BR9809103A - Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos - Google Patents

Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos

Info

Publication number
BR9809103A
BR9809103A BR9809103-4A BR9809103A BR9809103A BR 9809103 A BR9809103 A BR 9809103A BR 9809103 A BR9809103 A BR 9809103A BR 9809103 A BR9809103 A BR 9809103A
Authority
BR
Brazil
Prior art keywords
peptides
proteins
nucleic acids
acids
administration
Prior art date
Application number
BR9809103-4A
Other languages
English (en)
Inventor
Wolfgang Roedel
Markus Mattern
Gerhard Winter
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of BR9809103A publication Critical patent/BR9809103A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: <B>"FORMA FARMACêUTICA ESTáVEL DE ADMINISTRAçãO PARA PEPTìDEOS, PROTEìNAS E áCIDOS NUCLéICOS''<D>. A invenção refere-se a preparações liofilizadas estáveis em estocagem de biomoléculas em que as biomoléculas são selecionadas do grupo que compreende proteínas, peptídeos, ácido nucléicos e carboidratos e adicionalmente contêm um ou vários D ou L-aminoácidos em adição a um ou vários ácidos aminodicarboxílicos, ácidos hidroxicarboxílicos ou ácidos dicarboxílicos ou sais fisiologicamente compatíveis dos mesmos. As substâncias auxiliares estão presentes no liofilizado em uma forma completamente ou parcialmente amorfa.
BR9809103-4A 1997-04-18 1998-04-11 Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos BR9809103A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19716154A DE19716154A1 (de) 1997-04-18 1997-04-18 Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren
PCT/EP1998/002131 WO1998047490A1 (de) 1997-04-18 1998-04-11 Stabile pharmazeutische darreichungsform für peptide, proteine und nukleinsäuren

Publications (1)

Publication Number Publication Date
BR9809103A true BR9809103A (pt) 2000-08-01

Family

ID=7826847

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809103-4A BR9809103A (pt) 1997-04-18 1998-04-11 Forma farmacêutica estável de administração para peptìdeos, proteìnas e ácidos nucléicos

Country Status (10)

Country Link
EP (1) EP0975335A1 (pt)
JP (1) JP2001524090A (pt)
KR (1) KR20010006562A (pt)
CN (1) CN1261271A (pt)
AU (1) AU744777B2 (pt)
BR (1) BR9809103A (pt)
CA (1) CA2288649A1 (pt)
DE (1) DE19716154A1 (pt)
TR (1) TR199902575T2 (pt)
WO (1) WO1998047490A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1555033A3 (en) * 1998-03-13 2005-08-17 Wyeth Polynucleotide composition, method of preparation, and use thereof
WO1999045966A1 (en) * 1998-03-13 1999-09-16 American Home Products Corporation Polynucleotide composition, method of preparation, and use thereof
US7276359B1 (en) 1998-03-13 2007-10-02 Wyeth Polynucleotide composition, method of preparation, and use thereof
DE19840531C2 (de) * 1998-08-28 2003-05-15 Roboscreen Ges Fuer Molekulare Mit Nukleinsäuren beschichtete Reaktionsräume, Verfahren zu ihrer Herstellung und ihre Verwendung
CA2375779A1 (en) * 1999-05-31 2000-12-07 Mitsubishi Chemical Corporation Lyophilized hgf preparation
DE10149030A1 (de) * 2001-10-05 2003-04-10 Viscum Ag Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin
WO2005011740A1 (en) * 2003-08-05 2005-02-10 Fuji Photo Film B.V. Use of recombinant or synthetic gelatin-like proteins as stabiliser in lyophilized pharmaceutical compositions
EP2168975A3 (en) 2004-05-24 2012-01-11 Genvault Corporation Method of stably storing biomolecules in recoverable form
GB0517688D0 (en) * 2005-08-31 2005-10-05 Cambridge Biostability Ltd Improvements in the stabilisation of biological materials
US20090163421A1 (en) * 2007-12-19 2009-06-25 Ekr Therapeutics, Inc. Room Temperature Stable, Lyophilized Natriuretic Peptide Formulations
JP2012501681A (ja) 2008-09-12 2012-01-26 ジェンボールト コーポレイション 生体分子の貯蔵および安定化のためのマトリックスおよび媒体
KR102369835B1 (ko) 2014-12-08 2022-03-04 삼성디스플레이 주식회사 표시 장치 및 표시 방법
JP2016109914A (ja) 2014-12-08 2016-06-20 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． 表示装置、表示方法、及びプログラム
JP2016109911A (ja) 2014-12-08 2016-06-20 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． 表示装置、表示方法、及びプログラム

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63115822A (ja) * 1986-11-04 1988-05-20 Teijin Ltd 生理活性ポリペプチド類の経鼻投与用粉末状組成物
DE3729863A1 (de) * 1987-09-05 1989-03-16 Boehringer Mannheim Gmbh Stabilisierte erythropoietin-lyophilisate
DE4126983A1 (de) * 1991-08-15 1993-02-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke
DE4126984A1 (de) * 1991-08-15 1993-02-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von humanprotein-enthaltenden, gut vertraeglichen arzneimitteln fuer infusions- oder injektionszwecke
DE19538687A1 (de) * 1995-10-17 1997-04-24 Boehringer Mannheim Gmbh Stabile pharmazeutische Darreichungsformen enthaltend Parathormon

Also Published As

Publication number Publication date
KR20010006562A (ko) 2001-01-26
DE19716154A1 (de) 1998-10-22
CN1261271A (zh) 2000-07-26
JP2001524090A (ja) 2001-11-27
WO1998047490A1 (de) 1998-10-29
AU7758598A (en) 1998-11-13
EP0975335A1 (de) 2000-02-02
AU744777B2 (en) 2002-03-07
CA2288649A1 (en) 1998-10-29
TR199902575T2 (xx) 2000-02-21

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Legal Events

Date Code Title Description
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1891 DE 03/04/2007.