BR112019018108A2 - Produção enzimática de hexoses - Google Patents

Produção enzimática de hexoses

Info

Publication number
BR112019018108A2
BR112019018108A2 BR112019018108A BR112019018108A BR112019018108A2 BR 112019018108 A2 BR112019018108 A2 BR 112019018108A2 BR 112019018108 A BR112019018108 A BR 112019018108A BR 112019018108 A BR112019018108 A BR 112019018108A BR 112019018108 A2 BR112019018108 A2 BR 112019018108A2
Authority
BR
Brazil
Prior art keywords
hexoses
enzymatic production
enzymatic
production
methods
Prior art date
Application number
BR112019018108A
Other languages
English (en)
Inventor
Joseph Wichelecki Daniel
O Rogers Edwin
Original Assignee
Bonumose Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonumose Llc filed Critical Bonumose Llc
Publication of BR112019018108A2 publication Critical patent/BR112019018108A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01001—Phosphorylase (2.4.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03011—Fructose-bisphosphatase (3.1.3.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01008—Mannose-6-phosphate isomerase (5.3.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01009—Glucose-6-phosphate isomerase (5.3.1.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/02—Phosphotransferases (phosphomutases) (5.4.2)
    • C12Y504/02002—Phosphoglucomutase (5.4.2.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

produção enzimática de hexoses. a invenção refere-se a métodos de produção de hexoses a partir de sacarídeos através de processos enzimáticos. os métodos utilizam frutose 6-fosfato e pelo menos uma etapa enzimática para convertê-la em uma hexose.
BR112019018108A 2017-03-13 2018-03-13 Produção enzimática de hexoses BR112019018108A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762470605P 2017-03-13 2017-03-13
US201762470620P 2017-03-13 2017-03-13
US201762480798P 2017-04-03 2017-04-03
US201762482148P 2017-04-05 2017-04-05
PCT/US2018/022185 WO2018169957A1 (en) 2017-03-13 2018-03-13 Enzymatic production of hexoses

Publications (1)

Publication Number Publication Date
BR112019018108A2 true BR112019018108A2 (pt) 2022-06-14

Family

ID=63523885

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019018108A BR112019018108A2 (pt) 2017-03-13 2018-03-13 Produção enzimática de hexoses

Country Status (13)

Country Link
US (5) US11345909B2 (pt)
EP (1) EP3596212A4 (pt)
JP (3) JP7140401B2 (pt)
KR (2) KR102694973B1 (pt)
CN (1) CN110914422A (pt)
BR (1) BR112019018108A2 (pt)
CA (2) CA3281321A1 (pt)
IL (2) IL317454A (pt)
MA (1) MA49847A (pt)
MX (2) MX2019009863A (pt)
RU (1) RU2766710C2 (pt)
SG (1) SG11201908470UA (pt)
WO (1) WO2018169957A1 (pt)

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WO2018129275A1 (en) 2017-01-06 2018-07-12 Greenlight Biosciences, Inc. Cell-free production of sugars
CN110079488A (zh) * 2018-01-25 2019-08-02 中国科学院天津工业生物技术研究所 一种生产阿洛酮糖的工程菌株，其构建方法及应用
CA3118101A1 (en) * 2018-10-29 2020-05-07 Bonumose, Inc. Enzymatic production of hexoses
KR102233375B1 (ko) * 2018-12-11 2021-03-31 씨제이제일제당 주식회사 신규 싸이코스-6-인산의 탈인산화 효소, 이를 포함하는 싸이코스 생산용 조성물, 및 이를 이용한 싸이코스 제조방법
SG11202108304PA (en) * 2019-02-12 2021-08-30 Bonumose Inc Enzymatic production of mannose
CN109750011B (zh) * 2019-02-20 2022-05-10 中国科学院天津工业生物技术研究所 一种甘露糖6-磷酸磷酸酶及甘露糖生物制备方法
BR112021024211A2 (pt) * 2019-05-31 2022-03-08 Bonumose Inc Produção enzimática de frutose
WO2021011881A1 (en) * 2019-07-17 2021-01-21 Bonumose Llc Immobilized enzyme compositions for the production of hexoses
US20240200109A9 (en) * 2019-07-17 2024-06-20 Bonumose, Inc. Immobilized enzyme compositions for the production of hexoses
US20220372535A1 (en) * 2019-10-28 2022-11-24 Samyang Corporation Fructose-6-phosphate 3-epimerase and use thereof
EP3839054A1 (en) * 2019-12-20 2021-06-23 Cascat GmbH Production of fructose from oligo- and/or polysaccharides
US20230183768A1 (en) * 2020-05-18 2023-06-15 Bonumose, Inc. Enzymatic production of allulose
CN112680482B (zh) * 2021-01-12 2022-12-20 中国科学院天津工业生物技术研究所 一种甘露醇的生物制备方法
EP4288531A4 (en) * 2021-02-02 2025-06-25 Bonumose, Inc. ENZYMATIC ENRICHEMENT OF FOOD INGREDIENTS FOR SUGAR REDUCTION
CN113913481B (zh) * 2021-12-13 2022-03-25 中国科学院天津工业生物技术研究所 甘露糖的生物制备方法
CN114645070B (zh) * 2022-02-28 2022-12-20 北京焉支山科技有限公司 一种己糖-6-磷酸组合物的制备方法及其在化妆品中的应用
EP4488375A1 (de) 2023-07-07 2025-01-08 Annikki GmbH Verfahren zur herstellung einer wässrigen lösung enthaltend allose
WO2025049645A1 (en) * 2023-08-31 2025-03-06 Nutrishus Brands Inc. Disaccharide with metabolic benefits and monosaccharide mixtures

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CN110079488A (zh) 2018-01-25 2019-08-02 中国科学院天津工业生物技术研究所 一种生产阿洛酮糖的工程菌株，其构建方法及应用
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Also Published As

Publication number Publication date
MX2019009863A (es) 2020-02-13
IL269219A (en) 2019-11-28
US20220290117A1 (en) 2022-09-15
CA3056604A1 (en) 2018-09-20
CA3056604C (en) 2025-11-25
RU2019132203A (ru) 2021-04-14
MX2023007865A (es) 2023-07-07
US20200131547A1 (en) 2020-04-30
IL269219B2 (en) 2025-05-01
EP3596212A4 (en) 2021-06-02
US11993796B2 (en) 2024-05-28
JP2020509765A (ja) 2020-04-02
IL269219B1 (en) 2025-01-01
US11345909B2 (en) 2022-05-31
RU2766710C2 (ru) 2022-03-15
KR20240125077A (ko) 2024-08-19
US20240352440A1 (en) 2024-10-24
MA49847A (fr) 2021-06-02
JP7140401B2 (ja) 2022-09-21
KR20190128681A (ko) 2019-11-18
RU2019132203A3 (pt) 2021-07-01
CN110914422A (zh) 2020-03-24
CA3281321A1 (en) 2026-03-02
IL317454A (en) 2025-02-01
JP2025061690A (ja) 2025-04-11
SG11201908470UA (en) 2019-10-30
EP3596212A1 (en) 2020-01-22
US20200131499A1 (en) 2020-04-30
US10745683B2 (en) 2020-08-18
US20200010824A1 (en) 2020-01-09
US12584121B2 (en) 2026-03-24
US11236320B2 (en) 2022-02-01
JP2022173237A (ja) 2022-11-18
KR102694973B1 (ko) 2024-08-16
WO2018169957A1 (en) 2018-09-20

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