BR9709905A - Derivados de heterociclilmetilamino de ciclobuteno-3,4-dionas como moduladores do canal de potássio - Google Patents

Derivados de heterociclilmetilamino de ciclobuteno-3,4-dionas como moduladores do canal de potássio

Info

Publication number
BR9709905A
BR9709905A BR9709905A BR9709905A BR9709905A BR 9709905 A BR9709905 A BR 9709905A BR 9709905 A BR9709905 A BR 9709905A BR 9709905 A BR9709905 A BR 9709905A BR 9709905 A BR9709905 A BR 9709905A
Authority
BR
Brazil
Prior art keywords
heterocyclylmethylamino
cyclobutene
diones
modulators
derivatives
Prior art date
Application number
BR9709905A
Other languages
English (en)
Inventor
David Richard Herbst
John Anthony Butera
Russel Francis Graceffa
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of BR9709905A publication Critical patent/BR9709905A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR9709905A 1996-06-17 1997-06-10 Derivados de heterociclilmetilamino de ciclobuteno-3,4-dionas como moduladores do canal de potássio BR9709905A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66458396A 1996-06-17 1996-06-17
PCT/US1997/009744 WO1997048682A1 (en) 1996-06-17 1997-06-10 Heterocyclylmethylamino derivatives of cyclobutene-3,4-diones as potassium channel modulators

Publications (1)

Publication Number Publication Date
BR9709905A true BR9709905A (pt) 1999-08-10

Family

ID=24666578

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9709905A BR9709905A (pt) 1996-06-17 1997-06-10 Derivados de heterociclilmetilamino de ciclobuteno-3,4-dionas como moduladores do canal de potássio

Country Status (13)

Country Link
EP (1) EP0906282A1 (pt)
JP (1) JP2000512655A (pt)
KR (1) KR20000016815A (pt)
CN (1) CN1227543A (pt)
AR (1) AR008238A1 (pt)
AU (1) AU727217B2 (pt)
BR (1) BR9709905A (pt)
CA (1) CA2258536A1 (pt)
IL (1) IL127261A0 (pt)
NZ (1) NZ332859A (pt)
TW (1) TW442473B (pt)
WO (1) WO1997048682A1 (pt)
ZA (1) ZA975287B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232860A1 (en) * 2000-07-18 2003-12-18 Hironori Harada Medicine comprising dicyanopyridine derivative
US6495576B2 (en) 2001-02-07 2002-12-17 Abbott Laboratories Aminal diones as potassium channel openers
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2222083A (en) * 1982-12-14 1984-06-21 Smith Kline & French Laboratories Limited Pyridine derivatives
JPS60255756A (ja) * 1984-06-01 1985-12-17 Ikeda Mohandou:Kk アミノアルキルフエノキシ誘導体
JPH0692915A (ja) * 1992-07-28 1994-04-05 Sumitomo Metal Ind Ltd 1,2−ジアミノシクロブテン−3,4−ジオン誘導体及びその用途
US5354763A (en) * 1993-11-17 1994-10-11 American Home Products Corporation Substituted N-heteroaryl and N-aryl-1,2-diaminocyclobutene-3,4-diones
US5466712A (en) * 1994-11-04 1995-11-14 American Home Products Corporation Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones
US5464867A (en) * 1994-11-16 1995-11-07 American Home Products Corporation Diaminocyclobutene-3,4-diones

Also Published As

Publication number Publication date
CA2258536A1 (en) 1997-12-24
AU727217B2 (en) 2000-12-07
CN1227543A (zh) 1999-09-01
WO1997048682A1 (en) 1997-12-24
NZ332859A (en) 2000-06-23
AR008238A1 (es) 1999-12-29
EP0906282A1 (en) 1999-04-07
ZA975287B (en) 1998-12-14
TW442473B (en) 2001-06-23
JP2000512655A (ja) 2000-09-26
IL127261A0 (en) 1999-09-22
KR20000016815A (ko) 2000-03-25
AU3301797A (en) 1998-01-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A , 6A , 7A E 8A ANUIDADES.