BR112018010902A2 - método de eletroquimioluminescência, aparelho para executar um método de eletroquimioluminescência e produto de programa de computador - Google Patents

método de eletroquimioluminescência, aparelho para executar um método de eletroquimioluminescência e produto de programa de computador

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Publication number
BR112018010902A2
BR112018010902A2 BR112018010902A BR112018010902A BR112018010902A2 BR 112018010902 A2 BR112018010902 A2 BR 112018010902A2 BR 112018010902 A BR112018010902 A BR 112018010902A BR 112018010902 A BR112018010902 A BR 112018010902A BR 112018010902 A2 BR112018010902 A2 BR 112018010902A2
Authority
BR
Brazil
Prior art keywords
analyte
perform
electrochemiluminescence method
electrochemiluminescence
measurement cycle
Prior art date
Application number
BR112018010902A
Other languages
English (en)
Inventor
Andreas Bauer-Espindola Klaus
Quint Stefan
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112018010902A2 publication Critical patent/BR112018010902A2/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00623—Quality control of instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N2035/00891—Displaying information to the operator

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Quality & Reliability (AREA)
  • Electrochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

trata-se de um método de eletroquimioluminescência para detectar um analito em uma amostra líquida com o uso de uma célula medidora (108), sendo que a célula medidora (108) compreende um eletrodo de trabalho (120) para detectar o analito com o uso de um ciclo de medição de eletroquimioluminescência, em que o método compreende a. realizar o ciclo de medição em um processo de calibragem com o uso de uma amostra líquida desprovida do analito e executar uma primeira espectroscopia de impedância eletroquímica, eis, em um ponto determinado do ciclo de medição, sendo que a primeira eis é executada com o uso do eletrodo de trabalho (120), b. realizar o ciclo de medição em um processo de análise com o uso da amostra líquida que contém o analito e executar uma segunda eis em um ponto determinado do ciclo de medição, sendo que a segunda eis é executada com o uso do eletrodo de trabalho (120), c. comparar o resultado da primeira eis e da segunda eis, fornecer uma indicação de um estado de medição que indica se a comparação resulta em um desvio entre a primeira eis e a segunda eis que excede um limite predefinido.
BR112018010902A 2016-01-29 2017-01-27 método de eletroquimioluminescência, aparelho para executar um método de eletroquimioluminescência e produto de programa de computador BR112018010902A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16153257 2016-01-29
EP16158014 2016-03-01
PCT/EP2017/051868 WO2017129803A1 (en) 2016-01-29 2017-01-27 Electrochemiluminescence method and apparatus for detecting an analyte in a liquid sample

Publications (1)

Publication Number Publication Date
BR112018010902A2 true BR112018010902A2 (pt) 2018-11-21

Family

ID=57914974

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018010902A BR112018010902A2 (pt) 2016-01-29 2017-01-27 método de eletroquimioluminescência, aparelho para executar um método de eletroquimioluminescência e produto de programa de computador

Country Status (8)

Country Link
US (1) US11796477B2 (pt)
EP (1) EP3408401B1 (pt)
JP (1) JP7041623B2 (pt)
KR (1) KR20180105127A (pt)
CN (1) CN108431231B (pt)
BR (1) BR112018010902A2 (pt)
ES (1) ES2770223T3 (pt)
WO (1) WO2017129803A1 (pt)

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TWI703322B (zh) * 2018-10-04 2020-09-01 台灣奈米碳素股份有限公司 生化檢驗方法及裝置
CN113287022B (zh) * 2018-12-27 2023-12-12 株式会社日立高新技术 自动分析装置、自动分析系统及样品的自动分析方法
CN114375391B (zh) * 2019-07-31 2024-12-03 株式会社日立高新技术 生物分子分析方法和生物分子分析装置
EP3786628A1 (en) * 2019-08-29 2021-03-03 Metrohm Ag Method and device for determining at least one analyte species in an analyte solution
CN111198181A (zh) * 2020-01-10 2020-05-26 苏州易莱生物技术有限公司 用于电化学发光检测的方法和装置
US11771368B2 (en) 2020-03-09 2023-10-03 Arizona Board Of Regents On Behalf Of Arizona State University Rapid assessment of microcirculation in patients to realize closed-loop systems
US11953532B2 (en) * 2020-03-09 2024-04-09 Arizona Board Of Regents On Behalf Of Arizona State University Systems and methods to determine electrochemical impedance spectrogram rapidly in real time
KR102448945B1 (ko) * 2021-01-08 2022-09-30 주식회사 위즈맥 Eis 측정 및 알고리즘 방식을 통한 전기화학 전극센서 트랜스듀서의 자동 교정 방법, 수명 진단 방법, 및 양불 진단 방법
CN114371161B (zh) * 2021-11-15 2023-09-22 吉林大学 一种基于具有偏振分辨特性的表面增敏电化学发光分析方法及应用
JP7455249B1 (ja) 2023-02-27 2024-03-25 住友化学株式会社 電気化学的測定方法、電気化学的測定装置、及びプログラム
CN117239884B (zh) * 2023-11-14 2024-02-02 西南交通大学 具有超宽频eis测量功能的电池功率接口变换器控制方法

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Also Published As

Publication number Publication date
US11796477B2 (en) 2023-10-24
EP3408401A1 (en) 2018-12-05
JP7041623B2 (ja) 2022-03-24
CN108431231A (zh) 2018-08-21
ES2770223T3 (es) 2020-07-01
CN108431231B (zh) 2021-09-10
WO2017129803A1 (en) 2017-08-03
KR20180105127A (ko) 2018-09-27
JP2019512665A (ja) 2019-05-16
EP3408401B1 (en) 2019-11-20
US20180348140A1 (en) 2018-12-06

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements