BR9508765A - Vacina viva para o tratamento de tumores - Google Patents

Vacina viva para o tratamento de tumores

Info

Publication number: BR9508765A
Authority: BR; Brazil
Prior art keywords: vaccine; cells; pct; tumour; cell
Prior art date: 1994-08-24

Application number

BR9508765A

Other languages

English (en)

Inventor

Thomas Blankenstein

Sophie Cayeux Pezzutto

Original Assignee

Max Delbrueck Centrum

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-08-24

Filing date

1995-08-18

Publication date

1997-11-11

1995-08-18 Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum

1997-11-11 Publication of BR9508765A publication Critical patent/BR9508765A/pt

Links

229960005486 vaccine Drugs 0.000 title abstract 9
206010028980 Neoplasm Diseases 0.000 title abstract 2
210000004027 cell Anatomy 0.000 abstract 5
108090000623 proteins and genes Proteins 0.000 abstract 5
229940030156 cell vaccine Drugs 0.000 abstract 3
230000003308 immunostimulating effect Effects 0.000 abstract 3
210000004881 tumor cell Anatomy 0.000 abstract 3
108020004440 Thymidine kinase Proteins 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
238000010353 genetic engineering Methods 0.000 abstract 2
102000018697 Membrane Proteins Human genes 0.000 abstract 1
108010052285 Membrane Proteins Proteins 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000002068 genetic effect Effects 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
239000003550 marker Substances 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001136—Cytokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5418—IL-7
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70532—B7 molecules, e.g. CD80, CD86
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Mycology (AREA)
Oncology (AREA)
Cell Biology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

BR9508765A 1994-08-24 1995-08-18 Vacina viva para o tratamento de tumores BR9508765A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4431401A DE4431401A1 (de)	1994-08-24	1994-08-24	Lebendvakzine gegen Tumorerkrankungen
PCT/DE1995/001164 WO1996005866A2 (de)	1994-08-24	1995-08-18	Lebendvakzine zur behandlung von tumorerkrankungen

Publications (1)

Publication Number	Publication Date
BR9508765A true BR9508765A (pt)	1997-11-11

Family

ID=6527332

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9508765A BR9508765A (pt)	1994-08-24	1995-08-18	Vacina viva para o tratamento de tumores

Country Status (13)

Country	Link
US (1)	US6039941A (pt)
EP (1)	EP0777499B1 (pt)
JP (1)	JP2975117B2 (pt)
KR (1)	KR970705416A (pt)
AT (1)	ATE228016T1 (pt)
AU (1)	AU688101B2 (pt)
BR (1)	BR9508765A (pt)
CA (1)	CA2198234A1 (pt)
DE (3)	DE4431401A1 (pt)
DK (1)	DK0777499T3 (pt)
ES (1)	ES2187568T3 (pt)
PT (1)	PT777499E (pt)
WO (1)	WO1996005866A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7361332B2 (en)	1995-03-17	2008-04-22	The Regents Of The University Of California	Treating tumors using implants comprising combinations of allogeneic cells
US5952221A (en) *	1996-03-06	1999-09-14	Avigen, Inc.	Adeno-associated virus vectors comprising a first and second nucleic acid sequence
DE19626830A1 (de) *	1996-07-04	1998-01-08	Max Delbrueck Centrum	Konditionales Immortalisationsverfahren für humane Tumorzellen zur Herstellung einer Vakzine
US6277368B1 (en)	1996-07-25	2001-08-21	The Regents Of The University Of California	Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
ATE229810T1 (de)	1996-10-11	2003-01-15	Univ California	Krebs immuntherapie unter verwendung von tumorzellen kombiniert mit lymphozytmischungen
AUPQ755300A0 (en)	2000-05-17	2000-06-08	Monash University	Immune potentiating compositions
AU785241B2 (en) *	2000-05-17	2006-11-23	Cancure Limited	Immune potentiating compositions
AU2003281200A1 (en) *	2002-07-03	2004-01-23	Tasuku Honjo	Immunopotentiating compositions
GB0223696D0 (en) *	2002-10-14	2002-11-20	Ml Lab Plc	Improved immunotherapy
JP2006096663A (ja) *	2002-10-17	2006-04-13	Sangaku Renkei Kiko Kyushu:Kk	癌遺伝子ワクチン
GB0227989D0 (en) *	2002-12-02	2003-01-08	Imp College Innovations Ltd	Chimaeric molecules
US20130052215A9 (en)	2003-09-26	2013-02-28	Eckhard Podack	Tumor vaccine
CA2540283C (en) *	2003-09-26	2019-05-21	University Of Miami	Tumor vaccine
PL1699480T3 (pl) *	2003-12-30	2011-11-30	Mologen Ag	Allogeniczny przeciwnowotworowy czynnik terapeutyczny
EA200700598A1 (ru)	2007-03-07	2007-12-28	Петр Генриевич ЛОХОВ	Противоопухолевая вакцина, способ получения противоопухолевой вакцины и способ проведения противоопухолевой иммунотерапии
US8741315B2 (en)	2007-09-12	2014-06-03	Yeda Research And Development Co. Ltd.	Methods of treating tumors in immune-privileged sites
RU2407789C2 (ru) *	2008-07-25	2010-12-27	Виктор Владимирович Кешелава	Способ получения живой клеточной вакцины для профилактики рака молочных желез
EA011421B1 (ru) *	2008-08-26	2009-02-27	Петр Генриевич ЛОХОВ	Способ получения противоопухолевой вакцины
CN111743884A (zh) *	2019-03-26	2020-10-09	深圳先进技术研究院	苄丝肼或其衍生物的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI91713C (fi) *	1992-04-23	1994-08-10	Axidental Oy	Uusia bioaktiivisia pinnotteita ja niiden valmistus ja käyttö
WO1993021959A1 (en) *	1992-05-01	1993-11-11	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Bystander effect tumoricidal therapy
WO1994004196A1 (en) *	1992-08-14	1994-03-03	Imperial Cancer Research Technology Limited	Tumour therapy

1994
- 1994-08-24 DE DE4431401A patent/DE4431401A1/de not_active Withdrawn
1995
- 1995-08-18 DK DK95929003T patent/DK0777499T3/da active
- 1995-08-18 ES ES95929003T patent/ES2187568T3/es not_active Expired - Lifetime
- 1995-08-18 AT AT95929003T patent/ATE228016T1/de not_active IP Right Cessation
- 1995-08-18 JP JP8507710A patent/JP2975117B2/ja not_active Expired - Fee Related
- 1995-08-18 WO PCT/DE1995/001164 patent/WO1996005866A2/de not_active Ceased
- 1995-08-18 US US08/793,104 patent/US6039941A/en not_active Expired - Fee Related
- 1995-08-18 AU AU32531/95A patent/AU688101B2/en not_active Ceased
- 1995-08-18 CA CA002198234A patent/CA2198234A1/en not_active Abandoned
- 1995-08-18 BR BR9508765A patent/BR9508765A/pt unknown
- 1995-08-18 PT PT95929003T patent/PT777499E/pt unknown
- 1995-08-18 DE DE19580890T patent/DE19580890D2/de not_active Ceased
- 1995-08-18 EP EP95929003A patent/EP0777499B1/de not_active Expired - Lifetime
- 1995-08-18 DE DE59510466T patent/DE59510466D1/de not_active Expired - Lifetime
- 1995-08-18 KR KR1019970701175A patent/KR970705416A/ko not_active Ceased

Also Published As

Publication number	Publication date
AU3253195A (en)	1996-03-14
MX9701384A (es)	1998-03-31
DE4431401A1 (de)	1996-02-29
KR970705416A (ko)	1997-10-09
ATE228016T1 (de)	2002-12-15
DK0777499T3 (da)	2003-03-17
JP2975117B2 (ja)	1999-11-10
US6039941A (en)	2000-03-21
WO1996005866A3 (de)	1996-04-11
EP0777499A1 (de)	1997-06-11
EP0777499B1 (de)	2002-11-20
AU688101B2 (en)	1998-03-05
DE19580890D2 (de)	1997-06-19
WO1996005866A2 (de)	1996-02-29
JPH10505339A (ja)	1998-05-26
PT777499E (pt)	2003-03-31
ES2187568T3 (es)	2003-06-16
DE59510466D1 (de)	2003-01-02
CA2198234A1 (en)	1996-02-29

Legal Events

Date	Code	Title	Description
2005-02-22	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Publication	Publication Date	Title
BR9508765A (pt)	1997-11-11	Vacina viva para o tratamento de tumores
AP2003002937A0 (en)	2003-12-31	One dose vaccination with mycoplasma hyopneumoniae
ES2167365T3 (es)	2002-05-16	Vectores adenovirales de origen animal y utilizacion en terapia genica.
MX9700229A (es)	1997-04-30	Vacuna de polinucleotido para virus de papiloma.
EP1322755A4 (en)	2006-04-05	BY PHAGENDISPLAY IDENTIFIED TARGETS OF PEOPLE AND MOUSE
GR3020557T3 (en)	1996-10-31	Oligonucleotide alkylphosphonates and alkylphosphonothioates.
DK0784483T3 (da)	2001-03-26	Præparat indeholdende et rekombinant virus, der udtrykker et antigen, og et rekombinant virus, der udtrykker et immunstimul
DE3878468D1 (de)	1993-03-25	Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.
MXPA03011815A (es)	2004-04-02	Vacuna de micoplasma bovis y metodos para reducir la neumonia en animales.
DE69434244D1 (de)	2005-03-03	Verbesserte krebstherapie
BRPI0418157A (pt)	2007-04-17	terapêutica de tumores alogênicos
MY209484A (en)	2025-07-11	Cpg amphiphiles and uses thereof
BR0109928A (pt)	2003-05-27	Uso de um herpes vìrus atenuado, e, método para estimular uma resposta imune em um indivìduo humano ou animal, ou para tratar ou prevenir uma infecção patogênica ou câncer em um indivìduo humano ou animal
FR2746110B1 (fr)	1998-04-17	Methode de traitement par therapie genique des tumeurs humaines et virus recombinants correspondants
BR0313413A (pt)	2005-07-12	Uso da vacinação beta amilóide juntamente com um inibidor da cox-2 seletivo para o tratamento da doença de alzheimer
MXPA02005506A (es)	2004-09-10	Clonacion de un gen que codifica una racemasa de aminoacido derivada de tripanosoma cruzi, y usos del mismo.
CY1111522T1 (el)	2015-08-05	84p2a9: ειδικη σε προστατη και ορχεις πρωτεϊνη που εκφραζεται σε υψηλο βαθμο στον προστατικο καρκινο
ATE310747T1 (de)	2005-12-15	Impfstoff gegen geflügelkokzidose
BR0311371A (pt)	2005-04-05	Composições para uso terapêutico compreendendo uma vitamina, um sal de metal e insulina ou um hormÈnio de crescimento
BR0209145A (pt)	2005-04-19	Vacina contra varìola
BR0012985A (pt)	2003-09-16	Vacina, bactéria, uso da mesma, e composição farmacêutica e métodos de tratamento ou prevenção de doença mediada por hsv em um hospedeiro humano ou animal e de uma infecção viral da mucosa de um hospedeiro humano ou animal
BRPI0112407B8 (pt)	2021-05-25	uso de cepas de parapoxvírus ovis para produzir medicamentos antivirais e medicamentos contra câncer
MX9708615A (es)	1998-06-28	Terapia de genes animales.
UA90838C2 (ru)	2010-06-10	Рекомбинантный поксвирус, который экспрессирует гомологические гены, вставленные в поксвирусный геном
BR9805717A (pt)	2000-09-12	Shampoo universal