BR9606566A - Material viral no estado isolado ou purificado fragmento de nicliotideos sonda nucleica de detecção de um agente patógeno e/ou infeccioso iniciador para a amplificação por polimerização de uma rna ou um dna de material viral rna ou dna e notadamente vetor de replicação peptideo anticorpo mono- ou policlonal reativo de detecção de virus-1 ou de uma exposição do referido virus composição diagnóstica profilática ou terapéutica processos para detectar um agente patológico e/ou infeccioso e a presenç - Google Patents

Material viral no estado isolado ou purificado fragmento de nicliotideos sonda nucleica de detecção de um agente patógeno e/ou infeccioso iniciador para a amplificação por polimerização de uma rna ou um dna de material viral rna ou dna e notadamente vetor de replicação peptideo anticorpo mono- ou policlonal reativo de detecção de virus-1 ou de uma exposição do referido virus composição diagnóstica profilática ou terapéutica processos para detectar um agente patológico e/ou infeccioso e a presenç

Info

Publication number
BR9606566A
BR9606566A BR9606566A BR9606566A BR9606566A BR 9606566 A BR9606566 A BR 9606566A BR 9606566 A BR9606566 A BR 9606566A BR 9606566 A BR9606566 A BR 9606566A BR 9606566 A BR9606566 A BR 9606566A
Authority
BR
Brazil
Prior art keywords
dna
rna
virus
viral material
detecting
Prior art date
Application number
BR9606566A
Other languages
English (en)
Portuguese (pt)
Inventor
Herve Perron
Frederic Beseme
Frederic Bedin
Glaucia Paranhos-Baccala
Florence Komurian-Prodel
Colette Jolivet-Reynaud
Bernard Mandrand
Original Assignee
Bio Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux filed Critical Bio Merieux
Publication of BR9606566A publication Critical patent/BR9606566A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
BR9606566A 1995-08-03 1996-08-02 Material viral no estado isolado ou purificado fragmento de nicliotideos sonda nucleica de detecção de um agente patógeno e/ou infeccioso iniciador para a amplificação por polimerização de uma rna ou um dna de material viral rna ou dna e notadamente vetor de replicação peptideo anticorpo mono- ou policlonal reativo de detecção de virus-1 ou de uma exposição do referido virus composição diagnóstica profilática ou terapéutica processos para detectar um agente patológico e/ou infeccioso e a presenç BR9606566A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9509643A FR2737500B1 (fr) 1995-08-03 1995-08-03 Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques
PCT/FR1996/001244 WO1997006260A1 (fr) 1995-08-03 1996-08-02 Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques

Publications (1)

Publication Number Publication Date
BR9606566A true BR9606566A (pt) 1997-12-30

Family

ID=9481811

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9606566A BR9606566A (pt) 1995-08-03 1996-08-02 Material viral no estado isolado ou purificado fragmento de nicliotideos sonda nucleica de detecção de um agente patógeno e/ou infeccioso iniciador para a amplificação por polimerização de uma rna ou um dna de material viral rna ou dna e notadamente vetor de replicação peptideo anticorpo mono- ou policlonal reativo de detecção de virus-1 ou de uma exposição do referido virus composição diagnóstica profilática ou terapéutica processos para detectar um agente patológico e/ou infeccioso e a presenç

Country Status (19)

Country Link
US (4) US6001987A (2)
EP (2) EP0789077B1 (2)
JP (2) JP4444372B2 (2)
AT (2) ATE541933T1 (2)
AU (1) AU730080B2 (2)
BG (1) BG62977B1 (2)
BR (1) BR9606566A (2)
CA (1) CA2201282C (2)
CZ (1) CZ135797A3 (2)
DE (1) DE69637264T2 (2)
ES (2) ES2293645T3 (2)
FR (1) FR2737500B1 (2)
HU (1) HUP9900425A3 (2)
IS (1) IS4455A (2)
NO (1) NO971493L (2)
NZ (1) NZ316080A (2)
PL (1) PL319512A1 (2)
SK (1) SK56797A3 (2)
WO (1) WO1997006260A1 (2)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2737500B1 (fr) * 1995-08-03 1997-08-29 Bio Merieux Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques
US7241876B2 (en) 1996-01-11 2007-07-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6759217B2 (en) * 1996-03-26 2004-07-06 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US8043835B1 (en) 1996-03-26 2011-10-25 Oncomedx, Inc. Methods for detecting and monitoring cancer using extracellular RNA
CA2250118C (en) * 1996-03-26 2009-09-29 Michael S. Kopreski Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer
US7785842B2 (en) * 1996-03-26 2010-08-31 Oncomedx, Inc. Comparative analysis of extracellular RNA species
JP4044142B2 (ja) * 1996-10-04 2008-02-06 ビー. アーノビッツ,ハワード 核酸の診断検出
EP0942987B1 (en) * 1996-11-26 2009-08-19 Bio Merieux Viral material and nucleotide fragments associated with multiple sclerosis, for diagnostic, prophylactic and therapeutic purposes
US20070009934A1 (en) * 1997-03-14 2007-01-11 Kopreski Michael S Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US8440396B2 (en) * 1997-03-14 2013-05-14 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
FR2762600B1 (fr) * 1997-04-29 1999-11-05 Bio Merieux Polypeptide capable de reagir avec les anticorps de patients atteints de sclerose en plaques et utlisations
FR2762601B3 (fr) * 1997-04-29 1999-06-04 Bio Merieux Polypeptide capable de reagir avec les anticorps de patients atteints de sclerose en plaques et utilisations
FR2765588A1 (fr) 1997-07-07 1999-01-08 Bio Merieux Materiel nucleique retroviral et fragments nucleotidiques notamment associes a la sclerose en plaques et/ou la polyarthrite rhumatoide, a des fins de diagnostic, prophylactiques et therapeutiques
US20040176314A1 (en) * 1997-07-07 2004-09-09 Bio Merieux Endogenetic retroviral sequences, associated with autoimmune diseases or with pregnancy disorders
WO1999002696A1 (fr) * 1997-07-07 1999-01-21 Bio Merieux Sequences retroviraux endogenes, associees a des maladies auto-immunes et/ou a des perturbations de la grossesse
AU2922399A (en) * 1998-04-08 1999-11-01 Ms Research A/S Diagnosis of multiple sclerosis and other demyelinating diseases
FR2780069B1 (fr) * 1998-06-23 2002-06-28 Inst Nat Sante Rech Med Famille de sequences nucleiques et de sequences proteiques deduites presentant des motifs retroviraux endogenes humains et leurs applications
US8163524B2 (en) * 1998-09-22 2012-04-24 Oncomedx, Inc. Comparative analysis of extracellular RNA species
US20060204989A1 (en) * 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
US20080261292A1 (en) * 1998-09-22 2008-10-23 Oncomedx, Inc. Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions
FR2788784A1 (fr) * 1999-01-21 2000-07-28 Bio Merieux Fragment nucleique endogene associe a une maladie auto-immune, procede de marquage et reactif
EP1029917A1 (en) * 1999-02-15 2000-08-23 Bio Merieux The LTR region of MSRV-1 and the proteins it encodes, and probes and methods for detecting MSRV-1 retrovirus
JP2003507070A (ja) * 1999-08-20 2003-02-25 キュラジェン コーポレイション 活性化tリンパ球において発現される新規なポリヌクレオチドおよびそれによってコードされるタンパク質
DE10012875B4 (de) * 2000-03-16 2004-04-01 Infineon Technologies Ag Mobilfunkempfänger
EP1265989A2 (en) * 2000-03-21 2002-12-18 MS Research A/S An infective endogenous retrovirus in association with demyelinating diseases e.g. multiple sclerosis
ES2367280T3 (es) * 2001-07-25 2011-11-02 Oncomedx Inc. Métodos para evaluar estados patológicos usando arn extracelular.
US20100159464A1 (en) * 2001-11-05 2010-06-24 Oncomedx, Inc. Method for Detection of DNA Methyltransferase RNA in Plasma and Serum
US20030104454A1 (en) * 2001-11-05 2003-06-05 Kopreski Michael S. Method for detection of DNA methyltransferase RNA in plasma and serum
US20090136942A1 (en) * 2007-09-18 2009-05-28 Oncomedx, Inc. Analysis of Extracellular RNA
US8680065B2 (en) * 2008-09-11 2014-03-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Oligonucleotides of human endogenous retrovirus 9 (ERV-9) long terminal repeat (LTR) and methods of use

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346074A (en) * 1978-08-24 1982-08-24 National Research Development Corp. Pasteurellosis vaccines
US4311686A (en) * 1979-04-30 1982-01-19 The Immunology Development Corporation Methodology for the immunodiagnosis of multiple sclerosis and/or malignant diseases from blood sample analysis
US4396600A (en) * 1980-12-18 1983-08-02 Gus Gallucci Adult schistosome worm-derived antigenic substance and method of obtaining same
US4388298A (en) * 1982-07-14 1983-06-14 The United States Of America As Represented By The Secretary Of Agriculture Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced
GB8324800D0 (en) * 1983-09-15 1983-10-19 Pasteur Institut Antigens
US4647773A (en) * 1984-04-23 1987-03-03 The United States Of America As Represented By The Department Of Health And Human Services Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS
US4520113A (en) * 1984-04-23 1985-05-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions
NZ218050A (en) * 1985-11-13 1989-05-29 Wistar Inst Test for the presence of htlv-1v
US4900553A (en) * 1987-09-11 1990-02-13 Case Western Reserve University Method of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes
EP0326395A2 (en) * 1988-01-29 1989-08-02 City Of Hope Method of detecting and identifying certain viral sequences
FR2651581B1 (fr) * 1989-09-06 1994-05-13 Centre Nal Recherc Scientifique Moyens pour le diagnostic de neuropathies demyelinisantes, en particulier de la sclerose en plaques.
US5219837A (en) * 1990-06-21 1993-06-15 Trustees Of The University Of Pennsylvania Method of stimulating myelination of cells
US5158976A (en) * 1990-10-29 1992-10-27 The Children's Medical Center Corporation Controlling glutamine/glutamate related neuronal injury
EP0575491B1 (en) * 1991-03-07 2003-08-13 Virogenetics Corporation Genetically engineered vaccine strain
DK173091D0 (da) * 1991-10-11 1991-10-11 Schleroseforeningen The Danish Biologisk materiale
FR2689521B1 (fr) * 1992-04-03 1996-07-19 Bio Merieux Procede d'obtention et maintien d'une culture cellulaire viable, infectee par un virus associe a la sclerose en plaques, et produits biologiques derives de ladite culture.
FR2689520B1 (fr) 1992-04-03 1996-07-19 Bio Merieux Procede et milieu de culture pour l'obtention de cellules infectees par un virus associe a la sclerose en plaques.
CA2117893A1 (en) * 1992-05-18 1993-11-25 Paul J. Godowski Variant dimers for receptor activation
GB9310657D0 (en) * 1993-05-24 1993-07-07 Univ London Retrovirus
US5580766A (en) * 1994-01-14 1996-12-03 Alexion Pharmaceuticals, Inc. Retroviral vector particles for transducing non-proliferating cells
AU704440B2 (en) * 1994-02-04 1999-04-22 Bio Merieux MSRV1 virus and MSRV2 pathogenic and/or infectious agent associated with multiple sclerosis, nucleic acid components and applications of same
US5691147A (en) * 1994-06-02 1997-11-25 Mitotix, Inc. CDK4 binding assay
US5710037A (en) * 1994-06-10 1998-01-20 The United States Of America As Represented By The Department Of Health And Human Services Retroviral vector particles
FR2731356B1 (fr) * 1995-03-09 1997-04-30 Bio Merieux Virus msrv-1 et agent pathogene et/ou infectant msrv-2 associes a la polyarthrite rhumatoide
FR2737500B1 (fr) * 1995-08-03 1997-08-29 Bio Merieux Materiel viral et fragments nucleotidiques associes a la sclerose en plaques, a des fins de diagnostic, prophylactiques et therapeutiques

