BR9902019A - Moléculas de polinucleotìdios que codificam proteìnas de neospora. - Google Patents

Moléculas de polinucleotìdios que codificam proteìnas de neospora.

Info

Publication number
BR9902019A
BR9902019A BR9902019-0A BR9902019A BR9902019A BR 9902019 A BR9902019 A BR 9902019A BR 9902019 A BR9902019 A BR 9902019A BR 9902019 A BR9902019 A BR 9902019A
Authority
BR
Brazil
Prior art keywords
polynucleotide molecules
neospora
present
proteins
encode
Prior art date
Application number
BR9902019-0A
Other languages
English (en)
Inventor
David Alan Brake
Rebeca Anne Madura
Becky Ann Durtschi
Balakrishnan Rajendra Krishnan
Susan Christine Yoder
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9902019A publication Critical patent/BR9902019A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

patente de Invenção: <B>"MOLéCULAS DE POLINUCLEOTìDIOS QUE CODIFICAM PROTEìNAS DE NEOSPORA"<D>. A presente invenção provê moléculas polinucleotídicas isoladas compreendendo seq³ências de nucleotídeos que codificam proteínas GRA1, GRA2, SAG1, MIC1, e MAG1 de Neospora caninum, bem como vetores recombinantes, células hospedeiras transformadas e proteínas expressas de forma recombinante. A presente invenção provê ainda uma molécula polinucleotídica que compreende a seq³ência de nucleotídeos do promotor bidirecional GRA1/MAG1 de N. caninum. A presente invenção provê ainda construções genéticas baseadas nas moléculas polinucleotídicas da presente invenção que são úteis na preparação de células de estirpes modificadas de Neospora para utilização em vacinas contra a neosporose.
BR9902019-0A 1998-03-26 1999-03-26 Moléculas de polinucleotìdios que codificam proteìnas de neospora. BR9902019A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7938998P 1998-03-26 1998-03-26
US11228298P 1998-12-15 1998-12-15

Publications (1)

Publication Number Publication Date
BR9902019A true BR9902019A (pt) 2000-05-02

Family

ID=26761953

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9902019-0A BR9902019A (pt) 1998-03-26 1999-03-26 Moléculas de polinucleotìdios que codificam proteìnas de neospora.

Country Status (9)

Country Link
US (2) US6600027B1 (pt)
EP (1) EP0953641A3 (pt)
JP (5) JPH11332583A (pt)
CN (1) CN1232087A (pt)
AR (1) AR015252A1 (pt)
AU (1) AU759103B2 (pt)
BR (1) BR9902019A (pt)
CA (1) CA2264260A1 (pt)
NZ (1) NZ334839A (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
ES2263317B2 (es) * 2003-12-04 2007-10-01 Universidad Complutense De Madrid Uso del gen ncsag4 para el diagnostico y prevencion de la neosporosis, y como marcador para el analisis de la patogenia.
KR20110132416A (ko) * 2004-04-05 2011-12-07 화이자 프로덕츠 인코포레이티드 미세유체화된 수중유 유화액 및 백신 조성물
ES2319242B1 (es) 2005-12-23 2009-12-01 Laboratorios Hipra, S.A. Aislado avirulento de neospora canimum y sus usos.
ES2326770B1 (es) 2007-07-13 2010-07-26 Universidad Complutense De Madrid Uso de un nuevo aislado de neospora caninum para el desarrollo de pruebas de diagnostico y para la fabricacion de productos para el tratamiento y prevencion de la infenccion causada por neospora.
ES2569907T3 (es) * 2008-06-27 2016-05-13 Zoetis Services Llc Composiciones adyuvantes novedosas
CN101831495B (zh) * 2010-04-30 2013-06-19 新疆出入境检验检疫局检验检疫技术中心 一种牛新孢子虫病的检测方法及应用
CN104411338A (zh) * 2012-04-02 2015-03-11 现代治疗公司 用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
FR2994193B1 (fr) * 2012-08-02 2016-05-20 Vitamfero Souches mutantes de neospora et leurs utilisations
CN102838984B (zh) * 2012-09-12 2014-06-04 浙江理工大学 一种胰凝乳蛋白酶保护金纳米团簇荧光材料的制备方法
CN107325166A (zh) * 2017-05-15 2017-11-07 华中农业大学 柔嫩艾美耳球虫表面抗原基因sag6所编码的重组蛋白及其应用
CN110407944B (zh) * 2018-04-29 2023-04-21 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 隐孢子虫多表位基因片段cpmcef及其融合蛋白和应用
CN110183527B (zh) * 2019-05-21 2021-03-12 中国农业大学 一种新孢子虫NcMIC26抗原及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940598A1 (de) * 1989-12-08 1991-06-13 Behringwerke Ag Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung
FR2625099B1 (fr) * 1987-12-24 1991-06-14 Transgene Sa Proteines et leur procede de preparation, sequences d'adn, anticorps et leur application, poxvirus, cellules transformees ou infectees et compositions pharmaceutiques utiles dans la prevention de la toxoplasmose
US5665542A (en) * 1989-11-03 1997-09-09 Research Institute Of Palo Alto Medical Foundation Toxoplasma gondii P28 gene and methods for its use
FR2692282B1 (fr) * 1992-06-15 1995-07-13 Pasteur Institut Clonage du gene codant pour la proteine gp28.5 de t. gondii; fragments peptidiques issus de ladite proteine et leurs applications.
US5976553A (en) 1993-11-04 1999-11-02 The Board Of Trustees Of The Leland Stanford Junior University Transfection and genetic manipulations in obligate intracellular parasites
US5643718A (en) 1993-11-04 1997-07-01 The Board Of Trustees Of The Leland Stanford Junior University Transfection and genetic manipulations in obligate intracellular parasites
FR2714074B1 (fr) * 1993-12-20 1996-03-01 Pasteur Institut Promoteurs des gènes GRA1, GRA2, GRA5 et GRA6 de toxoplasma gondii et vecteurs d'expression comprenant lesdits promoteurs.
US5707617A (en) 1994-03-21 1998-01-13 The Regents Of The University Of California Bovine neospora isolates
US5889166A (en) 1996-05-10 1999-03-30 The Regents Of The University Of California Recombinant neospora antigens and their uses
AU7677896A (en) 1995-11-09 1997-05-29 Trustees Of Dartmouth College A vaccine against toxoplasma gondii
US6476192B1 (en) * 1996-04-15 2002-11-05 Nicola C. Lally Recombinant antigens useful for the serodiagnosis of neosporosis
AUPO188396A0 (en) 1996-08-26 1996-09-19 Insearch Limited Detection of protozoan parasites
PT841392E (pt) * 1996-11-12 2004-11-30 Univ Auburn Vacina viva atenuada de neospora
AUPO690397A0 (en) 1997-05-20 1997-06-12 Insearch Limited Large subunit ribosomal dna of neospora species
BR9803232A (pt) * 1997-08-26 2000-01-11 Pfizer Prod Inc Vaicna de neospora.
BR9812976A (pt) 1997-10-20 2000-08-08 Bayer Ag Vacina de neospora
US6071737A (en) 1998-03-16 2000-06-06 The Regents Of The University Of California Equine Neospora isolate and its uses
EP0953641A3 (en) * 1998-03-26 2002-03-13 Pfizer Products Inc. Polynucleotide molecules encoding neospora proteins
AUPP371798A0 (en) 1998-05-26 1998-06-18 Insearch Limited Parasite antigens
US20040131633A1 (en) * 1999-04-21 2004-07-08 University Of Technology, Sydney Parasite antigens

Also Published As

Publication number Publication date
AU2243799A (en) 1999-10-07
EP0953641A3 (en) 2002-03-13
JP2005245456A (ja) 2005-09-15
JP2005253467A (ja) 2005-09-22
JPH11332583A (ja) 1999-12-07
CN1232087A (zh) 1999-10-20
CA2264260A1 (en) 1999-09-26
NZ334839A (en) 2000-08-25
US20030180785A1 (en) 2003-09-25
EP0953641A2 (en) 1999-11-03
US6600027B1 (en) 2003-07-29
JP2005211082A (ja) 2005-08-11
JP2005211081A (ja) 2005-08-11
AR015252A1 (es) 2001-04-18
AU759103B2 (en) 2003-04-03

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1994 DE 24/03/2009