BR9709677A - Composto, complexo, e, processo para formar um composto - Google Patents

Composto, complexo, e, processo para formar um composto

Info

Publication number
BR9709677A
BR9709677A BR9709677-6A BR9709677A BR9709677A BR 9709677 A BR9709677 A BR 9709677A BR 9709677 A BR9709677 A BR 9709677A BR 9709677 A BR9709677 A BR 9709677A
Authority
BR
Brazil
Prior art keywords
compound
complex
catalysts
useful
key components
Prior art date
Application number
BR9709677-6A
Other languages
English (en)
Other versions
BR9709677B1 (pt
Inventor
Philip Pye
Kai Rossan
Ralph P Volante
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BR9709677A publication Critical patent/BR9709677A/pt
Publication of BR9709677B1 publication Critical patent/BR9709677B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5027—Polyphosphines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65525—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring
    • C07F9/65527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655381—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a seven-(or more) membered ring
    • C07F9/65539—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a seven-(or more) membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

"COMPOSTO, COMPLEXO, E, PROCESSO PARA FORMAR UM COMPOSTO". As novas bisfosfinas quirais, por exemplo, (A): são úteis como componentes chave de catalisadores para reações assimétricas, provendo, desejavelmente, elevado excesso enanciomérico (ee).
BRPI9709677-6A 1996-06-12 1997-06-10 composto derivados de bisfosfinas quirais, seus complexos com um metal e um ligante, e, seus processos de produção. BR9709677B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1959096P 1996-06-12 1996-06-12
PCT/US1997/009827 WO1997047632A1 (en) 1996-06-12 1997-06-10 Novel chiral bisphosphines

Publications (2)

Publication Number Publication Date
BR9709677A true BR9709677A (pt) 2000-05-09
BR9709677B1 BR9709677B1 (pt) 2010-05-18

Family

ID=21794005

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9709677-6A BR9709677B1 (pt) 1996-06-12 1997-06-10 composto derivados de bisfosfinas quirais, seus complexos com um metal e um ligante, e, seus processos de produção.

Country Status (18)

Country Link
US (2) US5874629A (pt)
EP (1) EP0906322B1 (pt)
CN (1) CN1082964C (pt)
AR (1) AR007555A1 (pt)
AT (1) ATE238319T1 (pt)
AU (1) AU3303897A (pt)
BR (1) BR9709677B1 (pt)
CZ (1) CZ295748B6 (pt)
DE (1) DE69721257T2 (pt)
DK (1) DK0906322T3 (pt)
EA (1) EA001377B1 (pt)
ES (1) ES2196343T3 (pt)
HU (1) HU223052B1 (pt)
PT (1) PT906322E (pt)
SK (1) SK284369B6 (pt)
TW (1) TW450971B (pt)
UA (1) UA57742C2 (pt)
WO (1) WO1997047632A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6334219B1 (en) * 1994-09-26 2001-12-25 Adc Telecommunications Inc. Channel selection for a hybrid fiber coax network
US5977364A (en) * 1998-02-02 1999-11-02 Merck & Co., Inc. Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide
DE10005794A1 (de) * 2000-02-10 2001-08-16 Basf Ag Verbindungen des Phosphors, Arsens und des Antimons
WO2001074829A1 (en) * 2000-03-30 2001-10-11 Chirotech Technology Limited Ruthenium-diphosphine complexes and their use as catalysts
US6482952B2 (en) 2000-06-20 2002-11-19 Merck & Co., Inc. Process for preparing acetonides
JP2004517901A (ja) * 2001-01-19 2004-06-17 カイロテック・テクノロジー・リミテッド 配位子およびその使用
GB0313709D0 (en) * 2003-06-13 2003-07-16 Johnson Matthey Plc Ligands
JP2006527246A (ja) * 2003-06-13 2006-11-30 ジョンソン、マッセイ、パブリック、リミテッド、カンパニー 配位子
US7449601B2 (en) * 2004-12-16 2008-11-11 E. I. Du Pont De Nemours And Company Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids
WO2006097314A1 (de) * 2005-03-17 2006-09-21 Basf Aktiengesellschaft Verfahren zur herstellung von optisch aktiven 3-phenylpropionsäurederivaten und folgeprodukte davon
EP1885688B1 (en) * 2005-05-20 2010-09-22 Dr. Reddy's Laboratories (EU) Limited Asymmetric hydrogenation for the preparation of diphenylalanine derivatives
GB0700622D0 (en) 2007-01-12 2007-02-21 Johnson Matthey Plc Process for preparing cationic rhodium complexes
GB0716714D0 (en) 2007-08-29 2007-10-10 Johnson Matthey Plc Ligands
GB0812290D0 (en) 2008-07-04 2008-08-13 Johnson Matthey Plc Process for preparing cationic rhodium complexes
GB0915946D0 (en) 2009-09-11 2009-10-28 Univ St Andrews Metal-catalysed carbonylation of unsaturated compounds
CZ303113B6 (cs) * 2010-03-16 2012-04-11 Zentiva, K.S. Zpusob prípravy sitagliptinu
GB201104522D0 (en) * 2011-03-17 2011-05-04 Johnson Matthey Plc Complexes
CN118420681A (zh) * 2024-04-28 2024-08-02 浙江工业大学 基于[2,2]对环芳烷金属(ii)配合物、电子器件、装置及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2681057B2 (ja) * 1990-10-01 1997-11-19 高砂香料工業株式会社 ２，２’―ビス（ジフェニルホスフィノ）―５，５’，６，６’，７，７’，８，８’―オクタヒドロ―１，１’―ビナフチル及びこれを配位子とする遷移金属錯体
DE4330730A1 (de) * 1993-09-10 1995-03-16 Bayer Ag Neue Bisphosphine für asymmetrische Hydrierkatalysatoren
ES2130321T3 (es) * 1993-10-08 1999-07-01 Hoffmann La Roche Compuestos de fosforo opticamente activos.
US5399771A (en) * 1994-06-01 1995-03-21 Merck & Co., Inc. Process of synthesizing binaphthyl derivatives

Also Published As

Publication number Publication date
HU223052B1 (hu) 2004-03-01
EP0906322B1 (en) 2003-04-23
ES2196343T3 (es) 2003-12-16
CN1221422A (zh) 1999-06-30
CN1082964C (zh) 2002-04-17
EA199900016A1 (ru) 1999-06-24
CZ295748B6 (cs) 2005-10-12
EA001377B1 (ru) 2001-02-26
UA57742C2 (uk) 2003-07-15
SK169198A3 (en) 1999-08-06
AR007555A1 (es) 1999-11-10
HUP9902412A2 (hu) 1999-11-29
TW450971B (en) 2001-08-21
ATE238319T1 (de) 2003-05-15
DE69721257D1 (de) 2003-05-28
DE69721257T2 (de) 2004-02-05
US5874629A (en) 1999-02-23
HUP9902412A3 (en) 2001-09-28
PT906322E (pt) 2003-08-29
DK0906322T3 (da) 2003-06-02
BR9709677B1 (pt) 2010-05-18
CZ409898A3 (cs) 1999-05-12
SK284369B6 (sk) 2005-02-04
US6043387A (en) 2000-03-28
EP0906322A1 (en) 1999-04-07
WO1997047632A1 (en) 1997-12-18
AU3303897A (en) 1998-01-07

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DE INT.CL.8: C07F 9/50, C07F 15/00, C07C 25/13, C07D 241/06

Ipc: C07F 9/50 (2007.01), C07F 15/00 (2007.01), C07C 25

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/05/2010, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved

Owner name: MERCK SHARP AND DOHME CORP. (US)

Free format text: NOME ALTERADO DE: MERCK AND CO., INC.

B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2259 DE 22/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 16A, 17A, 18A, 19A, 20A, 21A, 22A E 23A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.