compositions |
| DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
| CN100418978C (zh) * | 2006-11-01 | 2008-09-17 | 福州大学 | 一种采用膜分离技术制备西索米星的方法 |
| DE102006060934A1 (de) * | 2006-12-20 | 2008-06-26 | Wolter, Dietmar F., Prof. Dr. | Saugdrainage mit einem antibakteriell wirkenden Materialdepot |
| JP5131632B2 (ja) * | 2007-05-10 | 2013-01-30 | 国立大学法人 新潟大学 | 薬物徐放材料及びその製造方法 |
| EP2018864A1 (en) | 2007-07-23 | 2009-01-28 | Biomet Deutschland GmbH | Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition |
| US20090192609A1 (en) * | 2008-01-29 | 2009-07-30 | Zimmer, Inc. | Implant device for use in an implant system |
| US7972615B2 (en) * | 2008-03-27 | 2011-07-05 | Affinergy, Inc. | Peptide compositions for coating metal medical devices with vancomycin |
| DE102010020940B4 (de) | 2010-05-19 | 2014-09-25 | Heraeus Medical Gmbh | Antibiotische Beschichtung |
| DE102010055559B4 (de) | 2010-12-23 | 2015-10-29 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung |
| DE102010055560B4 (de) | 2010-12-23 | 2017-02-23 | Heraeus Medical Gmbh | Beschichtungsvorrichtung |
| DE102010055562B4 (de) | 2010-12-23 | 2015-07-09 | Heraeus Medical Gmbh | Beschichtungsvorrichtung und Beschichtungsverfahren |
| DE102010055561B4 (de) | 2010-12-23 | 2015-12-31 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung |
| DE102011117526B4 (de) | 2011-11-03 | 2015-07-30 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung für medizinische Implantate |
| US9492374B2 (en) | 2015-03-25 | 2016-11-15 | Jose Rafael Salinas Andrade | Composition and method for treatment of ulcers |
| EP3648740A1 (en) | 2017-07-07 | 2020-05-13 | EpicentRx, Inc. | Compositions for parenteral administration of therapeutic agents |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3091572A (en) | 1962-07-16 | 1963-05-28 | Schering Corp | Gentamycin and method of production |
| CA950831A (en) | 1972-04-25 | 1974-07-09 | Leonard D. Kurtz | Biocidal salts |
| FR2272680B1 (pt) | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
| DE2843963A1 (de) | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
| DE2807132C2 (de) | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
| DE3206725A1 (de) | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
| DE3248328A1 (de) * | 1982-12-28 | 1984-06-28 | Bayer Ag, 5090 Leverkusen | Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe |
| DE3377064D1 (en) | 1982-12-28 | 1988-07-21 | Bayer Ag | Stable aminoglycoside-penicillin injection formulation |
| DE3414924A1 (de) * | 1984-04-19 | 1985-10-31 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Beschichtetes verankerungsteil fuer implantate |
| US4749585A (en) * | 1986-04-11 | 1988-06-07 | University Of Medicine And Dentistry Of New Jersey | Antibiotic bonded prosthesis and process for producing same |
| DE3613213A1 (de) * | 1986-04-18 | 1987-10-22 | Merck Patent Gmbh | Tricalciumphosphat fuer implantationsmaterialien |
| DE4304716A1 (de) * | 1993-02-16 | 1994-08-18 | Melzer Wolfgang | Lokal applizierbares Arzneimittel mit verzögerter Freisetzung |
| DE4314871A1 (de) * | 1993-05-05 | 1994-11-10 | Merck Patent Gmbh | Lösungsmittel für ein schwerlösliches Gentamicin-Salz |
| JPH0767895A (ja) * | 1993-06-25 | 1995-03-14 | Sumitomo Electric Ind Ltd | 抗菌性人工血管及び抗菌性手術用縫合糸 |
| DE4404018A1 (de) * | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
| DE19726412A1 (de) * | 1997-06-21 | 1998-12-24 | Merck Patent Gmbh | Implantatmaterial mit einer Träger-Wirkstoff-Kombination |
| EP0985413A1 (de) * | 1998-08-06 | 2000-03-15 | Jörg Michael Dr. Dr. Schierholz | Medizinprodukte mit retardierter pharmakologischer Aktivität und Verfahren zu ihrer Herstellung |
| DE19855421C2 (de) * | 1998-11-02 | 2001-09-20 | Alcove Surfaces Gmbh | Implantat |
| DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
| DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
| IS6390A (is) * | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra |
-
2002
- 2002-06-21 DE DE10227935A patent/DE10227935B4/de not_active Expired - Fee Related
- 2002-06-21 DE DE10262176A patent/DE10262176B4/de not_active Expired - Fee Related
-
2003
- 2003-05-28 AT AT03011967T patent/ATE337802T1/de active
- 2003-05-28 DE DE50304820T patent/DE50304820D1/de not_active Expired - Lifetime
- 2003-05-28 EP EP03011967A patent/EP1374923B1/de not_active Expired - Lifetime
- 2003-05-28 ES ES03011967T patent/ES2268220T3/es not_active Expired - Lifetime
- 2003-05-28 PT PT03011967T patent/PT1374923E/pt unknown
- 2003-05-28 DK DK03011967T patent/DK1374923T3/da active
- 2003-06-12 CA CA002431984A patent/CA2431984C/en not_active Expired - Fee Related
- 2003-06-17 BR BR0302074-6A patent/BR0302074A/pt not_active IP Right Cessation
- 2003-06-17 BR BRPI0302074-6A patent/BRPI0302074B1/pt unknown
- 2003-06-20 US US10/600,548 patent/US7030093B2/en not_active Expired - Lifetime
- 2003-06-20 ZA ZA200304798A patent/ZA200304798B/xx unknown
- 2003-06-20 JP JP2003177000A patent/JP4838488B2/ja not_active Expired - Fee Related
- 2003-06-23 CN CNB031486231A patent/CN1310682C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2431984C (en) | 2009-09-08 |
| EP1374923B1 (de) | 2006-08-30 |
| US20040048786A1 (en) | 2004-03-11 |
| ES2268220T3 (es) | 2007-03-16 |
| DE50304820D1 (de) | 2006-10-12 |
| JP4838488B2 (ja) | 2011-12-14 |
| CN1480226A (zh) | 2004-03-10 |
| DK1374923T3 (da) | 2006-12-27 |
| DE10227935A1 (de) | 2004-01-15 |
| ZA200304798B (en) | 2004-04-29 |
| ATE337802T1 (de) | 2006-09-15 |
| EP1374923A3 (de) | 2004-02-11 |
| DE10227935B4 (de) | 2007-10-04 |
| CA2431984A1 (en) | 2003-12-21 |
| PT1374923E (pt) | 2006-11-30 |
| EP1374923A2 (de) | 2004-01-02 |
| DE10262176B4 (de) | 2007-10-04 |
| AU2003204863A1 (en) | 2004-01-15 |
| JP2004067679A (ja) | 2004-03-04 |
| CN1310682C (zh) | 2007-04-18 |
| US7030093B2 (en) | 2006-04-18 |
| BRPI0302074B1 (pt) | 2018-02-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0302074A (pt) | Revestimento antibiótico de corpos porosos e processos para produção, bem como uso da mesma | |
| ATE341568T1 (de) | Wasserlösliche oder wasserquellbare sulfogruppenhaltige assoziativverdickende copolymere, verfahren zu deren herstellung und ihre verwendung | |
| NO20001973L (no) | Fluidisert polymersuspensjon av hydrofobisk modifiset poly- | |
| DE602004014913D1 (de) | Verbesserte osteoinduktive materialien | |
| NO20042271L (no) | Formuleringer som inneholder en cefalosporinforbindelse og deres anvendelse for behandling av bakterielle infeksjoner i katter og hunder | |
| WO2002009684A3 (en) | ERBB-2 selective small molecule kinase inhibitors | |
| ATE290049T1 (de) | Membran oder matrix zur steuerung der freisetzungsgeschwindigkeit von arzneistoffen | |
| ECSP078011A (es) | DERIVADOS DE PIRIDO[2,3-d]PIRIMIDINA, SU PREPARACION, SU APLICACION EN TERAPEUTICA | |
| CY1108043T1 (el) | Πορωδη σωματα με αντιβιοτικη επικαλυψη, μεθοδος παραγωγης και χρηση | |
| BR9917305A (pt) | Meio de recepção de tinta, conjunto de tinta/meio de recepção de tinta, e, processo de produção de um meio de recepção de tinta | |
| ATE216244T1 (de) | Mometasonfuroat-suspensionen zum zerstäuben | |
| AR027853A1 (es) | Composicion para revestimiento hidrofilica, enlazada convalentemente, para implantes quirurgicos, el implante y el metodo para revestirlo. | |
| BR0301708A (pt) | Preparação farmacêutica com liberação de substância ativas retardada, processo para produção e uso da mesma | |
| BR0207828B1 (pt) | composiÇço de revestimento de nço-isocianato reativa, sistema de revestimento e substrato revestido. | |
| ES2064434T3 (es) | Procedimiento para la conservacion de sistemas acuosos que pueden sufrir degradacion microbiologica. | |
| DE69815295D1 (de) | Kugel oder membranspeicher, z.b. für hydropneumatische fahrzeugaufhängung | |
| FR2871791B1 (fr) | Procede de traitement de milieux aqueux comprenant des sels metalliques de type nitrates ou sulfates | |
| EP1482958A4 (en) | TECHNIQUE FOR TREATING, PREVENTING OR INHIBITING ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC) INFECTIONS WITH BOVINE ERYTHROCYTE PREPARATIONS | |
| ES1040347Y (es) | Rueda perfeccionada para soportes de suspension y/o apoyo de puertas y ventanas correderas. | |
| Soltis | INDUSTRY UPDATE. | |
| TR199900064A3 (tr) | Titanyum alasimi veya paslanmaz çelik yüzeylerin daldirma-kaplama yöntemi kullanilarak kalsiyum hidroksiapatit ile kaplanmasi. | |
| ES1049620Y (es) | Sistema de anclaje para marcos de puertas metalicas. | |
| ITPI980057V0 (it) | Sistema di profili combinati per serramenti, quali in particolare ma non esclusivamente profili alluminio-legno e relativi sistemi di | |
| ITTO990765A0 (it) | Sistema di piani di controllo fluidodinamici per imbarcazioni | |
| ITMO20050029A1 (it) | 'valvola per la frenatura idraulica di rimorchi o simili.' |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25D | Requested change of name of applicant approved |
Owner name: HERAEUS KULZER GMBH (DE) |
|
| B25A | Requested transfer of rights approved |
Owner name: HERAEUS MEDICAL GMBH (DE) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2624 DE 20-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |