BR1100580A - Composto e complexo - Google Patents
Composto e complexoInfo
- Publication number
- BR1100580A BR1100580A BR1100580-7A BR1100580A BR1100580A BR 1100580 A BR1100580 A BR 1100580A BR 1100580 A BR1100580 A BR 1100580A BR 1100580 A BR1100580 A BR 1100580A
- Authority
- BR
- Brazil
- Prior art keywords
- complex
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1084—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin
- A61K51/109—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin immunoglobulins having two or more different antigen-binding sites or multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21149688A | 1988-06-24 | 1988-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR1100580A true BR1100580A (pt) | 2000-06-06 |
Family
ID=22787153
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR1100574-2A BR1100574A (pt) | 1988-06-24 | 1997-05-13 | Ligantes macrocìclicos e complexos |
| BR1100580-7A BR1100580A (pt) | 1988-06-24 | 1997-05-13 | Composto e complexo |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR1100574-2A BR1100574A (pt) | 1988-06-24 | 1997-05-13 | Ligantes macrocìclicos e complexos |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5652361A (pt) |
| CN (2) | CN1033030C (pt) |
| AU (1) | AU3705889A (pt) |
| BR (2) | BR1100574A (pt) |
| PT (1) | PT90959B (pt) |
| ZA (1) | ZA894792B (pt) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU623901B2 (en) * | 1988-01-26 | 1992-05-28 | Nycomed As | Paramagnetic compounds comprising chelating moiety, linker group macro molecule and paramagnetic metal |
| CA1341373C (en) * | 1988-06-24 | 2002-07-02 | Roberta C. Cheng | Macrocyclic bifunctional chelants, complexes thereof and their antibody conjugates |
| US6139603A (en) * | 1989-02-22 | 2000-10-31 | L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude | Process for recovering oxygen |
| US7597886B2 (en) * | 1994-11-07 | 2009-10-06 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7820798B2 (en) * | 1994-11-07 | 2010-10-26 | Human Genome Sciences, Inc. | Tumor necrosis factor-gamma |
| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| DE19652387A1 (de) * | 1996-12-04 | 1998-06-10 | Schering Ag | Macrocyclische Metallkomplexcarbonsäuren, ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| US6231832B1 (en) | 1998-03-23 | 2001-05-15 | Brookhaven Science Associates | Radiopharmaceutical stannic Sn-117m chelate compositions and methods of use |
| AU3501700A (en) | 1999-02-26 | 2000-09-14 | Human Genome Sciences, Inc. | Human endokine alpha and methods of use |
| EP2213743A1 (en) | 2000-04-12 | 2010-08-04 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| EP2431054A3 (en) | 2000-06-15 | 2013-03-06 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
| PT2281843T (pt) | 2000-06-16 | 2017-01-02 | Human Genome Sciences Inc | Anticorpos que se ligam imunoespecificamente a blys |
| AU8506601A (en) | 2000-08-18 | 2002-03-04 | Dyax Corp | Binding polypeptides for b lymphocyte stimulator protein (blys) |
| US6670456B2 (en) | 2001-02-28 | 2003-12-30 | Dow Global Technologies Inc. | Actinium-225 complexes and conjugates for targeted radiotherapy |
| JP2004536579A (ja) | 2001-04-13 | 2004-12-09 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | 血管内皮増殖因子２ |
| AU2002364586A1 (en) | 2001-12-21 | 2003-07-30 | Delta Biotechnology Limited | Albumin fusion proteins |
| US20080194481A1 (en) | 2001-12-21 | 2008-08-14 | Human Genome Sciences, Inc. | Albumin Fusion Proteins |
| AU2003209340A1 (en) * | 2002-01-18 | 2003-09-02 | Bristol-Myers Squibb Company | Predictor sets for tyrosine kinase pathways |
| AU2003218456A1 (en) * | 2002-04-01 | 2003-10-20 | Human Genome Sciences, Inc. | Antibodies that specifically bind to gmad |
| WO2003086458A1 (en) | 2002-04-12 | 2003-10-23 | Medimmune, Inc. | Recombinant anti-interleukin-9 antibodies |
| AU2003274463B2 (en) | 2002-06-10 | 2009-10-29 | University Of Rochester | Gene differentially expressed in breast and bladder cancer and encoded polypeptides |
| AU2004296184B2 (en) * | 2003-12-04 | 2010-12-16 | Vaccinex, Inc. | Methods of killing tumor cells by targeting internal antigens exposed on apoptotic tumor cells |
| HUE027902T2 (en) | 2004-02-09 | 2016-11-28 | Human Genome Sciences Inc Corp Service Company | Albumin fusion proteins |
| AU2005253962A1 (en) | 2004-06-09 | 2005-12-29 | Kereos, Inc. | Lipophilic derivatives of chelate monoamides |
| US20060210479A1 (en) * | 2004-08-10 | 2006-09-21 | Dow Global Technologies Inc. | Targeting chelants and chelates |
| KR101443050B1 (ko) | 2005-05-06 | 2014-09-22 | 지모제넥틱스, 인코포레이티드 | Ｉｌ-31 단클론성 항체 및 사용법 |
| WO2007142667A2 (en) | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
| NZ615012A (en) | 2006-03-21 | 2015-11-27 | Genentech Inc | Combinatorial therapy involving alpha5beta1 antagonists |
| WO2007126730A1 (en) * | 2006-03-29 | 2007-11-08 | Isotherapeautics Group Llc | Radionuclide therapy for urinary bladder cancer |
| AU2007261247A1 (en) * | 2006-06-22 | 2007-12-27 | Vaccinex, Inc. | Anti-C35 antibodies for treating cancer |
| ES2548714T3 (es) | 2006-09-01 | 2015-10-20 | Zymogenetics, Inc. | Anticuerpos monoclonales IL-31 y procedimientos de uso |
| GB0624587D0 (en) * | 2006-12-08 | 2007-01-17 | Univ Muenchen Tech | Chelating agent |
| MX340566B (es) * | 2007-03-27 | 2016-07-14 | Radiomedix Inc | Composiciones para formacion de imagen objetivo y terapia. |
| ME03057B (me) | 2007-12-07 | 2019-01-20 | Zymogenetics Inc | Molekuli humanizovanih antitela specifični za il-31 |
| CA2710680C (en) | 2007-12-26 | 2018-10-16 | Vaccinex, Inc. | Anti-c35 antibody combination therapies and methods |
| EP2370447B1 (en) * | 2008-12-02 | 2016-07-27 | The University of Melbourne | Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals |
| WO2010093993A2 (en) | 2009-02-12 | 2010-08-19 | Human Genome Sciences, Inc. | Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance |
| NZ594343A (en) | 2009-03-25 | 2013-10-25 | Genentech Inc | Novel anti-alpha5beta1 antibodies and uses thereof |
| WO2011060233A1 (en) | 2009-11-11 | 2011-05-19 | The Trustees Of The University Of Pennsylvania | Anti-tem1 antibodies and uses thereof |
| US20110293629A1 (en) | 2010-05-14 | 2011-12-01 | Bastid Jeremy | Methods of Treating and/or Preventing Cell Proliferation Disorders with IL-17 Antagonists |
| PL2721045T3 (pl) | 2011-06-20 | 2017-11-30 | Radiomedix Inc. | Kompozycie, metody syntezy i zastosowanie węglowodanowych środków ukierunkowanych |
| AU2012278938A1 (en) | 2011-07-07 | 2013-03-07 | Australian Nuclear Science And Technology Organisation | Cryptate compounds |
| US9783610B2 (en) | 2012-04-27 | 2017-10-10 | The Trustees Of The University Of Pennsylvania | Anti-tumor endothelial marker-1 (TEM1) antibody variants and uses thereof |
| EP3613433B1 (en) | 2014-05-30 | 2022-01-05 | Shanghai Henlius Biotech, Inc. | Anti-epidermal growth factor receptor (egfr) antibodies |
| JP6655074B2 (ja) | 2014-06-20 | 2020-02-26 | ジェネンテック， インコーポレイテッド | シャガシンに基づく足場組成物、方法及び使用 |
| WO2016161390A1 (en) | 2015-04-03 | 2016-10-06 | Eureka Therapeutics, Inc. | Constructs targeting afp peptide/mhc complexes and uses thereof |
| WO2016172485A2 (en) | 2015-04-24 | 2016-10-27 | Genentech, Inc. | Multispecific antigen-binding proteins |
| BR112018070948A2 (pt) | 2016-04-13 | 2019-01-29 | Orimabs Ltd. | anticorpos anti-psma e utilização dos mesmos |
| CA3037144A1 (en) | 2016-09-16 | 2018-03-22 | Shanghai Henlius Biotech, Inc. | Anti-pd-1 antibodies |
| EP3568468A4 (en) | 2017-01-12 | 2020-12-30 | Eureka Therapeutics, Inc. | RECOMBINATION PRODUCTS TARGETING PEPTIDE HISTONE H3 / MHC COMPLEXES AND THEIR USES |
| EP3615574A4 (en) | 2017-04-26 | 2021-02-24 | Eureka Therapeutics, Inc. | SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE |
| FR3069245B1 (fr) * | 2017-07-21 | 2019-07-26 | Guerbet | Ligands macrocycliques lipophiles, leurs complexes ainsi que leurs utilisations medicales |
| CN109384737A (zh) * | 2017-08-04 | 2019-02-26 | 天津科伦药物研究有限公司 | 一种四氮杂环钇络合物及其制备方法和应用 |
| EP3765522A4 (en) | 2018-03-14 | 2022-05-18 | Beijing Xuanyi Pharmasciences Co., Ltd. | ANTI-CLAUDIN 18.2 ANTIBODIES |
| US11993661B2 (en) | 2018-06-18 | 2024-05-28 | Eureka Therapeutics, Inc. | Constructs targeting prostate-specific membrane antigen (PSMA) and uses thereof |
| CN112300279A (zh) | 2019-07-26 | 2021-02-02 | 上海复宏汉霖生物技术股份有限公司 | 针对抗cd73抗体和变体的方法和组合物 |
| AU2020409496B2 (en) * | 2019-12-20 | 2026-02-19 | Nrg Pallas B.V. | Chromatographic separation of metals using DOTA-based chelators |
| CN110818795B (zh) | 2020-01-10 | 2020-04-24 | 上海复宏汉霖生物技术股份有限公司 | 抗tigit抗体和使用方法 |
| WO2022116877A1 (en) | 2020-12-02 | 2022-06-09 | Shanghai Henlius Biotech, Inc. | ANTI-GARP/TGFβ ANTIBODIES AND METHODS OF USE |
| KR20240122784A (ko) | 2021-12-17 | 2024-08-13 | 상하이 헨리우스 바이오테크, 인크. | 항-ox40 항체 및 사용 방법 |
| KR20240116755A (ko) | 2021-12-17 | 2024-07-30 | 상하이 헨리우스 바이오테크, 인크. | 항-ox40 항체, 다중 특이적 항체 및 이의 사용 방법 |
| CA3245762A1 (en) | 2022-03-25 | 2023-09-28 | Shanghai Henlius Biologics Co., Ltd. | ANTI-MSLN ANTIBODIES AND METHODS OF USE |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| US4472509A (en) * | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
| US4454106A (en) * | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
| SE8301395L (sv) * | 1983-03-15 | 1984-09-16 | Wallac Oy | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler |
| US4678667A (en) * | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
| EP0232751B1 (en) * | 1986-01-23 | 1991-09-11 | E.R. Squibb & Sons, Inc. | 1-substituted-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| US4885363A (en) * | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| GB8603537D0 (en) * | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
| DE3625417C2 (de) * | 1986-07-28 | 1998-10-08 | Schering Ag | Tetraazacyclododecan-Derivate |
| US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
| GB8719041D0 (en) * | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
-
1989
- 1989-06-23 ZA ZA894792A patent/ZA894792B/xx unknown
- 1989-06-23 PT PT90959A patent/PT90959B/pt not_active IP Right Cessation
- 1989-06-23 CN CN89106401A patent/CN1033030C/zh not_active Expired - Lifetime
- 1989-06-26 AU AU37058/89A patent/AU3705889A/en not_active Abandoned
-
1993
- 1993-03-08 US US08/028,050 patent/US5652361A/en not_active Expired - Lifetime
-
1994
- 1994-12-15 CN CN94119133A patent/CN1050836C/zh not_active Expired - Lifetime
-
1997
- 1997-05-13 BR BR1100574-2A patent/BR1100574A/pt active IP Right Grant
- 1997-05-13 BR BR1100580-7A patent/BR1100580A/pt active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| AU3705889A (en) | 1990-01-04 |
| US5652361A (en) | 1997-07-29 |
| PT90959A (pt) | 1989-12-29 |
| CN1109469A (zh) | 1995-10-04 |
| CN1050836C (zh) | 2000-03-29 |
| PT90959B (pt) | 1995-05-04 |
| ZA894792B (en) | 1991-04-24 |
| CN1044095A (zh) | 1990-07-25 |
| BR1100574A (pt) | 2000-06-06 |
| CN1033030C (zh) | 1996-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR1100580A (pt) | Composto e complexo | |
| ATA901789A (de) | Somatostatinpeptid | |
| BR8806093A (pt) | Trepano | |
| DK348289A (da) | Forbindelser | |
| DE68926597D1 (de) | Mikrorechner | |
| NO176872C (no) | Sentrifugalsikt | |
| FI91488B (fi) | Seula | |
| BR8902098A (pt) | Eletrolisador | |
| DK113291D0 (da) | Homogent enzymimmunassay | |
| BR8906898A (pt) | Jamela | |
| DK137889D0 (da) | Foldeaeske | |
| DK182290D0 (da) | Foldeaeske | |
| DK165575C (da) | Loeftesele | |
| DE68926367D1 (de) | Hydroxymethylcyclobutylpurine | |
| DD277186A3 (de) | Waelzlagerseparator | |
| IT8812575A0 (it) | Parallelografo e tecnigrafo | |
| BR6801964U (pt) | Fecho | |
| SE8800664D0 (sv) | Sikt | |
| ATA14288A (de) | Zugeinheit | |
| BR8806404A (pt) | Multiregua | |
| BR6800913U (pt) | Trailer-sanitarios publico | |
| BR8907290A (pt) | Diisopropilbenzeno-bis-peneoalcanoatos | |
| BR8804416A (pt) | Papa-mosca | |
| BR8803641A (pt) | Tele-loto | |
| BR8803070A (pt) | Rende-lapis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AN | Processing applications according to articles 230 and 231 of law 9279/96: notification of filing an application | ||
| HHFK | Processing applications according to articles 230 and 231 of law 9.279/96: republication | ||
| MT | Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96 | ||
| MT | Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96 | ||
| FGAN | Processing applications according to articles 230 and 231 of law 9.279/96: granting | ||
| NB | Patent issued - articles 230 and 231 of law 9279/96 | ||
| HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law |