BRPI0210026B8 - sistema de desintegração de formulação em pó para inaladores de pó seco e inalador - Google Patents

sistema de desintegração de formulação em pó para inaladores de pó seco e inalador

Info

Publication number
BRPI0210026B8
BRPI0210026B8 BRPI0210026A BRPI0210026A BRPI0210026B8 BR PI0210026 B8 BRPI0210026 B8 BR PI0210026B8 BR PI0210026 A BRPI0210026 A BR PI0210026A BR PI0210026 A BRPI0210026 A BR PI0210026A BR PI0210026 B8 BRPI0210026 B8 BR PI0210026B8
Authority
BR
Brazil
Prior art keywords
chamber
air
passage
powder
circulation
Prior art date
Application number
BRPI0210026A
Other languages
English (en)
Inventor
Haaije De Boer Anne
Gjaltema Doetie
Willem Frijlink Henderik
Goede Joachim
Hagedoorn Paul
Original Assignee
Almirall Sa
Astrazeneca Ab
Laboratorios Almirall S A
Meda Pharma Gmbh & Co Kg
Sofotec Gmbh & Co Kg
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Sa, Astrazeneca Ab, Laboratorios Almirall S A, Meda Pharma Gmbh & Co Kg, Sofotec Gmbh & Co Kg, Viatris Gmbh filed Critical Almirall Sa
Publication of BRPI0210026B1 publication Critical patent/BRPI0210026B1/pt
Publication of BRPI0210026B8 publication Critical patent/BRPI0210026B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)

Abstract

"sistema e método de desintegração de formulação em pó para inaladores de pó seco". a presente invenção refere-se a um mecanismo de desintegração para inaladores de pó seco, cujo propósito é o aumento da eficácia da aplicação de formulações médias em pó. o referido mecanismo compreende uma câmara de circulação de ar substancialmente cilíndrica (3) com uma altura sendo menor do que o seu diâmetro e pelo menos dois canais de suprimento de ar (2, 9), que entram na câmara (3) como tangentes a sua parede cilíndrica (5) em lados geralmente opostos dessa parede (5), adequados para criar um padrão circular de fluxo de ar no interior da câmara (3), ambos os canais de ar (2, 9) tendo entradas diferentes ou, alternativamente, compartilhando a mesma entrada, que é dividida, de modo a ter uma passagem (2) para atravessar a região de medição de dose ou de fornecimento de dose do inalador, para permitir a quantidade de pó de uma dose única arrastada para a câmara de circulação (3) pela circulação de ar através dessa passagem (2) e a outra passagem para servir como um canal de desvio (9) em direção à câmara de circulação (3) adequada para acelerar as partículas e criar um padrão de fluxo mais simétrico no interior do referido conduto de ar (3) e um método.
BRPI0210026A 2001-06-22 2002-06-15 sistema de desintegração de formulação em pó para inaladores de pó seco e inalador BRPI0210026B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10129703A DE10129703A1 (de) 2001-06-22 2001-06-22 Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
DE10129703.3 2001-06-22
PCT/EP2002/006610 WO2003000325A1 (en) 2001-06-22 2002-06-15 Powder formulation disintegrating system and method for dry powder

Publications (2)

Publication Number Publication Date
BRPI0210026B1 BRPI0210026B1 (pt) 2018-04-03
BRPI0210026B8 true BRPI0210026B8 (pt) 2021-06-22

Family

ID=7688810

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0210026A BRPI0210026B8 (pt) 2001-06-22 2002-06-15 sistema de desintegração de formulação em pó para inaladores de pó seco e inalador
BR0210026-6A BR0210026A (pt) 2001-06-22 2002-06-15 Sistema e método de desintegração de formulação em pó para inaladores de pó seco

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR0210026-6A BR0210026A (pt) 2001-06-22 2002-06-15 Sistema e método de desintegração de formulação em pó para inaladores de pó seco

Country Status (30)

Country Link
EP (1) EP1397174B1 (pt)
JP (1) JP4116537B2 (pt)
KR (1) KR100904955B1 (pt)
CN (1) CN100337699C (pt)
AR (1) AR034616A1 (pt)
AT (1) ATE477826T1 (pt)
AU (1) AU2009200071B2 (pt)
BG (1) BG66589B1 (pt)
BR (2) BRPI0210026B8 (pt)
CA (1) CA2445892C (pt)
CY (1) CY1110924T1 (pt)
CZ (1) CZ302528B6 (pt)
DE (2) DE10129703A1 (pt)
DK (1) DK1397174T3 (pt)
ES (1) ES2350973T3 (pt)
HR (1) HRP20040058B1 (pt)
HU (1) HU227457B1 (pt)
IL (3) IL158614A0 (pt)
MX (1) MXPA03011550A (pt)
NO (1) NO332992B1 (pt)
NZ (1) NZ530308A (pt)
PL (1) PL204900B1 (pt)
PT (1) PT1397174E (pt)
RU (1) RU2291717C2 (pt)
SI (1) SI1397174T1 (pt)
SK (1) SK288034B6 (pt)
TW (1) TW567075B (pt)
UA (1) UA74648C2 (pt)
WO (1) WO2003000325A1 (pt)
ZA (1) ZA200308555B (pt)

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CN117547693B (zh) * 2023-12-20 2025-08-01 上海新黄河制药有限公司 一种适用于双储库粉雾剂装置的流道
CN118575973B (zh) * 2024-06-27 2025-11-21 黑龙江飞鹤乳业有限公司 压缩食品粉末的制备方法及制备压缩食品的方法
CN118592629B (zh) * 2024-07-01 2026-01-02 广西瀛开科技有限公司 一种坚果粘壳分离装置
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HUP0400212A2 (en) 2004-06-28
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