BR9910907A - Compostos cìclicos de boroprolina - Google Patents

Compostos cìclicos de boroprolina

Info

Publication number
BR9910907A
BR9910907A BR9910907-7A BR9910907A BR9910907A BR 9910907 A BR9910907 A BR 9910907A BR 9910907 A BR9910907 A BR 9910907A BR 9910907 A BR9910907 A BR 9910907A
Authority
BR
Brazil
Prior art keywords
cyclic
boroproline
compounds
cyclic compounds
cells
Prior art date
Application number
BR9910907-7A
Other languages
English (en)
Inventor
Barbara P Wallner
Original Assignee
Point Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Point Therapeutics Inc filed Critical Point Therapeutics Inc
Publication of BR9910907A publication Critical patent/BR9910907A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/04—Esters of boric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"COMPOSTOS CìCLICOS DE BOROPROLINA". São proporcionadas preparações substancialmente puras de compostos cíclicos de boroProlina que se ligam, em forma cíclica ou linear, à CD26. São também proporcionados métodos para o uso dos compostos cíclicos para estimular a ativação e/ou proliferação das imuno-células para conseguir os níveis normais pré-selecionados in vivo destas células. é também proporcionada, a comprovação da biodisponibilidade e atividade de um composto cíclico preferido, o ácido valino-prolinoborónico (ValboroPro).
BR9910907-7A 1998-06-05 1999-05-14 Compostos cìclicos de boroprolina BR9910907A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8854098P 1998-06-05 1998-06-05
PCT/US1999/010777 WO1999062914A1 (en) 1998-06-05 1999-05-14 Cyclic boroproline compounds

Publications (1)

Publication Number Publication Date
BR9910907A true BR9910907A (pt) 2002-02-13

Family

ID=22211956

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9910907-7A BR9910907A (pt) 1998-06-05 1999-05-14 Compostos cìclicos de boroprolina

Country Status (19)

Country Link
US (1) US6355614B1 (pt)
EP (1) EP1084129B1 (pt)
JP (1) JP2002517401A (pt)
KR (1) KR100704814B1 (pt)
AR (1) AR018440A1 (pt)
AT (1) ATE231512T1 (pt)
AU (1) AU765370B2 (pt)
BR (1) BR9910907A (pt)
CA (1) CA2334155C (pt)
DE (1) DE69905038T2 (pt)
DK (1) DK1084129T3 (pt)
ES (1) ES2189423T3 (pt)
IL (1) IL139885A (pt)
MY (1) MY122383A (pt)
NO (1) NO20006169L (pt)
NZ (1) NZ508642A (pt)
PT (1) PT1084129E (pt)
TW (1) TW575574B (pt)
WO (1) WO1999062914A1 (pt)

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WO1999062914A1 (en) 1999-12-09
EP1084129B1 (en) 2003-01-22
NZ508642A (en) 2003-10-31
AU3995899A (en) 1999-12-20
AR018440A1 (es) 2001-11-14
NO20006169L (no) 2001-02-05
US6355614B1 (en) 2002-03-12
CA2334155A1 (en) 1999-12-09
PT1084129E (pt) 2003-06-30
IL139885A (en) 2004-05-12
ES2189423T3 (es) 2003-07-01
CA2334155C (en) 2005-04-19
DE69905038D1 (de) 2003-02-27
JP2002517401A (ja) 2002-06-18
KR100704814B1 (ko) 2007-04-10
DE69905038T2 (de) 2003-06-05
DK1084129T3 (da) 2003-05-19
IL139885A0 (en) 2002-02-10
AU765370B2 (en) 2003-09-18
NO20006169D0 (no) 2000-12-04
TW575574B (en) 2004-02-11
MY122383A (en) 2006-04-29
EP1084129A1 (en) 2001-03-21
KR20010052548A (ko) 2001-06-25
ATE231512T1 (de) 2003-02-15

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