BR9714631A - Método para tratar terapeuticamente olhos de mamìferos e medicamento antiinfeccioso de iodo não-irritante, oftálmico - Google Patents

Método para tratar terapeuticamente olhos de mamìferos e medicamento antiinfeccioso de iodo não-irritante, oftálmico

Info

Publication number
BR9714631A
BR9714631A BR9714631-5A BR9714631A BR9714631A BR 9714631 A BR9714631 A BR 9714631A BR 9714631 A BR9714631 A BR 9714631A BR 9714631 A BR9714631 A BR 9714631A
Authority
BR
Brazil
Prior art keywords
iodine
ophthalmic
irritating
mammalian eyes
therapeutically treating
Prior art date
Application number
BR9714631-5A
Other languages
English (en)
Inventor
Jack Kessler
Original Assignee
Symbollon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbollon Corp filed Critical Symbollon Corp
Publication of BR9714631A publication Critical patent/BR9714631A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

<B>MéTODO PARA TRATAR TERAPEUTICAMENTE OLHOS DE MAMìFEROS E MEDIAMENTO ANTIINFECCIOSO DE IODO NãO-IRRITANTE, OFTáLMICO<D>. A presente invenção refere-se a um microbicida de iodo gerado enzimaticamente para a inativação de organismos patogênicos contaminantes em ou em materiais biologicos sensíveis tais como o olho humano. O agente biocida da reação enzimática é iodo molecular livre gerado em um nível mínimo de 5 ppm e compreende pelo menos 25% de espécie de iodo total presente em uma base molar.
BR9714631-5A 1997-03-24 1997-05-31 Método para tratar terapeuticamente olhos de mamìferos e medicamento antiinfeccioso de iodo não-irritante, oftálmico BR9714631A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/826,068 US5849291A (en) 1994-10-17 1997-03-24 Opthalmic non-irritating iodine medicament
PCT/US1997/009110 WO1998042313A1 (en) 1997-03-24 1997-05-31 Opthalmic non-irritating iodine medicament and method

Publications (1)

Publication Number Publication Date
BR9714631A true BR9714631A (pt) 2000-03-28

Family

ID=25245616

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9714631-5A BR9714631A (pt) 1997-03-24 1997-05-31 Método para tratar terapeuticamente olhos de mamìferos e medicamento antiinfeccioso de iodo não-irritante, oftálmico

Country Status (8)

Country Link
US (1) US5849291A (pt)
EP (1) EP0969814A1 (pt)
JP (1) JP2001526647A (pt)
CN (1) CN1248911A (pt)
AU (1) AU725930C (pt)
BR (1) BR9714631A (pt)
CA (1) CA2284696A1 (pt)
WO (1) WO1998042313A1 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482309B1 (en) 1999-10-20 2002-11-19 Oxibio, Inc. Electrolytic generation of nascent iodine as a method of treatment and for the prevention of infections associated with medical implant devices
AU2392500A (en) * 1999-12-28 2001-07-09 Symbollon Corporation Non-staining topical iodine composition
US20060078626A1 (en) * 2000-11-08 2006-04-13 Bioconcept Laboratories Opthalmic and contact lens solutions with a peroxide source and a cationic polymeric preservative
US20030118472A1 (en) * 2001-08-08 2003-06-26 Mckee Mary Mowrey Disinfecting and cleaning system for contact lenses
JP4933897B2 (ja) 2004-11-05 2012-05-16 千寿製薬株式会社 眼内移行性促進水性点眼剤
US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
US8021610B2 (en) * 2006-09-07 2011-09-20 Biolargo Life Technologies, Inc. Systems providing antimicrobial activity to an environment
US9414601B2 (en) * 2006-09-07 2016-08-16 Biolargo Life Technologies, Incorporated Material having antimicrobial activity when wet
US8226964B2 (en) * 2006-09-07 2012-07-24 Biolargo Life Technologies, Inc. Systems and methods for cleaning liquid carriers related applications data
US20080063560A1 (en) * 2006-09-07 2008-03-13 Biolargo Life Technologies, Incorporated Ground treatment for reducing microbial content
US7943158B2 (en) * 2006-09-07 2011-05-17 BioLargo Life Technologies, Inc Absorbent systems providing antimicrobial activity
US7867510B2 (en) * 2006-09-07 2011-01-11 BioLargo Life Technologies, Inc Material having antimicrobial activity when wet
US8257749B2 (en) * 2007-02-08 2012-09-04 Biolargo Life Technologies, Incorporated Systems providing at least pesticidal activity
AU2010339993A1 (en) * 2009-12-15 2012-07-26 Foresight Biotherapeutics, Inc. Non-irritating ophthalmic povidone-iodine compositions
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
EP2510944A1 (en) * 2011-04-15 2012-10-17 National University of Ireland, Galway Treatment of bacterial infections
GB201114725D0 (en) 2011-08-25 2011-10-12 Altacor Ltd Ophthalmic formulations
US9555111B2 (en) 2012-03-29 2017-01-31 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
WO2013149075A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
EP4420725A3 (en) 2012-03-29 2025-04-16 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
AU2013314303B2 (en) 2012-09-12 2018-01-18 Novaliq Gmbh Semifluorinated alkane compositions
CN113679699B (zh) 2012-09-12 2022-10-28 诺瓦利克有限责任公司 包含半氟化烷烃的混合物的组合物
EP2799068A1 (en) * 2013-05-01 2014-11-05 National University of Ireland, Galway Antimicrobial compositions and methods for their production
CN110403923B (zh) 2015-09-30 2021-09-21 诺瓦利克有限责任公司 半氟化化合物和其组合物
JP7516046B2 (ja) 2016-07-21 2024-07-16 アイ２ピュア・コーポレーション エモリエント性の局所消毒剤
CA3058097C (en) 2017-04-21 2024-01-02 Novaliq Gmbh Iodine compositions
WO2019068763A1 (en) 2017-10-04 2019-04-11 Novaliq Gmbh OPHTHALMIC COMPOSITIONS COMPRISING F6H8
CN112153970A (zh) 2018-04-27 2020-12-29 诺瓦利克有限责任公司 用于治疗青光眼的包含他氟前列素的眼用组合物
SG11202102820VA (en) 2018-10-12 2021-04-29 Novaliq Gmbh Ophthalmic composition for treatment of dry eye disease
CN110559175A (zh) * 2019-08-27 2019-12-13 陈文龙 一种结膜囊消毒溶液及其使用方法和装置
CN116367845A (zh) 2020-08-13 2023-06-30 I2普乐公司 高浓度分子碘组合物，药物制剂，制备和用途
US20230181625A1 (en) * 2021-12-14 2023-06-15 Harrow Ip, Llc Method and composition for treating infectious conjunctivitis
EP4309500B1 (en) * 2022-07-18 2025-06-04 Acies Bio d.o.o. Peroxidase based biocontrol agents
US20250332227A1 (en) * 2022-07-18 2025-10-30 Acies Bio D.O.O. Peroxidase based biocontrol agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588586A (en) * 1983-01-03 1986-05-13 Kessler Jack H Method for disinfecting a contact lens
US4996146A (en) * 1987-02-20 1991-02-26 Kessler Jack H Rapid sterilization enzymatic process with persistence
SE8702831L (sv) * 1987-07-10 1989-01-11 Ewos Ab Microbicid komposition
US5227161A (en) * 1988-09-06 1993-07-13 Symbollon Corporation Method to clean and disinfect pathogens on the epidermis by applying a composition containing peroxidase, iodide compound and surfactant
EP0447582B1 (en) * 1990-03-20 1996-06-12 Symbollon Corporation Method and composition for controlling color in a peroxide-Peroxidase disinfecting system
US5419902A (en) * 1993-07-16 1995-05-30 Symbollon Corporation Method for inactivating pathogens
US5629024A (en) * 1994-08-22 1997-05-13 Symbollon Corporation Method of forming an iodine based germicide composition
US5639481A (en) * 1994-10-17 1997-06-17 Symbollon Corporation Method for the therapeutic treatment of a mammalian eye using an admixed composition containing free molecular iodine
US5648075A (en) * 1994-10-17 1997-07-15 Symbollon Corporation Iodine based germicidal composition

Also Published As

Publication number Publication date
AU725930B2 (en) 2000-10-26
US5849291A (en) 1998-12-15
AU725930C (en) 2001-09-06
CA2284696A1 (en) 1998-10-01
WO1998042313A1 (en) 1998-10-01
AU3288697A (en) 1998-10-20
EP0969814A1 (en) 2000-01-12
JP2001526647A (ja) 2001-12-18
CN1248911A (zh) 2000-03-29

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1836 DE 14/03/2006.