BR112012007338A2 - mecanismo acionador restaurável para um dispositivo de aplicação de fármaco - Google Patents

mecanismo acionador restaurável para um dispositivo de aplicação de fármaco

Info

Publication number
BR112012007338A2
BR112012007338A2 BR112012007338A BR112012007338A BR112012007338A2 BR 112012007338 A2 BR112012007338 A2 BR 112012007338A2 BR 112012007338 A BR112012007338 A BR 112012007338A BR 112012007338 A BR112012007338 A BR 112012007338A BR 112012007338 A2 BR112012007338 A2 BR 112012007338A2
Authority
BR
Brazil
Prior art keywords
drive mechanism
drive
gear
piston
delivery device
Prior art date
Application number
BR112012007338A
Other languages
English (en)
Inventor
Catherine Anne Macdonald
Christopher Jones
Garen Kouyoumjian
George Cave
Robert Veasey
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BR112012007338A2 publication Critical patent/BR112012007338A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T74/00—Machine element or mechanism
    • Y10T74/18—Mechanical movements
    • Y10T74/18056—Rotary to or from reciprocating or oscillating
    • Y10T74/18088—Rack and pinion type
    • Y10T74/18128—Clutchable gears

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

patente de invenção: mecanismo acionador restaurável para um dispositivo de aplicação de fármaco. a presente invenção refere-se a um mecanismo acionador restarável para uso em um dispositivo de aplicação de fármaco (10). o dispositivo de aplicação de fármaco (10) tendo uma direção distal (14) e uma direção proximal (12). o mecanismo acionador compreende uma cremalheira acionadora (20) engatada com uma engrenagem acionadora (22), uma cremalheira do êmbolo (30) engatada com umaengrenagem do êmbolo (32) e recursos de acoplamento (50) para acoplar a engrenagem acionadora (22) com a engrenagem do êmbolo (32). em um primeiro estado do mecanismo acionador, a engrenagem acionadora (22) e a engrenagem do êmbolo (32) são acopladas e a cremalheira do êmbolo (30) se move na direção distal (14) quando a cremalheira acionadora (20) é movida na direção distal (14). em um segundo estado do mecanismo acionador, a engrenagem acionadora (22) e a engrenagem do êmbolo (32) são desacopladas e a cremalheira do êmbolo (30) fica móvel na direção proximal (12) para restaurar o mecanismo acionador.
BR112012007338A 2009-09-30 2010-09-29 mecanismo acionador restaurável para um dispositivo de aplicação de fármaco BR112012007338A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09171769 2009-09-30
PCT/EP2010/064430 WO2011039237A1 (en) 2009-09-30 2010-09-29 A resettable drive mechanism for a drug delivery device

Publications (1)

Publication Number Publication Date
BR112012007338A2 true BR112012007338A2 (pt) 2016-10-04

Family

ID=41728140

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012007338A BR112012007338A2 (pt) 2009-09-30 2010-09-29 mecanismo acionador restaurável para um dispositivo de aplicação de fármaco

Country Status (9)

Country Link
US (1) US8968259B2 (pt)
EP (1) EP2482898A1 (pt)
JP (1) JP5756471B2 (pt)
CN (1) CN102612382B (pt)
AU (1) AU2010302987B2 (pt)
BR (1) BR112012007338A2 (pt)
CA (1) CA2773462A1 (pt)
IL (1) IL218836A (pt)
WO (1) WO2011039237A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201015799D0 (en) * 2010-09-21 2010-10-27 Owen Mumford Ltd Autoinjectors
EP2468341A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
JP5897297B2 (ja) * 2011-10-07 2016-03-30 高島産業株式会社 歯科用注射器
JP6030803B2 (ja) * 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド ピニオンシステムを有する用量注射器
GB2511806A (en) * 2013-03-14 2014-09-17 Norton Healthcare Ltd Dispensing mechanism for a medical device
MX2015012901A (es) 2013-03-14 2016-04-04 Norton Healthcare Ltd Mecanismo de dispensacion para un dispositivo medico.
CA2906249C (en) 2013-03-14 2018-01-02 Norton Healthcare Limited Dispensing mechanism for a medical device
CN105209095A (zh) 2013-05-21 2015-12-30 诺和诺德股份有限公司 具有活塞杆联轴器的药物输送装置
JP6382956B2 (ja) 2013-05-21 2018-08-29 ノボ・ノルデイスク・エー／エス 動的な軸方向ストッパ特徴を有する前方装填式の薬剤送達装置
US20160325041A1 (en) * 2014-01-13 2016-11-10 Novo Nordisk A/S Transmission Arrangement for Motorized Drug Delivery Device
PT3099353T (pt) * 2014-01-30 2019-02-19 Medical Injection Devices Inc Dispositivo para administração de medicamentos
WO2016165914A1 (de) 2015-04-13 2016-10-20 Lock Antriebstechnik Gmbh Getriebevorrichtung zur anbringung an einer antriebswelle
EP3395385B1 (en) 2015-12-24 2026-03-25 PHC Holdings Corporation Drug infusion device, cartridge adapter, and drug infusion system
US10894129B2 (en) 2015-12-24 2021-01-19 Phc Holdings Corporation Drug injection device, cartridge adapter, and drug injection system
JP6867741B2 (ja) * 2017-05-22 2021-05-12 Ｐｈｃホールディングス株式会社 薬剤注入システム
JP7344535B2 (ja) * 2019-05-20 2023-09-14 株式会社タスク 定量注射筒用プランジャ及び定量注射筒
CN113615572B (zh) * 2021-08-03 2022-04-12 河南中医药大学 一种转基因棉花抗虫鉴定药剂涂抹器
WO2025132683A1 (en) * 2023-12-21 2025-06-26 Sanofi A medicment delivey system and a drive sub-assembly

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1014706A (en) * 1905-07-06 1912-01-16 Lewis T Houghton Mechanism for reciprocating planer-beds or similar purposes.
US3981204A (en) * 1975-01-06 1976-09-21 Starbard Raymond Edward Shock absorber drive unit
US4465478A (en) * 1982-10-14 1984-08-14 Collagen Corporation Syringe force amplification device
FR2683140B1 (fr) 1991-11-06 1994-02-11 Derien Jean Charles Pistolet doseur.
US6074372A (en) * 1997-06-09 2000-06-13 Novo Nordisk A/S Dose setting mechanism and an injection syringe having such a dose setting mechanism
EP2275158B1 (en) 2001-05-16 2013-01-23 Eli Lilly and Company Medication injector apparatus
US7678084B2 (en) 2002-03-18 2010-03-16 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
AU2003239785A1 (en) * 2002-07-10 2004-02-02 Novo Nordisk A/S An injection device with a dose setting limiter
DE10240165A1 (de) * 2002-08-30 2004-03-18 Disetronic Licensing Ag Vorrichtung zum dosierten Ausstoßen eines flüssigen Wirkstoffes und Infusionspumpe
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
JP2005261685A (ja) 2004-03-18 2005-09-29 Matsushita Electric Ind Co Ltd 薬液投与装置
US20090254060A1 (en) * 2008-04-02 2009-10-08 Hetherington Hugh E Motor assembly for injection control device

Also Published As

Publication number Publication date
AU2010302987A1 (en) 2012-04-19
JP2013506467A (ja) 2013-02-28
US20120279329A1 (en) 2012-11-08
US8968259B2 (en) 2015-03-03
AU2010302987B2 (en) 2015-01-29
CN102612382A (zh) 2012-07-25
EP2482898A1 (en) 2012-08-08
CN102612382B (zh) 2014-05-07
IL218836A0 (en) 2012-06-28
IL218836A (en) 2014-11-30
CA2773462A1 (en) 2011-04-07
WO2011039237A1 (en) 2011-04-07
JP5756471B2 (ja) 2015-07-29

Similar Documents

Publication Publication Date Title
BR112012007608A2 (pt) mecanismo de acionamento para um dispositivo de distribuição de fármaco e uso de um elemento elástico para um mecanismo de acionamento
CO6210736A2 (es) Mejoras en y relacionadas con mecanismos accionadores adecuados para usarse en dispositivos de descarga de farmacos
BR112012007310A2 (pt) mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento
BR112012007067A2 (pt) montagem de acionamento, haste de pistão, dispositivo de distribuição de fármaco e uso de uma mola
BR112014012507A2 (pt) autoinjetor
CL2008003153A1 (es) Compuestos espiro condensados, agonistas de gpr40: composicion farmaceutica que comprende a uno de los compuestos; y el uso de los compuestos en la preparacion de medicamentos para el tratamiento de la diabetes, hiperglicemia, alteracion de tolerancia a la glucosa en ayuna, entre otras.
ES2627734T3 (es) Dispositivo de administración de medicamento que comprende un mecanismo de bloqueo
EP2611482A4 (en) APPARATUS FOR MEDICAMENT ADMINISTRATION
BR112014004648A2 (pt) dispositivo cirúrgico de corte e fixação com disposição descendente do segundo acionador
BR112013020907A2 (pt) autoinjetor
BR112012007296A2 (pt) mecanismo de acionamento para dispositivo de distribuição de fármaco
BR112012007120A2 (pt) dispositivo de liberação de fármaco e elemento de acionamento para um dispositivo de liberação de fármaco
ATE516834T1 (de) Verabreichungsvorrichtung mit funktionalem antriebsglied
BR112013020670A2 (pt) injetor automático
BR112014012480A2 (pt) seringa de segurança
AR083787A1 (es) Composicion farmaceutica que comprende un inhibidor del transportador 2 de sodio-glucosa (sglt2) y una insulina, procedimientos de tratamiento y usos de la misma
AR073447A1 (es) Conjunto de accionamiento adecuado para uso en un dispositivo de suministro de medicamento, y dispositivo de suministro de medicamento
BRPI0903317B8 (pt) unidade de carga descartável para uso com um aparelho de grampeamento cirúrgico
WO2012117379A3 (fr) Inserteur de canule
BR112013019932A2 (pt) dispositivo de liberação de medicamento
BR112013025628A2 (pt) dispositivo de liberação de medicamento compreendendo um mecanismo de travamento com uma alavanca
EP3066991A3 (en) Apparatus for endoscopic procedures
MY166814A (en) Auto-injector
UA99366C2 (ru) Устройство подачи лекарственного средства, применение устройства подачи лекарственного средства и способ производства или сборки устройства подачи лекарственного средства
WO2010033770A3 (en) Medical injector with ratcheting plunger

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]