BR9206237A - Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-HT1. - Google Patents

Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-HT1.

Info

Publication number: BR9206237A
Authority: BR; Brazil
Prior art keywords: tetrahydrocarbazole derivatives; agonist receptors; agonist; receptors; tetrahydrocarbazole
Prior art date: 1991-06-26

Application number

BR9206237A

Other languages

English (en)

Inventor

Francis David King

Laramie Mary Gaster

Alberto Julio Kaumann

Rodney Christopher Young

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-26

Filing date

1992-06-17

Publication date

1995-04-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10697363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9206237(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-06-17 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1995-04-11 Publication of BR9206237A publication Critical patent/BR9206237A/pt

Links

XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical class N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 title 1
239000003521 serotonin 5-HT1 receptor agonist Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BR9206237A 1991-06-26 1992-06-17 Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-HT1. BR9206237A (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB919113802A GB9113802D0 (en)	1991-06-26	1991-06-26	Medicaments
US08/167,846 US5464864A (en)	1991-06-26	1992-06-17	Use of tetrahydrocarbazone derivatives as 5HT1 receptor agonists
PCT/GB1992/001082 WO1993000086A1 (en)	1991-06-26	1992-06-17	Use of tetrahydrocarbazone derivatives as 5ht1 receptor agonists

Publications (1)

Publication Number	Publication Date
BR9206237A true BR9206237A (pt)	1995-04-11

Family

ID=10697363

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BR9206237A BR9206237A (pt)	1991-06-26	1992-06-17	Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-HT1.
BR1100460-6A BR1100460A (pt)	1991-06-26	1997-05-06	Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-ht1

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BR1100460-6A BR1100460A (pt)	1991-06-26	1997-05-06	Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-ht1

Country Status (34)

Country	Link
US (2)	US5464864A (pt)
EP (1)	EP0591280B1 (pt)
JP (1)	JP3261502B2 (pt)
KR (1)	KR100251571B1 (pt)
CN (1)	CN1034072C (pt)
AP (1)	AP344A (pt)
AT (1)	ATE170746T1 (pt)
BR (2)	BR9206237A (pt)
CA (1)	CA2113726C (pt)
CZ (3)	CZ150696A3 (pt)
DE (2)	DE69226953T2 (pt)
DK (1)	DK0591280T3 (pt)
FI (1)	FI103967B (pt)
GB (1)	GB9113802D0 (pt)
HU (1)	HU218907B (pt)
IE (1)	IE922062A1 (pt)
IL (4)	IL117105A (pt)
LU (1)	LU90939I2 (pt)
MA (1)	MA22563A1 (pt)
MX (1)	MX9203444A (pt)
NL (1)	NL300103I2 (pt)
NO (2)	NO304774B1 (pt)
NZ (1)	NZ243288A (pt)
PL (3)	PL169410B1 (pt)
PT (1)	PT100620B (pt)
RU (1)	RU2137474C1 (pt)
SA (1)	SA92130141B1 (pt)
SG (1)	SG47877A1 (pt)
SI (1)	SI9200125B (pt)
SK (3)	SK280906B6 (pt)
TW (1)	TW214544B (pt)
UA (1)	UA41254C2 (pt)
WO (1)	WO1993000086A1 (pt)
ZA (1)	ZA924658B (pt)

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GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
GB9226530D0 (en) *	1992-12-21	1993-02-17	Smithkline Beecham Plc	Compounds
GB9226566D0 (en) *	1992-12-21	1993-02-17	Smithkline Beecham Plc	Compounds
US5616603A (en) *	1995-05-26	1997-04-01	Smithkline Beecham Plc	Enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5618948A (en) *	1995-05-26	1997-04-08	Smithkline Beecham P.L.C.	Process for preparing an enantiomer of a carbazole derivative
CA2179678A1 (en) *	1995-06-23	1996-12-24	Michael Edward Flaugh	6-substituted-1,2,3,4-tetrahydro-9h-carbazoles and 7-substituted-10h-cyclohepta¬7,6-b\| indoles
US5917054A (en) *	1995-07-18	1999-06-29	Smithkline Beecham P.L.C.	Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5708187A (en) *	1996-06-27	1998-01-13	Eli Lilly And Company	6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
US5891885A (en) *	1996-10-09	1999-04-06	Algos Pharmaceutical Corporation	Method for treating migraine
GB9723061D0 (en) *	1997-10-31	1998-01-07	Vanguard Medica Ltd	Medicaments
US6066092A (en) *	1997-11-06	2000-05-23	Cady; Roger K.	Preemptive prophylaxis of migraine device and method
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
GB9808069D0 (en)	1998-04-16	1998-06-17	Vanguard Medica Ltd	Novel processes
GB9817911D0 (en) *	1998-08-17	1998-10-14	Vanguard Medica Ltd	New use
US20030198669A1 (en) *	2001-07-05	2003-10-23	R.T. Alamo Ventures I, Llc	Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
US6685951B2 (en)	2001-07-05	2004-02-03	R. T. Alamo Ventures I, Inc.	Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US20030017175A1 (en) *	2001-07-05	2003-01-23	R.T. Alamo Ventures I, Inc.	Sublingual administration of dihydroergotamine for the treatment of migraine
WO2003029214A1 (en) *	2001-09-28	2003-04-10	F. Hoffmann-La Roche Ag	Pseudopolymorphic forms of carvedilol
AU2003249582B2 (en)	2002-06-21	2006-08-03	Suven Life Sciences Limited	Tetracyclic arylsulfonyl indoles having serotonin receptor affinity
RU2320663C2 (ru)	2002-06-21	2008-03-27	Сувен Лайф Сайенсиз Лимитед	Новые арилалкилиндолы с аффинностью к серотониновым рецепторам, пригодные в качестве лекарственных средств, способ их получения и содержащие их фармацевтические композиции
PT1567492E (pt)	2002-11-28	2013-07-22	Suven Life Sciences Ltd	N-arilsulfonil-3-aminoalcoxi-indóis
US7875605B2 (en)	2002-11-28	2011-01-25	Suven Life Sciences Limited	N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
SI1581538T1 (sl)	2002-12-18	2007-08-31	Suven Life Sciences Ltd	Tetraciklični 3-substituirani indoli z afiniteto za receptor serotonina
RU2430088C2 (ru) *	2004-07-14	2011-09-27	Центарис Гмбх	Производные тетрагидрокарбазола и фармацевтическая композиция на их основе
US7601856B2 (en)	2006-07-27	2009-10-13	Wyeth	Benzofurans as potassium ion channel modulators
MY147588A (en) *	2006-08-07	2012-12-31	Actelion Pharmaceuticals Ltd	(3-amino-1,2,3,4-tetrahydro-9h-carbazol-9-yl)-acetic acid derivatives
JP2010522135A (ja)	2006-10-09	2010-07-01	チャールストンラボラトリーズ，インコーポレイテッド	医薬組成物
DK2425820T3 (en)	2007-02-11	2015-07-13	Map Pharmaceuticals Inc	A method for the therapeutic administration of DHE in order to enable quick relief of migraine, while minimizing the adverse event profile
US20090069399A1 (en) *	2007-09-12	2009-03-12	Protia, Llc	Deuterium-enriched frovatriptan
JP5714910B2 (ja)	2008-01-09	2015-05-07	チャールストンラボラトリーズ，インコーポレイテッド	薬学的組成物
WO2010073253A1 (en) *	2008-12-22	2010-07-01	Natco Pharma Limited	Method for preparing an optically active frovatriptan
EP3311667A1 (en)	2009-07-08	2018-04-25	Charleston Laboratories, Inc.	Pharmaceutical compositions
US10098674B2 (en)	2009-10-22	2018-10-16	Nuvasive, Inc.	System and method for posterior cervical fusion
WO2011050140A1 (en)	2009-10-22	2011-04-28	Blue Fury Consulting, L.L.C.	Posterior cervical fusion system and techniques
DK2734634T3 (da)	2011-07-22	2019-10-21	Univ Chicago	Igf-1 til anvendelse til behandling af migræne
CA2895816C (en)	2012-12-21	2021-02-23	Map Pharmaceuticals, Inc.	8'-hydroxy-dihydroergotamine compounds and compositions
EP2816030A1 (en)	2013-06-20	2014-12-24	Duke Chem, S. A.	Process for the preparation of frovatriptan and its enantiomer
GB201312768D0 (en)	2013-07-17	2013-08-28	Ge Healthcare Ltd	Work-up procedure
JP2019507181A (ja)	2016-03-04	2019-03-14	チャールストンラボラトリーズ，インコーポレイテッド	医薬組成物
EP3766483A1 (en)	2019-07-19	2021-01-20	BioPharma Synergies, S. L.	Orodispersible powder composition comprising a triptan
WO2025038666A2 (en) *	2023-08-13	2025-02-20	GATC Health Corp	Compounds and methods for treating addiction
CN119499195A (zh) *	2024-11-26	2025-02-25	青岛国信制药有限公司	一种快速吸收琥珀酸呋罗曲坦片及其制备方法

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US3642816A (en) *	1967-08-10	1972-02-15	Sterling Drug Inc	3-acetamido-1 2 3 4-tetrahydrocarbazole
US3959309A (en)	1968-01-24	1976-05-25	Sterling Drug Inc.	3-Amido-1,2,3,4-tetrahydrocarbazoles
US4062864A (en) *	1968-01-24	1977-12-13	Sterling Drug Inc.	3-Hydroxy carbazole derivatives
US3592824A (en) *	1970-03-12	1971-07-13	Miles Lab	3-substituted amino-1,2,3,4-tetrahydrocarbazoles
US4172834A (en) *	1971-08-16	1979-10-30	Sterling Drug Inc.	3-Amino-tetrahydrocarbazoles
BE787537A (fr) *	1971-08-16	1973-02-14	Sterling Drug Inc	Tetrahydrocarbazoles
DE2815926A1 (de) *	1978-04-13	1979-10-18	Boehringer Mannheim Gmbh	Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4257952A (en) *	1977-06-06	1981-03-24	Sterling Drug Inc.	3-Amino-tetrahydrocarbazoles
US4254134A (en) *	1978-03-17	1981-03-03	Endo Laboratories, Inc.	Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles
EP0115607A1 (de) *	1983-01-04	1984-08-15	MERCK PATENT GmbH	Tetrahydrocarbazolderivate

1991
- 1991-06-26 GB GB919113802A patent/GB9113802D0/en active Pending
1992
- 1992-06-17 AT AT92912379T patent/ATE170746T1/de active
- 1992-06-17 EP EP92912379A patent/EP0591280B1/en not_active Expired - Lifetime
- 1992-06-17 UA UA93002251A patent/UA41254C2/uk unknown
- 1992-06-17 US US08/167,846 patent/US5464864A/en not_active Expired - Lifetime
- 1992-06-17 CZ CZ961506A patent/CZ150696A3/cs not_active IP Right Cessation
- 1992-06-17 WO PCT/GB1992/001082 patent/WO1993000086A1/en not_active Ceased
- 1992-06-17 PL PL92307118A patent/PL169410B1/pl unknown
- 1992-06-17 SG SG1996004938A patent/SG47877A1/en unknown
- 1992-06-17 HU HU9303731A patent/HU218907B/hu active IP Right Revival
- 1992-06-17 SK SK1054-98A patent/SK280906B6/sk not_active IP Right Cessation
- 1992-06-17 PL PL92311304A patent/PL171034B1/pl unknown
- 1992-06-17 CA CA002113726A patent/CA2113726C/en not_active Expired - Lifetime
- 1992-06-17 DE DE69226953T patent/DE69226953T2/de not_active Expired - Lifetime
- 1992-06-17 SK SK1319-93A patent/SK280905B6/sk not_active IP Right Cessation
- 1992-06-17 KR KR1019930704055A patent/KR100251571B1/ko not_active Expired - Lifetime
- 1992-06-17 CZ CZ961505A patent/CZ282061B6/cs not_active IP Right Cessation
- 1992-06-17 PL PL92301883A patent/PL169392B1/pl unknown
- 1992-06-17 RU RU93058534A patent/RU2137474C1/ru active Protection Beyond IP Right Term
- 1992-06-17 DE DE2002199042 patent/DE10299042I2/de active Active
- 1992-06-17 SK SK1685-98A patent/SK280907B6/sk not_active IP Right Cessation
- 1992-06-17 JP JP51108692A patent/JP3261502B2/ja not_active Expired - Lifetime
- 1992-06-17 BR BR9206237A patent/BR9206237A/pt not_active Application Discontinuation
- 1992-06-17 CZ CS932861A patent/CZ282083B6/cs not_active IP Right Cessation
- 1992-06-17 DK DK92912379T patent/DK0591280T3/da active
- 1992-06-24 ZA ZA924658A patent/ZA924658B/xx unknown
- 1992-06-24 MA MA22853A patent/MA22563A1/fr unknown
- 1992-06-24 NZ NZ243288A patent/NZ243288A/en not_active IP Right Cessation
- 1992-06-24 PT PT100620A patent/PT100620B/pt not_active IP Right Cessation
- 1992-06-25 IL IL117105A patent/IL117105A/en not_active IP Right Cessation
- 1992-06-25 CN CN92108831A patent/CN1034072C/zh not_active Expired - Lifetime
- 1992-06-25 IL IL117104A patent/IL117104A/xx not_active IP Right Cessation
- 1992-06-25 IL IL102322A patent/IL102322A/xx not_active IP Right Cessation
- 1992-06-25 IL IL11710596A patent/IL117105A0/xx unknown
- 1992-06-25 TW TW081104991A patent/TW214544B/zh not_active IP Right Cessation
- 1992-06-25 AP APAP/P/1992/000403A patent/AP344A/en active
- 1992-06-26 MX MX9203444A patent/MX9203444A/es unknown
- 1992-06-26 SI SI9200125A patent/SI9200125B/sl unknown
- 1992-07-01 IE IE206292A patent/IE922062A1/en not_active IP Right Cessation
- 1992-10-04 SA SA92130141A patent/SA92130141B1/ar unknown
1993
- 1993-12-23 NO NO934759A patent/NO304774B1/no not_active IP Right Cessation
- 1993-12-23 FI FI935842A patent/FI103967B/fi not_active IP Right Cessation
1995
- 1995-05-15 US US08/442,719 patent/US5637611A/en not_active Expired - Lifetime
1997
- 1997-05-06 BR BR1100460-6A patent/BR1100460A/pt active IP Right Grant
2002
- 2002-07-24 LU LU90939C patent/LU90939I2/fr unknown
- 2002-10-14 NL NL300103C patent/NL300103I2/nl unknown
2005
- 2005-05-03 NO NO2005011C patent/NO2005011I2/no unknown

Also Published As

Publication number	Publication date
CZ282083B6 (cs)	1997-05-14
IL117105A0 (en)	1996-06-18
PL169410B1 (pl)	1996-07-31
SK131993A3 (en)	1994-06-08
PL169392B1 (pl)	1996-07-31
SG47877A1 (en)	1998-04-17
EP0591280B1 (en)	1998-09-09
LU90939I2 (fr)	2002-09-24
CZ150596A3 (en)	1997-05-14
HU218907B (hu)	2000-12-28
FI935842A7 (fi)	1993-12-23
IL102322A (en)	1997-09-30
BR1100460A (pt)	2000-07-18
AP9200403A0 (en)	1992-07-31
US5637611A (en)	1997-06-10
MA22563A1 (fr)	1992-12-31
KR100251571B1 (ko)	2000-07-01
HK1014669A1 (en)	1999-09-30
IL117104A0 (en)	1996-06-18
NO2005011I1 (no)	2005-05-18
GB9113802D0 (en)	1991-08-14
US5464864A (en)	1995-11-07
TW214544B (pt)	1993-10-11
EP0591280A1 (en)	1994-04-13
NO2005011I2 (no)	2008-02-11
PT100620B (pt)	1999-01-29
SK280905B6 (sk)	2000-09-12
HUT68961A (en)	1995-08-28
NL300103I2 (nl)	2003-02-03
IL117104A (en)	1997-09-30
IL117105A (en)	1998-01-04
UA41254C2 (uk)	2001-09-17
IL102322A0 (en)	1993-01-14
FI935842A0 (fi)	1993-12-23
MX9203444A (es)	1993-12-01
DE69226953D1 (de)	1998-10-15
CA2113726C (en)	2008-02-19
AP344A (en)	1994-07-05
SI9200125A (en)	1992-12-31
WO1993000086A1 (en)	1993-01-07
SI9200125B (en)	2001-12-31
RU2137474C1 (ru)	1999-09-20
NL300103I1 (nl)	2002-12-02
DE10299042I1 (de)	2003-02-20
SK280907B6 (sk)	2000-09-12
JP3261502B2 (ja)	2002-03-04
NZ243288A (en)	1994-09-27
CA2113726A1 (en)	1993-01-07
FI103967B1 (fi)	1999-10-29
CN1034072C (zh)	1997-02-19
CN1069726A (zh)	1993-03-10
NO934800L (no)	1993-12-23
CZ282327B6 (cs)	1997-06-11
AU1977592A (en)	1993-01-25
ATE170746T1 (de)	1998-09-15
SK280906B6 (sk)	2000-09-12
FI103967B (fi)	1999-10-29
CZ282061B6 (cs)	1997-05-14
JPH06508827A (ja)	1994-10-06
DE10299042I2 (de)	2005-02-03
CZ286193A3 (en)	1994-07-13
IE922062A1 (en)	1992-12-30
ZA924658B (en)	1993-12-24
NO304774B1 (no)	1999-02-15
DK0591280T3 (da)	1999-02-15
DE69226953T2 (de)	1999-05-12
NO934800D0 (no)	1993-12-23
SA92130141B1 (ar)	2005-12-18
AU652842B2 (en)	1994-09-08
PL171034B1 (en)	1997-02-28
PT100620A (pt)	1993-09-30
CZ150696A3 (en)	1997-06-11

Legal Events

Date	Code	Title	Description
1996-09-17	EE	Request for examination
1998-04-28	FA	Application withdrawn

Publication	Publication Date	Title
BR1100460A (pt)	2000-07-18	Uso de derivados de tetrahidrocarbazole como receptores agonistas 5-ht1
FI943247L (fi)	1994-07-07	Piperatsiinijohdannaisia 5-HT-reseptoriantagonisteina
FI973205A7 (fi)	1997-10-01	Indolijohdannaisia 5-HT-reseptoriantagonisteina
KR950700906A (ko)	1995-02-20	5-ht1 작동약으로서의 인돌 유도체(indole derivatives as 5-ht1 agonists)
FI942187A7 (fi)	1994-05-11	Asyklisiä etyleenidiamiinijohdannaisia aine P-reseptoriantagonisteina
FI944729L (fi)	1994-10-07	Perhydroisoindolijohdannaiset substanssi P:n antagonisteina
DK0630376T3 (da)	1999-06-23	Kondenserede indolderivater som 5-HT4-receptorantagonister
DK0901470T3 (da)	2004-07-12	Indolderivater egnede som endothelinreceptorantagonister
DK0856001T3 (da)	2002-12-30	Pyrimidinderivater som 5-HT2C-receptor-antagonister
DE69232003D1 (de)	2001-09-20	Benzanilidderivate als 5-HT1D-Antagonisten
FI960399A7 (fi)	1996-01-29	Perhydroisoindolijohdannaisia P-aineen antagonisteina
FI941178A7 (fi)	1994-03-11	5-HT4-reseptoriantagonisteja
DE69127791D1 (de)	1997-11-06	Diazabicyclononyl-Derivate als 5-HT3 Rezeptor Antagonisten
FI961628A7 (fi)	1996-04-12	Indolijohdannaisia NMDA-antagonisteina
FI962969A7 (fi)	1996-07-25	Indolijohdannaisia 5-HT1:n agonisteina
BR9406435A (pt)	1996-01-09	Utilização de derivados de indol como antagonistas de 5HT1
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