Also Published As

Publication number Publication date
JP4444372B2 (ja) 2010-03-31
EP0789077A1 (fr) 1997-08-13
SK56797A3 (en) 1998-09-09
NO971493D0 (no) 1997-04-02
FR2737500A1 (fr) 1997-02-07
US20070117189A1 (en) 2007-05-24
FR2737500B1 (fr) 1997-08-29
PL319512A1 (en) 1997-08-18
CZ135797A3 (cs) 1998-06-17
CA2201282A1 (fr) 1997-02-20
EP0789077B1 (fr) 2007-09-26
BG101355A (en) 1997-12-30
ES2293645T3 (es) 2008-03-16
US20030186391A1 (en) 2003-10-02
EP1916304A2 (fr) 2008-04-30
AU6823296A (en) 1997-03-05
CA2201282C (fr) 2013-04-02
US6579526B1 (en) 2003-06-17
JP5143814B2 (ja) 2013-02-13
JP2010047604A (ja) 2010-03-04
EP1916304A3 (fr) 2008-05-07
US7932350B2 (en) 2011-04-26
JPH11502416A (ja) 1999-03-02
ATE541933T1 (de) 2012-02-15
BG62977B1 (bg) 2000-12-29
ATE374252T1 (de) 2007-10-15
US6001987A (en) 1999-12-14
IS4455A (is) 1997-03-26
EP1916304B1 (fr) 2012-01-18
HUP9900425A2 (hu) 1999-05-28
NZ316080A (en) 1999-04-29
NO971493L (no) 1997-06-03
DE69637264T2 (de) 2008-06-26
WO1997006260A1 (fr) 1997-02-20
HUP9900425A3 (en) 1999-11-29
AU730080B2 (en) 2001-02-22
DE69637264D1 (de) 2007-11-08
ES2379011T3 (es) 2012-04-19

Similar Documents

Publication Publication Date Title
IS4455A (is) Veiruefni og kirnisbrot tengd MS sjúkdómi sem nýta má til sjúkdómsgreiningar, hindrunar og lækningar
Saltarelli et al. Nucleotide sequence and transcriptional analysis of molecular clones of CAEV which generate infectious virus
Stahl et al. Detection of multiple viral DNA species in synovial tissue and fluid of patients with early arthritis
Mager et al. HERV-H endogenous retroviruses: presence in the New World branch but amplification in the Old World primate lineage
Contreras-Galindo et al. Detection of HERV-K (HML-2) viral RNA in plasma of HIV type 1-infected individuals
Furukawa et al. Human T-cell leukemia virus type-1 (HTLV-1) Tax is expressed at the same level in infected cells of HTLV-1-associated myelopathy or tropical spastic paraparesis patients as in asymptomatic carriers but at a lower level in adult T-cell leukemia cells
USRE37918E1 (en) Nucleic acid derivatives
JP2019504868A5 (2)
Kovalskaya et al. Functional human endogenous retroviral LTR transcription start sites are located between the R and U5 regions
Hayashi et al. Elucidation of a conserved RNA stem-loop structure in the packaging signal of human immunodeficiency virus type 1
Bangham et al. PCR analysis of DNA from multiple sclerosis patients for the presence of HTLV-I
Pathak et al. “Might as well jump!” Template switching by retroviral reverse transcriptase, defective genome formation, and recombination
Zignego et al. Amplification of hepatitis delta virus RNA sequences by polymerase chain reaction: a tool for viral detection and cloning
Nelson et al. Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection
JP2022527412A5 (2)
Zheng et al. Insertions, duplications and substitutions in restricted gp90 regions of equine infectious anaemia virus during febrile episodes in an experimentally infected horse
Cristillo et al. Double-stranded RNA as a not-self alarm signal: to evade, most viruses purine-load their RNAs, but some (HTLV-1, Epstein-Barr) pyrimidine-load
Frouard et al. HIV-seq reveals gene expression differences between HIV-transcribing cells from viremic and suppressed people with HIV
Naghavi et al. Upstream stimulating factor affects human immunodeficiency virus type 1 (HIV-1) long terminal repeat-directed transcription in a cell-specific manner, independently of the HIV-1 subtype and the core-negative regulatory element
Hunt et al. Occurrence of additional NF-kappaB-binding motifs in the long terminal repeat region of South African HIV type 1 subtype C isolates
Rigby et al. Human retrovirus‐5 proviral DNA is rarely detected in salivary gland biopsy tissues from patients with Sjögren's syndrome
Kim et al. Genomic variation and segregation of equine infectious anemia virus during acute infection
CA2406830A1 (en) Method for mutation detection in hiv using pol sequencing
Lu et al. Virus–host mucosal interactions during early SIV rectal transmission
Bredell et al. Identification of HIV type 1 intersubtype recombinants in South Africa using env and gag heteroduplex mobility assays

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]