BRPI0401977A - Processo de revestimento de stents para implante intracoronário com blenda polimérica hidrofóbica doadora de óxido nìtrico - Google Patents
Processo de revestimento de stents para implante intracoronário com blenda polimérica hidrofóbica doadora de óxido nìtricoInfo
- Publication number
- BRPI0401977A BRPI0401977A BRPI0401977A BRPI0401977A BR PI0401977 A BRPI0401977 A BR PI0401977A BR PI0401977 A BRPI0401977 A BR PI0401977A BR PI0401977 A BRPI0401977 A BR PI0401977A
- Authority
- BR
- Brazil
- Prior art keywords
- stent coating
- blending
- coating process
- donor
- polymeric
- Prior art date
Links
- 238000000576 coating method Methods 0.000 title abstract 3
- 239000007943 implant Substances 0.000 title abstract 2
- 238000002156 mixing Methods 0.000 title abstract 2
- 239000002840 nitric oxide donor Substances 0.000 title abstract 2
- 230000002209 hydrophobic effect Effects 0.000 title 1
- 238000002399 angioplasty Methods 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 2
- 208000037803 restenosis Diseases 0.000 abstract 2
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 229920001600 hydrophobic polymer Polymers 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000010118 platelet activation Effects 0.000 abstract 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 abstract 1
- 229920000728 polyester Polymers 0.000 abstract 1
- 229920002959 polymer blend Polymers 0.000 abstract 1
- 239000004926 polymethyl methacrylate Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Landscapes
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
"PROCESSO DE REVESTIMENTO DE STENTS PARA IMPLANTE INTRACORONáRIO COM BLENDA POLIMéRICA HDROFóBICA DOADORA DE óXIDO NìTRICO". Novo processo para o revestimento de stents com a blenda polimérica de poliéster polinitrosado/PMMA, com o objetivo de se obter um stent revestido com um polímero hidrofóbico doador de NO, para aplicações em angioplastia, o qual tem a finalidade de inibir a reestenose, atendendo a um grande interesse recente no desenvolvimento de materiais poliméricos atóxicos, capazes de liberar gradualmente NO, para aplicações biomédicas, de forma a previr a ativação e a adesão de plaquetas, reduzindo a proliferação das células musculares lisas, estimulando a proliferação das células endoteliais e a gênese de novos vasos e promovendo a vasodilatação dos vasos sanguíneos, uma vez que a liberação local de NO a partir da superfície de stents revestidos tem grande potencial na prevenção da trombose, podendo também reduzir a reestenose após a angioplastia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0401977A BRPI0401977B1 (pt) | 2004-04-26 | 2004-04-26 | processo de revestimento de stents para implante intracoronário com blenda polimérica hidrofóbica doadora de óxido nítrico |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0401977A BRPI0401977B1 (pt) | 2004-04-26 | 2004-04-26 | processo de revestimento de stents para implante intracoronário com blenda polimérica hidrofóbica doadora de óxido nítrico |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0401977A true BRPI0401977A (pt) | 2005-12-20 |
| BRPI0401977B1 BRPI0401977B1 (pt) | 2015-11-17 |
Family
ID=35521083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0401977A BRPI0401977B1 (pt) | 2004-04-26 | 2004-04-26 | processo de revestimento de stents para implante intracoronário com blenda polimérica hidrofóbica doadora de óxido nítrico |
Country Status (1)
| Country | Link |
|---|---|
| BR (1) | BRPI0401977B1 (pt) |
-
2004
- 2004-04-26 BR BRPI0401977A patent/BRPI0401977B1/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0401977B1 (pt) | 2015-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B03A | Publication of an application: publication of a patent application or of a certificate of addition of invention | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
| B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
| B06A | Notification to applicant to reply to the report for non-patentiability or inadequacy of the applcation according art. 36 industrial patent law | ||
| B09A | Decision: granting | ||
| B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/11/2015, OBSERVADAS AS CONDICOES LEGAIS. |