BR0308069A - glicose 6-oxidases - Google Patents

glicose 6-oxidases

Info

Publication number
BR0308069A
BR0308069A BRPI0308069-2A BR0308069A BR0308069A BR 0308069 A BR0308069 A BR 0308069A BR 0308069 A BR0308069 A BR 0308069A BR 0308069 A BR0308069 A BR 0308069A
Authority
BR
Brazil
Prior art keywords
glucose
enzymes
galactose
variants
oxidase
Prior art date
Application number
BRPI0308069-2A
Other languages
English (en)
Inventor
Frances H Arnold
Lian-Hong Sun
Loanna P Petrounia
Original Assignee
California Inst Of Techn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn filed Critical California Inst Of Techn
Publication of BR0308069A publication Critical patent/BR0308069A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03004—Glucose oxidase (1.1.3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03009—Galactose oxidase (1.1.3.9)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"GLICOSE 6-OXIDASES". São fornecidas enzimas glicose oxidase incluindo novas variantes de enzimas galactose oxidase. Os polinucleotídeos que abrangem essas novas variantes podem ser expressos em sistemas de expressão de células hospedeiras recombinantes. As novas variantes de enzimas oxidase são capazes de oxidar compostos contra os quais galactose oxidase do tipo selvagem (por exemplo D-galactose: oxigênio 6-oxidorreductase, GAO; EC 1.1.3.9) tem pouca ou nenhuma atividade. Variantes preferidas de galactose oxidase são aquelas que têm capacidade aperfeiçoada para oxidar álcoois secundários e/ou D-glicose relativa à enzimas do tipo selvagem.
BRPI0308069-2A 2002-02-27 2003-02-27 glicose 6-oxidases BR0308069A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35987802P 2002-02-27 2002-02-27
US40041702P 2002-08-01 2002-08-01
PCT/US2003/005655 WO2003072742A2 (en) 2002-02-27 2003-02-27 Novel glucose 6-oxidases

Publications (1)

Publication Number Publication Date
BR0308069A true BR0308069A (pt) 2006-04-11

Family

ID=27767584

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0308069-2A BR0308069A (pt) 2002-02-27 2003-02-27 glicose 6-oxidases

Country Status (6)

Country Link
US (1) US7220563B2 (pt)
EP (1) EP1485404A4 (pt)
AU (1) AU2003230568A1 (pt)
BR (1) BR0308069A (pt)
CA (1) CA2477530A1 (pt)
WO (1) WO2003072742A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2557176A1 (en) * 2011-06-15 2013-02-13 Evonik Degussa GmbH Enzymatic amination
EP2796547B1 (en) * 2013-04-24 2016-09-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Novel glucose oxidase variants
CA3103514A1 (en) 2018-07-09 2020-01-16 Codexis, Inc. Engineered galactose oxidase variant enzymes
EP3599281A1 (en) * 2018-07-26 2020-01-29 Universiteit van Amsterdam Process for the manufacture of nitrile compounds
CN115397977A (zh) * 2020-03-06 2022-11-25 索鲁根公司 用于生产葡萄糖氧化产物的组合物和方法
JP2023517621A (ja) * 2020-03-12 2023-04-26 ソリュゲン インコーポレーテッド ２，５－フランジカルボン酸の製造のための組成物及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5741691A (en) 1996-01-23 1998-04-21 California Institute Of Technology Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media
US6153410A (en) 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
US6498026B2 (en) 2000-02-25 2002-12-24 Hercules Incorporated Variant galactose oxidase, nucleic acid encoding same, and methods of using same
US7115403B1 (en) 2000-05-16 2006-10-03 The California Institute Of Technology Directed evolution of galactose oxidase enzymes

Also Published As

Publication number Publication date
EP1485404A2 (en) 2004-12-15
US7220563B2 (en) 2007-05-22
CA2477530A1 (en) 2003-09-04
AU2003230568A1 (en) 2003-09-09
US20030228673A1 (en) 2003-12-11
EP1485404A4 (en) 2005-03-30
WO2003072742A2 (en) 2003-09-04
WO2003072742A3 (en) 2003-12-24

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