BR9816014A - Transporte eletricamente controlado de penetrantes carregados através de barreiras - Google Patents

Transporte eletricamente controlado de penetrantes carregados através de barreiras

Info

Publication number
BR9816014A
BR9816014A BR9816014-1A BR9816014A BR9816014A BR 9816014 A BR9816014 A BR 9816014A BR 9816014 A BR9816014 A BR 9816014A BR 9816014 A BR9816014 A BR 9816014A
Authority
BR
Brazil
Prior art keywords
penetrants
pores
agents
transport
barriers
Prior art date
Application number
BR9816014-1A
Other languages
English (en)
Inventor
Gregor Cevc
Original Assignee
Idea Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idea Ag filed Critical Idea Ag
Publication of BR9816014A publication Critical patent/BR9816014A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Battery Electrode And Active Subsutance (AREA)

Abstract

Patente de Invenção:<B>"TRANSOPORTE ELETRICAMENTE CONTROLADO DE PENETRANTES CARREGADOS ATRAVéS DE BARREIRAS"<D>. Constitui um objetivo da invenção fornecer uma preparação compreendendo penetrantes formados por moléculas individuais ou por arranjos de moléculas, os referidos penetrantes sendo capazes de penetrar nos poros de uma barreira mesmo quando o diâmetro médio dos referidos poros da barreira é menor que o diâmetro médio dos referios penetrantes, desde que os penetrantes sejam adaptáveis aos poros, e os referidos penetrantes sendo capazes de transportar agentes através dos referidos poros, ou permitir a permeação de agentes através dos referidos poros depois de os penetrantes terem entrado nos referidos poros; o diâmetro médio e a adaptabilidade dos referidos penetrantes sendo selecioandos, e os referidos penetrantes e/ou os referidos agentes sendo dotados de cargas elétricas suficientes para permitir e/ou controlar o transporte dos agentes através dos referidos poros pelos referidos penetrantes, ou a permeação de agentes através dos referidos poros depois da entrada dos penetrantes nos referidos poros, sob a influência de uma força eletromotriz adequada, a referida seleção ao mesmo tempo mantendo estabilidade suficiente dos penetrantes. Constitui um outro objetivo da invenção fornecer um método para efetuar o transporte eletricamente induzido dos referidos penetrantes e moléculas associadas através dos poros em uma barreira.
BR9816014-1A 1998-09-01 1998-09-01 Transporte eletricamente controlado de penetrantes carregados através de barreiras BR9816014A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1998/005539 WO2000012060A1 (en) 1998-09-01 1998-09-01 Electrically controlled transport of charged penetrants across barriers

Publications (1)

Publication Number Publication Date
BR9816014A true BR9816014A (pt) 2001-05-08

Family

ID=8167046

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9816014-1A BR9816014A (pt) 1998-09-01 1998-09-01 Transporte eletricamente controlado de penetrantes carregados através de barreiras

Country Status (9)

Country Link
EP (1) EP1107729A1 (pt)
JP (1) JP2002523442A (pt)
KR (1) KR20010106462A (pt)
CN (1) CN1322129A (pt)
AU (1) AU9740498A (pt)
BR (1) BR9816014A (pt)
CA (1) CA2345355A1 (pt)
MX (1) MXPA01002149A (pt)
WO (1) WO2000012060A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040105881A1 (en) 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
CN101374860A (zh) * 2005-12-23 2009-02-25 技术转让合伙人公司 用作神经递质分泌抑制剂和肌肉松弛诱导物的合成肽
CN105434353A (zh) * 2009-06-03 2016-03-30 斯昆申技术控股有限责任公司 用于治疗深部组织疼痛的制剂
GB2486371A (en) 2009-08-21 2012-06-13 Targeted Delivery Technologies Ltd Vesicular formulations
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
ES2895910T3 (es) 2015-06-30 2022-02-23 Sequessome Tech Holdings Limited Composiciones multifásicas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6072830A (ja) * 1983-09-29 1985-04-24 Kao Corp ベシクル用組成物
WO1992003122A1 (de) * 1990-08-24 1992-03-05 Gregor Cevc Präparat zur wirkstoffapplikation in kleinsttröpfchenform
AU6764794A (en) * 1993-01-27 1994-08-29 Affymax Technologies N.V. Compositions and methods for transdermal drug delivery

Also Published As

Publication number Publication date
JP2002523442A (ja) 2002-07-30
WO2000012060A8 (en) 2000-06-22
CN1322129A (zh) 2001-11-14
MXPA01002149A (es) 2003-03-27
WO2000012060A1 (en) 2000-03-09
AU9740498A (en) 2000-03-21
KR20010106462A (ko) 2001-11-29
CA2345355A1 (en) 2000-03-09
EP1107729A1 (en) 2001-06-20

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5,6,7 E 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1910 DE 14/08/2007.