BR112018016341A2 - solução de bloqueio do cateter e terapia de bloqueio do cateter - Google Patents

solução de bloqueio do cateter e terapia de bloqueio do cateter

Info

Publication number
BR112018016341A2
BR112018016341A2 BR112018016341-4A BR112018016341A BR112018016341A2 BR 112018016341 A2 BR112018016341 A2 BR 112018016341A2 BR 112018016341 A BR112018016341 A BR 112018016341A BR 112018016341 A2 BR112018016341 A2 BR 112018016341A2
Authority
BR
Brazil
Prior art keywords
catheter block
catheter
ethyl alcohol
solution
volume
Prior art date
Application number
BR112018016341-4A
Other languages
English (en)
Other versions
BR112018016341B1 (pt
Inventor
Babu Premkumar
R. BROZANSKI Benjamin
PAGANO Lisa
S. BENNETT Jeffrey
Original Assignee
Medical Components, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Components, Inc. filed Critical Medical Components, Inc.
Publication of BR112018016341A2 publication Critical patent/BR112018016341A2/pt
Publication of BR112018016341B1 publication Critical patent/BR112018016341B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M2025/0019—Cleaning catheters or the like, e.g. for reuse of the device, for avoiding replacement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0017—Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

várias modalidades se referem a soluções de bloqueio de cateter e terapias de bloqueio de cateter com uso de citrato trissódico e álcool etílico e, em particular, 4,0 a 15,0% em peso/volume de citrato trissódico como componente anticoagulante e/ou componente antibacteriano e 15,0 a 25,0 % volume/volume de álcool etílico como um componente antibacteriano. a utilização da solução de bloqueio de cateter e a terapia de bloqueio de cateter pode reduzir a falha do tratamento durante procedimentos médicos que podem empregar cateteres para fornecer tratamento pelo menos reduzindo significativamente os riscos associados a infecções da corrente sanguínea, mau funcionamento do sistema de cateter, formação de êmbolos, desconforto do paciente e doença do paciente. estes benefícios podem ser parcialmente devidos aos efeitos antibacterianos sinérgicos do citrato trissódico e do álcool etílico em solução, gerando uma solução eficaz de bloqueio do cateter com concentrações mínimas de álcool etílico.
BR112018016341-4A 2016-02-12 2017-02-06 Solução de bloqueio de cateter BR112018016341B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662294478P 2016-02-12 2016-02-12
US62/294,478 2016-02-12
PCT/US2017/016682 WO2017139224A1 (en) 2016-02-12 2017-02-06 Catheter locking solution and catheter locking therapy

Publications (2)

Publication Number Publication Date
BR112018016341A2 true BR112018016341A2 (pt) 2018-12-18
BR112018016341B1 BR112018016341B1 (pt) 2022-02-08

Family

ID=58191579

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018016341-4A BR112018016341B1 (pt) 2016-02-12 2017-02-06 Solução de bloqueio de cateter

Country Status (13)

Country Link
US (2) US10940240B2 (pt)
EP (1) EP3413942B1 (pt)
JP (1) JP6909226B2 (pt)
CN (1) CN108697826A (pt)
AU (2) AU2017217011B2 (pt)
BR (1) BR112018016341B1 (pt)
CA (1) CA3013914C (pt)
ES (1) ES2936820T3 (pt)
IL (1) IL260771B2 (pt)
MX (2) MX391227B (pt)
RU (1) RU2734929C2 (pt)
TW (1) TWI738714B (pt)
WO (1) WO2017139224A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5548121B2 (ja) 2007-05-14 2014-07-16 リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク バイオフィルム中の細菌細胞における生理学的分散応答の誘導
US10493232B2 (en) 2015-07-20 2019-12-03 Strataca Systems Limited Ureteral catheters, bladder catheters, systems, kits and methods for inducing negative pressure to increase renal function
US11040172B2 (en) 2015-07-20 2021-06-22 Strataca Systems Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
US10918827B2 (en) 2015-07-20 2021-02-16 Strataca Systems Limited Catheter device and method for inducing negative pressure in a patient's bladder
US10926062B2 (en) 2015-07-20 2021-02-23 Strataca Systems Limited Ureteral and bladder catheters and methods of inducing negative pressure to increase renal perfusion
US11541205B2 (en) * 2015-07-20 2023-01-03 Roivios Limited Coated urinary catheter or ureteral stent and method
US11229771B2 (en) 2015-07-20 2022-01-25 Roivios Limited Percutaneous ureteral catheter
US12064567B2 (en) 2015-07-20 2024-08-20 Roivios Limited Percutaneous urinary catheter
US10512713B2 (en) 2015-07-20 2019-12-24 Strataca Systems Limited Method of removing excess fluid from a patient with hemodilution
CN112691278B (zh) 2015-07-20 2024-03-22 罗维奥斯有限公司 输尿管和膀胱导管及引入负压以增加肾灌注的方法
JP7132633B2 (ja) 2016-12-27 2022-09-07 ヴァソニクス・インコーポレイテッド カテーテルハウジング
MX2020002064A (es) 2017-08-25 2020-10-16 Roivios Ltd Bomba permanente para facilitar la extracción de orina del tracto urinario.
JP7138702B2 (ja) * 2017-09-22 2022-09-16 ベクトン・ディキンソン・アンド・カンパニー カテーテルロック溶液としての使用のための４％クエン酸三ナトリウム溶液
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US12472301B2 (en) 2021-08-13 2025-11-18 3Ive Labs, Llc Negative pressure therapy system and methods

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1097336A1 (ru) * 1982-04-21 1984-06-15 Институт сердечно-сосудистой хирургии им.А.Н.Бакулева Способ получени тромборезистентных полимерных изделий,контактирующих с кровью
ATE342103T1 (de) 1998-08-25 2006-11-15 Ash Access Technology Inc Verwendung von citrat in einer kathetersperrlösung
US6679870B1 (en) * 1999-07-23 2004-01-20 Vasca, Inc. Methods and kits for locking and disinfecting implanted catheters
US6685694B2 (en) * 1999-07-23 2004-02-03 Vasca, Inc. Methods and kits for locking and disinfecting implanted catheters
EP1284780B1 (en) 2000-05-10 2008-05-07 Ash Access Technology, Inc. A catheter lock solution including a photo-oxidant
JP5143982B2 (ja) * 2001-05-08 2013-02-13 エヌディー パートナーズ，リミティド ライアビリティー カンパニー 殺生物剤ロック
US20050215978A1 (en) * 2001-05-25 2005-09-29 Ash Stephen R Method of enhancing catheter patency using a citrate salt catheter lock solution
US8541472B2 (en) * 2001-12-05 2013-09-24 Aseptica, Inc. Antiseptic compositions, methods and systems
US20030144362A1 (en) 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US20050136118A1 (en) 2003-12-19 2005-06-23 Wu Su-Syin S. Distribution and preparation of germicidal compositions
US7749529B2 (en) 2005-02-08 2010-07-06 Ash Access Technology, Inc. Catheter lock solution comprising citrate and a paraben
KR20160023926A (ko) * 2006-02-28 2016-03-03 벡톤 디킨슨 앤드 컴퍼니 카테테르 잠금을 위한 항미생물성 조성물 및 방법
US20080279907A1 (en) * 2007-05-10 2008-11-13 Ash Access Technology, Inc. Antimicrobial medical devices and methods for making and using same
CN101112627B (zh) * 2007-05-29 2011-12-21 中国人民解放军第二军医大学 封管用枸橼酸钠注射液及其制备方法
DE102007036685A1 (de) * 2007-08-03 2009-02-05 Innora Gmbh Verbesserte arzneimittelbeschichtete Medizinprodukte deren Herstellung und Verwendung
US9248093B2 (en) * 2009-06-11 2016-02-02 Becton, Dickinson And Company Catheter locking solution having antimicrobial and anticoagulation properties
EP2550030B1 (en) * 2010-03-25 2018-04-25 Lutonix, Inc. Drug releasing coatings for medical devices
US8951577B2 (en) 2010-08-03 2015-02-10 Teleflex Medical Incorporated Antimicrobial hydrochloric acid catheter lock solution and method of use
US9565857B2 (en) 2010-09-10 2017-02-14 Board Of Regents, The University Of Texas System Antimicrobial solutions
FR2985667B1 (fr) 2012-01-12 2014-08-22 Univ Dauvergne Clermont I Composition verrou aqueuse comprenant de l'ethanol et un anticoagulant polysaccharidique
US9457002B2 (en) * 2012-08-08 2016-10-04 Board Of Regents, The University Of Texas System Antimicrobial compositions comprising glyceryl nitrates
US10300176B2 (en) * 2013-11-25 2019-05-28 Medline Industries, Inc. Catheter lock solution formulations

Also Published As

Publication number Publication date
RU2020134168A (ru) 2020-11-24
US10940240B2 (en) 2021-03-09
JP6909226B2 (ja) 2021-07-28
CA3013914C (en) 2024-02-06
MX2018009764A (es) 2018-09-10
MX391227B (es) 2025-03-21
IL260771B2 (en) 2023-09-01
RU2018132353A3 (pt) 2020-05-20
RU2734929C2 (ru) 2020-10-26
US20210170075A1 (en) 2021-06-10
CA3013914A1 (en) 2017-08-17
RU2020134168A3 (pt) 2021-09-14
IL260771B1 (en) 2023-05-01
TWI738714B (zh) 2021-09-11
AU2017217011B2 (en) 2021-06-03
US20170232153A1 (en) 2017-08-17
IL260771A (pt) 2018-09-20
CN108697826A (zh) 2018-10-23
TW201731553A (zh) 2017-09-16
EP3413942B1 (en) 2023-01-11
BR112018016341B1 (pt) 2022-02-08
JP2019506223A (ja) 2019-03-07
WO2017139224A1 (en) 2017-08-17
MX2022004012A (es) 2022-05-02
AU2021203473A1 (en) 2021-06-24
AU2017217011A1 (en) 2018-08-09
ES2936820T3 (es) 2023-03-22
EP3413942A1 (en) 2018-12-19
RU2018132353A (ru) 2020-03-12

Similar Documents

Publication Publication Date Title
BR112018016341A2 (pt) solução de bloqueio do cateter e terapia de bloqueio do cateter
BR112018075682A2 (pt) inibidores de papd5 e papd7 para tratamento de infecção pela hepatite b
BR112017024934A2 (pt) composições farmacêuticas tópicas
BR112016000177A2 (pt) usos de um antagonista do vegf no tratamento de doenças neovasculares coriorretinianas e de permeabilidade em pacientes pediátricos, seringa pré-cheia, kit e formulação de liberação lenta
BR112015027282A8 (pt) formulação líquida e kit compreendendo fenfluramina, e usos da mesma no tratamento de síndrome de dravet
BR112016002171A2 (pt) método, composição estéril e injetável e método para preparar uma composição estéril e injetável
BR112018075579A2 (pt) sistemas e métodos para corrigir e prevenir a oclusão em um cateter
BR112013018920A2 (pt) composições de nanopartículas, formulações destas e seus usos
BR112016013961A2 (pt) angiotensina ii sozinha ou em combinação para o tratamento da hipotensão
MX394496B (es) Administracion de metabolitos de berberina
CL2018000002A1 (es) Agente terapéutico y método para tratar el síndrome de hunter.
BR112017006272A2 (pt) composição farmacêutica para tratar colite ulcerativa.
BR112012027092A2 (pt) métodos e composiões para reduzir ou impedir a calcificação vascular durante a terapia de diálise peritoneal
BR112017000058A2 (pt) dispositivos e métodos para esclero espumas vasculares injetáveis utilizando uma matriz carreadora e seus usos
MX2022012354A (es) Metodos de administracion de una preparacion inyectable de aripiprazol.
MX2021010834A (es) Compuesto y metodo para la prevencion de transmision del virus de influenza.
BR112015023806A2 (pt) Novos regimes de dosagem de celgosivir para o tratamento de dengue
BR112015022084A2 (pt) composições para uso em tratamento de distúrbios oculares com o uso de dipiridamol
BR112019018185A2 (pt) composição para tratar uma doença de articulação humana, e, kit.
BR112018072177A2 (pt) composição farmacêutica, recipiente, e, métodos para tratar e prevenir congestão nasal, infecções virais do trato respiratório e/ou inflamação da garganta
BR112018071860A2 (pt) derivados de prostaglandina
BR112022019486A2 (pt) Agente terapêutico para infecção por coronavírus
BR112014005653A2 (pt) uso de 4-amino-5-fluoro-3[6-(4-metilpiperazin-1-il)-1h-benzimidazol-2-1l]1h-quinolin-ona no tratamento de câncer de em pacientes com insuficiência hepática moderada
MX375350B (es) Medicamento para el tratamiento de infecciones de pie diabetico
BR112015009291A2 (pt) métodos para o controle da pressão arterial e redução da dispnéia na insuficiência cardíaca

Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/02/2017, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 9A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2865 DE 02-12-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.