BRPI0407611A - anti-cancer agent comprising protein lk8 as an active ingredient - Google Patents
anti-cancer agent comprising protein lk8 as an active ingredientInfo
- Publication number
- BRPI0407611A BRPI0407611A BRPI0407611-7A BRPI0407611A BRPI0407611A BR PI0407611 A BRPI0407611 A BR PI0407611A BR PI0407611 A BRPI0407611 A BR PI0407611A BR PI0407611 A BRPI0407611 A BR PI0407611A
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- active ingredient
- cancer agent
- agent
- cancer
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 4
- 239000004480 active ingredient Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 abstract 3
- 206010027476 Metastases Diseases 0.000 abstract 2
- 230000009401 metastasis Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"AGENTE ANTI-CáNCER COMPREENDENDO PROTEINA LK8 COMO UM INGREDIENTE ATIVO". A presente invenção se refere a um agente anti-câncer compreendendo proteina LK8 como um ingrediente ativo. O agente anti-câncer da presente invenção é efetivo para reprimir crescimento e metástase de tumor maligno. Desse modo, o agente pode ser efetivamente usado não somente como repressor de metástase de câncer, mas também como agente terapêutico de tumor malígno primário."ANTI-CANCER AGENT UNDERSTANDING LK8 PROTEIN AS AN ACTIVE INGREDIENT". The present invention relates to an anti-cancer agent comprising LK8 protein as an active ingredient. The anti-cancer agent of the present invention is effective for suppressing malignant tumor growth and metastasis. Thus, the agent can be effectively used not only as a cancer metastasis repressor but also as a primary malignant tumor therapeutic agent.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020030010797A KR100595364B1 (en) | 2003-02-20 | 2003-02-20 | Anticancer agent containing L8 protein as an active ingredient |
| PCT/KR2004/000357 WO2004073730A1 (en) | 2003-02-20 | 2004-02-20 | Anticancer agent comprising lk8 protein as an active ingredient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0407611A true BRPI0407611A (en) | 2006-02-14 |
Family
ID=36116045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0407611-7A BRPI0407611A (en) | 2003-02-20 | 2004-02-20 | anti-cancer agent comprising protein lk8 as an active ingredient |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1608395A4 (en) |
| JP (1) | JP2006518342A (en) |
| KR (1) | KR100595364B1 (en) |
| CN (1) | CN100546646C (en) |
| AU (1) | AU2004212856B2 (en) |
| BR (1) | BRPI0407611A (en) |
| CA (1) | CA2516172A1 (en) |
| RU (1) | RU2306147C2 (en) |
| WO (1) | WO2004073730A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7285277B2 (en) | 2002-03-15 | 2007-10-23 | Mogam Biotechnology Research Institute | Anticancer agent |
| AU2003292696A1 (en) | 2002-12-26 | 2004-08-10 | Takeda Pharmaceutical Company Limited | Metastin derivative and use thereof |
| EP1713511B1 (en) * | 2004-01-09 | 2011-11-09 | Mogam Biotechnology Research Institute | Therapeutic agent for treatment of cancer comprising human apolipoprotein (a) kringles lk68 or lk8 genes as effective ingredient, and method for treating cancer using the same |
| MXPA06014206A (en) | 2004-06-25 | 2007-02-14 | Takeda Pharmaceutical | Metastin derivatives and use thereof. |
| US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| TWI386417B (en) | 2005-12-22 | 2013-02-21 | Takeda Pharmaceutical | Metastin derivatives and use thereof |
| TWI404726B (en) | 2006-10-25 | 2013-08-11 | Takeda Pharmaceutical | Metastin derivatives and use thereof |
| KR100888022B1 (en) * | 2006-12-21 | 2009-03-09 | 재단법인 목암생명공학연구소 | Fusion protein between immunoglobulin Fc and human apolipoprotein (a) kringle fragment L8 8Fc |
| FR2919064B1 (en) * | 2007-07-19 | 2009-10-02 | Biomerieux Sa | METHOD OF ASSAYING APOLIPOPROTEIN ALL FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER |
| FR2919062B1 (en) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | METHOD OF DETERMINING AMINOACYLASE 1 FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER. |
| FR2919061B1 (en) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | METHOD OF DOSING PLASTINE-I FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER. |
| FR2919065B1 (en) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | METHOD FOR DETERMINING APOLIPOPROTEIN AI FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER |
| ES2565512T3 (en) | 2007-07-19 | 2016-04-05 | bioMérieux | Test procedure for liver fatty acid binding protein, ACE and CA19-9 for in vitro diagnosis of colorectal cancer |
| FR2919063B1 (en) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | METHOD OF DETERMINING LEUCOCYTE ELASTASE INHIBITOR FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER. |
| FR2919060B1 (en) | 2007-07-19 | 2012-11-30 | Biomerieux Sa | METHOD OF DETERMINING EZRINE FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER |
| FR2933773B1 (en) | 2008-07-10 | 2013-02-15 | Biomerieux Sa | METHOD FOR DETERMINING THE ISOMERASE DISULFIDE PROTEIN FOR IN VITRO DIAGNOSIS OF COLORECTAL CANCER |
| WO2012067427A2 (en) * | 2010-11-16 | 2012-05-24 | 재단법인 목암생명공학연구소 | Pharmaceutical composition containing lk8 protein as an active ingredient for preventing or treating diabetic retinopathy or age-related macular degeneration |
| CN121712509A (en) | 2023-05-04 | 2026-03-20 | 锐新医药公司 | Combination therapy for RAS related diseases or conditions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU774759B2 (en) * | 1999-09-15 | 2004-07-08 | Mogam Biotechnology Research Institute | A novel angiogenesis inhibitor |
-
2003
- 2003-02-20 KR KR1020030010797A patent/KR100595364B1/en not_active Expired - Fee Related
-
2004
- 2004-02-20 WO PCT/KR2004/000357 patent/WO2004073730A1/en not_active Ceased
- 2004-02-20 EP EP04713257A patent/EP1608395A4/en not_active Withdrawn
- 2004-02-20 AU AU2004212856A patent/AU2004212856B2/en not_active Ceased
- 2004-02-20 JP JP2006500650A patent/JP2006518342A/en not_active Withdrawn
- 2004-02-20 CN CNB2004800048895A patent/CN100546646C/en not_active Expired - Fee Related
- 2004-02-20 RU RU2005129273/15A patent/RU2306147C2/en not_active IP Right Cessation
- 2004-02-20 CA CA002516172A patent/CA2516172A1/en not_active Abandoned
- 2004-02-20 BR BRPI0407611-7A patent/BRPI0407611A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100595364B1 (en) | 2006-07-03 |
| CA2516172A1 (en) | 2004-09-02 |
| AU2004212856B2 (en) | 2007-07-19 |
| CN100546646C (en) | 2009-10-07 |
| JP2006518342A (en) | 2006-08-10 |
| RU2306147C2 (en) | 2007-09-20 |
| EP1608395A4 (en) | 2007-10-31 |
| RU2005129273A (en) | 2006-03-10 |
| CN1753685A (en) | 2006-03-29 |
| EP1608395A1 (en) | 2005-12-28 |
| WO2004073730A1 (en) | 2004-09-02 |
| AU2004212856A1 (en) | 2004-09-02 |
| KR20040075270A (en) | 2004-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 10A, 11A, 12A E 13A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |