BR9206272A - Derivados de 2-(4-hidroxipiperidino)-1-alcanol, como agentes anti-isquêmicos. - Google Patents

Derivados de 2-(4-hidroxipiperidino)-1-alcanol, como agentes anti-isquêmicos.

Info

Publication number: BR9206272A
Authority: BR; Brazil
Prior art keywords: hydroxypiperidine; alkanol; derivatives; ischemic agents; ischemic
Prior art date: 1991-07-17

Application number

BR9206272A

Other languages

English (en)

Portuguese (pt)

Inventor

Welch Willard Mckowan Jr

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-17

Filing date

1992-06-19

Publication date

1995-04-11

1992-06-19 Application filed by Pfizer filed Critical Pfizer

1995-04-11 Publication of BR9206272A publication Critical patent/BR9206272A/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

BR9206272A 1991-07-17 1992-06-19 Derivados de 2-(4-hidroxipiperidino)-1-alcanol, como agentes anti-isquêmicos. BR9206272A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73157791A	1991-07-17	1991-07-17
PCT/US1992/004973 WO1993002052A1 (en)	1991-07-17	1992-06-19	2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (1)

Publication Number	Publication Date
BR9206272A true BR9206272A (pt)	1995-04-11

Family

ID=24940103

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9206272A BR9206272A (pt)	1991-07-17	1992-06-19	Derivados de 2-(4-hidroxipiperidino)-1-alcanol, como agentes anti-isquêmicos.

Country Status (22)

Country	Link
EP (1)	EP0594729A1 (da)
JP (1)	JP2571904B2 (da)
KR (1)	KR0165003B1 (da)
CN (1)	CN1043759C (da)
AU (1)	AU655840B2 (da)
BR (1)	BR9206272A (da)
CA (1)	CA2113568A1 (da)
CZ (1)	CZ284133B6 (da)
EG (1)	EG20048A (da)
FI (2)	FI981956L (da)
HU (1)	HUT70528A (da)
IE (1)	IE922311A1 (da)
IL (1)	IL102473A (da)
MX (1)	MX9204190A (da)
NO (1)	NO180445C (da)
NZ (1)	NZ243580A (da)
PL (1)	PL169884B1 (da)
PT (1)	PT100689B (da)
RU (1)	RU2065859C1 (da)
TW (1)	TW201732B (da)
WO (1)	WO1993002052A1 (da)
ZA (1)	ZA925306B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5436255A (en) *	1992-07-23	1995-07-25	Pfizer Inc.	Method of treating diseases susceptable to treatment by blocking NMDA-receptors
PL173618B1 (pl) *	1992-10-30	1998-04-30	Pfizer	Związki 6-[2-(4-hydroksy-4-fenylopiperydyno)-1-hydroksypropylo]-3,4-dihydro-2(1H)-chinolonowe
US5498610A (en) *	1992-11-06	1996-03-12	Pfizer Inc.	Neuroprotective indolone and related derivatives
US6978166B2 (en)	1994-10-07	2005-12-20	Saint Louis University	System for use in displaying images of a body part
ZA9610745B (en) *	1995-12-22	1997-06-24	Warner Lambert Co	4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en)	1995-12-22	1997-06-27	Warner Lambert Co	2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610741B (en)	1995-12-22	1997-06-24	Warner Lambert Co	4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en)	1995-12-22	1997-06-24	Warner Lambert Co	Subtype selective nmda receptor ligands and the use thereof
CA2220649C (en) *	1996-12-03	2007-02-13	F. Hoffmann-La Roche Ag	4-hydroxy-piperidine derivatives
CA2369695A1 (en) *	1999-04-09	2000-10-19	Manabu Itoh	Agent for treating neuropathic pain
TWI254043B (en) *	1999-06-08	2006-05-01	Hoffmann La Roche	Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
US6291499B1 (en)	1999-10-29	2001-09-18	Merck & Co., Inc.	2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6432976B1 (en)	1999-10-29	2002-08-13	Merck & Co., Inc.	8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6369076B1 (en)	1999-10-29	2002-04-09	Merck & Co. Inc.	5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
AU1153601A (en)	1999-10-29	2001-05-08	Merck Sharp & Dohme Limited	Method to treat pain utilizing benzimidazole NMDA NR2B antagonists
US6380205B1 (en)	1999-10-29	2002-04-30	Merck & Co., Inc.	2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6489477B1 (en)	1999-10-29	2002-12-03	Merck & Co., Inc.	2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6316474B1 (en)	1999-10-29	2001-11-13	Merck & Co., Inc.	2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6476041B1 (en)	1999-10-29	2002-11-05	Merck & Co., Inc.	1,4 substituted piperidinyl NMDA/NR2B antagonists
US6495561B2 (en)	1999-10-29	2002-12-17	Merck & Co., Inc.	2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
MXPA03007621A (es)	2001-02-23	2003-12-04	Merck & Co Inc	Antagonistas nr2b de n-metil-d-aspartato no arilheterociclicos n-sustituidos.
EP1390034A4 (en)	2001-04-03	2005-07-13	Merck & Co Inc	N-SUBSTITUTED NONARYL HETEROCYCLO AMIDYL-NMDA / NR2B ANTAGONISTS
US7494987B2 (en)	2002-11-25	2009-02-24	Mochida Pharmaceutical Co., Ltd.	Agent for treating respiratory diseases containing 4-hydroxypiperidine derivative as active ingredient
MXPA06003748A (es) *	2003-10-08	2006-06-14	Pfizer	Compuestos de lactama condensada.
TWI409289B (zh)	2010-09-02	2013-09-21	Taiwan Union Technology Corp	由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途
BR112022025900A2 (pt) *	2020-06-23	2023-01-10	Biohaven Therapeutics Ltd	Formulações tópicas de (1s)-1-fenil-2-piridin-2-iletanamina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH17194A (en) *	1980-03-06	1984-06-19	Otsuka Pharma Co Ltd	Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) *	1983-05-19	1985-10-25	Synthelabo	Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) *	1988-07-12	1992-07-10	Synthelabo	Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
EP0398578B1 (en) *	1989-05-17	1997-03-12	Pfizer Inc.	2-piperidino-1-alkanol derivatives as antiischemic agents
EP0554247B1 (en) *	1990-05-10	2000-04-26	Pfizer Inc.	Neuroprotective indolone and related derivatives

1992
- 1992-06-19 AU AU23225/92A patent/AU655840B2/en not_active Ceased
- 1992-06-19 FI FI981956A patent/FI981956L/fi unknown
- 1992-06-19 BR BR9206272A patent/BR9206272A/pt not_active Application Discontinuation
- 1992-06-19 JP JP5502784A patent/JP2571904B2/ja not_active Expired - Lifetime
- 1992-06-19 WO PCT/US1992/004973 patent/WO1993002052A1/en not_active Ceased
- 1992-06-19 EP EP92915510A patent/EP0594729A1/en not_active Ceased
- 1992-06-19 FI FI940192A patent/FI940192A7/fi unknown
- 1992-06-19 CA CA002113568A patent/CA2113568A1/en not_active Abandoned
- 1992-06-19 RU RU9294012366A patent/RU2065859C1/ru active
- 1992-06-19 HU HU9400136A patent/HUT70528A/hu unknown
- 1992-06-19 PL PL92302290A patent/PL169884B1/pl unknown
- 1992-06-19 CZ CS924008A patent/CZ284133B6/cs not_active IP Right Cessation
- 1992-06-23 TW TW081104921A patent/TW201732B/zh active
- 1992-07-12 IL IL102473A patent/IL102473A/xx not_active IP Right Cessation
- 1992-07-15 PT PT100689A patent/PT100689B/pt not_active IP Right Cessation
- 1992-07-16 EG EG39792A patent/EG20048A/xx active
- 1992-07-16 ZA ZA925306A patent/ZA925306B/xx unknown
- 1992-07-16 NZ NZ243580A patent/NZ243580A/en unknown
- 1992-07-16 CN CN92105921A patent/CN1043759C/zh not_active Expired - Fee Related
- 1992-07-16 MX MX9204190A patent/MX9204190A/es unknown
- 1992-07-16 IE IE231192A patent/IE922311A1/en not_active Application Discontinuation
1994
- 1994-01-14 NO NO940144A patent/NO180445C/no not_active IP Right Cessation
- 1994-01-15 KR KR1019940700124A patent/KR0165003B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI940192A0 (fi)	1994-01-14
NZ243580A (en)	1994-10-26
CN1068566A (zh)	1993-02-03
NO180445B (no)	1997-01-13
CN1043759C (zh)	1999-06-23
JP2571904B2 (ja)	1997-01-16
RU2065859C1 (ru)	1996-08-27
PT100689A (pt)	1993-10-29
EP0594729A1 (en)	1994-05-04
IL102473A (en)	1997-07-13
NO180445C (no)	1997-04-23
JPH06504293A (ja)	1994-05-19
EG20048A (en)	1997-03-27
CZ284133B6 (cs)	1998-08-12
IE922311A1 (en)	1993-01-27
NO940144D0 (no)	1994-01-14
ZA925306B (en)	1994-01-17
FI981956A0 (fi)	1998-09-11
CZ400892A3 (en)	1994-03-16
FI940192L (fi)	1994-01-14
IL102473A0 (en)	1993-01-14
PT100689B (pt)	1999-06-30
FI981956A7 (fi)	1998-09-11
TW201732B (da)	1993-03-11
CA2113568A1 (en)	1993-02-04
MX9204190A (es)	1993-01-01
KR0165003B1 (en)	1999-01-15
FI981956L (fi)	1998-09-11
WO1993002052A1 (en)	1993-02-04
FI940192A7 (fi)	1994-01-14
HUT70528A (en)	1995-10-30
AU655840B2 (en)	1995-01-12
PL169884B1 (pl)	1996-09-30
AU2322592A (en)	1993-02-23
NO940144L (no)	1994-01-14
HU9400136D0 (en)	1994-05-30

Legal Events

Date	Code	Title
1995-06-27	EE	Request for examination
1999-02-02	EG	Technical examination (opinion): publication of technical examination (opinion)
1999-08-31	FC	Decision: refusal
2000-03-08	FC	Decision: refusal

Publication	Publication Date	Title
PT100689A (pt)	1993-10-29	Derivados de 2-(4-hidroxipiperidino)-1-alcanol como agentes anti-isquemicos
FI914163L (fi)	1992-03-26	Heterocykliska derivat.
DE69017066D1 (de)	1995-03-30	3-Substituierte-2-Oxindolderivate als Entzündungshemmender.
FI921560L (fi)	1992-04-08	Heterosykliska foereningar.
DE59108494D1 (de)	1997-03-06	1-H-3-Aryl-pyrrolidin-2,4-dion-Derivate
NL300035I2 (nl)	2001-07-02	Gesubstitueerde thiazolidinedionderivaten.
MX9204425A (es)	1993-01-01	Derivados de quinazolina como inhibidores de la acetilcolinesterasa.
DE59100656D1 (de)	1994-01-13	Bohrfutter.
DE59101925D1 (de)	1994-07-21	Bohrfutter.
MX9205678A (es)	1993-04-01	Heteroarilaminas como nuevos inhibidores de la acetilcolinesterasa.
FI942635A7 (fi)	1994-06-03	Piperatsiinijohdannaiset 5HT1A-antagonisteina
FI910503A7 (fi)	1991-08-03	Nya heterocykliska derivat.
FI920564L (fi)	1992-08-12	Heterocykliska kvaevefoereningar.
FI893381A7 (fi)	1990-01-13	Heterocykliska foereningar.
BR9609849B1 (pt)	2010-05-18	derivados de 2-(4-substituìda) -benzilamino-2-metila-propanamida.
FI910750A7 (fi)	1991-08-17	Heterocykliska foereningar.
FI932173L (fi)	1993-05-13	4-(1,2-benzisoxazolyl)piperidinantipsykotiska medel
TR27090A (tr)	1994-10-18	Tetrahidropirimidin türevleri.
FI920121L (fi)	1992-07-15	Foerfarande foer framstaellning av heterocykliska hydroxylaminer.
FI923016L (fi)	1992-06-29	Preparat med enzymatisk delignifieringsaktivitet, foerfarande foer dess framstaellning, och dess anvaendningar.
FI914910L (fi)	1992-04-19	Heterocykliska foereningar.
DK101689D0 (da)	1989-03-02	4-substituerede pyrazolooe3,4-daapyrimidinderivater
FI875101L (fi)	1988-06-04	Laktamderivat och preparat innehaollande dessa.
ATE119146T1 (de)	1995-03-15	Substituierte bicycloheptadionderivate.
IT9053313U1 (it)	1991-04-19	Scorrevole per cassetti.