BR9912923A - Processo contìnuo para preparação de ácido n-(fosfonometil) iminodiacético - Google Patents

Processo contìnuo para preparação de ácido n-(fosfonometil) iminodiacético

Info

Publication number
BR9912923A
BR9912923A BR9912923-0A BR9912923A BR9912923A BR 9912923 A BR9912923 A BR 9912923A BR 9912923 A BR9912923 A BR 9912923A BR 9912923 A BR9912923 A BR 9912923A
Authority
BR
Brazil
Prior art keywords
stream
acid
amidocarboxymethylation
phosphonomethyl
iminodiacetic acid
Prior art date
Application number
BR9912923-0A
Other languages
English (en)
Inventor
Michael K Stern
Todd J Johnson
Amy L Jorgenson
Michael D Rogers
Thaddeus S Franczyk Iii
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR9912923A publication Critical patent/BR9912923A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO CONTìNUO PARA A PREPARAçãO DE áCIDO N-(FOSFONOMETIL)IMINODIACéTICO". No processo da presente invenção, forma-se ácido N-acetilaminodiacético via uma reação contínua de amidocarboximetilação. Nesta reação, o ácido N-(acetil)iminodiacético é formado em um sistema de reator de amidocarboximetilação, em que uma fonte de cada um dos seguintes é alimentada de maneira contínua: (1) acetamida ou um derivado de acetamida, (2) formaldeído ou um gerador ou derivado de formaldeído, (3) um catalisador de carbonilação, (4) monóxido de carbono, e, opcionalmente, (5) hidrogênio. Por sua vez, um fluxo de produto de reação de amidocarboximetilação, que contém ácido N-(acetil)-iminodiacético e o catalisador de carbonilação, é removido do sistema de reator de amidocarboximetilação. O catalisador de carbonilação é separado do fluxo de produto de reação de amidocarboximetilação para recuperar o catalisador de carbonilação e formar um fluxo de produto depletado de catalisador que contém ácido N-(acetil)iminodiacético. O catalisador de carbonilação separado é retornado ao sistema de reator de amidocarboximetilação, e o ácido N-(acetil)iminodiacético no fluxo de produto depletado de catalisador é : (1) reagido com uma fonte de fósfoto e uma fonte de formaldeído na presença de um ácido para formar um fluxo de produto de reação de fosfonometilação contendo ácido N-(fosfonometil)-iminodiacético e ácido acético; ou (2) desacilado e ciclizado para formar uma 2,5-dicetopiperazina, e, depois, reagido com uma fonte de fósforo e uma fonte de formaldeído na presença de um ácido para formar um fluxo de produto de reação de fosfonometilação contendo ácido N-(fosfonometil)-iminodiacético e ácido acético. De qualquer uma destas maneiras, o ácido N-(fosfonometil)-iminodiacético é precipitado do fluxo de produto de reação de fosfonometilação na presença de ácido acético, e o precipitado é recuperado para formar um fluxo de filtrado. O fluxo de filtrado é separado em um fluxo enriquecido com ácido acético e um fluxo depletado de ácido acético. Pelo menos uma parte do fluxo enriquecido com ácido acético é alimentada em um reator de síntese de acetamida em que se alimenta simultaneamente amónia para formar um fluxo de produto de acetamida, que é alimentado (diretamente ou indiretamente) de volta ao sistema de reator de amidocarboximetilação.
BR9912923-0A 1998-08-12 1999-08-12 Processo contìnuo para preparação de ácido n-(fosfonometil) iminodiacético BR9912923A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9620598P 1998-08-12 1998-08-12
PCT/US1999/018501 WO2000009520A1 (en) 1998-08-12 1999-08-12 Continuous process for the preparation of n-(phosphonomethyl) iminodiacetic acid

Publications (1)

Publication Number Publication Date
BR9912923A true BR9912923A (pt) 2001-10-09

Family

ID=22256348

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912923-0A BR9912923A (pt) 1998-08-12 1999-08-12 Processo contìnuo para preparação de ácido n-(fosfonometil) iminodiacético

Country Status (9)

Country Link
US (2) US6130351A (pt)
EP (1) EP1104428A1 (pt)
JP (1) JP2002522549A (pt)
CN (1) CN1319102A (pt)
AU (1) AU754281B2 (pt)
BR (1) BR9912923A (pt)
CA (1) CA2339839A1 (pt)
ID (1) ID28485A (pt)
WO (1) WO2000009520A1 (pt)

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BR9912923A (pt) * 1998-08-12 2001-10-09 Monsanto Co Processo contìnuo para preparação de ácido n-(fosfonometil) iminodiacético
KR20020073147A (ko) * 1999-12-21 2002-09-19 몬산토 테크놀로지 엘엘씨 탄소-지지된, 귀금속-함유 촉매의 존재하에 보충적촉진제의 액상 산화 반응에서의 용도
AR038654A1 (es) 2000-05-22 2005-01-26 Monsanto Technology Llc Sistemas de reaccion para producir compuestos de n-(fosfonometil) glicina
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EP1560648A1 (en) * 2002-06-28 2005-08-10 Monsanto Technology LLC Use of tellurium in carbon-supported, noble metal-containing catalysts for liquid phase oxidation reactions
GB0413092D0 (en) * 2004-06-11 2004-07-14 Degussa Process for preparing amino acids using the amidocarbonylation reaction (1)
GB0413090D0 (en) * 2004-06-11 2004-07-14 Degussa Process for preparing amino acids using the amidocarbonylation reaction (2)
AR051926A1 (es) * 2004-09-15 2007-02-21 Monsanto Technology Llc Catalizadores de oxidacion, procedimientos de preparacion de dichos catalizadores y proceso para la elaboracion de n-( fosfonometil)glicina o una sal de la misma
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AR056660A1 (es) * 2005-04-25 2007-10-17 Monsanto Technology Llc Alteracion de la distribucion de tamanos de cristales de acido n-(fosfonometil) iminodiacetico para mejorar la filtracion y la calidad del producto
TW200732292A (en) * 2006-02-01 2007-09-01 Shell Int Research A method of treating an aldehyde mixture, use of the treated aldehyde, and an alcohol
CN100400543C (zh) * 2006-09-08 2008-07-09 四川贝尔实业有限责任公司 亚氨基二乙腈水解制备双甘膦的方法
US8252953B2 (en) 2008-05-01 2012-08-28 Monsanto Technology Llc Metal utilization in supported, metal-containing catalysts
PL2493902T3 (pl) * 2009-10-27 2015-02-27 Straitmark Holding Ag Sposób wytwarzania kwasów fosfonoalkiloiminodioctowych
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EP2875036A1 (en) 2012-07-17 2015-05-27 Straitmark Holding AG Method for the synthesis of aminoalkylenephosphonic acid
BR112015000995B1 (pt) 2012-07-17 2020-04-28 Monsanto Technology Llc método para a síntese de n-(fosfonometil)glicina ou um de seus derivados selecionados a partir do grupo que consiste em seus sais, seus ésteres de fosfonato e seus sais de éster de fosfonato
RU2674022C9 (ru) 2012-07-17 2019-01-24 МОНСАНТО ТЕКНОЛОДЖИ ЭлЭлСи Способ синтеза альфа-аминоалкиленфосфоновой кислоты
BR112015000966B1 (pt) 2012-07-17 2020-04-28 Monsanto Technology Llc método para a síntese de n-(fosfonometil)glicina ou um de seus derivados selecionados a partir do grupo que consiste em seus sais, seus ésteres de fosfonato e seus sais de éster de fosfonato
RU2015103314A (ru) 2012-07-17 2016-09-10 Страйтмарк Холдинг Аг Способ синтеза N-фосфонометилиминодиуксусной кислоты
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Also Published As

Publication number Publication date
AU5485199A (en) 2000-03-06
WO2000009520A1 (en) 2000-02-24
JP2002522549A (ja) 2002-07-23
US6130351A (en) 2000-10-10
WO2000009520A9 (en) 2000-09-28
EP1104428A1 (en) 2001-06-06
AU754281B2 (en) 2002-11-14
US6278017B1 (en) 2001-08-21
ID28485A (id) 2001-05-31
CN1319102A (zh) 2001-10-24
CA2339839A1 (en) 2000-02-24

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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