BR9909422A - Método para tratamento de hipertrofia cardìaca, método para preparação de composição farmacêutica para o tratamento de hipertrofia cardìaca e seu produto farmacêutico - Google Patents
Método para tratamento de hipertrofia cardìaca, método para preparação de composição farmacêutica para o tratamento de hipertrofia cardìaca e seu produto farmacêuticoInfo
- Publication number
- BR9909422A BR9909422A BR9909422-3A BR9909422A BR9909422A BR 9909422 A BR9909422 A BR 9909422A BR 9909422 A BR9909422 A BR 9909422A BR 9909422 A BR9909422 A BR 9909422A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- cardiac hypertrophy
- pharmaceutical composition
- hypertrophy
- heart
- Prior art date
Links
- 208000006029 Cardiomegaly Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 206010007572 Cardiac hypertrophy Diseases 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 229940127557 pharmaceutical product Drugs 0.000 title abstract 2
- 208000020446 Cardiac disease Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 102000008070 Interferon-gamma Human genes 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 206010067171 Regurgitation Diseases 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 206010020871 hypertrophic cardiomyopathy Diseases 0.000 abstract 1
- 229960003130 interferon gamma Drugs 0.000 abstract 1
- 208000010125 myocardial infarction Diseases 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Abstract
MéTODO PARA TRATAMENTO DE HIPERTROFIA CARDìACA, MéTODO PARA PREPARAçãO DE COMPOSIçãO FARMACêUTICA PARA O TRATAMENTO DE HIPERTROFIA CARDìACA E SEU PRODUTO FARMACêUTICO" A invenção se refere ao tratamento da hipertrofia cardíaca por interferon-gama (IFN-<sym>). A hipertrofia cardíaca pode resultar de uma variedade de condições patológicas distintas, incluindo o infarto do miocárdio, a hipertensão, a cardiomiopatia hipertrófica e a regurgitação valvular. O tratamento se estende a todos os estágios do progresso da hipertrofia cardíaca, com ou sem danos estruturais do músculo do coração, independentemente do distúrbio cardíaco subjacente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8044898P | 1998-04-02 | 1998-04-02 | |
| PCT/US1999/006032 WO1999051260A2 (en) | 1998-04-02 | 1999-03-19 | Treatment of cardiac hypertrophy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9909422A true BR9909422A (pt) | 2001-09-11 |
Family
ID=22157456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9909422-3A BR9909422A (pt) | 1998-04-02 | 1999-03-19 | Método para tratamento de hipertrofia cardìaca, método para preparação de composição farmacêutica para o tratamento de hipertrofia cardìaca e seu produto farmacêutico |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6187304B1 (pt) |
| EP (2) | EP1702623B1 (pt) |
| JP (2) | JP5030329B2 (pt) |
| CN (1) | CN1201814C (pt) |
| AR (1) | AR018174A1 (pt) |
| AT (2) | ATE410181T1 (pt) |
| AU (1) | AU757910B2 (pt) |
| BR (1) | BR9909422A (pt) |
| CA (1) | CA2325442C (pt) |
| DE (2) | DE69932235T2 (pt) |
| DK (2) | DK1702623T3 (pt) |
| ES (2) | ES2267258T3 (pt) |
| IL (1) | IL138812A0 (pt) |
| NZ (1) | NZ506854A (pt) |
| TW (1) | TWI243682B (pt) |
| WO (1) | WO1999051260A2 (pt) |
| ZA (1) | ZA200004854B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020192659A1 (en) * | 1997-09-17 | 2002-12-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| ES2267258T3 (es) * | 1998-04-02 | 2007-03-01 | Genentech, Inc. | Tratamiento de hipertrofia cardiaca. |
| PT1196186E (pt) * | 1999-07-12 | 2008-02-14 | Genentech Inc | Promoção ou inibição da angiogénese e da cardiovascularização com homólogos de ligandos/receptores do factor de necrose tumoral. |
| US7838225B2 (en) * | 1999-10-29 | 2010-11-23 | Hologic, Inc. | Methods for detection of a target nucleic acid by forming a cleavage structure using a reverse transcriptase |
| US7625584B2 (en) * | 2000-11-30 | 2009-12-01 | The Research Foundation Of State University Of New York | Method of complexing a protein by the use of a dispersed system and proteins thereof |
| US8110218B2 (en) * | 2000-11-30 | 2012-02-07 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein-lipid complexes |
| AU2002310922A1 (en) * | 2001-05-04 | 2002-11-18 | Institute Of Molecular And Cell Biology | Interferons in the treatment of ischemia |
| IL161630A0 (en) * | 2001-11-06 | 2004-09-27 | Applied Research Systems | Methods of treating endometreosis |
| EP3192528A1 (en) * | 2002-02-14 | 2017-07-19 | Chugai Seiyaku Kabushiki Kaisha | Formulation of anti-il6r antibody-containing solutions comprising a sugar as a stabilizer |
| AU2003257588A1 (en) * | 2002-08-29 | 2004-03-19 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDINS |
| AU2003280812A1 (en) * | 2002-11-18 | 2004-06-15 | Santen Pharmaceutical Co., Ltd. | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER |
| EP1522857A1 (en) * | 2003-10-09 | 2005-04-13 | Universiteit Maastricht | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
| EP2294183B1 (en) * | 2008-06-18 | 2015-12-16 | The Texas A&M University System | Mesenchymal stem cells, compositions, and methods for treatment of cardiac tissue damage |
| USD647411S1 (en) | 2011-01-12 | 2011-10-25 | Rain Bird Corporation | Water timer |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5582824A (en) | 1981-10-19 | 1996-12-10 | Genentech, Inc. | Recombinant DES-CYS-TYR-CYS human immune interferon |
| AU561343B2 (en) | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| US5096705A (en) | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
| US4929544A (en) | 1982-04-23 | 1990-05-29 | Sri International | Reagents, methods, and test kit for diagnosing/monitoring cancer in humans |
| US4855238A (en) | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
| US4944941A (en) | 1987-08-07 | 1990-07-31 | Genentech, Inc. | Methods and compositions for the treatment of lung conditions |
| IL88233A (en) * | 1987-11-03 | 1993-08-18 | Genentech Inc | Gamma interferon formulation |
| US5151265A (en) | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
| SE462364B (sv) | 1988-09-30 | 1990-06-18 | Goeran Hansson | Anvaendning av gamma-interferon foer beredning av ett preparat foer behandling av vaskulaer stenos |
| ATE121945T1 (de) | 1989-12-01 | 1995-05-15 | Childrens Medical Center | Verwendung von gamma-interferon zur herstellung eines medikaments für die behandlung von steroid- abhängigem asthma. |
| US6207641B1 (en) * | 1995-03-10 | 2001-03-27 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pharmaceutical composition containing IFN-γ inducing polypeptide or factor for treating and/or preventing IFN-γ susceptive diseases |
| US5573762A (en) | 1995-04-24 | 1996-11-12 | Genentech, Inc. | Use of leukemia inhibitory factor specific antibodies and endothelin antagonists for treatment of cardiac hypertrophy |
| EP0790062B1 (en) * | 1995-08-30 | 2006-05-10 | Toray Industries, Inc. | Method of testing for myocarditis and cariomyopathy |
| ES2267258T3 (es) * | 1998-04-02 | 2007-03-01 | Genentech, Inc. | Tratamiento de hipertrofia cardiaca. |
-
1999
- 1999-03-19 ES ES99912711T patent/ES2267258T3/es not_active Expired - Lifetime
- 1999-03-19 IL IL13881299A patent/IL138812A0/xx not_active IP Right Cessation
- 1999-03-19 NZ NZ506854A patent/NZ506854A/en not_active IP Right Cessation
- 1999-03-19 EP EP06013719A patent/EP1702623B1/en not_active Expired - Lifetime
- 1999-03-19 DK DK06013719T patent/DK1702623T3/da active
- 1999-03-19 US US09/273,099 patent/US6187304B1/en not_active Expired - Lifetime
- 1999-03-19 DE DE69932235T patent/DE69932235T2/de not_active Expired - Lifetime
- 1999-03-19 AT AT06013719T patent/ATE410181T1/de active
- 1999-03-19 JP JP2000542031A patent/JP5030329B2/ja not_active Expired - Fee Related
- 1999-03-19 DK DK99912711T patent/DK1067958T3/da active
- 1999-03-19 CA CA2325442A patent/CA2325442C/en not_active Expired - Fee Related
- 1999-03-19 ES ES06013719T patent/ES2314786T3/es not_active Expired - Lifetime
- 1999-03-19 AT AT99912711T patent/ATE332144T1/de active
- 1999-03-19 DE DE69939723T patent/DE69939723D1/de not_active Expired - Lifetime
- 1999-03-19 AU AU31024/99A patent/AU757910B2/en not_active Ceased
- 1999-03-19 WO PCT/US1999/006032 patent/WO1999051260A2/en not_active Ceased
- 1999-03-19 BR BR9909422-3A patent/BR9909422A/pt not_active IP Right Cessation
- 1999-03-19 EP EP99912711A patent/EP1067958B1/en not_active Expired - Lifetime
- 1999-03-19 CN CNB99804881XA patent/CN1201814C/zh not_active Expired - Fee Related
- 1999-03-31 AR ARP990101482A patent/AR018174A1/es unknown
- 1999-08-10 TW TW088105269A patent/TWI243682B/zh not_active IP Right Cessation
-
2000
- 2000-09-13 ZA ZA200004854A patent/ZA200004854B/xx unknown
- 2000-11-16 US US09/715,739 patent/US6989364B1/en not_active Expired - Fee Related
-
2009
- 2009-08-04 JP JP2009181954A patent/JP2009256375A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1067958A2 (en) | 2001-01-17 |
| ES2267258T3 (es) | 2007-03-01 |
| IL138812A0 (en) | 2001-10-31 |
| US6187304B1 (en) | 2001-02-13 |
| JP2009256375A (ja) | 2009-11-05 |
| AU757910B2 (en) | 2003-03-13 |
| EP1702623A3 (en) | 2007-01-10 |
| AR018174A1 (es) | 2001-10-31 |
| EP1067958B1 (en) | 2006-07-05 |
| HK1036019A1 (en) | 2001-12-21 |
| CN1300221A (zh) | 2001-06-20 |
| ES2314786T3 (es) | 2009-03-16 |
| CN1201814C (zh) | 2005-05-18 |
| DK1067958T3 (da) | 2006-11-06 |
| HK1099197A1 (en) | 2007-08-10 |
| CA2325442A1 (en) | 1999-10-14 |
| NZ506854A (en) | 2003-07-25 |
| US6989364B1 (en) | 2006-01-24 |
| ATE410181T1 (de) | 2008-10-15 |
| WO1999051260A2 (en) | 1999-10-14 |
| DK1702623T3 (da) | 2009-01-19 |
| JP5030329B2 (ja) | 2012-09-19 |
| DE69939723D1 (de) | 2008-11-20 |
| DE69932235T2 (de) | 2007-06-14 |
| DE69932235D1 (de) | 2006-08-17 |
| ATE332144T1 (de) | 2006-07-15 |
| TWI243682B (en) | 2005-11-21 |
| EP1702623B1 (en) | 2008-10-08 |
| CA2325442C (en) | 2011-10-11 |
| ZA200004854B (en) | 2001-09-26 |
| EP1702623A2 (en) | 2006-09-20 |
| AU3102499A (en) | 1999-10-25 |
| JP2002510645A (ja) | 2002-04-09 |
| WO1999051260A3 (en) | 1999-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 37, 8O, 13 DA LPI 9279/06 |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 16A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |