BR9812321A - Modulação de respostas imunológicas - Google Patents
Modulação de respostas imunológicasInfo
- Publication number
- BR9812321A BR9812321A BR9812321-1A BR9812321A BR9812321A BR 9812321 A BR9812321 A BR 9812321A BR 9812321 A BR9812321 A BR 9812321A BR 9812321 A BR9812321 A BR 9812321A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- immune
- modulation
- alkenyl
- animal
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 229960001438 immunostimulant agent Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 230000004044 response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: <B>"MODULAçãO DE RESPOSTAS IMUNOLóGICAS"<D>. Um processo de afetar ou de modular para estímulo ou supressão do produto da célula imunológica de acordo com uma resposta inunológica a um estimulante imunológico externo ou endógeno em um animal que compreende as etapas de administração a tal animal de uma quantidade eficaz moduladora imune não-tóxica de um composto selecionado do grupo que consiste em compostos de fórmula geral (I) R~ 1~-CO-NR~ 2~R~ 3~ em que R~ 1~ é selecionado do grupo que consiste em H e grupos alquila inferior (isto é, C~ 1~ a C~ 3~) e C~ 2~ a C~ 3~ alquenila; R~ 2~ e R~ 3~ são os mesmos ou diferentes e cada um é selecionado do grupo que consiste em H, grupos alquila inferior (isto é, C~ 1~ a C~ 3~) e C~ 2~ a C~ 3~ alquenila que podem opcionalmente ser halogenados ou hidroxilados ou que podem em combinação um com o outro formar um grupo -(CH~ 2~)<B>~ n~<D>- em que n é qualquer número de 2 a 5 ou o grupo -(CH~ 2~)~ 2~-O-(CH~ 2~)~ 2~ e metabólitos e pró-drogas dos mesmos. O processo é útil no tratamento de uma variedade de enfermidades associadas a respostas imunológicas inapropriadas e a invenção fornece o uso de compostos de Fórmula (I) na fabricação de medicamentos para uso no tratamento de tais enfermidades e para preparações farmacêuticas que contêm os mesmos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA978319 | 1997-09-16 | ||
| PCT/US1998/019126 WO1999013885A1 (en) | 1997-09-16 | 1998-09-16 | Modulation of immune responses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9812321A true BR9812321A (pt) | 2000-09-05 |
Family
ID=25586589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9812321-1A BR9812321A (pt) | 1997-09-16 | 1998-09-16 | Modulação de respostas imunológicas |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1019063A4 (pt) |
| JP (1) | JP2001516721A (pt) |
| CN (1) | CN1279612A (pt) |
| AU (1) | AU737867B2 (pt) |
| BR (1) | BR9812321A (pt) |
| CA (1) | CA2304119A1 (pt) |
| IL (1) | IL135091A0 (pt) |
| NO (1) | NO20001341L (pt) |
| NZ (1) | NZ503418A (pt) |
| WO (1) | WO1999013885A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2324631A1 (en) * | 2000-10-26 | 2002-04-26 | Virodene Pharmaceutical Holdings (Proprietary) Limited | A substance or composition for the treatment of cancer |
| US20070212402A1 (en) * | 2003-12-05 | 2007-09-13 | Rooven Qainton V | Patch |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5814659A (en) * | 1996-04-23 | 1998-09-29 | Dtr Dermal Therapy (Barbados) Inc. | Topical analgesic composition |
-
1998
- 1998-09-16 JP JP2000511505A patent/JP2001516721A/ja active Pending
- 1998-09-16 CN CN98810397A patent/CN1279612A/zh active Pending
- 1998-09-16 EP EP98946998A patent/EP1019063A4/en not_active Withdrawn
- 1998-09-16 WO PCT/US1998/019126 patent/WO1999013885A1/en not_active Ceased
- 1998-09-16 IL IL13509198A patent/IL135091A0/xx unknown
- 1998-09-16 AU AU93890/98A patent/AU737867B2/en not_active Ceased
- 1998-09-16 CA CA002304119A patent/CA2304119A1/en not_active Abandoned
- 1998-09-16 NZ NZ503418A patent/NZ503418A/xx not_active IP Right Cessation
- 1998-09-16 BR BR9812321-1A patent/BR9812321A/pt not_active IP Right Cessation
-
2000
- 2000-03-15 NO NO20001341A patent/NO20001341L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ503418A (en) | 2001-02-23 |
| AU9389098A (en) | 1999-04-05 |
| IL135091A0 (en) | 2001-05-20 |
| JP2001516721A (ja) | 2001-10-02 |
| NO20001341L (no) | 2000-05-16 |
| CA2304119A1 (en) | 1999-03-25 |
| CN1279612A (zh) | 2001-01-10 |
| WO1999013885A1 (en) | 1999-03-25 |
| EP1019063A1 (en) | 2000-07-19 |
| NO20001341D0 (no) | 2000-03-15 |
| EP1019063A4 (en) | 2003-09-03 |
| AU737867B2 (en) | 2001-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7O, 8O E 9O ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1909 DE 07/08/2007. |