BRPI0404983A - composições imunogênicas - Google Patents

composições imunogênicas

Info

Publication number
BRPI0404983A
BRPI0404983A BRPI0404983A BRPI0404983A BR PI0404983 A BRPI0404983 A BR PI0404983A BR PI0404983 A BRPI0404983 A BR PI0404983A BR PI0404983 A BRPI0404983 A BR PI0404983A
Authority
BR
Brazil
Prior art keywords
antigen
days
protein
immunogenic compositions
present
Prior art date
Application number
Other languages
English (en)
Inventor
Jose Maciel Junior Rodrigues
Karla De Melo Lima
Original Assignee
Nanocore Biotecnologia Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanocore Biotecnologia Ltda filed Critical Nanocore Biotecnologia Ltda
Priority to BRPI0404983 priority Critical patent/BRPI0404983A/pt
Priority to PCT/BR2005/000179 priority patent/WO2006024122A1/en
Priority to EP05782989A priority patent/EP1858547A1/en
Priority to AU2005279641A priority patent/AU2005279641A1/en
Publication of BRPI0404983A publication Critical patent/BRPI0404983A/pt
Priority to ZA200702752A priority patent/ZA200702752B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

"COMPOSIçõES IMUNOGêNICAS". A presente invenção descreve composições capazes de estimular uma resposta imune em um hospedeiro inoculado com um antígeno de interesse e um vetor gênico, onde dita composição compreende microesferas baseadas em co-polímeros derivados do ácido lático e do ácido glicólico, encapsulando antígenos e vetores gênicos e adjuvantes estimuladores de citocinas. Uma concretização da presente invenção é o uso de plasmídeos codificando genes de proteína de Mycobacteriuin e a proteína recombinante encapsulados em microesferas de PLGA onde o DNA é liberado em um período máximo de 30 dias e a liberação do segundo antígeno (peptídeo, proteína, ou outro) tem uma liberação sustentada por período superior a 30 dias.
BRPI0404983 2004-09-03 2004-09-03 composições imunogênicas BRPI0404983A (pt)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BRPI0404983 BRPI0404983A (pt) 2004-09-03 2004-09-03 composições imunogênicas
PCT/BR2005/000179 WO2006024122A1 (en) 2004-09-03 2005-09-05 Immunogenic compositions
EP05782989A EP1858547A1 (en) 2004-09-03 2005-09-05 Immunogenic compositions
AU2005279641A AU2005279641A1 (en) 2004-09-03 2005-09-05 Immunogenic compositions
ZA200702752A ZA200702752B (en) 2004-09-03 2007-04-02 Immunogenic compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0404983 BRPI0404983A (pt) 2004-09-03 2004-09-03 composições imunogênicas

Publications (1)

Publication Number Publication Date
BRPI0404983A true BRPI0404983A (pt) 2006-05-02

Family

ID=35999654

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0404983 BRPI0404983A (pt) 2004-09-03 2004-09-03 composições imunogênicas

Country Status (5)

Country Link
EP (1) EP1858547A1 (pt)
AU (1) AU2005279641A1 (pt)
BR (1) BRPI0404983A (pt)
WO (1) WO2006024122A1 (pt)
ZA (1) ZA200702752B (pt)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
AU9588398A (en) * 1997-09-29 1999-04-23 Beth Israel Deaconess Medical Center Vaccine compositions and methods of enhancing vaccine efficacy
WO2000004876A2 (en) * 1998-07-23 2000-02-03 Johns Hopkins University School Of Medicine Controlled release of bioactive substances
US6998393B2 (en) * 2000-06-23 2006-02-14 Biopharm Solutions, Inc. Aquespheres, their preparation and uses thereof
DE60335608D1 (de) * 2002-02-27 2011-02-17 Pharmain Corp Zusammensetzungen zur abgabe von therapeutika und anderen materialien und verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
ZA200702752B (en) 2008-09-25
EP1858547A1 (en) 2007-11-28
WO2006024122A1 (en) 2006-03-09
AU2005279641A1 (en) 2006-03-09

Similar Documents

Publication Publication Date Title
ES2263668T3 (es) Composicion de vacuna que comprende un antigeno y un peptido con propiedades adyuvantes.
Honko et al. Effects of flagellin on innate and adaptive immunity
EP1363660A4 (en) HIGHER MOLECULAR VACCINE BASED ON AUTOMPLICATIVE RNA, SUICIDE DNA OR UNDNA DNA VECTOR, WHICH LINKS ANTIGEN WITH A POLYPEPTIDE WHICH PROMOTES THE PRESENTATION OF THE ANTIGEN
WO2007089870A3 (en) Vaccine delivery compositions and methods of use
DE60118228D1 (de) Mikropartikel zur verabreichung von heterologen nukleinsäure
IL182357A0 (en) Malaria prime/boost vaccines
JP2017525336A5 (pt)
BR0103887A (pt) Composições imunogênicas contendo microesferas biodegradáveis encapsulando antìgenos, vetores gênicos e adjuvantes
WO2005081716A3 (en) DNA VACCINES TARGETING ANTIGENS OF THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS-CoV)
JP2006514549A5 (pt)
BRPI0407840B8 (pt) vírus do sarampo recombinante, composição farmacêutica, uso de uma composição farmacêutica, célula bacteriana, método para produzir um vírus recombinante e uso
BRPI0404983A (pt) composições imunogênicas
JP2004536107A5 (pt)
Roopngam et al. Hepatitis C virus E2 protein encapsulation into poly d, l-lactic-co-glycolide microspheres could induce mice cytotoxic T-cell response
Heit et al. Vaccine protocols for enhanced immunogenicity of exogenous antigens
JP2012526519A5 (pt)
ATE435660T1 (de) Immunogenes polypeptid bestehend aus optimierten kryptischen peptiden aus tumorantigenen und seine verwendungen
BRPI0417286A (pt) misturas de peptìdeos ou polipeptìdeo antigênicos, peptìdeos antigênicos, polipeptìdeo antigênico, misturas antigênicas, lipopeptìdeo, mixotopo, lipomixotopo, conjugado, composições imunogênicas, vacina contra malária, uso de uma mistura, soro policlonal, anticorpo humano recombinante, usos de uma composição, medicamento, métodos e kits para o diagnóstico in vitro de malária, seqüências de nucleotìdeo, vetor de clonagem e/ou expressão recombinante, uso de um vetor de expressão vacina de dna e célula hospedeira recombinante
EP1557466A4 (en) TUMORANT PROPERTIES AND USE THEREOF
NR Microbial Proteomics Approach for Synthetic Vaccine Development form Bacillus Weihenstephanensis
JP2013513549A5 (pt)
EP2987502A1 (en) Peptide adjuvants
BR0209854A (pt) Molécula de ácido nucléico recombinante, cassete de expressão, vetor, polipeptìdeo, composição de vacina, dispositivo de aceleração de partìcula, e, método para gerar uma resposta imune celular em um indivìduo
CN1809584B (zh) 含有阳离子微粒和hcv e1e2 dna的组合物及其使用方法
WO2010089940A1 (ja) 粘膜ワクチン

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B04C Request for examination: application reinstated [chapter 4.3 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08E Application fees: payment of additional fee required [chapter 8.5 patent gazette]

Free format text: COMPLEMENTAR 4A., 5A., 6A., 7A. E 8A. ANUIDADES DE ACORDO COM TABELA VIGENTE REF. AS GUIAS NOS. 220708387486, 220807410702, 220906972687, 221006531100 E 220708387486, RESPECTIVAMENTE E COMPROVAR O RECOLHIMENTO DA 3A. ANUIDADE.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A TAXA DE RESTAURACAO DA 3A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2249 DE 11/02/2014.