BR9708263A - Hidrogéis de alto ìndice de refração preparados de polìmeros e copolìmeros de n-benzil-n-metil acrilamida. - Google Patents

Hidrogéis de alto ìndice de refração preparados de polìmeros e copolìmeros de n-benzil-n-metil acrilamida.

Info

Publication number
BR9708263A
BR9708263A BR9708263-5A BR9708263A BR9708263A BR 9708263 A BR9708263 A BR 9708263A BR 9708263 A BR9708263 A BR 9708263A BR 9708263 A BR9708263 A BR 9708263A
Authority
BR
Brazil
Prior art keywords
benzyl
high refractive
copolymers
refractive index
methyl acrylamide
Prior art date
Application number
BR9708263-5A
Other languages
English (en)
Inventor
Xiugao Liao
Yading Wang
Stephen Q Zhou
Original Assignee
Pharmacia Iovision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Iovision Inc filed Critical Pharmacia Iovision Inc
Publication of BR9708263A publication Critical patent/BR9708263A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52—Amides or imides
    • C08F20/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/924—Material characteristic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Eyeglasses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"HIDROGéIS DE ALTO ìNDICE DE REFRAçãO PREPARADOS DE POLìMEROS E COPOLìMEROS DE N-BENZIL-N-METIL ACRILAMIDA". Novos hidrogéis de alta resistência, biocompatíveis, úteis em lentes intraoculares são providos os quais são oticamente transparentes, têm altos índices de refração e possuem estabilidade de longo termo. Os hidrogéis são preparados a partir de copolímeros reticulados de N-benzil-N-metil acrilamida.
BR9708263-5A 1996-03-25 1997-03-17 Hidrogéis de alto ìndice de refração preparados de polìmeros e copolìmeros de n-benzil-n-metil acrilamida. BR9708263A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/622,527 US5717049A (en) 1996-03-25 1996-03-25 High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide
PCT/IB1997/000348 WO1997035896A1 (en) 1996-03-25 1997-03-17 High refractive index hydrogels prepared from polymers and copolymers of n-benzyl-n-methylacrylamide

Publications (1)

Publication Number Publication Date
BR9708263A true BR9708263A (pt) 2000-01-04

Family

ID=24494514

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708263-5A BR9708263A (pt) 1996-03-25 1997-03-17 Hidrogéis de alto ìndice de refração preparados de polìmeros e copolìmeros de n-benzil-n-metil acrilamida.

Country Status (15)

Country Link
US (1) US5717049A (pt)
EP (1) EP0889916B1 (pt)
JP (1) JP2000507298A (pt)
KR (1) KR100482946B1 (pt)
CN (1) CN1103786C (pt)
AT (1) ATE239758T1 (pt)
AU (1) AU712171B2 (pt)
BR (1) BR9708263A (pt)
CA (1) CA2249991A1 (pt)
DE (1) DE69721750T2 (pt)
DK (1) DK0889916T3 (pt)
ES (1) ES2200160T3 (pt)
NZ (1) NZ331946A (pt)
PT (1) PT889916E (pt)
WO (1) WO1997035896A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329485B1 (en) 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants
AUPP939299A0 (en) 1999-03-23 1999-04-15 University Of Melbourne, The Polymer gels and methods for their preparation
WO2003051408A1 (en) * 2001-12-19 2003-06-26 First Water Limited Hydrogel compositions comprising an acryloyl morpholine polymer
US20030223954A1 (en) * 2002-05-31 2003-12-04 Ruscio Dominic V. Polymeric materials for use as photoablatable inlays
US6737448B2 (en) * 2002-06-03 2004-05-18 Staar Surgical Company High refractive index, optically clear and soft hydrophobic acrylamide copolymers
JP4349776B2 (ja) * 2002-06-04 2009-10-21 株式会社ニデック 眼内レンズの製造方法
DE102006028507A1 (de) * 2006-06-21 2007-12-27 *Acri.Tec AG Gesellschaft für ophthalmologische Produkte Ophthalmologische Zusammensetzung und ihre Verwendung
EP2225325B1 (en) * 2007-07-25 2011-06-01 Alcon, Inc. High refractive index ophthalmic device materials
DE102011112778A1 (de) * 2011-09-09 2013-03-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Die Primärwaschkraft verbessernde polymere Wirkstoffe
CN104558403B (zh) * 2013-10-28 2016-09-07 中国石油化工股份有限公司 交联渐变溶胀型聚合物微球及其制备方法
CN103655003A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种可折叠后房室固定型人工晶体及其制备方法
US12127934B2 (en) 2014-09-09 2024-10-29 Staar Surgical Company Method of Providing Modified Monovision to a Subject with a First Lens and a Second Lens
US10881504B2 (en) 2016-03-09 2021-01-05 Staar Surgical Company Ophthalmic implants with extended depth of field and enhanced distance visual acuity
CN107072779B (zh) 2014-09-09 2020-01-14 斯塔尔外科有限公司 具有扩展的景深和增强的远距视力的眼科植入物
JP6924696B2 (ja) * 2014-10-17 2021-08-25 キー メディカル テクノロジーズ インコーポレイテッド 眼適用のためのポリマーおよび方法
CN112867944A (zh) 2018-08-17 2021-05-28 斯塔尔外科有限公司 呈现折射率纳米梯度的聚合物组合物
AU2022360960A1 (en) 2021-10-04 2024-04-18 Staar Surgical Company Ophthalmic implants for correcting vision with a tunable optic, and methods of manufacture and use
DE102022125341B3 (de) * 2022-09-30 2024-01-04 Carl Zeiss Meditec Ag Ophthalmologische Zusammensetzung mit mehreren Comonomergruppen und ophthalmologische Linse

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2541930A (en) * 1946-11-16 1951-02-13 Geigy Ag J R Amides of monocarboxylic acids having acaricidal and disinfecting properties
GB855741A (en) * 1958-08-30 1960-12-07 British Nylon Spinners Ltd Improvements in or relating to polyacrylamide derivatives
CH476689A (de) * 1965-04-01 1969-08-15 Ciba Geigy Verfahren zur Herstellung neuer polymerisierbarer N-Aryl-methylcarbonsäureamide
US3716467A (en) * 1968-07-05 1973-02-13 Agency Ind Science Techn Process for the radiation insolubilization of n-(vinyl) phenylacrylamide
US4337332A (en) * 1981-04-09 1982-06-29 Minnesota Mining And Manufacturing Company Latently curable organosilicone compositions
DE4023578A1 (de) * 1990-07-25 1992-01-30 Chemie Linz Deutschland Copolymere von hydroxyethyl(meth)acrylat und n-substituierten (meth)acrylamiden
US5480950A (en) * 1992-09-28 1996-01-02 Kabi Pharmacia Ophthalmics, Inc. High refractive index hydrogels and uses thereof
US5439950A (en) * 1994-06-27 1995-08-08 Kabi Pharmacia Ophthalmics, Inc. Water miscible non-hydrolyzable cross-linkers and high refractive index hydrogels prepared therewith
DE4423303C2 (de) * 1994-07-02 2000-05-31 Woehlk Contact Linsen Gmbh Hydrophile, vernetzte Copolymere auf der Basis von N-Vinylformamid, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
DE69721750T2 (de) 2003-11-13
KR20040084954A (ko) 2004-10-06
CN1219179A (zh) 1999-06-09
US5717049A (en) 1998-02-10
EP0889916A4 (en) 2000-06-28
JP2000507298A (ja) 2000-06-13
DK0889916T3 (da) 2003-07-28
AU2040497A (en) 1997-10-17
EP0889916A1 (en) 1999-01-13
ATE239758T1 (de) 2003-05-15
WO1997035896A1 (en) 1997-10-02
DE69721750D1 (de) 2003-06-12
AU712171B2 (en) 1999-10-28
PT889916E (pt) 2003-08-29
KR100482946B1 (ko) 2005-04-15
NZ331946A (en) 2000-03-27
ES2200160T3 (es) 2004-03-01
CN1103786C (zh) 2003-03-26
CA2249991A1 (en) 1997-10-02
EP0889916B1 (en) 2003-05-07

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements